No full-text available
To read the full-text of this research,
you can request a copy directly from the authors.
ASSESSING THE IMPACT OF CHRONIC DERMATOLOGICAL CONDITIONS ON QUALITY OF LIFE: A CROSS-SECTIONAL STUDY UTILIZING THE DERMATOLOGY LIFE QUALITY INDEX (DLQI)"
ResearchGate has not been able to resolve any citations for this publication.
Objectives:
To assess the quality of life (QoL) of patients with different dermatological diseases. Multiple international studies have evaluated the QoL among patients with different dermatological diseases; however, few studies of this kind have been conducted in Saudi Arabia.
Methods:
This quantitative, observational, cross-sectional study was carried out in the dermatology outpatient clinics of King Saud University Medical City, Riyadh, Saudi Arabia, from September 2019 until February 2020. Data was collected using the validated Arabic version of the Dermatology of Life Quality Index (DLQI).
Results:
A total of 391 patients ≥18 years participated in the study. The mean age of participants was 33 years (18-75 years). Most participants in this study reported that their dermatological disease had a small or no effect on their QoL (62.5%). The majority of patients who had acne vulgaris (79.7%), vitiligo (79.3%), hair disorders (76.9%), or rosacea (71.5%) reported a small to no effects on their QoL. However, diseases that reflected the largest percentages of a large to extremely large effect on QoL were urticaria (37.1%), eczema (26.6%), and psoriasis (24%). A total of 42.9% of the participants suffered from lichen planus and 66.7% of participants suffered from cutaneous neoplasms reported a moderate effect on their QoL.
Conclusion:
Understanding the impact of different dermatological diseases on QoL can help dermatologists to improve thier patients' QoL. Therefore, we recommend that further studies on this topic be conducted in multiple health centers.
Objective: The purpose of the study was to determine the impact of mild to moderate acne vulgaris on quality of life (QoL) and to assess the effect of oral doxycycline and topical 5% benzoyl peroxide treatment on QoL. Patients and methods: One hundred patients, of either sex, suffering from mild to moderate acne vulgaris, were asked to fill the Dermatology Life Quality Index (DLQI) pro forma (Urdu and English version) independently before starting the treatment. The total score ranged from 0-30. The higher the score, the greater was the impact on QoL. All the patients were subjected to oral doxycycline 100 mg daily and were asked to apply 5% benzoyl peroxide once daily. Patients used these medicines for a period of three months, after which they were again asked to fill the DLQI pro forma. The data were analyzed after compiling the results. Results: The results of 100 patients, who completed the study, were compiled. The mean age of patients was 20.45±3.27 years. Among 20 male patients, 8 suffered from grade 1 and 12 from grade 2 acne. Among 80 female patients, 9 suffered from grade 1 and 71 from grade 2 (p=0.012), showing a significant association between grading of acne with respect to gender of the patient. The disease was notably severe among females. Duration and progression of disease showed no significant effect on QoL. Before treatment, the mean DLQI score for females was 14.05±6.32 with minimum score of 1 and maximum score of 25. The mean score for male patients was 12.63±6.46 with minimum score of 1 and maximum of 26, showing that QoL is worse among females as compared to males. The mean pretreatment score was 12.92± 6.43. The score dropped to 5.34±3.14 (p=0.000) after treatment showing that there is a significant improvement in quality of life of these patients. Conclusion: The study shows that mild to moderate acne vulgaris has a very large effect on the quality of life of our patients with significant psychosocial limitations. The combination treatment of oral doxycycline and topical 5% benzoyl peroxide significantly improves the quality of life in acne patients.
