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Cannabis sativa: Industrial hemp (fiber type) -An Ayurvedic Traditional Herbal Medicine

Authors:
  • Mangalore University, Mangalore, Karnataka India

Abstract

This review paper highlights the medicinal importance of the hemp and hemp based products, hemp seeds, hemp oil, and hemp used in food products. Based on the literature review performed, there is a significant scientific evidence that provides support for the usage of Cannabis sativa as a traditional phytomedicine by folk medicine practitioners of India. According to Ayuverda in India, the medicinal value of the Cannabis plants was well documented more than 3,000 years ago. The earliest written reference to Cannabis in India may occur in the Atharvaveda. India is the land of pharmacy and known for Ayurvedic medicine. Hemp was mentioned in Ayurveda, as one of the medicinal plant used for many diseases. There are many growing customers across India and around the world. This will help to boost the Indian economy and increase the productivity of the Indian hemp (fiber type).
International Journal of Innovation Scientific Research and Review
Vol. 05, Issue, 02, pp.4040-4046, February 2023
Available online at http://www.journalijisr.com
SJIF Impact Factor 2022: 5.039
Research Article
ISSN: 2582-6131
CANNABIS SATIVA: Industrial hemp (fiber type) - An Ayurvedic Traditional Herbal Medicine
1, * Ravindra B. Malabadi, 2Kiran P. Kolkar, 1Raju K. Chalannavar
1Department of Applied Botany, Mangalore University, Mangalagangotri-574199, Mangalore, Karnataka State, India.
2Department of Botany, Karnatak Science College, Dharwad-580003, Karnataka State, India.
Received 28th December 2022; Accepted 29th January 2023; Published online 28th February 2023
ABSTRACT
This review paper highlights the medicinal importance of the hemp and hemp based products, hemp seeds, hemp oil, and hemp used in food
products. Based on the literature review performed, there is a significant scientific evidence that provides support for the usage of Cannabis sativa as a
traditional phytomedicine by folk medicine practitioners of India. According to Ayuverda in India, the medicinal value of the Cannabis plants was well
documented more than 3,000 years ago. The earliest written reference to Cannabis in India may occur in the Atharvaveda. India is the land of pharmacy and
known for Ayurvedic medicine. Hemp was mentioned in Ayurveda, as one of the medicinal plant used for many diseases. There are many growing Indian
companies (Bombay Hemp Company, BOHECO, Satliva, Hemp Fabric Lab, Vedi, Happy Hemp, SUI, Its Hemp, Bhu:Sattva’s, Health Horizons, Hemis,
Hemp Republic, Hempsters, B.E. Hemp, India Hemp Co., Inc, India Hemp Organics, Its Hemp, The Trost, and Gin Gin) involved in promoting the Indian hemp
products, marketing, R & D research, cultivation, harvesting, processing, manufacturing, trading, wholesaling, retailing, innovating, advocating and motivating
customers across India and around the world. This will help to boost the Indian economy and increase the productivity of the Indian hemp (fiber type).
Keywords: Ayurveda, Cannabis, Cannabinoids, Ethnomedicine, Folk medicine, Hemp, Phytomedicine, India, Industrial hemp (fiber type), Traditional medicine,
Δ9-tetrahydrocannabinol (THC).
INTRODUCTION
Ayurveda is a science of life with a holistic approach to
health and personalized medicine (1-9). It is one of the oldest Indian
medical systems, which comprises thousands of medical concepts
and hypothesis (1-9). Hemp was mentioned in Ayurveda, as one of
the medicinal plant used for many diseases (1-9). Ayurveda, the
traditional Indian medicinal system remains the most ancient yet living
traditions with sound philosophical and experimental basis (1-9).
Ayurveda is an age-old practice of medical treatment meaning The
Science of Life”. The history of Ayurveda goes deep in the Indian
roots. It was developed more than 5,000 years ago in India (1-9).
Ayurveda is a contemporary and alternate form of medicine (1-9).
According to the World Health Organization, about 70–80% of the
world populations rely on nonconventional medicines mainly of herbal
sources in their healthcare (1-9). Public interest for the treatment with
complementary and alternative medicine is mainly due to increased
side effects in synthetic drugs, lack of curative treatment for several
chronic diseases (1-9; 82-85).
Ayurveda is based on a conceptual medical system that
seeks to balance three functional elements, called doshas, that the
human body is composed of, and are commonly represented as Vata
or Vayu (ether or air), Pitta (fire and water) and Kapha (phlegm or
water and earth) (1-9). India is a land steeped in faith and mysticism
(1-9). Interestingly, Ayurveda has the ability to treat many chronic
diseases such as cancer, diabetes, arthritis, and asthma, which are
untreatable in modern medicine (1-9). Unfortunately, due to lack of
scientific validation in various concepts, this precious gift from our
ancestors is trailing (1-9).
*Corresponding Author: Ravindra B. Malabadi,
1Department of Applied Botany, Mangalore University, Mangalagangotri-574199,
Mangalore, Karnataka State, India.
INDUSTRIAL HEMP (FIBER TYPE) HEMP: IMPORTANCE
Figure-1: Industrial hemp (fiber type), Cannabis sativa
Figure-2: Industrial hemp (fiber type), Cannabis sativa in the field.
Figure-3: The robust growth of Industrial hemp
(fiber type or grain type).
Industrial hemp (fiber type), Cannabis sativa (Figure-1, 2,
3) belongs to the family, Cannabaceae is considered as one of the
oldest plants of Asian origin particularly from India cultivated to
provide nutritional and medicinal benefits (10-71; 84-85). Cannabis
sativa L. is one of the medicinal plant known for fibre, medicinal,
psychoactive agents and oil. Industrial hemp (Cannabis sativa L.) is
an emerging food and fibre crop (10-70). It is a non-drug variety of
Cannabis sativa with low Δ9-tetrahydrocannabinol (THC) content of
less than 0.3 per cent (10-71) (10-82). Industrial hemp (Cannabis
sativa L.) with proven applications, ranging from the textile,
construction paper industries, nutritional, pharmaceutical and
cosmetic industries (10-70). Cannabis was similarly bound to faith
and mysticism in India in the past, in the Hindu and Islamic traditions,
as well as in numerous other minority religions (10-70). Ayurveda,
combining the Sanskrit words for life and knowledge, is a system of
medicine intertwined inextricably with these traits (1-10). More
prominently known as Vijaya in Ayurveda, medical cannabis has
been one of the hottest topics of discussion (1-9). Vijaya is used in
different Ayurvedic classical formulations. The formulations are
classical as they are mentioned in the Ayurvedic texts thousands of
years ago. Any other new formulations are patented and are known
as Proprietary products (1-85).
Industrial hemp (fiber type), Cannabis sativa (Figure-1, 2,
3) has been used by innumerable ethnic societies in Asia.
Uttaranchal (India) is an ethnic region where the plant is a part of the
local culture (8-29). The increased penetration of medical products in
the market is due to technology-based solutions. The goal is to build
a technology that reaches the right people with the correct
medication. The preparation of Ayurvedic formulations has to be as
per the rules and regulations of the legislation. Cannabis contains
different types of compounds i.e. cannabinoids, terpenoids,
flavonoids, etc. There are more than 113 types of cannabinoids
present in cannabis out of which CBD and THC have therapeutic
effects. Cannabis is defined as the Ayurvedic Drug – Bhang (except
seeds), Siddha Drug Ganja (except seeds), and Unani Drug
Bhang and Charas. Various studies are being conducted on medical
cannabis (1-78).
