ArticlePDF Available

effect of deep breathing relax technique on labor pain intensity in the active phase

Authors:
  • Universitas Ibrahimy

Abstract and Figures

Labor pain is a combination of physical pain due to myometrial contractions accompanied by stretching of the lower segment of the uterus fused with the psychological condition of the mother during labor. The purpose of this study was to determine the effect of deep breathing relax technique on labor pain intensity in the active phase. Quasi-experimental Research Design with pre and post test without control. The sample in this study were 16 people. Sampling with purposive sampling method. The results of the research distribution of respondents before Deep Breathing Relax was mostly felt severe pain and after being given Deep breathing relax treatment most respondents experienced moderate to mild pain with a paried t test value of P = 0.000 < ? 0.05 thus there is an effect of deep breathing relax technique on labor pain intensity in the active phase.
Content may be subject to copyright.
How to Cite
Muldaniyah, M., Wahyuni, I. S., Malinda, R., Susanti, N. Y., & Fitria, L. (2023). The effect of deep breathing relax
technique on labor pain intensity in the active phase. International Journal of Health & Medical Sciences, 6(1), 17-
22. https://doi.org/10.21744/ijhms.v6n1.2080
ISSN 2632-9433
Submitted: 09 November 2022|Revised: 18 December 2022| Accepted: 27 January 2023 17
The Effect of Deep Breathing Relax Technique on Labor Pain
Intensity in the Active Phase
Muldaniyah
Graha Edukasi College of Health Sciences, Makassar, South Sulawesi, Indonesia
Corresponding author email: niamilda33@gmail.com
Indah Sri Wahyuni
Politeknik Karya Husada, South Jakarta, DKI Jakarta, Indonesia
Email: indahsekali03@gmail.com
Risnati Malinda
Bustanul Ulum Langsa College of Health Sciences,Aceh, Indonesia
Email: linda.ristama@gmail.com
Neny Yuli Susanti
Universitas Ibrahimy Situbondo, East Java, Indonesia
Email: nenyyulisusanti@gmail.com
Lia Fitria
Universitas Ibrahimy Situbondo, East Java, Indonesia
Email: leeafitria@gmail.com
Abstract---Labor pain is a combination of physical pain due to myometrial contractions accompanied by stretching
of the lower segment of the uterus fused with the psychological condition of the mother during labor. The purpose of
this study was to determine the effect of deep breathing relax technique on labor pain intensity in the active phase.
Quasi-experimental Research Design with pre and post test without control. The sample in this study were 16 people.
Sampling with purposive sampling method. The results of the research distribution of respondents before Deep
Breathing Relax was mostly felt severe pain and after being given Deep breathing relax treatment most respondents
experienced moderate to mild pain with a paried t test value of P = 0.000 < α 0.05 thus there is an effect of deep
breathing relax technique on labor pain intensity in the active phase.
Keywords---active phase, deep breathing relax, labor pain, laboring mothers, quasi-experimental research.
Introduction
Labor care aims to strive for survival and achieve a high degree of health for mothers and their babies. The main
focus of normal labor care is to prevent complications during labor to reduce maternal morbidity and mortality. One
of the indicators in determining the health status of a nation is characterized by high maternal and infant mortality
rates. Maternal mortality is still a very important reproductive health problem in Indonesia (Anissa et al., 2017).
According to the World Organization (WHO) in 2018, the number of deliveries reached approximately 108 per
100,000 live births and complications reached 50.3 per 100,000 live births (Ministry of Health, 2018). Some
countries have high maternal mortality rates such as Sub-Saharan Africa 179,000, South Asia 69,000, and Southeast
Asia 16,000. Maternal mortality rates in Southeast Asian countries where Indonesia is 190 per 100,000 live births,
18
Vietnam 49 per 100,000 live births, Thailand 26 per 100,000 live births, Brunei 27 per 100,000 live births, and
Malaysia 29 per 100,000 live births (WHO, 2020).
