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Abstract citation ID: ckad133.084
O.1.1-8 Impact on health-related quality of life after
a concurrent exercise program in adults with
treatment resistant depression: TRACE-RMD study
Jose
´Etxaniz-Ose
´s
1
, Mikel Tous-Espelosin
2,3
, Nagore Iriarte-Yoller
4,5
,
Sara Maldonado-Martin
2,3
1
Department of Physical Education and Sport, Faculty of Education and
Sport-Physical Activity and Sport Sciences Section, University of the Basque
Country (UPV/EHU), Vitoria-Gasteiz, Araba/A
´lava, Basque Country, Spain
2023 HEPA Europe Conference i33
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2
Gizartea, Kirola eta Ariketa Fisikoa Ikerkuntza Taldea (GIKAFIT), Society,
Sports, and Physical Exercise Research Group, Department of Physical
Education and Sport, Faculty of Education and Sport- Physical Activity and
Sport Sciences Section, University of the Basque Country (UPV/EHU),
Vitoria-Gasteiz, Araba/A
´lava, Basque Country, Spain
3
Bioaraba Health Research Institute, Physical Activity, Exercise, and Health
Group, Vitoria-Gasteiz. Araba/A
´lava, Basque Country, Spain
4
Bioaraba Health Research Institute, New Therapies in Mental Health
Group, Vitoria-Gasteiz, Spain, Osakidetza Basque Health Service, Araba
Mental Health Network, Psychiatric Hospital of Alava, Vitoria-Gasteiz, Spain
5
Department of Medicine, Faculty of Health Sciences, University of Deusto,
Bilbao, Spain; jechaniz012@ikasle.ehu.eus
Purpose
Treatment-resistant depression (TRD) is defined as those who
do not remit to major depressive disorder with pharmacolo-
gical treatment. TRD is associated with a worse health-related
quality of life (QoL). Thus, people with TRD have reported
greater disability than those healthy control (HC) in QoL,
assessed by the 36-Item Short-Form Health Survey question-
naire (SF-36). Concurrent exercise training (i.e., a combina-
tion of aerobic and resistance exercise in the same session)
could be an efficient non-pharmacological treatment strategy
for improving QoL. Exercise is recommended as a non-
pharmacological adjuvant program for patients with TRD.
Therefore, this study aimed to determine the effectiveness of a
concurrent exercise program on QoL in a TRD population.
Methods
Participants (n = 15, 73.3% women, 57.713.7 yr old) with
TRD carried out a concurrent exercise program (2 days/week
and 12 weeks of intervention). The SF-36 questionnaire was
used to assess health-related QoL. At baseline, the TRD
population showed lower scores (P 0.001) in physical
function, role-physical, bodily pain, general health, vitality,
social functioning, emotional role, mental health, and physical
and mental component summaries compared to HC.
Results
After 12-week of intervention, general health ("50.5%), vitality
("41.2%), social functioning ("76.4%), and mental compo-
nent summary ("24.9%) were increased (P < 0.05). However,
there was not a significant (P > 0.05) change increase in
physical functioning, role physical, bodily pain, emotional role,
mental health, and physical component summary.
Conclusion
In conclusion, beneficial effects on QoL variables in patients
with TRD after concurrent exercise should lead to considering
exercise as an adjuvant program in their treatment.
i34 European Journal of Public Health, Vol. 33, Supplement 1, 2023
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