INDUSTRIAL HEMP (FIBER TYPE) HEMP : BOTANY
Industrial hemp (fiber type) (Figure-1, 2, 3) is a short-
day plant, which means it requires a long period of darkness to
form flowers (13-70, 82). Short-day plants develop flowers only
when the day length is less than about 12 hours. Its flowering is
delayed by long days and hastened by short days (82-85). Shorter
days then typically trigger flower development. Industrial hemp
(fiber type), is primarily dioecious, that is, the pollen-bearing parts
are found in one plant and the seed-bearing flowers on another (20-
67) (83). Cannabis has a diploid genome (2n = 20) (82). The male
and female plants are not distinguishable before flowering (20-50,
83). The male inflorescence can be identified by the development of
round, pointed flower buds with five radial segments, while the female
inflorescence can be identified by the presence of calyx (15-70, 82).
Male plants die shortly after flowering (82). The female plants live
3 to 5 weeks until seed is fully ripe (15-70, 82). In a dioecious crop,
the number of female plants is 10 per cent to 50 per cent higher than
the number of male plants (82). There are a few monoecious cultivars
that have both male and female flowers on the same plant (11-70, 82-
85).
The Narcotic Drugs and Psychotropic Substances Act,
1985 (NDPS, Act and the Drugs and Cosmetics Act, 1940),
Government of India, New Delhi, defines the scope of medicinal
cannabis. Under the Drugs and Cosmetics Act. The medicinal use of
cannabis has been recognized and falls under the “List of
poisonous substances under the Ayurvedic (including Siddha)
and Unani Systems of Medicine” in Schedule E1 of Drugs and
Cosmetics Rule, 1945.
CANNABIS SATIVA (HEMP) : FSSAI REGULATION
In 2017, the FSSAI (FOOD SAFETY AND STANDARDS
AUTHORITY OF INDIA), Government of India, New Delhi issued
notices to hemp manufacturers, highlighting that the sale of such
products under the FSSAI label is illegal. After, 4 years and a couple
of successful hemp businesses later, it has come around on 15th
November 2021 FSSAI, recognized hemp seed and hemp seed
products as food (10-29). The notification regulates and allows for
sale of products derived from 'non-viable seeds of the cannabis
sativa/other indigenous cannabis species' (10-29). And the cultivation
has to, as usual, comply with the NDPS and state laws (9-30).
Medical cannabis (marijuana type) and Industrial hemp
(fiber type) (Figure-1, 2, 3) are two varieties of the plant Cannabis
Sativa (1-80). Industrial hemp (fiber type) refers to the non-
intoxicating cannabis harvested for the industrial use of its products
(1-80). In Medical cannabis (marijuana type), tetrahydrocannabinol
or THC, the psychoactive compound that makes one feels “high,”
measures at about 17-30%, whereas Industrial hemp (fiber type)
has to contain less than 0.3% THC to be sold legally (1-80).
Industrial hemp (fiber type) is used in a variety of commercial and
industrial products in India: textiles, paper, bioplastics, building
materials, body care, and now Gin-Gin (Figure-1, 2, 3) (72-85).
CANNABIS SATIVA: MEDICINAL VALUE
According to Ayurveda Cannabis was extensively used to
treat a large kind of ailments such as sleep problems (insomnia,
induce sleep, soporific); Arthritis and pain (gout, rheumatism,
cancer, and arthritic pain); Gynecological disorders
(dysmenorrhea, menorrhagia, expedite delivery); Sexual
problems (erectile dysfunction, sex stimulation, low libido,
pleasant sensation); Gastrointestinal problems (diarrhea,
dyspepsia, strangulated hernia, poor digestion, dysentery);
Neuropsychiatric and CNS (paralysis, psychosis, insanity);
Infections and respiratory problems (tetanus, wound,
tuberculosis, cough, asthma); Cancer; and other ailments
including hypertension, headache, itch, increases bile secretion,
abortifacient, dandruff, fever, and urinary problems (1-85).
HEMP PRODUCTS: INDIAN START UP BIOTECH
COMPANIES
Following is the list of Indian companies (Bombay Hemp
Company, BOHECO, Satliva, Hemp Fabric Lab, Vedi, Happy
Hemp, SUI, ItsHemp, Bhu: Sattva’s, Health Horizons, Hemis, Hemp
International Journal of Innovation Scientific Research and Review, Vol. 05, Issue 02, pp.4040-4046 February 2023 4041
Republic, Hempsters, B.E. Hemp, India Hemp Co., Inc, India Hemp
Organics, ItsHemp, Health Horizons, Hemis, TheTrost,and Gin Gin)
involved in promoting the Indian hemp products marketing,
research, cultivation, harvesting, processing, manufacturing, trading,
wholesaling, retailing, innovating, advocating both across the nation
and around the world.
1. Bombay Hemp Company
Bombay Hemp Company is widely known as BOHECO’,
has partnered with The Hemp Factory, India’s first hemp-based cloud
kitchen (72-80). With BOHECO as collaborators, this vision to get
India to use hemp and its products to its full potential feels more
realistic than ever. Bombay Hemp Company, also popularly known
as BOHECO (Bo-hee-ko) is a privately held, social enterprise
headquartered in Mumbai, India. BOHECO was founded to research
on and promote industrial hemp, the super crop of our era in India.
BOHECO was formally registered under The Companies Act (1956)
on the 19th of January, 2013, with the operations ranging from
research, cultivation, harvesting, processing, manufacturing, trading,
wholesaling, retailing, innovating, advocating, creating a market for
and promoting Indian industrial hemp both across the nation and
around the world (72-80). BOHECO use public-private partnership,
contractual farming and processing, subsidiaries and collaborative
research models, all with an aim to build an industrial hemp
ecosystem or industry in India. The establishment includes the
superfood, and hemp in dishes made for everyone. Removing the
notion of hemp being included only in typically healthy meals, The
Hemp Factory caters to various kinds of foods. The aim of this cloud
kitchen is not to solely produce hemp-infused foods, but also to
further raise awareness about how hemp can help with several
ailments –– if not as a cure, but for management and on the journey
to better overall health. Located at Unit #2, Cama Industrial Estate,
Sun Mills Compound Rd, Lower Parel, Mumbai, Maharashtra
400013, India. Further, BOHECO CANNABIS HEALTH &
WELLNESS CENTER 295, 100 Feet Road, Next to Glen's
Bakehouse, HAL, 2nd Stage, Stage 3, Indiranagar, Bengaluru,
Karnataka - 560038.
