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Covid19 Vaccines and the Misinterpretation of Perceived Side Covid19 Vaccines and the Misinterpretation of Perceived Side
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Covid 19 vaccines and the misinterpretation of
perceived side effects clarity on the safety of vaccines
Raymond D. Palmer
Full Spectrum Biologics, South Perth, WA, 6151, Australia
Full Spectrum Biologics, WA, 6102, Australia
In the era of Covid 19 and mass vaccination programs, the anti-vaccination movement across the world is currently at
an all-time high. Much of this anti-vaccination sentiment could be attributed to the alleged side effects that are
perpetuated across social media from anti-vaccination groups.
Fear mongering and misinformation being peddled by people with no scientiﬁc training to terrorise people into
staying unvaccinated is not just causing people to remain susceptible to viral outbreaks, but could also be causing more
side effects seen in the vaccination process. This brief review will offer data that may demonstrate that misinformation
perpetuated by the anti-vaccination movement may be causing more deaths and side effects from any vaccine.
A mini review of published literature has been conducted and found that mental stress clearly causes vasoconstriction
and arterial constriction of the blood vessels. Therefore, if subjects are panicked, concerned, stressed or scared of the
vaccination, their arteries will constrict and become smaller in and around the time of receiving the vaccine. This bio-
logical mechanism (the constriction of veins, arteries and vessels under mental stress) is the most likely cause for where
there has been blood clots, strokes, heart attacks, dizziness, fainting, blurred vision, loss of smell and taste that may have
been experienced shortly after vaccine administration. The extreme mental stress of the patient could most likely be
attributed to the fear mongering and scare tactics used by various anti-vaccination groups.
This paper does not aim to rule in or out every side effect seen, but it is highly likely that many apparent side effects
seen shortly after a subject has received a vaccine could be the result of restricted or congested blood ﬂow from blood
vessel or arterial constriction caused by emotional distress or placebo based on fear around vaccines.
Keywords: Covid 19, Vaccines, Side effects, Misinterpretation, Ischemia, Stress, Cardiovascular
Vaccines introduced in late 2020 or early 2021
were closely watched, scrutinised, and
monitored by the world's mainstream population due
to their fast to market delivery. Subsequent health
concerns were quickly made public across social
media and news outlets driving further vaccine hes-
itancy. One of the most common health concerns was
that various types of Covid 19 vaccines were causing
strokes or blood clots. The science for the vaccines
causing blood clots has not been found, but other
causes for this cascade from vaccines to blood clotting
events may be found in existing medical literature.
Covid 19 vaccines use many of the same in-
gredients that have been safely used for many years,
with the only major difference being the mRNA
[1,2]. However, anti-vaccination sentiment and side
effects are at an all time high, and this may point to a
Vaccines include antigens that produce an im-
mune response which is adept at providing protec-
tion from disease . However, reactogenicity from
vaccines is very rare according to Herve et al. and
mostly associated with mild irritations or other
discomfort at the site of injection. Once vaccine
antigens enter the body, they are distinguished as
pathogens by the body's immune system, the path-
ogen-associated molecular patterns (PAMPs) or
damage-associated molecular patterns (DAMPs),
pattern-recognition receptors (PRRs), including
Toll-like receptors (TLR) that are located on pe-
ripheral circulating immune cells [3,4].
Even though the likelihood of mental stress
causing strokes, heart attacks or blood clots may at
Received 12 March 2022; revised 20 April 2022; accepted 4 May 2022.
Available online 01 September 2022.
E-mail address: email@example.com.
2211-8039/Published by China Medical University 2022. ©the Author(s). This is an open access article under the CC BY license
ﬁrst appear unlikely, a brief investigation of current
medical literature clearly shows that simple tasks
under clinical observing conditions such as public
speaking can induce serious adverse outcomes .
Krantz et al. demonstrated that subjects with
ischemia from mental stress experienced cardiac
episodes more frequently than subjects without
mental stress ischemia (8 of 34; 23%; p ¼0.048).