In South Sulawesi the number of maternal deaths reported by the District/ City Health Office has increased and
decreased, in 2021 the number of maternal deaths was 160 people or 110.26 per 100,000 live births, while in 2020 it
decreased to 115 people or 78.38 per 100,000 live births, in 2019 it increased again to 138 people or 93.20 per
100,000 live births. The main causes of maternal death are bleeding, infection, hypertension, preeclampsia-
eclampsia, abortion, and prolonged partus (South Sulawesi Health Profile, 2021). Labor pain is a combination of
physical pain due to myometrial contractions accompanied by stretching of the lower segment of the uterus together
with the psychological condition of the mother during labor. The anxiety of the mother's worries all merge so that
they can aggravate the physical pain that already exists. The perception of increasingly intense pain increases
maternal anxiety so that a cycle of fear, pain stress and so on occurs. Pain is an unpleasant and complex condition
that is an individualized phenomenon that is emotional in nature. Mothers feel worried about the pain that will be
faced during labor and birth and how the mother will react to pain and to overcome the pain (Indrayani & Djami,
2016).
Biswan et al. (2017) said that efforts to reduce pain during labor are carried out pharmacologically and non-
pharmacologically. Pharmacological pain management is more effective than non-pharmacological methods, but
pharmacological methods are more expensive and have the potential to have unfavorable effects, both for the mother
and the fetus. Meanwhile, non-pharmacological methods are cheaper, simpler, effective and without adverse effects
and can increase satisfaction during labor because the mother can control her feelings and strength (Fitri et al., 2019).
Deep breathing relaxation is one of the relaxation techniques that is often used to reduce pain and reduce pain
intensity by stimulating the central nervous system, namely the brain and spine to produce endrophins that function
as pain inhibitors. According to Andriana, the deep breath relaxation technique is a form of nursing care, in which
case the midwife teaches the client how to perform deep breathing techniques during contractions by using chest
breathing through the nose will flow oxygen to the blood, then flow throughout the body. So that the laboring mother
will feel relaxed and comfortable because the body will flow the endorphin hormone which is a natural pain reliever
in the body (Budiana, 2021).
Research by Fitri et al. (2019) entitled the relationship of deep breathing techniques to reducing active phase pain
intensity shows that the intensity of labor pain before treatment is 5.40 and after treatment is 4.07. The visible
difference value is 1.33 with a standard deviation of 1.163. The statistical test results obtained a p value of 0.000
<0.05, so Ho is rejected, which means that there is an effect of relaxation techniques on labor pain during phase I
with a p value of 0.000 (p value <0.05) (Astuti & Bangsawan, 2019). Based on this, the authors are interested in
conducting research on the effect of deep breathing relax techniques on the intensity of labor pain during the active
phase at Batara siang Pangkep Hospital (Alwan & Mohsen, 2022; Wahyuni & Maghfiroh, 2022).
Research Method
This study is a Quasi experiment using the one group pretest-postest type which aims to determine the effect of Deep
Breathing Relax on Labor Pain Intensity in the Active Phase. This study uses a Quasi-experimental research design
with pre and post test without control, which means that researchers only intervene in one group without comparison.
The effect of treatment is assessed by comparing the post test value with the pre test. The population in this study
were all laboring mothers with normal labor at Batara Siang Pangkep Hospital. The number of samples in this study
were 16 people. Sampling with purposive sampling method. The instruments used were SOAP observation sheet of
patented deep breathing technique, comparative plain scale to measure the level of pain before and after the action
and questionnaire sheet containing maternal demographic data, namely: name, age, occupation, education, and
parity. Data analysis with univariate to determine the frequency distribution of the characteristics of respondents and
bifariate analysis with the help of SPSS with paried t test (Annweiler et al., 2020; Been et al., 2020).
19
Result and Discussion
Univariate Analysis
Table 1
Frequency Distribution of Respondent Characteristics
Respondent Characteristics
N
Frequency
Percentage (%)
Age
18-27 years old
6
37.5
28-40 years old
10
62.5
total
16
100
Occupation
Working
5
31.2
Not Work
11
68.8
total
16
100
Education
Elementary
2
12.5
Middle
4
25
High School
9
56.2
Undergraduate
1
6.3
total
16
100
Parity
Primipara
10
62.5
Multipara
5
31.2
Grandmultipara
1
6.3
total
16
100
Source: Primary Data
Table 2
Frequency distribution of pain levels before and after Deep Breathing Relax
Level Pain
Postest
N
%
N
%
Mild
-
-
6
25.0
Medium
5
31.2
10
75.0
Heavy
11
68.8
-
-
Total
16
100
16
100
Source: Primary Data
Based on table 2 shows that before the back massage was analyzed, the most dominant pain was felt on a heavy pain
scale as many as 11 respondents with a percentage of (68.8) and 5 respondents with a percentage of (31.2) on a
medium pain scale. After the back massage treatment, the results showed a change in the intensity of the pain felt,
there was an increase in the mild pain scale as many as 6 respondents with a percentage of (25.0) and medium pain
as many as 10 respondents with a percentage of (75.0) (Muhler et al., 1992; Rouse etal., 1999).
