The life cycle of physical assets analysis is a tool of great importance for asset management and of great use to managers, namely hospital facilities and equipment managers. Furthermore, this is an essential issue in the current macroeconomic economy, being its assertiveness preponderant for the success of any investment. This paper aims to emphasize the importance of investment analysis in the decision-making strategy of any organization, intertwined with the life cycle of the physical asset analysis, framed in a structuring approach of certification by the ISO 55001 standard. For an efficient physical assets management, in general, and within the health sector, in particular, optimizing their maintenance and determining the optimal moment for their withdrawal from operation, or their renewal, are fundamental aspects for its profitability and quality of service to users. This paper brings an integrated approach, in the previous aspect, aiming to reconcile the perspective of the stakeholders, within the scope of the life cycle of assets analysis, with of the physical assets manager, in a long-term vision adjusted to the organization strategic plan. Additionally, the issue of waste elimination will also be addressed through the implementation of an Organization and Management Philosophy inspired by the practices and results of the Toyota model (TPS, Toyota Production System), which can be applied across any Organization, including the health area. In essence, the objective of applying this philosophy in hospital management is the same as what has already been achieved in industry and other sectors: the search for continuous improvement through the elimination of unnecessary activities and waste, which only increase costs, leave the Organization less competitive and impair quality.