Mimosa pudica is short-lived evergreen shrub commonly known as the “touch-me-not” plant, Chui Mui, Shame plant. Its various parts have therapeutic value. The roots of Mimosa pudica are bitter, astringent, acrid and cooling. They are used in the treatment of ulcers, inflammations, asthma, diarrhea, urinary complaints and fistulas. The plant contains the alkaloid mimosine, and extract of its leaves contains adrenaline-like substance. It has promising pharmacological profile like antibacterial, antivenom, antifertility, anticonvulsant, antidepressant, aphrodisiac etc. The herb has been used traditionally in the treatment of urogenital disorders, dysentery, sinus, and also applied on wounds. The juice of freshly crushed leaves is used internally and externally in piles, to treat cuts and wounds. It is also applied externally to fissures, skin wounds and ulcers. The hemostatic property of Mimosa pudica helps to control bleeding in piles. It is commonly distributed in open-spaces, especially road side, cultivated land and waste area. It has prickly stems and small, fluffy, ball-shaped pink flowers in summer. Its anti-inflammatory activity reduces inflammation and helps to control secondary infections. This paper is an attempt to explore and compile different pharmacognostic aspects of the plant M. pudica.