20220514 - The Myth of the Blind Watchmaker - Topical Bibliography.pdf

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© Charles H. Rixey, 2022
Charles H Rixey, MA
The Myth of the Blind Watchmaker
Dr. Fauci’s response to the publication of Pradhan et al on 1/31/2020 – in the form of scientific
censorship – had massive implications for our response to the COVID-19 pandemic, and shows
that from the start, he believed it came from a lab.
Linked Topical Bibliography
Research into the HIV connections
1/30/2020 Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag
3/23/2020 WUHAN COVID-19 SYNTHETIC ORIGINS AND EVOLUTION
4/25/2020 Root cause of COVID-19? Biotechnology's dirty secret: Contamination
4/25/2020 COVID-19, SARS and Bats Coronaviruses Genomes Unexpected Exogeneous RNA Sequences
5/15/2020 Guoke Faji 2019/236 and the SARS-CoV-2 Outbreak
6/2/2020 Biovacc-19: A candidate vaccine…..
7/2/2020 The evidence which suggests that this is no naturally evolved virus
8/2/2020 HIV man-manipulated coronavirus genome evolution trends
8/5/2020 Anticovidian v.2 COVID-19: Hypothesis of the Lab Origin vs Zoonotic Event which can also be of a Lab Origin
7/1/2021 Dr. Richard Fleming discusses the HIV inserts
7/15/2021 BASES2021 SARS CoVd2 Gain of Function Research Violations of Law
9/20/2021 PREEMPT - DRASTIC'S Analysis of the DEFUSE Rejection Letter
9/20/2021 PREEMPT - DRASTIC's Analysis of the PREEMPT/DEFUSE Proposal
10/4/2021 Simon Wain-Hobson's analysis of the DEFUSE proposal
10/4/2021 Simon Wain-Hobson's annotated version of the DEFUSE proposal
12/17/2021 QTQTN motif upstream of the furin-cleavage site plays key role in SARS-CoV-2 infection and pathogenesis
12/28/2021 How to BLAST your way to the truth about the origins of COVID-19
2/21/2022 MSH3 Homology and Potential Recombination Link to SARS-CoV-2 Furin Cleavage Site
4/10/2022 Absolute proof: The Gp-120 sequences prove beyond all doubt that "COVID-19" was man-made
Censorship & narrative construction
1/21/2020 An emerging CoV causing pneu. outbreak in Wuhan, China: calling for dev. therapeutic & prophylactic strategies
1/21/2020 A furin cleavage site was discovered in the spike protein of the 2019 nCoV
1/23/2020 Complete genome characterisation of a novel CoV assoc. with severe human respiratory disease in Wuhan, China
1/23/2020 Discovery of a novel CoV associated with the recent pneumonia outbreak in humans and its potential bat origin
1/30/2020 Genomic characterisation and epidemiology of 2019-nCoV: implications for virus origins and receptor binding
1/30/2020 Origins of MERS-CoV, and lessons for 2019-nCoV
2/1/2020 A pneumonia outbreak associated with a new coronavirus of probable bat origin
2/1/2020 The continuing 2019-nCoV epidemic threat of novel CoV to global health - The latest outbreak in Wuhan, China
2/1/2020 Analysis of Wuhan Coronavirus: déjà vu [findings on 1/29, 1st edition on 2/1]
2/2/2020 Quick retraction of coronavirus paper was good moment for science
2/3/2020 Accelerated viral dynamics in bat cell lines, with implications for zoonotic emergence
2/4/2020 HIV-1 did not contribute to the 2019-nCoV genome
2/6/2020 Tackling Rumors of a Suspicious Origin of nCoV2019 - SARS-CoV-2 coronavirus
2/7/2020 NASEM Response to OSTP re Coronavirus_February 6, 2020
2/13/2020 No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2
2/14/2020 The First Disease X is Caused by a Highly Transmissible Acute Respiratory Syndrome Coronavirus
2/16/2020 The proximal origin of SARS-CoV-2
2/19/2020 Is SARS-CoV-2 originated from laboratory? A rebuttal to the claim of formation via laboratory recombination
2/19/2020 Statement in support of the scientists, public health prof., and medical prof. of China combatting COVID-19
5/1/2020 A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells
8/28/2020 The Mutations that Caused Covid-19 Reinfection Explained
9/3/2020 COVID-19 futures: a framework for exploring medium and long-term impacts
1/25/2022 Close Relatives of MERS-CoV in bats use ACE2 as their functional receptors [NeoCoV]
3/4/2022 Luc Montagnier (1932–2022) - Obituary
4/1/2022 The Animal Origin of Major Human Infectious Diseases: What Can Past Epidemics Teach Us About Preventing
the Next Pandemic?
4/5/2022 Reviewing findings on the polypeptide sequence of the SARS-CoV-2 protein to discuss the origins of the virus