2. Hemp Fabric Lab
The ready-made clothes are always a more convenient
option. Hemp Fabric Lab is a brainchild of BOHECO (Bombay Hemp
Company). So for those who like complete control of the kind of
clothes they wear, Hemp Fabric Label, an initiative of BOHECO, is an
online store for sustainable fabrics made from hemp. BOHECO is an
agro-based enterprise re-imagining the future of Indian agriculture
and sustainable living with hemp as its lens (72-80). The goal is to
educate and advocate for industrial hemp, promote its benefits to
society and assist local farmers in cultivating the crop by providing the
best seeds and practices in cultivation techniques for poverty
alleviation and rural development (72-80). Their fabrics come in a
variety of colours, specific for different applications. Furthermore, also
choose the type of fabric of interest - handloom, knit, or woven. With
hemp at the core of its production process, Hemp Fabric Label’s
offerings are vast and can be suited to fit current market needs (72-
80). The Hemp Fabric Lab are dedicated to providing 100% hemp
fabric and blends with other sustainable fibers like organic
cotton, Tencel, wool, silk, yak hair, nettle, Bamboo, Lyocell (72-80).
Hemp Fabric Lab is located at Unit #2, Cama Industrial Estate, Sun
Mills Compound Rd, Lower Parel, Mumbai, Maharashtra 400013
India (72-80).
Cannabis as a plant, and its flowers and buds (popularly
known as ‘Ganja’) are regulated as a “narcotic drug” under The
Narcotic Drugs and Psychotropic Substances Act, 1985 (NDPS Act),
but its leaves (popularly known as ‘Bhang’) seeds and fibres when
separated from the plant, or when separated, are not regulated as a
‘narcotic drug’ under NDPS Act (72-80). The fibre of the plant which
is used to make textiles is made from the stalk of the plant post
extracting the fibre through a technique called retting (72-80).
The provisions of the Act completely exempt the fibre and the uses of
the stalk and can be freely be used for textile applications. Therefore,
Hemp Fabric Lab are proud to announce that they have successfully
attained the permission to cultivate Industrial Hemp in India by
collaborating with the State Government of Uttarakhand (72-80). This
has enabled Hemp Fabric Lab to be one step closer to the 100%
Make in Indiainitiative by producing Hemp fabrics from fibre to
fabric (72-80).
3. Gin-Gin (Hemp-Gin)
Gin Gin is the newest spirit to join India’s
burgeoning Gin scene. Based in Goa, Khanna’s ingredients come
from across India, and amazingly and delivered via Amazon during
lockdown in India (72-80). Manufactured entirely in Goa, GinGin
sourced all its botanicals and ingredients locally from India. Made by
24-year-old Shubham Khanna, it took two years and 40 recipes to
get the product right, and ready to expand the marketplace (72-80).
Made up of nine unique botanicals, including hemp, Himalayan
juniper, coriander, lavender, rosemary, caraway seeds, cinnamon,
lemongrass, and butterfly pea flower, they have branded themselves
as India’s only single-shot distilled hemp Gin (72-80). In this
regard, adding hemp as a botanical would help pique a consumer’s
curiosity (72-80). Currently, Gin is thriving in India and the most
recently, Terai from Rajasthan. Gin Gin is also out of Goa, hit markets
across India (72-80). Gin Gin is a soft drink launched at a few bars
and hotels across Goa and is now hitting the market in India’s
sunshine state, Rajasthan (72-80). In a country populated by rum
and beer drinkers, Gin had always remained the dark horse (72-80).
Shubham Khanna’s GinGin entered the market with a characteristic
new to in the Indian space the addition of hemp. The addition of
hemp seeds themselves added a complex flavour. Gin Gin is also
India’s first, and currently only, hemp Gin.
The seeds are a part of the Industrial hemp (fiber type),
Cannabis Sativa plant that contains none too little
Tetrahydrocannabinol (THC), the substance that produces
psychoactive effects. GinGin would be able to provide with the mind-
altering feeling that Cannabis provides (72-80). In fact, it is high in
proteins, fibre and healthy fatty acids. Completely legal and approved
by authorities in India, hemp seeds are not different from chia seeds
(72-85).
4. Satliva
Satliva is a Bangalore, Karnataka, India -based hemp
shop boasts of the finest range of luxury chemical-free skin and
body care products (72-80). All their products are a combination of
hemp oil and other natural cold-pressed oils made freshly on order
(72-80). Satliva believes that Nature is the best Nurture and with
that, it brings sustainability home (72-80). A hemp shop based out of
Bengaluru, Satliva sources their raw material specially from the
foothills of Himalayas (72-80). The brand offers a range of the finest
chemical free products all made with a combination of hemp oil
and other natural cold pressed oils (72-80).
5. Vedi
Vedi works with the intersection between Ayurveda and
hemp. It calls hemp a ‘jewel in the court of Ayurveda’, and considers
the infusion of cannabis into Ayurveda quite essential (1-9; 10-80).
International Journal of Innovation Scientific Research and Review, Vol. 05, Issue 02, pp.4040-4046 February 2023 4042
Recognising the role that it has played in the historic practice of
Ayurveda, Vedi aims at using hemp to help India find its Ayurvedic
roots (1-80). Vedi Herbals is in the forefront of holistic healing and
Ayurvedic care (1-9; 72-80). The pioneer of cannabis medicines in
India, Vedi has brought the versatile healing properties of
Cannabidiol (CBD), oil to the people and has made natural
healthcare accessible (1-49). Vedi also makes hemp oil products for
hair and skin care, for a greener lifestyle. The journey of Vedi began
in 2016, when interacted with the tribal populace in Odisha while
travelling (72-80). Then wonderstruck by how farmers and their
families had beautifully internalized the principle of Ayurveda and
were living the ideal life (72-80). Vedi Herbals is a young and fast-
emerging enterprise for Herbal Healthcare and Body care
products, based in India (72-80).
6. Bhu: Sattva
A Gujarat-based organic clothing brand that makes use of
a variety of sustainable fibres including hemp (72-80). Bhu:Sattva’s
core philosophy works in the opposite direction as that of fast fashion.
Known for its vibrant colors that seem to be oozing out of nature’s
offerings like beetroots, pomegranate, tree leaves etc (72-80).
Bhu:Sattva’s designs are timeless and deeply rooted in the Indian
ethos. Known for its smart cuts, vibrant colours, and eclectic designs,
Bhu:Sattva is one of the few hemp-using organic brands in the
country that has been around for almost a decade (72-80).
7. B.E Hemp
Making ethically sourced hemp products available to all at
affordable prices at B.E Hemp. Furthermore B.E. Hemp covers all
bases when it comes to the hemp industry. B. E-Hemp sell products,
affiliate themselves with other brands, cater to wholesale needs and
also wish to push the hemp message by narrating their (and others’)
journey in the Cannabis domain (72-80). This Bengaluru,
Karnataka-based organisation’s original hemp products include All-
Natural Hemp Soap, All-Purpose Healing Salve and Unbleached
Hemp Paper (72-80). B. E-Hemp will also find stationery, wallets,
beanies and skincare products on their website (72-80). Bonus points
to B.E Hemp for their smart use of words such as ‘Add To Stash’ and
‘Blaze Through Our Shop’ which is a good wordplay when we see
one (72-80).