Bivariate Analysis
Bivariate analysis is used to obtain an overview of whether there is a correlation between the independent variable
and the dependent variable. The results of this Bivariate analysis are presented in tabular form as follows:
Table 3
Dependent T Test Analysis of the Effect of Deep Breathing Relax on Labor Pain Intensity in the Active Phase
Treatment
N
Mean
SD
P-Value
Pretest
8
7.00
1.069
0.000
Postest
8
4.38
1.302
Source: paried t test
20
Based on table 3, the average pain intensity before the deep breathing relax technique is 7.00 heavy pain with a
standard deviation of 1.069, while after treatment it is 4.38 medium pain with a standard deviation of 1.302. P <
0.000 means that there is an influence between pain scores before and after deep breathing relax, thus it is concluded
that the deep breathing relax technique is effective in reducing the intensity of labor pain in the Active phase. Based
on table 3 shows that the distribution of respondents before the deep breathing relax technique was carried out, most
of the respondents experienced severe pain as many as 11 people (68.8%), while in the results after being given Deep
Breathing Relax most of the respondents experienced a decrease in pain to medium, namely 10 people (75%) and
mild as many as 6 people (25%) (Bauernschuster & Schlotter, 2015; Simkin & Bolding, 2004).
Pain is a condition in the form of unpleasant feelings that are very subjective because feelings of pain are
different in each person in terms of scale or level, and only that person can explain or evaluate the pain he is
experiencing (Yuliasari &Santriani, 2018). One of the factors that cause pain in labor is anxiety/ fear in laboring
women will stimulate sympathetic nerves which result in spasm of uterine muscles resulting in ischemia of the
uterine muscles, as a result there is a lack of oxygen in the uterine muscles which stimulates the release of
prostaglandins to cause pain, and pain due to cervical dilatation stimulates the pain response to the cervical and
vertebral ganglion and then to the hypothalamus (Herawati, 2016).
In reducing pain can use respiratory relaxation techniques because it can increase concentration so that it makes it
easier to regulate breathing. If breathing can be regulated, oxygen in the blood will increase so as to provide a sense
of calm, reduce heart rate, and blood pressure so that pain will decrease (Hindriati, 2017). Relaxation is an effective
method to reduce pain which is an unpleasant sensory and emotional experience. One way to reduce pain is by
means of respiratory relaxation techniques. Relaxation techniques are techniques that can reduce the tension
experienced by laboring mothers and their babies, (Biswan et al., 2017). Maintaining components of the sympathetic
nervous system in a homeostatic state so that there is no increase in blood supply, reducing anxiety and fear so that
the mother can adapt to pain during labor and is more effective since pregnancy (Marmi, 2016).
Breathing is controlled automatically by the respiratory center in the brain, this respiratory center will respond to
carbon dioxide levels in the blood flowing through the center so that differences in carbon dioxide levels will disrupt
breathing patterns (fast and deep breaths) to normalize levels. Conditions of fear, anxiety, anger, frustration, pain or
the onset of strong contractions during labor will result in the use of oxygen and produce excessive carbon dioxide.
Encourage the mother to exhale slowly and forcefully. This breathing is done with the aim of preventing respiratory
distress and prolonged hyperventilation (Sonya & Monica, 2018).
From the calculation of data analysis using the Paired T test, the P value is 0.000 while the α value is 0.05. Due to
the value of P Value < α, Ho is rejected Ha is accepted, meaning that there is an effect of deep breathing relax
technique on the intensity of labor pain during the active phase at Batara siang Pangkep Hospital. Based on the
results of the study, it can be concluded that deep breathing techniques can reduce pain intensity in the active phase,
where before the pain intervention was carried out on a scale of 5.04 with a standard deviation of 1.595 and a
standard error of 0.4. After the intervention of deep breathing techniques, the pain intensity is on a scale of 4.07 and
a standard deviation of 1.163 where the standard error is 0.3. The results showed that there was a relationship
between the deep breathing technique method and the decrease in active phase labor pain intensity (Jarrah et al.,
2022; Chung et al., 2010).