The Myth of the Blind Watchmaker – Topical Bibliography C. H. Rixey
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China & US HIV-CoV Vaccine & Therapeutics Research [by research focus]
HIV-SARS Pseudovirus etc.
1/28/2004 Expression cloning of functional receptor used by SARS coronavirus - ScienceDirect
7/1/2006 Preparation of a Chimeric Armored RNA as a Versatile Calibrator for Multiple Virus Assays
9/28/2021 The SARS CoV-2 spike directed non-neutralizing polyclonal antibodies cross-react with HIV-1 gp41
Spike Protein, other
7/1/2005 Evaluating the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of the envelope glycoprotein
complex of HIV-1
9/16/2005 Structure of SARS Coronavirus Spike Receptor-Binding Domain Complexed with Receptor
4/1/2010 Recombination, reservoirs, and the modular spike: mechanisms of coronavirus cross-species transmission
7/14/2010 TMPRSS2 and TMPRSS4 facilitate trypsin-independent spread of influenza virus in Caco-2 cells
HIV Vaccine design
1/1/2005 Development of Mouse Hepatitis Virus and SARS-CoV Infectious cDNA Constructs
5/23/2012 A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing
antibodies
7/15/2012 Extended Follow-up Confirms Early Vaccine-Enhanced Risk of HIV Acquisition and Demonstrates Waning
Effect Over Time Among Participants in a Randomized Trial of Recombinant Adenovirus HIV Vaccine
8/4/2014 Stabilizing the Native Trimer of HIV-1 Env by Destabilizing the Heterodimeric Interface of the gp41 Post fusion
Six-Helix Bundle
8/21/2017 Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529
5/15/2018 HIV-1 Vaccines Based on Antibody Identification, B Cell Ontogeny, and Epitope Structure
7/1/2019 Presentation of HIV-1 envelope glycoprotein trimers on diver…
12/9/2020 Stabilized diverse HIV-1 envelope trimers for vaccine design
11/24/2021 Structure-guided envelope trimer design in HIV-1 vaccine development: a narrative review
Peptide Fusion Inhibitors
5/1/2003 Model of the pre-insertion region of the spike (S2) fusion glycoprotein of the human SARS-
CoV: implications for antiviral therapeutics
6/1/2003 Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategy
5/1/2004 Structural similarity between HIV-1 gp41 and SARS-CoV S2 proteins suggests an analogous membrane fusion
mechanism
4/12/2006 Inhibition of SARS-associated CoV infectivity by peptides analogous to the viral spike protein
5/1/2009 Structures and Mechanisms of Viral Membrane Fusion Proteins
6/1/2012 Discovery of Critical Residues for Viral Entry and Inhibition through Structural Insight of HIV-1 Fusion
Inhibitor CP621–652
12/7/2012 A bivalent recombinant protein inactivates HIV-1 by targeting the gp41 prehairpin fusion intermediate induced
by CD4 D1D2 domains
1/22/2013 HIV-1 Fusion Is Blocked through Binding of GB Virus C E2D Peptides to the HIV-1 gp41 Disulfide Loop
1/2/2015 Design of a highly potent HIV-1 fusion inhibitor targeting t...
5/15/2016 Development of potent and long-acting HIV-1 fusion inhibitor...
5/12/2017 A Lipopeptide HIV-1/2 Fusion Inhibitor with Highly Potent In Vitro, Ex Vivo, and In Vivo Antiviral Activity
4/10/2019 A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike
2/11/2020 Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein
3/2/2020 Medical Countermeasures Analysis of 2019-nCoV and Vaccine Risks for Antibody-Dependent Enhancement
3/30/2020 Inhibition of SARS-CoV-2 infection by a highly potent pan-CoV fusion inhibitor targeting its spike protein that
harbors a high capacity to mediate membrane fusion
6/1/2020 Coronavirus membrane fusion mechanism offers a potential target for antiviral development
9/1/2020 Opening the HIV envelope: potential of CD4 mimics as multifunctional HIV entry inhibitors
12/9/2020 Protein- and Peptide-Based Virus Inactivators: Inactivating Viruses Before Their Entry Into Cells
12/11/2020 Inhibition of Coronavirus Entry In Vitro and Ex Vivo by a Lipid-Conjugated Peptide Derived from the SARS-
CoV-2 Spike Glycoprotein HRC Domain
1/9/2021 Pan-coronavirus fusion inhibitors as the hope for today and tomorrow
1/13/2021 Enfuvirtide, an HIV-1 fusion inhibitor peptide, can act as a potent SARS-CoV-2 fusion inhibitor
4/13/2021 Pan-CoV fusion inhibitors possess potent inhibitory activity against HIV-1, HIV-2, and SIV
4/30/2021 Supercoiling Structure-Based Design of a Trimeric Coiled-Coil Peptide with High Potency against HIV-1 and
Human β-Coronavirus Infection
7/29/2021 Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with
preclinical evaluation

The Myth of the Blind Watchmaker – Topical Bibliography C. H. Rixey
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12/31/2021 Discovery of Highly Potent Fusion Inhibitors with Potential Pan-CoV Activity That Effectively Inhibit Major
COVID-19 VOCs in Pseudovirus-Based Assays
3/30/2022 The Need for Speed and Efficiency: A Brief Review of Small Molecule Antivirals for COVID-19
4/11/2022 Coronavirus Entry Inhibitors
4/13/2022 Peptide-Based HIV Entry Inhibitors
Small Molecule Inhibitors
1/15/2000 A Recombinant HIV-1 Envelope Glycoprotein Complex Stabilized by an Intermolecular Disulfide Bond between
the gp120 and gp41 Subunits Is an Antigenic Mimic of the Trimeric Virion-Associated Structure
12/16/2002 Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes
4/16/2004 Synthetic Bivalent CD4-Mimetic Miniproteins Show Enhanced Anti-HIV Activity over the Monovalent
Miniprotein
5/13/2005 Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures,
molecular mimicry, and neutralization breadth
2/1/2010 Protease Cleavage Sites in HIV-1 gp120 Recognized by Antigen Processing Enzymes Are Conserved and
Located at Receptor Binding Sites
8/15/2021 Proposal and protocol for the construction of pEF1-ACE2-IGG2-SMAR vector for gene therapy of SARS-CoV-2
DC-SIGN
1/15/2003 Differential N-Linked Glycosylation of HIV & Ebola Virus Envelope Glycoproteins Modulates Interactions with
DC-SIGN and DC-SIGNR
2/16/2004 DC-SIGN Binds to HIV-1 Glycoprotein 120 in a Distinct but Overlapping Fashion Compared with ICAM-2 and
ICAM-3
10/28/2016 HIV-1 gp120 Glycoprotein Interacting with Dendritic Cell-specific Intercellular Adhesion Molecule 3-grabbing
Non-integrin (DC-SIGN) Down-Regulates Tight Junction Proteins to Disrupt the Blood Retinal Barrier and Increase Its
Permeability
8/10/2020 DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a
glycomimetic antagonist
China & US HIV-CoV Vaccine & Therapeutics Research [combined]
1/15/2000 A Recombinant HIV-1 Envelope Glycoprotein Complex Stabilized by an Intermolecular Disulfide Bond between
the gp120 and gp41 Subunits Is an Antigenic Mimic of the Trimeric Virion-Associated Structure
12/16/2002 Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes
1/15/2003 Differential N-Linked Glycosylation of HIV & Ebola Virus Envelope Glycoproteins Modulates Interactions with
DC-SIGN and DC-SIGNR
5/1/2003 Model of the pre-insertion region of the S2 fusion glycoprotein of the human SARS-
CoV: implications for antiviral therapeutics
6/1/2003 Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategy
1/28/2004 Expression cloning of functional receptor used by SARS coronavirus - ScienceDirect
2/16/2004 DC-SIGN Binds to HIV-1 Glycoprotein 120 in a Distinct but Overlapping Fashion Compared with ICAM-2 and
ICAM-3
4/16/2004 Synthetic Bivalent CD4-Mimetic Miniproteins Show Enhanced Anti-HIV Activity over the Monovalent Minipr.
5/1/2004 Structural sim. between HIV-1 gp41 & SARS-CoV S2 proteins sugg. an analogous membrane fusion mechanism
1/1/2005 Development of Mouse Hepatitis Virus and SARS-CoV Infectious cDNA Constructs
5/13/2005 Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures,
molecular mimicry, and neutralization breadth
7/1/2005 Evaluating the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of the envelope glycoprotein
complex of HIV-1
9/16/2005 Structure of SARS Coronavirus Spike Receptor-Binding Domain Complexed with Receptor
4/12/2006 Inhibition of SARS-associated CoV infectivity by peptides analogous to the viral spike protein
7/1/2006 Preparation of a Chimeric Armored RNA as a Versatile Calibrator for Multiple Virus Assays
5/1/2009 Structures and Mechanisms of Viral Membrane Fusion Proteins
2/1/2010 Protease Cleavage Sites in HIV-1 gp120 Recognized by Antigen Processing Enzymes Are Conserved and
Located at Receptor Binding Sites
4/1/2010 Recombination, reservoirs, and the modular spike: mechanisms of coronavirus cross-species transmission
7/14/2010 TMPRSS2 and TMPRSS4 facilitate trypsin-independent spread of influenza virus in Caco-2 cells
4/18/2011 Hypoxia enhances cancer cell invasion through relocalization of the proprotein convertase furin from the trans‐
golgi network to the cell surface
5/23/2012 A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing
antibodies