8. BOHECO
Perhaps one of the more well-known Hemp companies,
BOHECO has truly made its mark as a champion of sustainability in
the Indian market (72-80). The company assists local farmers in
cultivating the crop by providing optimum seeds and cultivation
techniques (72-80). From thereon, BOHECO ensures that it builds a
sustainable business model for economic, environmental and social
impact (72-80). In partnership with retreat Poonthottam
Ayurvedasram in Kerala, they provide Ayur-Cann therapies. One
should would book a stay immediately. Poonthottam Ayurvedasram
in Pallakad, Kerala is Asia’s first Ayurvedic-cannabis wellness
retreat (72-80). In partnership with the Bombay Hemp Company, this
holistic retreat focuses on Ayurvedic therapies, yoga, meditation,
diet plans, and more. Assisted by hemp or cannabis supplements (if
need), guests may be encouraged to incorporate all of this into their
daily lives after a consultation.
BOHECO, India’s premier Industrial Hemp & Medicinal
Cannabis Company, has constantly made efforts towards bringing
an assortment of haute couture sustainable organic fabrics, yarns and
blends to the Indian populace (72-80). BOHECO has a range of
apparel that all easily blend into the modern day aesthetic of
wardrobe (72-80).
9. The Trost
The Trost’ when translated to German refers to solace
(72-80). Their sun grown hemp is ethically sourced and comes in the
form of hemp hearts, oil, protein powder, and more. With a promise to
transport to a place of bliss, the Trost also gave India its first hemp
cigarettes (72-80).
10. Its Hemp
Its-Hemp has got it all apparel, food, accessories, gifts,
furnishing, and wellness products (72-80). Segregated under hemp,
cannabis, and Ayurvedic cannabis, one can pick products based on
their needs (72-80). They cater to friends parties
Its Hemp has got apparel food, accessories, gifts,
furnishing, wellness products. They even offer subscription-based
purchases of products such as oils and powders (72-80). Apart from
great products, Its Hemp can also educate themselves about the
Cannabis plant and hemp and where it stands in India. They even
have a Hemp Starter Kit for those who are just venturing into this
sphere (72-80). Its Hemp has Pet Products’ section that extends
hemp care to furry loved ones. The hemp used is harvested in the
Himalayas in the purest form. Its products range into skincare as well
as wellness (72-80).
11. India Hemp Organics
Rohit Kamath and Loveena Sirohi, the brains behind
India Hemp Organics where Cannabis is perceived and consumed
in the country. Medicinal products catering to pain relief, better
sleep, and reducing stress were marketed by India Hemp Organics
(72-80). India Hemp Organics also retailed hemp hearts, hemp
powder, and hemp seed oil. Industrial hemp (fiber type)- Cannabis
sativa is a sustainable, eco-friendly and multipurpose medicinal plant
and this variety is known for storehouse of protein, fibre and oil (13-
80). Hemp is an important super food that contains plant-based
proteins. They also has a great source of healthy fats and essential
amino acids (72-80). When consumed daily, they improved overall
cognitive and physical performance (10-80). They also contain
significant amounts of protein that aids with muscle-building as well
(72-80). Loveena Sirohi, Co-Founder and Director, India Hemp
Organics, who provide sustainably sourced, non-GMO, 100% plant-
based, and preservative-free hemp (72-80). However, the amount of
protein and healthy fats in the hemp hearts and protein powders can
cause digestive issues if consumed improperly. “To avoid any issues,
India Hemp Organics recommended eating 2 to 3 tablespoons of
either hemp hearts, hemp powder, or hemp seed oil a day. Just 3
tablespoons of any hemp product contains up to 9.5 g of protein
which is almost as much as a single egg (72-80). CannaBliss’, that
consists of Cannabis leaf oils used for several purposes
neurological problems, pain management, insomnia, side-effects of
chemotherapy apart from providing daily well-being.
12. India Hemp & Co.
Sisters Jayanti and Shalini Bhattacharya founded India
Hemp & Co. to bring together their passions of nature, health, art and
business (72-80). Apart from hemp products, the brand also gives
recipes for guidance about hemp products. A well-rounded approach
to integrating hemp in one’s daily lives. As seen on Shark Tank, the
brand’s courtesy also extends to dogs in the form of treats (72-80).
They offer Hemp Seed Trail Mix, Hemp Protein Powders, Hemp Seed
International Journal of Innovation Scientific Research and Review, Vol. 05, Issue 02, pp.4040-4046 February 2023 4043
Oil and more (72-80). They even have a hemp pack dedicated to
home chefs to help them add a new dimension in their dishes.
Additionally, they have a few hemp recipes up on their website as
well (72-80).
13. Hempsters
Specialising in body care, Hempsters aims at offering their
customers luxurious, natural and completely hand-made hemp
products. They make sure to ingrain organic and age-old recipes,
too. Hempsters is a perfect mixture of the natural aesthetic and
sustainable skin care. Their products are available on Amazon.
14. Hemp Republic
Having chosen to be a part of the nationwide hemp
revolution, Hemp Republic caters to a variety of consumers across
India. The company is based in Telangana and manufactures hemp
fabrics, paper, yarn, and more. All of their products are made in
India and Fairtrade certified among other accreditations.
15. Hemis
Hemis successfully ventures into lifestyle products such as
apparel, accessories, furnishing, footwear and stationery. Their
products use raw materials that are ‘responsibly sourced, earth-
friendly and completely organic. Not only does Hemis provide
guaranteed quality, but it also does not compromise on the design
and style in any way.
16. Health Horizons
Health Horizons will provide a superfood in diet and
improve overall well-being with hemp as food. Additionally, the
Health Horizons also provides delicious recipes using hemp
products and hemp information (72-80). Apart from Hemp Sativa
Nubs, Hemp powder and Hemp sativa oil in their armoury, and the
company also offers personal care products such as Lavender &
Hemp Face Cream, Aloe Vera & Hemp Body Butter and cold pressed
Hemp Oil (72-80). Health Horizons not only market quality hemp
products, but also important to educate its customer through its
‘Hemp Updates’ and ‘Hemp In The Media’ sections. (72-80).
17. SUI
Hemp being their Star Fabric’ is an integral element of
most of SUI designs and helped to ensure that every new collection
has a unique ‘green’ heart (72-80). SUI's latest collection is inspired
not just by the raw beauty and cool coast of California. In addition
also by the importance of long-term survival of such natural beauty
which is only possible in a world where production is inherently
responsible.
18. Happie Hemp
Happie Hemp, a biotechnology company is developing
Ayurvedic products derived from Cannabis leaf and Hemp leaves (1-
80). Entrepreneurs today are focusing on maximizing the efficacies of
Ayurveda (1-78). Enthusiasts are coming forward to expand the
tremendous potential of medical cannabis (10-80).