The goal of this study was to compare depression and quality of life in three auto immune diseases: psoriasis, vitiligo, and alopecia areata. From January 2009 until January 2010, 300 patients (100 with alopecia areata, 100 with psoriasis and 100 with vitiligo) who were randomly selected (by simple random selection) from outpatient clinic of Razi Hospital (Center of Skin Diseases of Tehran University of Medical Sciences) were asked to answer to Beck Depression Inventory (BDI), SF-36 and Dermatology Life Quality Index (DLQI) questionnaires. DLQI scores were significantly higher in psoriasis cases than others (12.8 ± 6.1, P<0.0001) and SF-36 score were significantly lower (59.8 ± 19.5, P=0.007), both indicating poor quality of life. Significant correlation was found between DLQI and BDI in all disease groups (r=0.44, P<0.001). BDI scores were the highest in psoriasis group but this difference was not significant (P=0.2). Based on these results, dermatologists should consider psychological aspects of autoimmune skin diseases.
To assess the level of quality of life (QOL) in patients suffering from various cardiac, cancer, hepatic, and dermatological diseases.
A total of 339 patients of cardiac, cancer, hepatic, and dermatological diseases from DHQ/Allied hospitals of Faisalabad participated in this study through purposive convenient sampling technique. Quality of life was measured by WHO QOL-BREF (Validated Urdu Version) while demographic variables were recorded on a demographic sheet. The results were obtained by using analysis of variance (ANOVA) on SPSS 13.
Out of 339, 156 (46%) patients were males while 183 (54%) patients were females. Of the total, 99 (29.2%) belonged to the lower socio economic status, 113 (33.3%) belonged to the lower middle, 62 (18.3%) belonged to the middle, and 65 (19.2%) belonged to the upper middle socio economic status. In terms of education, 49 (14.5%) were illiterate, 110 (32.3%) had primary level education, 118 (34.8%) had middle level education, 21 (6.2%) had done matriculation, 17 (5%) had intermediate, 14 (4.1%) were graduates, 8 (2.4%) had done masters. Of the whole lot, only 2 (0.6%) patients were professionals. Results showed that the quality of life was most deteriorated in the domain of physical health; while psychological health was the second most deteriorated domain. Social relationship was the least affected domain, while environment was the second least affected area. Quality of life of hepatic patients was significantly lower than dermatological patients with respect to physical health and environment, lower than cancer patients in relation to psychological health, and lower than cardiac patients in the social relationship domain. The quality of life of cardiac patients was noted to be significantly higher than the other three categories in the domains of psychological health and environment.
In the face of the evidence of high deterioration in the quality of life of the patients in terms of physical and psychological health, medical units should be better equipped with facilities to enhance a sense of betterment in patients. The treating doctors should be better trained to give due consideration to this important aspect of management. Moreover, the role of liaison psychiatry should also be incorporated.
Objective To detect the impact of acne vulgaris on quality of life and assess correlation between disease severity, complications and decreased life quality. Methods This cross-sectional study of one-year duration involving acne patients of 18-30 years was carried out after institutional Ethics Committee clearance. After written informed consent, patients filled a proforma including demographic data, treatment and previous psychiatric history. Clinical grade of acne and severity of pigmentation and scarring were noted. Acne severity was classified as mild, moderate or severe and DLQI was noted. Statistical analysis was performed with the Statistical Package for the Social Sciences (SPSS version 15.0), Chi-square test and Pearson's correlation coefficient. Results Overall mean DLQI was 7.84 (females 8.02, males 7.82) showing no significant difference between the genders. There was no association seen between DLQI scores severity and complications like pigmentation (p=0.198) and scarring (p=0.095). There was significant association between severity of acne grades and DLQI scores (p=0.014). Limitation The study population was restricted to patients visiting our outpatient department. Only DLQI questionnaire was used for evaluation, which could detect psychosocial problems, but not depression or anxiety without clinical assessment. Conclusion Our study confirms a negative impact of acne on quality of life substantiating a holistic approach treating physique and psyche for well-being of the person. © 2018 Pakistan Association of Dermatologists. All rights reserved.