From the results of this study, there is a significant difference in pain before and after being given deep breath
relaxation techniques, because the benefits of deep breath relaxation techniques can provide a sense of comfort to the
mother. Respiratory relaxation is one of the most useful skills to overcome labor pain. Respiratory relaxation skills to
overcome this pain can be used during labor in order to cope well with labor means not being overwhelmed or
panicked when facing a series of contractions. Women who use these skills usually feel less pain than women who
do not use them. Relaxation is the most commonly used non-pharmacological pain control method in the UK, in a
study reported by Steer in 1993 that 34% of women used relaxation techniques (Mander, 2012).
According to the researcher's assumption that during the labor process, deep breath relaxation techniques will
reduce pain. Mothers who do the deep breath relaxation technique will decrease their pain according to the his/
contractions experienced. The stronger the contractions, the more pain is felt. With the provision of deep breath
relaxation techniques, it can be concluded that there is a positive influence for laboring mothers who perform deep
breath relaxation techniques compared to mothers who do not perform deep breath relaxation techniques during the
labor process. Overall, based on what the researchers have observed, all respondents on average said that the labor
pain felt reduced and felt more comfortable even though the responses given were different (Notoatmodjo, 2012;
Lowe, 2002; Huntley et al., 2004).
21
Conclusion
After the author conducts the research, it can be concluded that from the results of the calculation of data analysis
using the Paired T test, the P value is 0.000 while the α value is 0.05. Due to the value of P Value < α, Ho is rejected
Ha is accepted, meaning that there is an effect of deep breathing relax technique on labor pain intensity in the Active
phase at Batara siang Pangkep Hospital. It is expected for mothers to add knowledge about the importance of doing
deep breathing relaxation techniques to reduce the intensity of pain, especially when facing the onset of labor, and
for health workers to apply the deep breath relaxation technique that can be used as a consideration for midwives in
providing maternal care in order to reduce the level of pain and pain in facing childbirth.
Acknowledgments
Our deepest gratitude goes to all those who have been involved and helped complete this research, especially to the
research team who have coordinated well enough so that we can complete this research.
References
Alwan, M. K., & Mohsen, R. I. A. (2022). Impact of deep breathing exercise on oxygen saturation of patients with
coronavirus disease. International Journal of Health Sciences, 6(S2), 85718579.
https://doi.org/10.53730/ijhs.v6nS2.7107
Annisa, M., Herni, J., & Stephanie, S. L. (2017). Asuhan Persalinan Normal dan Bayi Baru Lahir.
Annweiler, C., Hanotte, B., de l’Eprevier, C. G., Sabatier, J. M., Lafaie, L., & Célarier, T. (2020). Vitamin D and
survival in COVID-19 patients: A quasi-experimental study. The Journal of steroid biochemistry and molecular
biology, 204, 105771. https://doi.org/10.1016/j.jsbmb.2020.105771
Astuti, T., & Bangsawan, M. (2019). Aplikasi Relaksasi Nafas Dalam Terhadap Nyeri Dan Lamanya Persalinan Kala
I Ibu Bersalin Di Rumah Bersalin Kota Bandar Lampung. Jurnal Ilmiah Keperawatan Sai Betik, 15(1), 59-65.
Bauernschuster, S., & Schlotter, M. (2015). Public child care and mothers' labor supplyEvidence from two quasi-
experiments. Journal of Public Economics, 123, 1-16. https://doi.org/10.1016/j.jpubeco.2014.12.013
Been, J. V., Ochoa, L. B., Bertens, L. C., Schoenmakers, S., Steegers, E. A., & Reiss, I. K. (2020). Impact of
COVID-19 mitigation measures on the incidence of preterm birth: a national quasi-experimental study. The
Lancet Public Health, 5(11), e604-e611. https://doi.org/10.1016/S2468-2667(20)30223-1
Biswan, M., Novita, H., & Masita, M. (2017). Efek Metode Non Farmakologik terhadap Intensitas Nyeri Ibu
Bersalin Kala I. Jurnal Kesehatan, 8(2), 282-288.
Budiana, Y. (2021). Buku Ajar Asuhan Keperawatan pada Pasien dengan Gangguan Sistem Muskoleskeletan.
