Introduction: Football and futsal are associated with a high risk of injuries and consequently, the development of mental health problems. Health and wellness programs aimed at reducing the incidence of injuries, but these areas remain insufficiently explored in the literature, therefore, their effectiveness is still uncertain. Objective: This study aimed to present a systematic review that
... [Show full abstract] analyzes the effects of health and well-being programs on the incidence of injuries in football and futsal athletes. Methodology: A search was conducted in PubMed, EBSCO, and Web of Science databases to select relevant literature on the topic. The selected literature was based on health and wellness programs applied to football players, and after implementation, the difference in the incidence of injuries examined. Studies that used experimental study design to compare athletes before and after the intervention were selected. Results: Based on the physiotherapy evidence database scale, criteria were applied to assess the interventions’ evidence. Seven studies were classified as having good methodological quality, while four were classified as moderate and one as poor. From a total of 329, 12 studies were selected based on the eligibility criteria. Conclusions: The different studies selected addressed various types of programs (e.g., Mindfulness, Stress Inoculation Therapy and Biofeedback, Psychological and physiotherapy, Yoga). The programs reduced the incidence of sports injuries in football athletes and improved individual and team performance and reduced muscle tension. However, research is scarce, while studies are needed.