Mental stress-induced myocardial ischemia
(MSIMI) is a condition where blood ﬂow to the heart is
restricted due to emotional distress. MSIMI has been
found to be more severe in females when peripheral
blood vessels are constricted . If MSIMI results in
ischemia, itcan also double the chance of a heart attack
or death in subjects where heart disease is present .
Jiang et al. found a signiﬁcant increase in nonfatal and
fatal cardiac events in subjects with MSIMI.
It has been found that the level of microvascular
constriction but not the angiographic burden of
coronary artery disease (CAD) is correlated with
MSIMI . Patients with CAD and exercise induced
ischemia (EII) with the existence of MSIMI were
highly predicted to undergo a loss of life event .
Visceral arteries are also implicated in constriction
from mental stress. Notably the renal artery showed
decreased blood ﬂow during mental stress testing
. The superior mesenteric artery (SMA) did not
display any signiﬁcant difference according to
Hayashi et al. The ﬁndings of renal artery constric-
tion also may lead into serious downstream kidney
events. This data clearly indicates that mental stress
can prevent blood ﬂow far beyond the cardiovas-
cular system inducing many other aberrations.
Adverse cardiovascular events that were reported
from Covid 19 vaccines have been monitored closely
by The World Health Organisation (WHO) . Of
those events, palpitations (717(14.74)), increased
heart rate (439 (9,03), ﬂushing (592(12.17) and
tachycardia (798 (16.41)) were all reported as having
the highest rate of incidence. However, Kaur et al.
does not ﬁnd any causality from the vaccines listed.
Furthermore, restricted blood ﬂow or blockages
caused by MSIMI inducing vasoconstriction could
be the smoking gun in all the aforementioned con-
ditions such as palpitations, increased heart rate,
ﬂushing and tachycardia [12,13].
Vaccines monitored by Kaur et al. were Comirnaty
(BNT162b2), Moderna COVID-19 Vaccine
(mRNA1273), COVID-19 Vaccine AstraZeneca
(AZD1222); also known as Covishield, Sputnik V,
COVID-19 Vaccine Janssen (JNJ-78436735;
Ad26.COV2.S), CoronaVac, BBIBP-CorV, Epi-
VacCorona, Convidicea (Ad5-nCoV), Covaxin, Cov-
Moreover, vasoconstriction could also result in
hyperpnea, postural faint, light headedness or
dizziness which have all been included as possible
side effects from the Covid 19 vaccines [14,15]. Post
vaccine smell and taste disorders have also been
implicated as side effects of Covid 19 vaccines,
however both these disorders may be attributed to
blood ﬂow disorders from mental stress induced
The litany of suspected or perceived side effects
discussed here from Covid 19 vaccines correlates
ﬁrmly with well-established vasoconstriction disor-
ders where blood ﬂow is reduced or blocked
completely. MSIMI is found in 70% of people with
CAD , and it is predicted that approximately 16.3
million Americans above the age of twenty have
CAD. Notably The American Heart Association
(AHA) reports that approximately 82.6 million peo-
ple in the United States have some form of cardio-
vascular disease . When MSIMI is combined
with these conditions, it presents a further aggra-
vated risk for mortality.
The data presented herein, poses an interesting
question, is the fear mongering around vaccines
causing many of these perceived side effects by
inducing unnecessary stress in vulnerable people?
Is the movement and character of anti-vaccination
information that may strike fear into the general
population causing anxiety and vascular constric-
tion resulting in pathologies such as dizziness,
hypernea, fainting, blood clotting, stroke and heart
attack? The science discussed here clearly estab-
lishes that anxiety and fear causes vasoconstriction
disorders, and that a particular movement that is
trying to save people with a profound lack of
scientiﬁc and medical training (the anti-vaccination
movement) from vaccine side effects may actually
be the entity causing the majority of side effects.