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6/1/2012 Discovery of Critical Residues for Viral Entry and Inhibition through Structural Insight of HIV-1 Fusion
Inhibitor CP621–652
7/15/2012 Extended Follow-up Confirms Early Vaccine-Enhanced Risk of HIV Acquisition and Demonstrates Waning
Effect Over Time Among Participants in a Randomized Trial of Recombinant Adenovirus HIV Vaccine
12/7/2012 A bivalent recombinant protein inactivates HIV-1 by targeting the gp41 pre-hairpin fusion intermediate induced
by CD4 D1D2 domains
1/22/2013 HIV-1 Fusion Is Blocked through Binding of GB Virus C E2D Peptides to the HIV-1 gp41 Disulfide Loop
8/4/2014 Stabilizing the Native Trimer of HIV-1 Env by Destabilizing the Heterodimeric Interface of the gp41 Postfusion
Six-Helix Bundle
1/2/2015 Design of a highly potent HIV-1 fusion inhibitor targeting t...
5/15/2016 Development of potent and long-acting HIV-1 fusion inhibitor...
10/28/2016 HIV-1 gp120 Glycoprotein Interacting with Dendritic Cell-specific Intercellular Adhesion Molecule 3-grabbing
Non-integrin (DC-SIGN) Down-Regulates Tight Junction Proteins to Disrupt the Blood Retinal Barrier and Increase Its
Permeability
5/12/2017 A Lipopeptide HIV-1/2 Fusion Inhibitor with Highly Potent In Vitro, Ex Vivo, and In Vivo Antiviral Activity
8/21/2017 Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529
3/22/2018 Controversial HIV Researcher Robert Redfield Is CDC Director
5/15/2018 HIV-1 Vaccines Based on Antibody Identification, B Cell Ontogeny, and Epitope Structure
4/10/2019 A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike
7/1/2019 Presentation of HIV-1 envelope glycoprotein trimers on diver…
2/11/2020 Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein
3/2/2020 Medical Countermeasures Analysis of 2019-nCoV and Vaccine Risks for Antibody-Dependent Enhancement
(ADE) by Darrell Ricke, Robert W. Malone :: SSRN
3/30/2020 Inhibition of SARS-CoV-2 infection by a highly potent pan-CoV fusion inhibitor targeting its spike protein that
harbors a high capacity to mediate membrane fusion
6/1/2020 Coronavirus membrane fusion mechanism offers a potential target for antiviral development
8/10/2020 DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a
glycomimetic antagonist
9/1/2020 Opening the HIV envelope: potential of CD4 mimics as multifunctional HIV entry inhibitors
12/9/2020 Protein- and Peptide-Based Virus Inactivators: Inactivating Viruses Before Their Entry Into Cells
12/9/2020 Stabilized diverse HIV-1 envelope trimers for vaccine design
12/11/2020 Inhibition of CoV Entry In Vitro and Ex Vivo by a Lipid-Conjugated Peptide Derived from the SARS-CoV-2
Spike Glycoprotein HRC Domain
1/9/2021 Pan-coronavirus fusion inhibitors as the hope for today and tomorrow
1/13/2021 Enfuvirtide, an HIV-1 fusion inhibitor peptide, can act as a potent SARS-CoV-2 fusion inhibitor: an in-silico
drug repurposing study
4/13/2021 Pan-CoV fusion inhibitors possess potent inhibitory activity against HIV-1, HIV-2, and SIV
4/30/2021 Supercoiling Structure-Based Design of a Trimeric Coiled-Coil Peptide with High Potency against HIV-1 &
Human β-CoV Infection
7/29/2021 Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with
preclinical evaluation
8/15/2021 Proposal and protocol for the construction of pEF1-ACE2-IGG2-SMAR vector for gene therapy of SARS-CoV-2
9/28/2021 The SARS CoV-2 spike directed non-neutralizing polyclonal antibodies cross-react with HIV-1 gp41
11/24/2021 Structure-guided envelope trimer design in HIV-1 vaccine development: a narrative review
12/31/2021 Discovery of Highly Potent Fusion Inhibitors with Potential Pan-CoV Activity That Effectively Inhibit Major
COVID-19 VOCs in Pseudovirus-Based Assays
3/30/2022 The Need for Speed and Efficiency: A Brief Review of Small Molecule Antivirals for COVID-19
4/11/2022 Coronavirus Entry Inhibitors
4/13/2022 Peptide-Based HIV Entry Inhibitors
SARS-CoV-2 2nd & 3rd order effects
12/15/2004 Hypoxia-enhanced Expression of the Proprotein Convertase Furin Is Mediated by Hypoxia-inducible Factor-1
4/3/2020 The Role of Autophagy in Respiratory Complications of COVID-19
4/13/2020 The potential for ADE of SARS-CoV-2 infection: Translational implications for vaccine development
5/6/2020 The anti‐HIV drug nelfinavir mesylate (Viracept) is a potent inhibitor of cell fusion caused by the SARSCoV‐2
spike (S) glycoprotein warranting further evaluation as an antiviral against COVID‐19 infections
5/14/2020 Novel ACE2-Ind. Carbohydrate-Binding of SARS-CoV-2 Spike Protein to Host Lectins and Lung Microbiota
6/29/2020 Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in
patients with hyperinflammation
9/9/2020 Cross-reactivity of SARS-CoV-2 with HIV chemiluminescent assay leading to false-positive results
3/5/2021 Broad phenotypic alterations & potential dysf. of lymphocytes in ind. clinically recovered from COVID-19
7/16/2021 The mechanism behind flaring/triggering of autoimmunity disorders associated with COVID-19