CONCLUSION
Industrial hemp (fiber type) is a crop with multiple uses
(Figure-1, 2, 3). Its exceptional functional properties, rapid
renewability and low environmental footprint are driving a number of
markets with strong growth potential. In comparison with other bast
fibres (such as from flax, kenaf, jute or ramie), hemp fibre has
excellent fibre length, strength, durability, absorbency, anti-mildew
and anti-microbial properties. Hemp offers super absorbency. This
quality is desirable for oil and gas cleanup, livestock bedding and
personal hygiene markets. Hemp is very high in tensile strength,
strength-to-weight ratio, flexural strength and ability to rebound are
desired benefits in bio-composites for automotive parts, aerospace
and packaging. The textile, paper and building markets have interest
in some specialty applications due to hemp’s durability, anti-microbial,
acoustic and aesthetic properties. There are many Indian companies
(Bombay Hemp Company, BOHECO, Satliva, Hemp Fabric Lab,
Vedi, Happy Hemp, SUI, ItsHemp, Bhu:Sattva’s, Health Horizons,
Hemis, Hemp Republic, Hempsters, B.E. Hemp, India Hemp Co., Inc,
India Hemp Organics, ItsHemp, Health Horizons, Hemis,
TheTrost,and Gin Gin) operations ranging from research, cultivation,
harvesting, processing, manufacturing, trading, wholesaling, retailing,
innovating, advocating, creating a market for and promoting Indian
industrial hemp both across the nation and around the world. This will
boost Indian economy and also hemp products in the market.
Today, the cost of health care is constantly rising, and
affecting people’s ability to afford health coverage. Drug-based
medicines are being unaffordable for economically poor countries like
India and problematic in the Western countries due to numerous side
effects. The drug should be the last rather than first mean of
treatment, beginning with the natural healing method like Ayurveda.
One of the Ayurvedic treatment modalities such as Panchkarma can
remove disease before its manifestation. Having all the above
beauties, Ayurveda is still lagging behind because of the lack of
scientific evidence in many cases and poor research methodology.
There is a ray of hope that in near future, hemp based healthcare
products will be in the market and customer demand for hemp
products is increasing. It is also a need to perform more biological
evaluation towards establishing therapeutic guidelines of Cannabis
and Cannabinoids and to provide a strengthened pharmacological
perspective about the prospects and challenges of Cannabis use in
the future.
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... In agriculture, hemp straw is utilized as fodder because of the high nutritional value it provides for livestock, especially cattle (Wang et al., 2023). Industrial hemp is of interest to a variety of businesses due to the vast ecological potential associated with the Cannabis plant and the variety of raw materials it can offer (Malabadi et al., 2023). Figure 9 exhibits some of the possible applications of the Cannabis plant. ...
... The entire food sector, notably organic food, presents a strong rivalry for hemp-based food products. Incorporating hemp-based foods into diet is good for health (Malabadi et al., 2023). They influence cell regeneration, aging processes, cancer cell development inhibition, and immunity significantly (Fike, 2016;Sheik et al., 2023). ...
... Many companies now make cosmetics like lotions, oils, soaps, shampoos, and conditioners that contain hemp oil (Sarkar & Sadhukhan, 2023). The CBD and resin portions of hemp extract are responsible for the sedative and relaxing effects (Malabadi et al., 2023). Hemp compounds are gaining popularity in the pharmaceutical and medical industries as well. ...
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... Cannabis sativa L. belongs to the family Cannabiaceae was used as a medicine before the Christian era in Asia, mainly in India, China, Bhutan, Nepal, Afghanistan, Pakistan and Iran, and Persians [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. Cannabis has been used for thousands of years for recreational, medicinal, or religious purposes . ...
... Cannabis is also a wild noxious weed with notorious psychoactive principle (THC) found growing in all the parts of India. Cannabis has a long history in India, recorded in legends and religion [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. It was found in various habitats ranging from sea level to the temperate and alpine foothills of the Indian Himalaya Region from where it was probably spread over the last 10,000 years [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. ...
... Cannabis has a long history in India, recorded in legends and religion [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. It was found in various habitats ranging from sea level to the temperate and alpine foothills of the Indian Himalaya Region from where it was probably spread over the last 10,000 years [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. Many historians believed that Indian Himalayan Region was the centre of origin of Cannabis sativa L. and Cannabis indica L. . ...
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This paper reviewed the importance of Cannabis sativa and highlights difference between Medical Cannabis (Marijuana or drug type) and Industrial hemp. Cannabis has been used for thousands of years for recreational, medicinal, or religious purposes. Industrial hemp and marijuana share the same species, Cannabis sativa L, but represent different varieties. As such, there are genetic differences that lead to different chemical characteristics, which, in turn, lead to different uses. Cannabis sativa L., is classified into two types as Industrial Cannabis sativa, hemp or Medical Cannabis sativa L.(drug or marijuana) based on its Λ9-tetrahydrocannabinol (THC), content. Medical Cannabis sativa (drug or marijuana) contains very high levels of Λ9-tetrahydrocannabinol (THC) (above 0.3 to 38% of dry weight) and grown inside the greenhouse controlled conditions for the production of unfertilized female flowers. These female flowers accumulates the psychoactive molecule THC and used for health disorders. On the other hand Industrial Cannabis sativaL. (Hemp) contains very low levels of THC (0 to 0.3% of dry weight) grown outside in a large agriculture farms for the production of fibre, seeds and oil. Hemp is used as a functional food and medicine since it contains Cannabidol (CBD), and very low levels of THC.
... Cannabis sativa L. belongs to the family Cannabiaceae was used as a medicine before the Christian era in Asia, mainly in India, China, Bhutan, Nepal, Afghanistan, Pakistan and Iran, and Persians [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. Cannabis has been used for thousands of years for recreational, medicinal, or religious purposes . ...
... Cannabis is also a wild noxious weed with notorious psychoactive principle (THC) found growing in all the parts of India. Cannabis has a long history in India, recorded in legends and religion [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. It was found in various habitats ranging from sea level to the temperate and alpine foothills of the Indian Himalaya Region from where it was probably spread over the last 10,000 years [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. ...
... Cannabis has a long history in India, recorded in legends and religion [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. It was found in various habitats ranging from sea level to the temperate and alpine foothills of the Indian Himalaya Region from where it was probably spread over the last 10,000 years [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. Many historians believed that Indian Himalayan Region was the centre of origin of Cannabis sativa L. and Cannabis indica L. . ...
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This paper reviewed the importance of Cannabis sativa and highlights difference between Medical Cannabis (Marijuana or drug type) and Industrial hemp. Cannabis has been used for thousands of years for recreational, medicinal, or religious purposes. Industrial hemp and marijuana share the same species, Cannabis sativa L, but represent different varieties. As such, there are genetic differences that lead to different chemical characteristics, which, in turn, lead to different uses. Cannabis sativa L., is classified into two types as Industrial Cannabis sativa, hemp or Medical Cannabis sativa L.(drug or marijuana) based on its Λ9-tetrahydrocannabinol (THC), content. Medical Cannabis sativa (drug or marijuana) contains very high levels of Λ9-tetrahydrocannabinol (THC) (above 0.3 to 38% of dry weight) and grown inside the greenhouse controlled conditions for the production of unfertilized female flowers. These female flowers accumulates the psychoactive molecule THC and used for health disorders. On the other hand Industrial Cannabis sativaL. (Hemp) contains very low levels of THC (0 to 0.3% of dry weight) grown outside in a large agriculture farms for the production of fibre, seeds and oil. Hemp is used as a functional food and medicine since it contains Cannabidol (CBD), and very low levels of THC.
... Cannabis sativa L. belongs to the family Cannabiaceae was used as a medicine before the Christian era in Asia, mainly in India, China, Bhutan, Nepal, Afghanistan, Pakistan and Iran, and Persians [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. Cannabis has been used for thousands of years for recreational, medicinal, or religious purposes . ...