Sumatra Barat: Yayasan Pendidikan Cendekia Muslim.
Chung, L. J., Tsai, P. S., Liu, B. Y., Chou, K. R., Lin, W. H., Shyu, Y. K., & Wang, M. Y. (2010). Home-based deep
breathing for depression in patients with coronary heart disease: A randomised controlled trial. International
journal of nursing studies, 47(11), 1346-1353. https://doi.org/10.1016/j.ijnurstu.2010.03.007
Dinas Kesehatan Provinsi Sulawesi Selatan 2021, profil kesehatan propinsi Sulawesi Selatan.
Fitri, L., Nova, S., & Nurbaya, R. (2019). Hubungan Teknik Nafas Dalam Terhadap Pengurangan Intensitas Nyeri
Kala I Fase Aktif di Klinik Pratama Jambu Mawar. Jurnal Endurance, 4(2), 419-425.
Fitri, L., Nova, S., & Nurbaya, R. (2019). Hubungan Teknik Nafas Dalam Terhadap Pengurangan Intensitas Nyeri
Kala I Fase Aktif di Klinik Pratama Jambu Mawar. Jurnal Endurance, 4(2), 419-425.
Herawati, R. (2016). Evaluasi Tehnik Relaksasi Yang Paling Efektif Dalam Penatalaksanaan Nyeri Persalinan Kala I
Terhadap Keberhasilan Persalinan Normal. Jurnal Martenity and Neonatal, 4(1), 102-113.
Hidayat, A. A. (2017). Metodologi penelitian keperawatan dan kesehatan. Jakarta: Salemba Medika, 88.
Hindriati, T. (2017). Pengaruh masase dan relaksasi pernafasan terhadap lamanya persalinan kala I fase aktif di
rumah bersalin Kota Jambi tahun 2015. Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public
Health), 1(2), 121-131.
Huntley, A. L., Coon, J. T., & Ernst, E. (2004). Complementary and alternative medicine for labor pain: a systematic
review. American journal of obstetrics and gynecology, 191(1), 36-44. https://doi.org/10.1016/j.ajog.2003.12.008
Indrayani & Djami, M. (2016). Update asuhan persalinan dan bayi baru lahir. Jakarta: CV Trans Info Media.
Jarrah, M. I., Hweidi, I. M., Al-Dolat, S. A., Alhawatmeh, H. N., Al-Obeisat, S. M., Hweidi, L. I., ... & Alkouri, O.
A. (2022). The effect of slow deep breathing relaxation exercise on pain levels during and post chest tube
removal after coronary artery bypass graft surgery. International Journal of Nursing Sciences, 9(2), 155-161.
https://doi.org/10.1016/j.ijnss.2022.03.001
Lowe, N. K. (2002). The nature of labor pain. American journal of obstetrics and gynecology, 186(5), S16-S24.
https://doi.org/10.1016/S0002-9378(02)70179-8
22
Mander, R. (2012). Nyeri Persalinan. Jakarta: EGC.
Marmi. (2016). Asuhan Kebidanan Pada Persalinan. Yogyakarta: Pustaka Belajar.
Muhler, M., Schlögl, R., & Ertl, G. (1992). The nature of the iron oxide-based catalyst for dehydrogenation of
ethylbenzene to styrene 2. Surface chemistry of the active phase. Journal of Catalysis, 138(2), 413-444.
https://doi.org/10.1016/0021-9517(92)90295-S
Notoatmodjo, S. (2012). Metodologi Penelitian Kesehatan, Jakarta, PT Rineka Cipta. Profil SMA, 2.
Rouse, D. J., Owen, J., & Hauth, J. C. (1999). Active-phase labor arrest: oxytocin augmentation for at least 4
hours. Obstetrics & Gynecology, 93(3), 323-328. https://doi.org/10.1016/S0029-7844(98)00448-7
Simkin, P., & Bolding, A. (2004). Update on nonpharmacologic approaches to relieve labor pain and prevent
suffering. Journal of Midwifery & Women's Health, 49(6), 489-504. https://doi.org/10.1016/j.jmwh.2004.07.007
Sonya, Y. E., & Monica, E. (2018). Kebidanan Teori dan Asuhan (Vol. 1). Jakarta: ECG.
Sugiyono. (2017). Metode Penelitian Kuantitatif Kualitatif dan R&D. Bandung: Alfabeta CV.