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12/20/2021 Role of the T cell vitamin D receptor in severe COVID-19
12/21/2021 How Does SARS-CoV-2 Affect the Brain and Its Implications for the Vaccines Currently in Use
1/22/2022 T cell apoptosis characterizes severe Covid-19 disease
3/11/2022 ACE2-independent infection of T lymphocytes by SARS-CoV-2
4/15/2022 Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and
MicroRNAs
4/7/2022 New generation of cancer-preventing vaccines could wipe out tumors before they form
Investigations
1/27/2020 Coronavirus Exposed, Part 1: Communist Coverup, or Pandemic Bioweapon of Mass Destruction?
1/28/2020 Bats, Gene Editing and Bioweapons: Recent DARPA Experiments Raise Concerns Amid Coronavirus Outbreak
2/2/2020 Moderately Strong Confirmation of a Laboratory Origin of 2019-nCoV
2/10/2020 The spike glycoprotein of the new 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
2/15/2020 Coronavirus Origins: Anatomy of a Scientific Inference
4/22/2020 Lab-made? SARS-CoV-2 genealogy through the lens of gain-of-function research
5/2/2020 SARS-CoV-2 is well adapted for humans: What does this mean for re-emergence?
2/1/2021 Vector sequences in early WIV SRA sequencing data of SARS-CoV-2 inform on a potential large-scale security
breach at the beginning of the COVID-19 pandemic
2/4/2021 Safety and security concerns regarding transmissible vaccines
2/17/2021 Another Potential Covid-19 Lab Leak Clue
3/16/2021 Neutralising antibody escape of SARS‐CoV‐2 spike protein: Risk assessment for antibody‐based Covid‐19
therapeutics and vaccines
3/18/2021 Letter from House Republicans to NIH Director Francis Collins seeking to advance an independent, scientific
investigation into the origins of the COVID-19 pandemic
6/29/2021 House Republican Hearing on COVID-19 Origin
7/3/2021 CONTAMINATION OR VACCINE RESEARCH? RNA Sequencing data of early COVID-19 patient samples
show abnormal presence of vectorized H7N9 hemagglutinin segment | Zenodo
7/22/2021 Who Watches the Watchmen? - Fauci's 'noble lie,' exposed
7/23/2021 Viral infection and transmission in a large, well-traced outbreak caused by the SARS-CoV-2 Delta variant
8/6/2021 SARS-CoV-2 spike and its adaptable furin cleavage site
10/1/2021 Global Diversification and Distribution of Coronaviruses With Furin Cleavage Sites
10/19/2021 Rapid Proliferation of Pandemic Research: Implications for Dual-Use Risks
10/21/2021 EcoHealth Alliance Conducted Risky Experiments on MERS Virus in China
10/26/2021 EcoHealth letter of clarification to Tabak & the NIH
10/27/2021 2021.10.27-Letter-to-NIH - House Energy & Commerce Committee
10/27/2021 In Major Shift, NIH Admits Funding Risky Virus Research in Wuhan
11/17/2021 Automated discovery of noncovalent inhibitors of SARS-CoV-2 main protease by consensus Deep Docking of 40
billion small molecules
12/14/2021 The seminal paper from the WIV claiming SARS-CoV-2 probably originated in bats appears to contain a
contrived specimen...and the signature of laboratory-derived synthetic biology
11/1/2021 SARS-CoV-2's closest relative, RaTG13, was generated from a bat transcriptome not a fecal swab: implications
for the origin of COVID-19
11/3/2021 NIH Officials Worked With EcoHealth Alliance to Evade Restrictions on Coronavirus Experiments
11/12/2021 Emergence of the Spike Furin Cleavage Site in SARS-CoV-2
12/23/2021 Unique SARS-CoV-2 variant found in public sequence data of Antarctic soil samples collected in 2018 & 2019
12/31/2021 Joe Rogan Experience #1757 Transcript - Robert Malone
1/10/2022 USMC IG's whistleblower report: SARS-CoV-2 Origins Investigation with US Government Program
Undisclosed Document Analysis
1/12/2022 House Energy & Commerce Committee letter to NIH, January 2022
4/5/2022 House E&C Committee - 2nd letter to Lawrence Tabak, acting NIH director, concerning Daszak & EHA

The Myth of the Blind Watchmaker – Topical Bibliography C. H. Rixey
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References
[in chronological order]
Montagnier, Luc et al. Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for AIDS.
Science, 5/20/1983.
Montagnier, Luc et al. A new type of retrovirus isolated from patients presenting with lymphadenopathy
& AIDS: Structural and antigenic relatedness with equine infectious anaemia virus. Science, 3/2/1984.
Gallo, Robert et al. Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-
III) from Patients with AIDS and Pre-AIDS. Science, 5/4/1984.
Wain-Hobson, Simon et al. Nucleotide sequence of the AIDS virus, LAV: Cell. Cell, 1/1/1985.
Gallaher, William. Detection of a fusion peptide sequence in the transmembrane protein of human
immunodeficiency virus. Cell, 7/31/1987.
Binley, James et al. A Recombinant HIV-1 Envelope Glycoprotein Complex Stabilized by an
Intermolecular Disulfide Bond between the gp120 and gp41 Subunits Is an Antigenic Mimic of the
Trimeric Virion-Associated Structure. Journal of Virology, 1/15/2000.
Vita, Claudio & Martin, Loic et al. Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes
cryptic neutralization epitopes. Nature Biotechnology, 12/16/2002.
Pohlmann, Stefan et al. Differential N-Linked Glycosylation of HIV & Ebola Virus Envelope
Glycoproteins Modulates Interactions with DC-SIGN and DC-SIGNR. Journal of Virology, 1/15/2003.
Peiris, JSM et al. Coronavirus as the causative agent of Severe Acute Respiratory Syndrome. The Lancet,
4/8/2003.
Gallaher, William & Garry, Robert. Model of the pre-insertion region of the spike (S2) fusion
glycoprotein of the human SARS coronavirus: implications for antiviral therapeutics. Virology
[Archived], 5/1/2003.
Yossef Kliger & Erez Levanon. Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-
SARS strategy. BMC Microbiology, 6/1/2003.
Su, Steven et al. DC-SIGN Binds to HIV-1 Glycoprotein 120 in a Distinct but Overlapping Fashion
Compared with ICAM-2 and ICAM-3. Journal of Biological Chemistry, 2/16/2004.
Redfield, Robert et al. Synthetic Bivalent CD4-Mimetic Miniproteins Show Enhanced Anti-HIV Activity
over the Monovalent Miniprotein. Bioconjugate Chemistry, 4/16/2004.
Zhang, Xue Wu & Yap, Yee Leng. Structural similarity between HIV-1 gp41 and SARS-CoV S2 proteins
suggests an analogous membrane fusion mechanism. Journal of Molecular Structure: THEOCHEM,
5/1/2004.
McMahon, Stephanie et al. Hypoxia-enhanced Expression of the Proprotein Convertase Furin Is Mediated
by Hypoxia-inducible Factor-1. Journal of Biological Chemistry, 12/14/2004.

