Steroids from Monascus purpureus metabolite

ArticleinZhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 34(14):1809-11 · July 2009with1 Read
Source: PubMed


    To study the chemical constituents of Monascus purpureus metabolite.
    The compounds were isolated by column chromatography methods, and their structures were determined by spectroscopic methods.
    Eight compounds were isolated from the petroleum ether fraction of ethanolic extract and elucidated as stigmast-4-en-3-one (1), 3-oxo-24-methylenecycloarane (2), stigmasterol (3), 7beta-hydroxystigmasterol (4), 3beta-hydroxystigmast-5-en-7-one (5), 3beta-hydroxystigmast-5,22-dien-7-one (6), 5alpha, 8alpha-epidioxyergosta-6,22-dien-3beta-ol (7), sitosterol (8).
    All of the compounds were isolated from this genu for the first time except compound 3 and 7.