Exploring Human Comedogenic Potential

Abstract

Cosmetic products are topical preparations widely used for cleansing, beautifying, promoting attractiveness or altering the appearance of body without affecting its structure or functions.
Researches have shown that the frequent use of several cosmetics is linked to formation of comedones and acne because these products typically contain ingredients such as artificial colours, oils, fragrances, and preservatives that can exacerbate acne-prone or oily skin. These comedogenic ingredients can lead to the accumulation of sebum, bacteria and dead skin cells within the pores, resulting in the formation of comedones (blackheads and whiteheads) and acne lesions, thereby influencing the overall health and appearance of the skin. Products identified as non-comedogenic aim to minimize the risk of pore blockage, promoting clear and healthy skin. Non-comedogenic claims are frequently integrated into cosmetic marketing and labelling strategies. The execution of non-comedogenicity studies enables manufacturers to validate such claims, aligning their products with professional and regulatory standards. These studies play a crucial role in cultivating trust among consumers by providing scientific evidence that supports the safety of these products for the skin.
NovoBliss Research Private Limited, Gujarat, India, operating as a Contract Research Organization (CRO), specializes in claims substantiation for widely used cosmeceuticals, pharmaceuticals, dietary supplements, herbal, ayurvedic, nutraceuticals, and FMCG products. For conducting non-comedogenicity studies, our focus lies in employing the well-known "Cyanoacrylate Follicular Biopsy Analysis" technique. These assessments involve the evaluation of skin conditions before and after one month of cosmetic product usage.