Education management information systems (EMIS) play a critical role in providing quality data for effective decision making and design of appropriate interventions. Over the last two decades, the health sector in low and middle-income countries (LMICs) has seen the emergence of robust and responsive health management information systems (HMIS). On the contrary, the education sector lacks comprehensive and flexible information systems for reporting and management of key education data, resulting in fragmentation and limited education data use above the school level. Against this backdrop, this paper presents key lessons from the implementation of a standardized HMIS in the health sector in Uganda, which has informed the implementation of a decentralized EMIS. Drawing from an action research approach to EMIS strengthening in Uganda, we provide guidance to education managers and policy makers in LMICs seeking to enhance education data standardization, management and use.