... Cannabis is also a wild noxious weed with notorious psychoactive principle (THC) found growing in all the parts of India. Cannabis has a long history in India, recorded in legends and religion [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. It was found in various habitats ranging from sea level to the temperate and alpine foothills of the Indian Himalaya Region from where it was probably spread over the last 10,000 years [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. ...
... Cannabis has a long history in India, recorded in legends and religion [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. It was found in various habitats ranging from sea level to the temperate and alpine foothills of the Indian Himalaya Region from where it was probably spread over the last 10,000 years [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. Many historians believed that Indian Himalayan Region was the centre of origin of Cannabis sativa L. and Cannabis indica L. . ...
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This paper reviewed the importance of Cannabis sativa and highlights difference between Medical Cannabis (Maijuana or drug type) and Industrial hemp. Cannabis has been used for thousands of years for recreational, medicinal, or religious purposes. Industrial hemp and marijuana share the same species, Cannabis sativa L, but represent different varieties. As such, there are genetic differences that lead to different chemical characteristics, which, in turn, lead to different uses. Cannabis sativa L., is classified into two types as Industrial Cannabis sativa, hemp or Medical Cannabis sativa L.(drug or marijuana) based on its Λ9-tetrahydrocannabinol (THC), content. Medical Cannabis sativa (drug or marijuana) contains very high levels of Λ9-tetrahydrocannabinol (THC) (above 0.3 to 38% of dry weight) and grown inside the greenhouse controlled conditions for the production of unfertilized female flowers. These female flowers accumulates the psychoactive molecule THC and used for health disorders. On the other hand Industrial Cannabis sativa L. (Hemp) contains very low levels of THC (0 to 0.3% of dry weight) grown outside in a large agriculture farms for the production of fibre, seeds and oil. Hemp is used as a functional food and medicine since it contains Cannabidol (CBD), and very low levels of THC.
... Each production environment faces challenges from plant pathogens, with indoor and greenhouse systems sharing more diseases in common compared to field-grown Cannabis . In India, organic farming of hemp has been developed and hemp is successfully cultivated in a large agriculture farms (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18). Cultivation of hemp occurs mostly outdoors, with plants initiated directly from seed or occasionally from transplanting of rooted cuttings produced in greenhouses (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19). ...
... In India, organic farming of hemp has been developed and hemp is successfully cultivated in a large agriculture farms (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18). Cultivation of hemp occurs mostly outdoors, with plants initiated directly from seed or occasionally from transplanting of rooted cuttings produced in greenhouses (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19). The major challenges facing expanding cultivation of hemp are seed quality and pressure from weeds, insects and diseases . ...
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This review paper highlights the fungal diseases of both indoor and outdoor Cannabis cultivation environments and discusses the Artificial intelligence (AI) based crop disease detection and management. Pathogens are a pain in the neck of every Cannabis breeder. They affect the quality and quantity of yield, thus defeating the aim of cultivation. Some of the fungal pathogen that can attack Cannabis crops are Botrytis, Alternaria, Fusarium, Penicillium, Cladosporium, and Aspergillus. Fungal diseases are Powdery Mildew, Damping off, and Mildew. Of these fungal pathogens, the most common inflorescence disease is gray mold, caused by Botrytis cinerea. Botrytis cinerea and Erysiphe species complex are currently the most widespread pathogens of Cannabis worldwide. The greatest challenge facing Cannabis and hemp producers is the management of insect pests and pathogens that attack the roots, leaves and inflorescences. The common disease management strategies are-remove and destroy infected plants. Irradiate dried buds with gamma or electro-beam radiation. Another method is to apply biological control agents at rooting and vegetative stages of growth. Pesticides have been found in all Cannabis products, from flowers to edibles, vapes, and smokes. The pesticide pandemic in the Cannabis industry needs urgent attention. Cannabis can contain fungal pathogens and residues of pesticides, fungicides that cause serious and often fatal infections in persons with immunocompromised conditions, such as cancer, transplant, or infection with HIV. Contamination of Cannabis plants and products (i.e., recreational-and pharmaceutical-grades) with mycotoxigenic organisms, including species of Aspergillus, Penicillium, and Fusarium, pose serious health challenges. The manual Cannabis disease identification process is time-consuming and tedious work. Instead, automated methods save both time and effort. The technology of Artificial Intelligence (AI) in the detection and management of disease has already been employed in many crops. The machine learning (ML)-based models were proposed for the identification and classification of plant diseases. The PlantVillage dataset is the largest and most studied plant disease dataset, which is used as a reference for the disease detection and management of plant diseases.
... It can replenish the soil by killing and displacing other tiny crops or weeds [1] and absorbing heavy metals from soils [1,. Hemp can be used for insulation and acoustic purpose in the building sector, paper industry [1], medicinal purpose, textile industry [1], biofuel, cosmetics industry [1], food and beverage industry [23], and fibre can be used as reinforcement in polymer matrix composites [1] or in bio-composite as a substitute of glass and carbon fibre [1,. ...
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This review paper updates the benefits of using hemp fibre for the production hemp plastic. Traditional fossil-fuel based plastic production emits massive levels of greenhouse gasses, and the material can take hundreds of years to break down. Traditionally, plastics are made from petroleum-based compounds, which release toxic gases into the atmosphere. Petroleum-based plastics and its by-product have a devastating effect on the land, water, and wildlife.
... It can replenish the soil by killing and displacing other tiny crops or weeds [1] and absorbing heavy metals from soils [1,. Hemp can be used for insulation and acoustic purpose in the building sector, paper industry [1], medicinal purpose, textile industry [1], biofuel, cosmetics industry [1], food and beverage industry [23], and fibre can be used as reinforcement in polymer matrix composites [1] or in bio-composite as a substitute of glass and carbon fibre [1,. ...
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This review paper updates the benefits of using hemp fibre for the production hemp plastic. Traditional fossil-fuel based plastic production emits massive levels of greenhouse gasses, and the material can take hundreds of years to break down. Traditionally, plastics are made from petroleum-based compounds, which release toxic gases into the atmosphere. Petroleum-based plastics and its by-product have a devastating effect on the land, water, and wildlife. Biodegradable plastics are produced using petro-chemicals just like conventional plastics except some additives are included in their manufacturing which helps them in there fast degradation. Hemp plastic is a type of biodegradable plastic made from hemp fibres, which has a sufficiently high cellulose concentration in manufacturing polymers. The resulting material is fully biodegradable and recyclable. It can then be processed into various products, including packaging, consumer goods, automotive parts, and more conventional plastics. Hemp plastic which is 100% biodegradable, can be a better alternative to synthetic plastic. Hemp plastic is also lightweight, with an impressively high density to weight ratio. This makes hemp plastic a potentially good material for making lightweight components in the car and aerospace industry. Conversely, hemp plastic helps to minimize the greenhouse effect. Hemp plastic offers great thermal, UV, and dimensional stability. Some types of hemp plastic are also resistant to flame. Hemp plastic is solely produced using the cellulose extracted from hemp plant and therefore, causes no toxicity during its production.