Wahyuni, W., & Maghfiroh, F. K. U. (2022). The effect of deep breathing exercise in minimizing pain level of
primary dysmenorrhea: Study at physiotherapy students of Universitas Muhammadiyah Surakarta. International
Journal of Health Sciences, 6(S3), 1174511753. https://doi.org/10.53730/ijhs.v6nS3.8828
World Health Organization (WHO). 2020. Kematian Ibu dan Anak., diunduh dari URL: http://puskesmas-oke.
(diakses Tahun 2022).
Yuliasari, D., & Santriani, E. S. (2018). Hubungan Counterpressure Dengan Nyeri Persalinan Pada Ibu Bersalin Kala
I Fase Aktif Ibu Primipara Di Bps Hj. Sulastri, Amd. Keb Pekalongan Lampung Timur Tahun 2013. Jurnal
Kebidanan Malahayati, 1(1).
ResearchGate has not been able to resolve any citations for this publication.
Article
Full-text available
Dysmenorrhea is a lower abdomen pain during menstruation that can interfere with daily activities. Based on its pathophysiology, dysmenorrhea is classified into two, namely primary dysmenorrhea and secondary dysmenorrhea. The existence of physiotherapy modalities in the form of deep breathing exercises is one form that can reduce menstrual pain so that menstrual pain cannot interfere with daily activities. The purpose of the study is to find out the effect of deep breathing exercise on the reduction of primary dysmenorrhea pain. This research method is a quasi-experiment with one group pretest-posttest. The sample taken in the study amounted to 30 respondents using purposive sampling. The Wilcoxon test showed (p = 0.00 < 0.05) that it can be concluded that there is an effect of giving deep breathing exercises in the reduction of primary menstrual pain in physiotherapy students semester 1-5 University of Muhammadiyah Surakarta. There is an effect of giving breathing relaxation techniques to decrease primary menstrual pain (dysmenorrhea) in physiotherapy students semester 1-5 University of Muhammadiyah Surakarta.
Article
Full-text available
An experimental comparative study design was done for 30 patients to assess the impact of deep breathing exercises and chest physiotherapy on the oxygen saturation of patients with COVID19 in Imam Hussein Teaching Hospital and Al Rifai General Hospital/ Thi Qar. The reliability of the questionnaire was achieved through a pilot study and then presented to experts to prove its validity. The total number of items was 40-items in two questionnaires and measure oxygen saturation for five days before and after deep breathing exercises and chest physiotherapy. The data was collected by using simple random methods and analyzed by the application of a descriptive and inferential statistical data analysis approach.Results: The results showed for 30 patients there was significant improvement in oxygen saturation values after chest breathing exercises and deep breathing exercises from 82.3333 ± 2.78337 in first before intervention day to 93.5000 ±1.38340 in day five after chest breathing exercises and deep breathing exercises at P < 0.05. Also there were no significant statistical correlation between patient's age and their oxygen saturation after chest breathing exercises and deep breathing exercises at P ˃ 0.05.
Article
Full-text available
Background Preterm birth is the leading cause of child mortality globally, with many survivors experiencing long-term adverse consequences. Preliminary evidence suggests that numbers of preterm births greatly reduced following implementation of policy measures aimed at mitigating the effects of the COVID-19 pandemic. We aimed to study the impact of the COVID-19 mitigation measures implemented in the Netherlands in a stepwise fashion on March 9, March 15, and March 23, 2020, on the incidence of preterm birth. Methods We used a national quasi-experimental difference-in-regression-discontinuity approach. We used data from the neonatal dried blood spot screening programme (2010–20) cross-validated against national perinatal registry data. Stratified analyses were done according to gestational age subgroups, and sensitivity analyses were done to assess robustness of the findings. We explored potential effect modification by neighbourhood socioeconomic status, sex, and small-for-gestational-age status. Findings Data on 1 599 547 singleton neonates were available, including 56 720 births that occurred after implementation of COVID-19 mitigation measures on March 9, 2020. Consistent reductions in the incidence of preterm birth were seen across various time windows surrounding March 9 (± 2 months [n=531 823] odds ratio [OR] 0·77, 95% CI 0·66–0·91, p=0·0026; ± 3 months [n=796 531] OR 0·85, 0·73–0·98, p=0·028; ± 4 months [n=1 066 872] OR 0·84, 0·73–0·97, p=0·023). Decreases in incidence observed following the March 15 measures were of smaller magnitude, but not statistically significant. No changes were observed after March 23. Reductions in the incidence of preterm births after March 9 were consistent across gestational age strata and robust in sensitivity analyses. They appeared confined to neighbourhoods of high socioeconomic status, but effect modification was not statistically significant. Interpretation In this national quasi-experimental study, initial implementation of COVID-19 mitigation measures was associated with a substantial reduction in the incidence of preterm births in the following months, in agreement with preliminary observations elsewhere. Integration of comparable data from across the globe is needed to further substantiate these findings and start exploring underlying mechanisms. Funding None.