The Myth of the Blind Watchmaker – Topical Bibliography C. H. Rixey
P a g e 7 | 18
Baric, Ralph & Sims, AC. Development of Mouse Hepatitis Virus and SARS-CoV Infectious cDNA
Constructs. Coronavirus Replication & Reverse Genetics, 1/1/2005.
Huang, Chin Chin et al. Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus
gp120 crystal structures, molecular mimicry, and neutralization breadth. Structure, 5/13/2005.
Beddows, Simon et al. Evaluating the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of
the envelope glycoprotein complex of HIV-1. Journal of Virology, 7/1/2005.
Michael Farzan & Fang Li. Structure of SARS Coronavirus Spike Receptor-Binding Domain Complexed
with Receptor. Science, 9/16/2005.
Shi, Zheng-Li & Daszak, Peter et al. Bats are Natural Reservoirs of SARS-like Coronaviruses. Science,
10/28/2005.
Gallaher, William & Garry, Robert et al. Inhibition of SARS-associated CoV infectivity by peptides
analogous to the viral spike protein. Virus Research 120, 1-2., 4/12/2006.
Huang, Qiuying et al. Preparation of a Chimeric Armored RNA as a Versatile Calibrator for Multiple
Virus Assays. Clinical Chemistry, 7/1/2006.
Follis, Kathryn et al. Furin cleavage of the SARS coronavirus spike glycoprotein enhances cell–cell
fusion but does not affect virion entry. Virology, 7/5/2006.
Shi, Zheng-Li & Daszak, Peter et al. Review of bats & SARS. Emerging Infectious Diseases, 12/12/2006.
Baric, Ralph. Synthetic Viral Genomics: Risks & Benefits for Science & Society. Working Papers for
Synthetic Genomics (39-81), 1/1/2007.
Baric, Ralph et al. A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
PLoS Pathogens, 1/3/2007.
Pohlmann, Stefan & Jiang, Shibo et al. Discovery and Optimization of a Natural HIV-1 Entry Inhibitor
Targeting the gp41 Fusion Peptide. Cell, 4/20/2007.
Shi, Zheng-Li et al. Difference in Receptor Usage between Severe Acute Respiratory Syndrome (SARS)
Coronavirus and SARS-Like Coronavirus of Bat Origin. Journal of Virology, 12/12/2007.
Baric, Ralph et al. Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in
mice. PNAS, 11/26/2008.
White, Judith et al. Structures and Mechanisms of Viral Membrane Fusion Proteins. Critical Reviews in
Biochemistry & Molecular Biology, 5/1/2009.
Yu, Bin et al. Protease Cleavage Sites in HIV-1 gp120 Recognized by Antigen Processing Enzymes Are
Conserved and Located at Receptor Binding Sites. Journal of Virology, 2/1/2010.
Baric, Ralph & Graham, Barney. Recombination, reservoirs, and the modular spike: mechanisms of
coronavirus cross-species transmission. Journal of Virology, 4/1/2010.

The Myth of the Blind Watchmaker – Topical Bibliography C. H. Rixey
P a g e 8 | 18
Pohlmann, Stefan et al. TMPRSS2 and TMPRSS4 facilitate trypsin-independent spread of influenza virus
in Caco-2 cells. Journal of Virology, 7/14/2010.
Pohlmann, Stefan et al. Peptide-based inhibitors of the HIV envelope protein and other class I viral fusion
proteins. Current Pharmaceutical Design, 12/1/2010.
Arsenault, Dominique et al. Hypoxia enhances cancer cell invasion through relocalization of the
proprotein convertase furin from the trans‐golgi network to the cell surface. Journal of Cellular
Physiology, 4/18/2011.
Chen, Weizao et al. Engineered Single Human CD4 Domains as Potent HIV-1 Inhibitors and
Components of Vaccine Immunogens. Journal of Virology, 8/17/2011.
Shi, Zheng-Li et al. Bat SARS-like coronavirus ORF3b homologues display different interferon
antagonist activities. Journal of General Virology, 10/18/2011.
Mascola, John & Kwong, Peter. A short segment of the HIV-1 gp120 V1/V2 region is a major
determinant of resistance to V1/V2 neutralizing antibodies. Journal of Virology, 5/23/2012.
Chong, Huihui et al. Discovery of Critical Residues for Viral Entry and Inhibition through Structural
Insight of HIV-1 Fusion Inhibitor CP621–652. Journal of Biological Chemistry, 6/1/2012.
Duerr, Ann et al. Extended Follow-up Confirms Early Vaccine-Enhanced Risk of HIV Acquisition and
Demonstrates Waning Effect Over Time Among Participants in a Randomized Trial of Recombinant
Adenovirus HIV Vaccine. The Journal of Infectious Diseases, 7/15/2012.
Fouchier, Ron et al. Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia. New
England Journal of Medicine, 11/8/2012.
Jiang, Shibo et al. A bivalent recombinant protein inactivates HIV-1 by targeting the gp41 prehairpin
fusion intermediate induced by CD4 D1D2 domains. Retrovirology, 12/7/2012.
Jiang, Shibo et al. HIV-1 Fusion Is Blocked through Binding of GB Virus C E2D Peptides to the HIV-1
gp41 Disulfide Loop. PLOS, 1/22/2013.
Perlman, Stanley & Gallagher, Tom. Broad reception for coronavirus. Nature, 3/13/2013.
Shi, Zheng-Li et al. Identification of Immunogenic Determinants of the Spike Protein of SARS-like
Coronavirus. Virologica Sinica, 4/28/2013.
Fauci, Anthony. Research on Highly Pathogenic H5N1 Influenza Virus: The Way Forward. mBio,
5/1/2013.
Shi, Zheng-Li et al. Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2
receptor. Nature, 11/28/2013.
Chong, Huihui et al. Design of a highly potent HIV-1 fusion inhibitor targeting t.... AIDS, 1/2/2015.
Shi, Zheng-Li, Baric, Ralph & Li, Fang et al. Two Mutations Were Critical for Bat-to-Human
Transmission of Middle East Respiratory Syndrome Coronavirus. Journal of Virology, 6/10/2015.