... It can replenish the soil by killing and displacing other tiny crops or weeds [1] and absorbing heavy metals from soils [1,. Hemp can be used for insulation and acoustic purpose in the building sector, paper industry [1], medicinal purpose, textile industry [1], biofuel, cosmetics industry [1], food and beverage industry [23], and fibre can be used as reinforcement in polymer matrix composites [1] or in bio-composite as a substitute of glass and carbon fibre [1,. ...
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This review paper updates the benefits of using hemp fibre for the production hemp plastic. Traditional fossil-fuel based plastic production emits massive levels of greenhouse gasses, and the material can take hundreds of years to break down. Traditionally, plastics are made from petroleum-based compounds, which release toxic gases into the atmosphere. Petroleum-based plastics and its by-product have a devastating effect on the land, water, and wildlife.
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Global warming, climate change, local air pollution, ozone depletion, acid rain and depletion of fossil fuel are the major global environmental issues. Presently, non-renewable fossil fuels meet up to 80% of the world's energy demand. Rapid consumption of fossil fuels as well as rising environmental pollution caused by extreme CO2 emissions, sulphur dioxide, and aromatic hydrocarbons has become crucial in searching for a clean and renewable energy source such as biodiesel. With continuous growth in the world's population, rapid industrialization, urbanization, and economic growth, fossil fuel consumption is escalating to meet the global energy demand. Biodiesel is renewable, non-toxic, environment-friendly and an economically feasible options to tackle the depleting fossil fuels and its negative environmental impact. Biodiesel is an alternative fuel made by transesterification reaction of oil and alcohol under the influence of catalyst. Biodiesel is an alcoholic ester of various fatty acids, also known as FAME (Fatty Acid Methyl Esters). In the process of transesterification, the performance of the catalyst is the key factor of the biodiesel yield. Catalysts used in biodiesel production are classified as homogeneous, heterogeneous, and enzymatic catalysts. The incorporation of a catalysis-based transesterification reaction generally increases the rate of reaction and enhances the yield of the end product. In case of homogeneous catalysts, there are problems of catalyst poisoning and contamination. Heterogeneous acid catalysis has a lesser toxic effect and gives rise to fewer environmental problems compared to the homogeneous mode. The cost of each specific catalyst depends on various factors, including the source, synthesis method, and its reusability. Generally, using waste or biomass as sources of catalysts may reduce the price of commercially available solid catalysts.
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This review paper highlights the importance and role of hemp fibre in textile industries. In recent years, there has been a resurgence of interest in hemp as a sustainable and versatile textile fibre in fashion and textile industry. Hemp is a sustainable and environmental friendly crop that can provide valuable raw materials to a large number of industrial applications. Hemp fibre is very strong compared with other natural fibres such as cotton, flax and nettle. The cultivation of hemp has significantly less environmental impact compared to cotton. The industrial hemp contains primary and secondary fibres of which the primary fibres are utilisable for the textile end use. Hemp has been the mostly blended with cotton and synthetic fibres due to barriers in the industrial process of the production of full hemp-based textiles. Hemp clothing is stronger and more durable than cotton clothing and does not deform as easily. Apparel made from hemp merges easily with dyes and does not discolour easily. Hemp has outstanding antibacterial properties that surpass those of cotton and also any other natural fibre. Hemp textile fibre is hypoallergenic and has natural antimicrobial properties, making it an excellent choice for individuals with sensitive skin. However, despite its many benefits, hemp is still relatively expensive in India compared to other cellulosic fibres such as cotton, linen, and rayon etc. Hemp has a great cultural and historical value in India because it has been grown and used here for thousands of years. This cultural history can be conserved and honoured by using hemp in the fashion and textile business.
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This literature review paper highlights the importance of female inflorescence of Cannabis sativa (medical cannabis; marijuana type or drug type). The inflorescence was used, traditionally, for acute pain, insomnia, coughing, and wounds. Cannabidiol (CBD) could be used as an anti-viral agent or anti-inflammatory tool, or to inhibit pulmonary fibrosis in COVID-19 patients. The female inflorescence is the main product of medical cannabis (marijuana type). The Cannabis inflorescence can be defined as a highly branched compound racemose. Δ9-tetrahydrocannabinol (THC) is the major psychoactive component and the toxicity of this metabolite of Cannabis is the most studied. Sales and cultivation of Medical Cannabis (marijuana type) is banned in India as an illicit drug and are illegal in India. One plant, Cannabis sativa with two names; Medical cannabis sativa (marijuana type), and second one is Industrial Cannabis sativa (fiber type). Furthermore, pollination is a process by which plants increase the genetic diversity within the species. The most common stressors impacting cannabinoid production are light, nutrition, predation, temperature, and water deficit. Industrial Hemp (fiber-type) is both an agricultural and industrial commodity and stem supplies both cellulosic and woody fibers. Hempcrete is a building construction material made from hemp fibres, lime and water. This composite, hempcrete breathes, as well as having good thermal and acoustic-insulation properties. However, hempcrete does have several key drawbacks that make it less than ideal as a building material. In addition to poor mechanical performance, hempcrete also has a high capacity to absorb and retain water. Therefore, future in detail study is warranted for the commercialization of hempcrete as a building material.
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This literature review paper is developed as a part of the awareness and to gather scientific information about the medicinal plant, Cannabis sativa. Several researches have shown the potential medicinal activity of Cannabis and its chemical compounds. Cannabis sativa L. is one of the medicinal plant known for fibre, medicinal, psychoactive agents and oil. There are two names of Cannabis sativa one is Medical cannabis sativa (marijuana type), and another one is known Industrial Cannabis sativa (fiber type).. There is still a huge prejudice in society in relation to Medical cannabis sativa (marijuana type) due to its recreational use. In India, Cannabis sativa is also commonly known as Indian hemp, marijuana, Bhang, Ganja, and Charas, which are banned in India as an illicit drug. Sales and cultivation of Medical cannabis (marijuana type) are illegal in India. However, this scenario is changing, and the social resistance is decreasing for the medicinal use of Cannabis. The plant derivatives were identified as psychoactive compound, Δ9-tetrahydrocannabinol (Δ9-THC or THC) and Cannabidiol (CBD), as well as, the endocannabinoid system, cannabinoid receptors type 1 and type 2 (CB1 and CB2, respectively). The plant has gained a lot of popularity in the last few decades for not only being an illicit drug but for its medicinal values from ancient times and a potential source for modern drugs to treat several targets for human wellness. Herein, our aim is to perform a literature overview about the plant, ethnobotany, and its chemical compounds of therapeutic interest.
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Indoor cannabis (Cannabis sativa) cultivation has been rapidly increasing in many countries after legalization. Besides conventional propagation through cuttings, synthetic seed production provides a competent system for mass propagation, germplasm conservation and international exchange of genetic materials. The present study developed a reliable protocol for cannabis synthetic seed production using encapsulation of nodal segments derived from in vitro or in vivo sources. Synthetic seeds were produced in 3% sodium alginate and 75 mM calcium chloride in Murashige and Skoog (MS) medium and stored under various environmental conditions for up to 150 days. The plantlets regrowth efficiency was monitored on culture media up to 30 days after the storage period. Regrowth rates of 70% and 90% were observed in synthetic seeds from in vitro and in vivo-derived sources, respectively, when stored in 6 °C under 50 μmol s−1 m−2 light for 150 days. Furthermore, addition of acetylsalicylic acid (ASA) to the encapsulation matrix not only postponed precocious germination of synthetic seeds at 22 °C, but also improved the regrowth rate of in vivo-derived synthetic seeds to 100% when they were stored in 6 °C under light. Exposure to light during storage significantly increased shoot length of regrown synseeds when compared to those stored in darkness. This difference in shoot growth disappeared when synseeds were treated with 25 µM ASA. All regenerated plantlets were rooted and acclimatized in sterile rockwool plugs without morphological changes.