Sullivan et al. had demonstrated that MSIMI was
found to be more dangerous in females when pe-
ripheral blood vessels were constricted. When fe-
males underwent a tonometry exam the average ratio
was associated at 0.11e0.35, just over a threefold ratio
. The Centre for Disease Control (CDC) also found
that there was approximately between a three and
fourfold increase in females reporting adverse side
effects than men from the Covid 19 vaccine . The
numbers reported from the CDC were 4296 adverse
side effects from females, and 1056 from men. The
parallel in this data is quite clear, and may profoundly
exonerate Covid 19 vaccines as ground zero for the
perceived side effects and implicate the well estab-
lished and studied condition of MSIMI and other
blood ﬂow conditions as the smoking gun.
VACCINES, MISINTERPRETATION OF SIDE EFFECTS
Apart from MSIMI and other cardiac impairments
discussed here, the placebo effect is also a strong
marker in potential side effects, as the belief in
detrimental side effects (the nocebo effect) can cause
detrimental side effects . It has also been shown
that the placebo effect can be so powerful that it can
affect end-organ functions that are controlled by the
autonomic nervous system . Both the placebo
and nocebo effect are both noted here due to MSIMI
being caused by mental stress, that is the connection
between mental state and biological disorder which
is already well established across the literature. This
shows major cause for concern where fear mon-
gering around vaccines is being perpetuated, as
those with expectations of getting adverse side ef-
fects may increase their risk of experiencing adverse
side effects .
Obesity may also play a role in poor outcomes for
Covid 19 vaccines . Obese subjects also appear to
be at higher risk of MSIMI  which is consistent
with this paper'sﬁndings. An increase in adverse re-
actions was also found in obese subjects when using
the Pﬁzer vaccine . Obesity or poor arterial health
may heighten the chances of a vaccine side effect.
This mini review ﬁnds that subjects with a history of
heart disease, obesity, poor health combined with
extreme stress or fear of vaccines should visit their
medical practitioner and discuss the use of therapies
or medications such as vaso or arterial dilators or
possibly anticoagulants prior to their vaccines, as
these measures under professional guidance may
assist in maintaining healthy blood ﬂow through a
subject's system and may offer beneﬁts to ensure
adverse reactions from underlying health conditions
are not confused withadverse reactions from vaccines.
All data or claims of adverse reactions from vac-
cines should ﬁrst be weighed against a subject's
health history with a focus on their vascular and
arterial systems, cardiologic ﬁtness and propensity
for mental stress induced ischemia.
This brief review is not exhaustive but ﬁnds that it
is highly probable that many adverse reports from
recent vaccines are associated with vasoconstriction
in conjunction with MSIMI or CAD.
This paper also presents the opportunity for gov-
ernments to peer back into the claims of adverse
vaccine side effects and weigh up the volume of
existing health conditions that many of those subjects
may have had. If it can be established in a high volume
of cases of apparent side effectsthat CAD, HD, MSIMI
or EII were present, then the adverse reactions can be
laid against emotional distress or anxiety as opposed
to the vaccines. The cause or source of that emotional
distress and fear must then be investigated, recog-
nised, and managed for future vaccination programs.
Humanity on average has experienced a viral
outbreak every two years for the last decade. So,
managing this alarmism over perceived vaccine side
effects is paramount in delivering fast to market so-
lutions for future vaccination programs.
2.1. Limitations of study
This review is limited by primarily focusing on
vasoconstriction conditions caused by a stress
response, and also by a lack of large-scale clinical trial
studies to determine whether using novel combina-
tions of vasodilators or anticoagulants with vaccines
could reduce vaccine side effects, which may also
assist in clarifying whether side effects were
emanating from vaccines or conditions such as
MSIMI. Further investigation into whether side effects
could be attributed as a stress response is required.
Monday, 22 November 2021.
Raymond D Palmer.
Conﬂict of interest
Raymond D Palmer is Chief Science Ofﬁcer of Full
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