The Myth of the Blind Watchmaker – Topical Bibliography C. H. Rixey
P a g e 9 | 18
Epstein, Robert et al. The search engine manipulation effect (SEME) and its possible impact on the
outcomes of elections. PNAS, 8/4/2015.
Shi, Zheng-Li et al. A SARS-like cluster of circulating bat coronaviruses shows potential for human
emergence. Nature Medicine, 11/9/2015.
Baric, Ralph et al. SARS-like WIV1-CoV poised for human emergence. PNAS, 1/20/2016.
Shi, Zheng-Li et al. Coexistence of multiple coronaviruses in several bat colonies in an abandoned
mineshaft. Virologica Sinica, 1/22/2016.
Chong, Huihui et al. Development of potent and long-acting HIV-1 fusion inhibitor... . AIDS, 5/15/2016.
Qian, Yi-Wen et al. HIV-1 gp120 Glycoprotein Interacting with Dendritic Cell-specific Intercellular
Adhesion Molecule 3-grabbing Non-integrin (DC-SIGN) Down-Regulates Tight Junction Proteins to
Disrupt the Blood Retinal Barrier and Increase Its Permeability. The Journal of Biological Chemistry,
10/28/2016.
OSTP. Recommended Policy Guidance for Potential Pandemic Pathogen Care and Oversight. White
House Archives, 1/9/2017.
Shi, Zheng-Li et al. Discovery of a rich gene pool. PLoS Pathogens, 2/1/2017.
Chong, Huihui et al. A Lipopeptide HIV-1/2 Fusion Inhibitor with Highly Potent In Vitro, Ex Vivo, and
In Vivo Antiviral Activity . Journal of Virology, 5/12/2017.
Mascola, John et al. Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and
BMS-626529. Nature Chemical Biology, 8/21/2017.
Corbett, Kizzmekia et al. Immunogenicity and structures of a rationally designed prefusion MERS-CoV
spike antigen. PNAS, 8/29/2017.
Shountz, Tony et al. Immunological Control of Viral Infections in Bats and the Emergence of Viruses
Highly Pathogenic to Humans. Frontiers in Immunology, 9/11/2017.
Shi, Zheng-Li & Daszak, Peter et al. Serological Evidence of Bat SARS-Related Coronavirus Infection in
Humans, China . Virologica Sinica, 3/2/2018.
Sefferlin, Alexandra. Controversial HIV Researcher Robert Redfield Is CDC Director. Time, 3/22/2018.
Shi, Zheng-Li & Daszak, Peter et al. Fatal swine acute diarrhoea syndrome caused by an HKU2-related
coronavirus of bat origin.
Nature, 4/4/2018.
Mascola, John & Kwong, Peter. HIV-1 Vaccines Based on Antibody Identification, B Cell Ontogeny, and
Epitope Structure. Immunity, 5/15/2018.
Shi, Zheng-Li et al. Discovery of Novel Bat Coronaviruses in South China that use the Same Receptor as
MERS-CoV. Journal of Virology, 7/1/2018.

The Myth of the Blind Watchmaker – Topical Bibliography C. H. Rixey
P a g e 10 | 18
Graham, Barney & Sullivan, Nancy. Emerging viral diseases from a vaccinology perspective: preparing
for the next pandemic.
Nature Immunology, 12/14/2018.
Drosten, Christian, Graham, Barney & Pohlmann, Stefan et al. Mutations in the Spike Protein of MERS-
CoV Transmitted in Korea Increase Resistance to Antibody-Mediated Neutralization. Journal of
Virology, 1/4/2019.
Shi, Zheng-Li et al. Origin and evolution of pathogenic coronaviruses. Nature Reviews: Microbiology,
3/17/2019.
Xia, Shuai et al. A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus
spike. Science Advances, 4/10/2019.
Brouwer, Philip et al. Presentation of HIV-1 envelope glycoprotein trimers on diver…. Current Opinion
in HIV & AIDS, 7/1/2019.
Shi, Zheng-Li et al. Discovery of Bat CoV via Surveillance & Probe Capture-Based Next-Gen
Sequencing. MSphere [American Society for Microbiology], 11/6/2019.
Baric, Ralph et al. Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection. Journal of
Virology, 12/4/2019.
Shi, Zheng-Li et al. Molecular mechanism for antibody-dependent enhancement of coronavirus entry.
Journal of Virology, 12/11/2019.
National Institutes of Health . NIH-Moderna-Confidential Agreements. FOIA Documents - Judicial
Watch, 12/12/2019.
Shi, Zheng-Li & Jiang, SD et al.. An emerging coronavirus causing pneumonia outbreak in Wuhan,
China: calling for developing therapeutic and prophylactic strategies. Emerging Microbes & Infections,
1/21/2020.
Li Xin et al. A furin cleavage site was discovered in the spike protein of the 2019 nCoV. Chinese Journal
of Bioinformatics, 1/21/2020.
Holmes, Edward et al. Complete genome characterisation of a novel coronavirus associated with severe
human respiratory disease in Wuhan, China. Research Gate, 1/23/2020.
Shi, Zheng-Li et al. Discovery of a novel coronavirus associated with the recent pneumonia outbreak in
humans and its potential bat origin. Nature, 1/23/2020.
Bond, Adrian. Coronavirus Exposed, Part 1: Communist Coverup, or Pandemic Bioweapon of Mass
Destruction?. Medium, 1/27/2020.
Webb, Whitney. Bats, Gene Editing and Bioweapons: Recent DARPA Experiments Raise Concerns
Amid Coronavirus Outbreak (thelastamericanvagabond.com). The Last American Vagabond, 1/28/2020.
Lu, Hongzhou. Drug treatment options for the 2019-nCoV. BioScience Trends, 1/28/2020.

The Myth of the Blind Watchmaker – Topical Bibliography C. H. Rixey
P a g e 11 | 18
Pradhan, Prashant et al. Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1
gp120 and Gag. bioRxiv, 1/30/2020.
Lu, RZ et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for
virus origins and receptor binding. The Lancet, 1/30/2020.
Karesh, William et al. Origins of MERS-CoV, and lessons for 2019-nCoV. The Lancet Planetary Health,
1/30/2020.
Drosten, Christian et al. The continuing 2019-nCoV epidemic threat of novel coronaviruses to global
health - The latest outbreak in Wuhan, China. International Journal of Infectious Diseases, 2/1/2020.
Gallaher, William & Gallaher, Andrew. Analysis of Wuhan Coronavirus: déjà vu [findings on 1/29, 1st
edition on 2/1]. Virological.org, 2/1/2020.
Shi, Zheng-Li et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin.
Nature, 2/1/2020.
Oransky, Ivan & Marcus, Adam. Quick retraction of coronavirus paper was good moment for science.
StatNews, 2/2/2020.
Weiler, James Lyons. Moderately Strong Confirmation of a Laboratory Origin of 2019-nCoV .
JamesLyonsWeiler.com, 2/2/2020.
Drosten, Christian & Wang, Linfa et al. Accelerated viral dynamics in bat cell lines, with implications for
zoonotic emergence. eLife, 2/3/2020.
Chuan Xiao et al. HIV-1 did not contribute to the 2019-nCoV genome. Emerging Microbes & Infections,
2/4/2020.
Gallaher, William. Tackling Rumors of a Suspicious Origin of nCoV2019 - SARS-CoV-2 coronavirus.
Virological.org, 2/6/2020.
Daszak, Baric, Andersen, Perlman. NASEM Response to OSTP re Coronavirus_February 6, 2020. OSTP
site, 2/7/2020.
Coutard, B. et al. The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like
cleavage site absent in CoV of the same clade. Antiviral Research, 2/10/2020.
Shi, Zheng-Li et al. Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in
spike protein. Cellular & Molecular Immunology, 2/11/2020.
Saif, Linda, Weiss, Susan, Su, Lishan & Liu, Shan-Lu. No credible evidence supporting claims of the
laboratory engineering of SARS-CoV-2. Emerging Microbes & Infections, 2/13/2020.
Shi, Zheng-Li et al. The First Disease X is Caused by a Highly Transmissible Acute Respiratory
Syndrome Coronavirus. Virologica Sinica, 2/14/2020.
Weiler, James Lyons. Coronavirus Origins: Anatomy of a Scientific Inference. JamesLyonsWeiler.com,
2/15/2020.