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Cannabis sativa L. is one of the oldest cultivated crops, used in medicine for millennia due to therapeutic characteristics of the phytocannabinoids it contains. Its medicinal properties are highly influenced by the chemotype, that is, the ratio of the two main cannabinoids cannabidiol (CBD) and Δ-9-tetrahydrocannabinol (THC). Based on published data, the chemotype should correlate with plant morphology, genetics, and photosynthetic properties. In this work, we investigated leaf morphology, plant growth characteristics, cannabinoid profiles, THCAS gene sequences, and plant photosynthetic traits in two breeding populations of medical cannabis (MX-CBD-11 and MX-CBD-707). The populations differed significantly in morphological traits. The MX-CBD-11 plants were taller, less branched, and their leaves had narrower leaflets than the bushier, wideleaved MX-CBD-707 plants, and there were significant differences between populations in the dry biomass of different plant parts. Based on these morphological differences, MX-CBD-11 was designated as a narrow leaflet drug type or vernacular “Sativa” type, while MX-CBD-707 was classified as wide leaflet drug type or “Indica” type. Chemical characterisation revealed a discrepancy between the expected chemotypes based on plant morphology; although both populations have high CBD, within each Type II (CBD/THC intermediate) and Type III (CBD dominant) plants were detected. The THCAS gene sequence analysis clustered the plants based on their chemotypes and showed high similarity to the THCAS sequences deposited in NCBI. In silico complementary analysis, using published molecular markers for chemotype determination, showed their low discrimination power in our two populations, demonstrating the genotype dependence of the molecular markers. Basic photosynthetic traits derived from light and CO 2 response curves were similar in the populations. However, measurements of gas exchange under chamber conditions revealed higher stomatal conductivity and photosynthesis in MX-CBD-707 plants, which were also characterised by higher day respiration. The results of this study showed that based on visual appearance and some morphological measurements, it is not possible to determine a plant’s chemotype. Visually homogenous plants had different cannabinoid profiles and, vice versa, morphologically distinct plants contained similar CBD and THC content. The two chemotypes identified in our experimental plants therefore did not correlate with plant visual appearance, leaf morphometry, and photosynthetic properties of the populations studied. Correlation was only demonstrated with the respect to THCAS sequences, which showed great discrimination power between the chemotypes.
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Cannabinoids are natural compounds found in the hemp (Cannabis sativa). Scientific interest in cannabinoids arose after the discovery of the major psychoactive component in hemp, Δ9-tetrahydrocannabinol. Subsequent studies detected receptors in the brain subject to the actions of this compound, along with ligands for these receptors, i.e., endogenous cannabinoids (EC), which make up, along with the enzymes synthesizing, transporting, and degrading them, the endocannabinoid system (ECS). Interest in EC has consistently increased in recent years, especially after their important role in cognitive functions was discovered. They are regulators of synaptic transmission in the brain, mediate numerous forms of plasticity, and control neuron energy metabolism. EC exert influences using a series of mechanisms and interactions with neuromediators, neurotrophic factors, and neuropeptides. The main functions of EC in the brain are retrograde synaptic signaling and neuromodulation, which maintain cellular homeostasis. Information on the influences of cannabinoid drugs on cognitive functions is very contradictory. The cause of this may be that there are still inadequate strictly scientific data from clinical and sociological studies, while in animal experiments different authors use different methods and approaches for actions on the ECS. Thus, effects can differ depending on the substances used, their doses, and routes of administration, and the tasks and experimental conditions selected for testing. There is an extensive literature on the protective effect of ECS activation in neurodegenerative diseases in humans and models of cognitive deficit in animals. This review addresses data providing evidence of the influences of cannabinoid drugs and activation of the EC system on cognitive functions in the normal brain and in neurodegenerative diseases, Alzheimer’s disease, and temporal epilepsy. The possible causes of contradictions in existing data are also discussed.
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Cannabis has been legalized for recreational use in several countries and medical use is authorized in an expanding list of countries; markets are growing internationally, causing an increase in demand for high quality products with well-defined properties. The key compounds of Cannabis plants are cannabinoids, which are produced by stalked glandular trichomes located on female flowers. These trichomes produce resin that contains cannabinoids, such as tetrahydrocannabinolic acid and cannabidiolic acid, and an array of other secondary metabolites of varying degrees of commercial interest. While growers tend to focus on improving whole flower yields, our understanding of the “goldmines” of the plant – the trichomes – is limited despite their being the true source of revenue for a multi-billion-dollar industry. This review aims to provide an overview of our current understanding of cannabis glandular trichomes and their metabolite products in order to identify current gaps in knowledge and to outline future research directions.
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Cannabis is an annual plant with a long history of use as food, feed, fiber, oil, medicine, and narcotics. Despite realizing its true value, it has not yet found its true place. Cannabis has had a long history with many ups and downs, and now it is our turn to promote it. Cannabis contains approximately 600 identified and many yet unidentified potentially useful compounds. Cannabinoids, phenolic compounds, terpenoids, and alkaloids are some of the secondary metabolites present in cannabis. However, among a plethora of unique chemical compounds found in this plant, the most important ones are phytocannabinoids (PCs). Over hundreds of 21-22-carbon compounds exclusively produce in cannabis glandular hairs through either polyketide and or deoxyxylulose phosphate/methylerythritol phosphate (DOXP/MEP) pathways. Trans-Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) are those that first come to mind while talking about cannabis. Nevertheless, despite the low concentration, cannabinol (CBN), cannabigerol (CBG), cannabichromene (CBC), tetrahydrocannabivarin (THCV), cannabidivarin (CBDV), cannabinodiol (CBND), and cannabinidiol (CBDL) may have potentially some medical effects. PCs and endocannabinoids (ECs) mediate their effects mainly through CB1 and CB2 receptors. Despite all concerns regarding cannabis, nobody can ignore the use of cannabinoids as promising tonic, analgesic, antipyretic, antiemetic, anti-inflammatory, anti-epileptic, anticancer agents, which are effective for pain relief, depression, anxiety, sleep disorders, nausea and vomiting, multiple sclerosis, cardiovascular disorders, and appetite stimulation. The scientific community and public society have now increasingly accepted cannabis specifically hemp as much more than a recreational drug. There are growing demands for cannabinoids, mainly CBD, with many diverse therapeutic and nutritional properties in veterinary or human medicine. The main objective of this review article is to historically summarize findings concerning cannabinoids, mainly THC and CBD, towards putting these valuable compounds into food, feed and health baskets and current and future trends in the consumption of products derived from cannabis.