Identification of suitable candidates for durable mechanical circulatory support (MCS), it is crucial to conduct a comprehensive and systematic evaluation of potential medical comorbidities. This assessment should follow a methodical head-to-toe approach. Organ systems to assess include neurological, cardiovascular, pulmonary, liver and gastrointestinal tract, renal, and hematology. Other
... [Show full abstract] critical assessments include obesity, age and frailty, malignancy and psychosocial considerations. Chemical dependency including tobacco and alcohol affects patients’ self-care ability and implantation in such candidates is considered a relative contraindication.