Background: Distal and lateral subungual onychomycosis (DLSO) is the most common clinical type of onychomycosis. The disease causes little physical handicap but it has a devastating effect on quality of life (QOL) particularly in our set up. Objective: The purpose of the study was to assess the effect of itraconazole pulse therapy on quality of life in Pakistani patients with DLSO. Methods: Sixty-two patients, 47 males and 15 females suffering from DLSO, age range 19 to 55 years, who were themselves able to understand and fill the questionnaire related with general and disease-specific QOL in English or Urdu version, were enrolled in the study. The total score ranged from 0-60. The higher the score, the greater was the impact on QOL. The patients were subjected to itraconazole pulse therapy and each pulse consisted of 200 mg twice a day for 7 days, followed by a drug-free interval of three weeks. Two pulses were given for fingernail onychomycosis and three pulses for toenail infection. The pre- and post-trial data was analyzed before and after therapy in 46 finger- and 16 toenail cases of DLSO. Results: The disease caused psychosocial problems (92%), economic problems in treatment (89.4%), difficulty in cutting nails (62.9%), physical contact problems with hands (60.8%), discomfort in wearing shoes and walking (56.2%), pain (33.8%), disturbance of work with hands (30.4%) and affected performance in sports (22.5%). After itraconazole pulse therapy, these problems decreased to 12.9%, 14.5%, 6.45%, 6.4%, 12.5%, 4.8%, 6.45% and 3.2%, respectively. The mean pretreatment score in patients with finger- and toenail disease was 32±3.4 and 29±4.5, respectively. The score dropped to 4.3±5.4 and 4.4±5.6 (P<0.05) after itraconazole therapy at last follow-up 32 weeks and 48 weeks for finger- and toenail disease, respectively. Fingernail disease has affected QOL more than toenail disease and longer duration of disease, greater involvement of individual nails and greater number of nails involved was also associated with more serious impact on QOL. Females were found to be more psychologically upset than males. Conclusion: Itraconazole pulse therapy significantly improves the QOL in disto-lateral subungual onychomycosis of both finger- and toenails in our patients.
A simple practical questionnaire technique for routine clinical use, the Dermatology Life Quality Index (DLQI) is described. One hundred and twenty patients with different skin diseases were asked about the impact of their disease and its treatment on their lives; a questionnaire, the DLQI, was developed based on their answers. The DLQI was then completed by 200 consecutive new patients attending a dermatology clinic. This study confirmed that atopic eczema, psoriasis and generalized pruritus have a greater impact on quality of life than acne, basal cell carcinomas and viral warts. The DLQI was also completed by 100 healthy volunteers; their mean score was very low (1.6%, s.d. 3.5) compared with the mean score for the dermatology patients (24.2%, s.d. 20.9). The reliability of the DLQI was examined in 53 patients using a 1 week test-retest method and reliability was found to be high (gamma s = 0.99).
Skin diseases cause considerable discomfort, but usually do not affect patients' lifespan. However the effects of skin disease on patients' lives can be profound, as all aspects of life can be interfered with. Methods to measure these effects on life quality are needed for clinical, research, audit and political reasons. General health questionnaires such as the Sickness Impact Profile or the Short Form 36 can be used to compare the impact of skin disease to the impact of diseases of other systems. Disease specific questionnaires such as the Psoriasis Disability Index, dermatology specific measures such as the Dermatology Life Quality Index (DLQI), and utility measures can all be used in dermatology and have their different specific indications. The use of the DLQI has quantified the major impact that inflammatory skin disease has on patients and has been used to demonstrate the improvement resulting from systemic therapy and from inpatient management. A version for use in children has also been described. The information gained from this work can be used to demonstrate the importance of adequately managing skin disease in the community and can help to guide resource allocation.
outcome measures, quality of life, questionnaire, skin disease, validation
Quality of life in patients with acnevulgaris
- F Asad
- A Qadir
- M Nadeem
Asad F, Qadir A, Nadeem M. Quality of life in patients with acnevulgaris. J Coll Physicians
SurgPak. 2002; 12:654-6.