Article
Full-text available
Pain is one of the processes during the labor, the pain during the labor is able to increase the blood pressure, the fetal heart rate also increased and the focus of mothers during the childbirth is disturbed. According to data research shown that 60% primipara describes the pain caused by huge contraction, 30% about medium. In multipara, 45% feel a huge pain, 30% is medium and the lower about 25%. The purpose of this research is to understand the effectivity of the proper way to the non-pharmacological pain management for the phase 1. This research used a quasi-experimental design with the pre-post test without control group design methods. The population used in this research is maternal with phase 1 on an active postpartum. The gaining of a sample using a quota sampling technic consists of 60 maternal who were divided into two groups of 30 respondents per each. The results obtained in this research given the average degree of pain after the relaxation techniques and massage. (The group I) is 5, 47 with the result of p=0.001. The average degree of pain result after having a warm and cold compress for (the group II) is 6,60 ± 1,003 with the result of p=0.000. The conclusions of the research are there are effects in an adduction of deep breathing relaxation technique such of: the back massage, cold and warm compresses toward the decreasing of pain for phase 1 active labor. The deep breath relaxation method and back massage are more effective than cold and warm compresses in relieving pain intensity for the maternal.
Article
Vitamin D may be a central biological determinant of COVID-19 outcomes. The objective of this quasi-experimental study was to determine whether bolus vitamin D3 supplementation taken during or just before COVID-19 was effective in improving survival among frail elderly nursing-home residents with COVID-19. Sixty-six residents with COVID-19 from a French nursing-home were included in this quasi-experimental study. The “Intervention group” was defined as those having received bolus vitamin D3 supplementation during COVID-19 or in the preceding month, and the “Comparator group” corresponded to all other participants. The primary and secondary outcomes were COVID-19 mortality and Ordinal Scale for Clinical Improvement (OSCI) score in acute phase, respectively. Age, gender, number of drugs daily taken, functional abilities, albuminemia, use of corticosteroids and/or hydroxychloroquine and/or antibiotics (i.e., azithromycin or rovamycin), and hospitalization for COVID-19 were used as potential confounders. The Intervention (n = 57; mean ± SD, 87.7 ± 9.3years; 79 %women) and Comparator (n = 9; mean, 87.4 ± 7.2years; 67 %women) groups were comparable at baseline, as were the COVID-19 severity and the use of dedicated COVID-19 drugs. The mean follow-up time was 36 ± 17 days. 82.5 % of participants in the Intervention group survived COVID-19, compared to only 44.4 % in the Comparator group (P = 0.023). The full-adjusted hazard ratio for mortality according to vitamin D3 supplementation was HR = 0.11 [95 %CI:0.03;0.48], P = 0.003. Kaplan-Meier distributions showed that Intervention group had longer survival time than Comparator group (log-rank P = 0.002). Finally, vitamin D3 supplementation was inversely associated with OSCI score for COVID-19 (β=-3.84 [95 %CI:-6.07;-1.62], P = 0.001). In conclusion, bolus vitamin D3 supplementation during or just before COVID-19 was associated in frail elderly with less severe COVID-19 and better survival rate.
Article
Public child care is expected to assist families in reconciling work with family life. Yet, empirical evidence for the relevance of public child care to maternal employment is inconclusive. We exploit the introduction of a legal claim to a place in kindergarten in Germany, which was contingent on day-of-birth cut-off dates and resulted in a marked increase in kindergarten attendance of three-year olds in the following years. Instrumental variable and difference-indifferences estimations on two individual-level data sets yield large and positive effects of public child care on maternal employment. A set of placebo treatment tests corroborate the validity of our identification strategies.