The Myth of the Blind Watchmaker – Topical Bibliography C. H. Rixey
P a g e 12 | 18
Andersen, Kristian et al. The proximal origin of SARS-CoV-2. Nature Medicine, 2/16/2020.
Shi, Zheng-Li et al. Molecular and serological investigation of 2019-nCoV infected patients: implication
of multiple shedding routes. Emerging Microbes & Infections, 2/17/2020.
Hao Pei et al. Is SARS-CoV-2 originated from laboratory? A rebuttal to the claim of formation via
laboratory recombination. Emerging Microbes & Infections, 2/19/2020.
Daszak, Peter et al. Statement in support of the scientists, public health professionals, and medical
professionals of China combatting COVID-19. The Lancet, 2/19/2020.
Malone, Robert & Ricke, Darrell. Medical Countermeasures Analysis of 2019-nCoV and Vaccine Risks
for Antibody-Dependent Enhancement (ADE) by Darrell Ricke, Robert W. Malone :: SSRN. SSRN,
3/2/2020.
Perez, Jean-Claude. WUHAN COVID-19 SYNTHETIC ORIGINS AND EVOLUTION. Zenodo,
3/23/2020.
Shi, Zheng-Li et al. Inhibition of SARS-CoV-2 infection by a highly potent pan-CoV fusion inhibitor
targeting its spike protein that harbors a high capacity to mediate membrane fusion. Cell Research,
3/30/2020.
Fakher, Shima et al. The Role of Autophagy in Respiratory Complications of COVID-19. Shiraz E-
Medical Journal, 4/3/2020.
Wang, Jiong & Zand, Martin. The potential for antibody-dependent enhancement of SARS-CoV-2
infection: Translational implications for vaccine development. Journal of Clinical & Translational
Science, 4/13/2020.
Deigin, Yuri. Lab-made? SARS-CoV-2 genealogy through the lens of gain-of-function research. Medium,
4/22/2020.
Perez, Jean-Claude & Montagnier, Luc. COVID-19, SARS and Bats Coronaviruses Genomes Unexpected
Exogeneous RNA Sequences. OSF Pre-Prints, 4/25/2020.
Arumugham, Vinu. Root cause of COVID-19? Biotechnology's dirty secret: Contamination.
Bioinformatics evidence demonstrates that SARS-CoV-2 was created in a laboratory…. Zenodo,
4/25/2020.
Pohlmann, Stefan et al. A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for
Infection of Human Lung Cells. Molecular Cell, 5/1/2020.
Zhan, Shing Hei & Chan, Alina. SARS-CoV-2 is well adapted for humans: What does this mean for re-
emergence?. bioRxiv, 5/2/2020.
Musarrat, Farhana et al. The anti‐HIV drug nelfinavir mesylate (Viracept) is a potent inhibitor of cell
fusion caused by the SARSCoV‐2 spike (S) glycoprotein warranting further evaluation as an antiviral
against COVID‐19 infections. Journal of Medical Virology, 5/6/2020.
Chiodo, Fabrizio et al. Novel ACE2-Independent Carbohydrate-Binding of SARS-CoV-2 Spike Protein to
Host Lectins and Lung Microbiota. bioRxiv, 5/14/2020.

The Myth of the Blind Watchmaker – Topical Bibliography C. H. Rixey
P a g e 13 | 18
Anonymous. Guoke Faji 2019/236 and the SARS-CoV-2 Outbreak . Telegraph, 5/15/2020.
Whitaker, Gary et al. Coronavirus membrane fusion mechanism offers a potential target for antiviral
development. Antiviral Research, 6/1/2020.
Sørensen, Birger, Dalgleish, Angus & Susrud, Andres. Biovacc-19: A candidate vaccine…... QRB
Discovery, 6/2/2020.
Bahar, Ivet et al. Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed
TCR repertoire in patients with hyperinflammation . PNAS, 6/29/2020.
Dalgleish, Angus et al. The evidence which suggests that this is no naturally evolved virus. Minerva,
7/2/2020.
Perez, Jean-Claude & Montagnier, Luc. HIV man-manipulated coronavirus genome evolution trends.
Zenodo, 8/2/2020.
Castro-Chavez, Fernando. Anticovidian v.2 COVID-19: Hypothesis of the Lab Origin Versus a Zoonotic
Event which can also be of a Lab Origin. Global Journals, 8/5/2020.
Michel Thepaut et al. DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-
infection and can be inhibited by a glycomimetic antagonist. bioRxiv, 8/10/2020.
Yong, Shin Jie. The Mutations that Caused Covid-19 Reinfection Explained. Medium, 8/28/2020.
Laumaea, Annemarie et al. Opening the HIV envelope: potential of CD4 mimics as multifunctional HIV
entry inhibitors. Current Opinion in HIV & AIDS, 9/1/2020.
Farrar, Jeremy & Holmes, Edward et al. COVID-19 futures: a framework for exploring medium and long-
term impacts. SSRN, 9/3/2020.
Tan, Shaun et al. Cross-reactivity of SARS-CoV-2 with HIV chemiluminescent assay leading to false-
positive results. British Medical Journal, 9/9/2020.
Cheng, Mary Hongying. Superantigenic character of an insert unique to SARS-CoV-2 spike supported by
skewed TCR repertoire in patients with hyperinflammation | PNAS. PNAS, 9/28/2020.
Wang, Qian et al. Stabilized diverse HIV-1 envelope trimers for vaccine design. Emerging Microbes &
Infections, 12/9/2020.
Jiang, Shibo et al. Protein- and Peptide-Based Virus Inactivators: Inactivating Viruses Before Their Entry
Into Cells. Frontiers in Microbiology, 12/9/2020.
Outlaw, Viktor et al. Inhibition of Coronavirus Entry In Vitro and Ex Vivo by a Lipid-Conjugated Peptide
Derived from the SARS-CoV-2 Spike Glycoprotein HRC Domain. mBio, 12/11/2020.
Wang, Xinling et al. Pan-coronavirus fusion inhibitors as the hope for today and tomorrow. Protein &
Cell, 1/9/2021.