Article
The combination of an XPS/UPS surface analysis instrument with a microreactor allowed the investigation of the surface composition of catalysts characterized by varying activities and selectivities. The active surface is a potassium iron oxide with a 1 : I atomic ratio of K : Fe, whereby iron is only in its trivalent state. Conversion of oxidic oxygen to OH groups is detrimental to the activity. No significant amount of promotor additives is present in the active surface. The process of regeneration with steam removes carbonaceous deposits but cannot reoxidize iron from Fe2+ to Fe3+. A constant but small amount of potassium carbonate that cannot be increased by addition of CO2 to the feed of the working catalyst is present at the surface. Catalysts are precursors, active materials, and irreversibly deactivated samples were studied by SEM and TEM. The surface morphology as well as the microstructure clearly indicates a solid as the active phase. This phase is generated and maintained through solid-state reactions during operation. A potassium-rich liquid film with a thickness exceeding one monolayer can be ruled out for the catalyst performance. Formation of droplets of KOH in certain regions of the catalyst signals bulk structural desintegration of the active material.
Article
The primary aim of this study was to examine the effect of a home-based deep-breathing training programme on depressive symptoms as compared with a control condition (i.e., weekly telephone support) in patients with coronary heart disease (CHD). This efficacy trial used a randomised controlled, parallel group design. A total of 62 CHD patients with a Beck Depression Inventory-II (BDI-II) >10 were randomised to receive either home-based deep-breathing training (experimental group, n=28) or weekly telephone support (control group, n=34). Both participants and data assessors were blinded to the study hypothesis. The primary outcome measure was the change in the self-reported depressive symptom severity, measured by the BDI-II. The secondary outcome was the change in the Patient Health Questionnaure-9 (PHQ-9)-assessed depressive symptom severity. Depressive symptoms were assessed at baseline and post-test in both groups. For the experimental group, depressive symptoms were also assessed at the end of the first 2 weeks of training. The post-test BDI-II and PHQ-9 were significantly lower in the experimental group than in the control group (p<0.001 and p<0.001, respectively). The decreases in BDI-II, from baseline, at post-test were significantly greater in the experimental group as compared with the control group (95% confidence interval (CI): -12.554 to -5.408, p<0.001). Similarly, the pre-test-to-post-test change in PHQ-9 scores was significantly greater in the experimental group as compared with the control group (95% CI: -5.59 to -0.092, p=0.007). Examining the changes in BDI-II and PHQ-9 within the experimental group by the repeated-measures analysis of variance (ANOVA) revealed that both measures of depressive symptoms decreased significantly over time (both p<0.001). The percentage of participants with a BDI-II >or=17 decreased over time from 28.6% at baseline, and 17.9% during treatment, to 10.7% post-test. Home-based deep-breathing training is effective in reducing depressive symptoms as compared with telephone support in patients with CHD.
Article
To assess a labor-management protocol that mandated at least 4 hours of oxytocin augmentation before cesarean delivery for active-phase labor arrest. We prospectively evaluated term gravidas in spontaneous labor with active-phase labor arrest (cervix at least 4 cm dilated and 1 cm or less of cervical progress in 2 hours). Exclusion criteria included nonvertex presentation, previous cesarean, multiple gestation, and a nonreassuring fetal heart rate tracing or chorioamnionitis at the time of labor arrest. After the diagnosis of active-phase arrest, oxytocin was initiated with an intent to achieve a sustained uterine contraction pattern of greater than 200 Montevideo units. Cesarean delivery was not performed for labor arrest until at least 4 hours of a sustained uterine contraction pattern of greater than 200 Montevideo units, or a minimum of 6 hours of oxytocin augmentation if this contraction pattern could not be achieved. Five hundred forty-two women were managed by the protocol, and 92% delivered vaginally. The subsequent vaginal delivery rate for parous women who had not progressed (1 cm of cervical dilation or less) despite 2 hours of oxytocin augmentation was 91%, and it was 74% for nulliparas. With no labor progress after 4 hours of oxytocin augmentation, the subsequent vaginal delivery rates were 88% for parous women and 56% for nulliparas. There were no severe maternal complications. One neonate had persistent fetal circulation and one had a positive blood culture, but both did well. Extending the minimum period of oxytocin augmentation for active-phase labor arrest from 2 to at least 4 hours was effective and safe.