The Myth of the Blind Watchmaker – Topical Bibliography C. H. Rixey
P a g e 14 | 18
Ahmedi, Khadijeh et al. Enfuvirtide, an HIV-1 fusion inhibitor peptide, can act as a potent SARS-CoV-2
fusion inhibitor: an in silico drug repurposing study. Journal of Biomolecular Structure & Dynamics,
1/13/2021.
Zhang, Daoyu. Vector sequences in early WIV SRA sequencing data of SARS-CoV-2 inform on a
potential large-scale security breach at the beginning of the COVID-19 pandemic. Zenodo, 2/1/2021.
Esvelt, Kevin et al. Safety and security concerns regarding transmissible vaccines. Nature Ecology &
Evolution, 2/4/2021.
Editorial Board. Another Potential Covid-19 Lab Leak Clue. The Wall Street Journal, 2/17/2021.
https://www.wsj.com/articles/another-potential-covid-19-lab-leak-clue-china-11644615472
Yang, Jingyi et al. Broad phenotypic alterations and potential dysfunction of lymphocytes in individuals
clinically recovered from COVID-19. Journal of Cell & Molecular Biology, 3/5/2021.
Focosi, Daniele & Maggi, Fabrizio. Neutralising antibody escape of SARS‐CoV‐2 spike protein: Risk
assessment for antibody‐based Covid‐19 therapeutics and vaccines. Reviews in Medical Virology,
3/16/2021.
McMorris-Rodgers, Cathy et al. Letter from House Republicans to NIH Director Francis Collins seeking
to advance an independent, scientific investigation into the origins of the COVID-19 pandemic. House
E&C Committee, 3/18/2021.
Yu, Danwei et al. Pan-CoV fusion inhibitors possess potent inhibitory activity against HIV-1, HIV-2, and
SIV. Emerging Microbes & Infections, 4/13/2021.
Xia, Shuai et al. Supercoiling Structure-Based Design of a Trimeric Coiled-Coil Peptide with High
Potency against HIV-1 and Human β-Coronavirus Infection. Journal of Medical Chemistry, 4/30/2021.
House Republican caucus. House Republican Hearing on COVID-19 Origin. US House of
Representatives, 6/29/2021.
Fleming, Richard. Dr. Richard Fleming discusses the HIV inserts. YouTube, 7/1/2021.
Jones, Steven. CONTAMINATION OR VACCINE RESEARCH? RNA Sequencing data of early
COVID-19 patient samples show abnormal presence of vectorized H7N9 hemagglutinin segment |
Zenodo. Zenodo, 7/3/2021.
Fleming, Richard. BASES2021 SARS CoVd2 Gain of Function Research Violations of Law. Youtube,
7/15/2021.
Uversky, Vladimir et al. The mechanism behind flaring/triggering of autoimmunity disorders associated
with COVID-19. Autoimmunity Reviews, 7/16/2021.
Rixey, Charles. Who Watches the Watchmen? - Fauci's 'noble lie,' exposed. Prometheus Shrugged,
7/22/2021.
Li, Baisheng et al. Viral infection and transmission in a large, well-traced outbreak caused by the SARS-
CoV-2 Delta variant. Nature Communications, 7/23/2021.

The Myth of the Blind Watchmaker – Topical Bibliography C. H. Rixey
P a g e 15 | 18
Jiang, Shibo et al. Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and
its variants with preclinical evaluation. Signal Transduction & Targeted Therapy, 7/29/2021.
Whitaker, Gary et al. SARS-CoV-2 spike and its adaptable furin cleavage site. The Lancet Microbe,
8/6/2021.
Suryanarayanan, Sainath. Fang-Li-emails.pdf. US Right-to-Know, 8/14/2021.
Zhang, Daoyu. Proposal and protocol for the construction of pEF1-ACE2-IGG2-SMAR vector for gene
therapy of SARS-CoV-2. Zenodo, 8/15/2021.
Wain-Hobson, Simon. A Lab Accident would be the Chernobyl of Biology. Le Point, 9/10/2021.
Curelli, Francesca et al. Discovery of Highly Potent Fusion Inhibitors with Potential Pan-CoV Activity
That Effectively Inhibit Major COVID-19 Variants of Concern (VOCs) in Pseudovirus-Based Assays.
Viruses, 9/17/2021.
DRASTIC. PREEMPT - DRASTIC'S Analysis of the DEFUSE Rejection Letter. DRASTIC, 9/20/2021.
DRASTIC. PREEMPT - DRASTIC's Analysis of the PREEMPT/DEFUSE Proposal. DRASTIC,
9/20/2021.
Martensen, Chris. Odds increase that SARS-CoV-2 was lab-made. Peak Prosperity/YouTube, 9/21/2021.
Wade, Nicholas. New Routes to Making Covid-19 In The Lab. Medium, 9/23/2021.
Gallagher, Mike. Why DRASTIC's PREEMPT release is so important. US House of Representatives,
9/23/2021.
Brand, Russell. Uh oh…The Wuhan Lab Leak Debate just got even messier…. YouTube, 9/23/2021.
Lerner, Sharon & Hibbett, Maia. Leaked Grant Proposal Details High-Risk Coronavirus Research. The
Intercept, 9/23/2021.
Markson, Sharri. What Really Happened in Wuhan: A virus like no other. Harper-Collins, 9/27/2021.
Perween, Reshma et al. The SARS CoV-2 spike directed non-neutralizing polyclonal antibodies cross-
react with HIV-1 gp41. International Immunopharmacology, 9/28/2021.
Xiaotong Lu et al. Global Diversification and Distribution of Coronaviruses With Furin Cleavage Sites.
Frontiers in Microbiology, 10/1/2021.
Wain-Hobson, Simon. Simon Wain-Hobson's analysis of the DEFUSE proposal. DRASTIC, 10/4/2021.
Wain-Hobson, Simon. Simon Wain-Hobson's annotated version of the DEFUSE proposal. DRASTIC,
10/4/2021.
Musunuri, Sriharshita et al. Rapid Proliferation of Pandemic Research: Implications for Dual-Use Risks.
mBio, 10/19/2021.

The Myth of the Blind Watchmaker – Topical Bibliography C. H. Rixey
P a g e 16 | 18
Lerner, Sharon & Hibbett, Maia. EcoHealth Alliance Conducted Risky Experiments on MERS Virus in
China. The Intercept, 10/21/2021.
Daszak, Peter. EcoHealth letter of clarification to Tabak & the NIH. EcoHealth Alliance, 10/26/2021.
Energy & Commerce Com.. 2021.10.27-Letter-to-NIH - House Energy & Commerce Committee. US
House of Representatives, 10/27/2021.
Eban, Katherine. In Major Shift, NIH Admits Funding Risky Virus Research in Wuhan. Vanity Fair,
10/27/2021.
Massey, Steven. SARS-CoV-2's closest relative, RaTG13, was generated from a bat transcriptome not a
fecal swab: implications for the origin of COVID-19. Research Gate, 11/1/2021.
Hvistendahl, Mara & Lerner, Sharon. NIH Officials Worked With EcoHealth Alliance to Evade
Restrictions on Coronavirus Experiments. The Intercept, 11/3/2021.
Zhan, Shing Hei & Chan, Alina. Emergence of the Spike Furin Cleavage Site in SARS-CoV-2. Molecular
Biology & Evolution, 11/12/2021.
Gentile, Francesco et al. Automated discovery of noncovalent inhibitors of SARS-CoV-2 main protease
by consensus Deep Docking of 40 billion small molecules. Chemical Science, 11/17/2021.
Derking, Ronald & Sanders, Rogier. Structure-guided envelope trimer design in HIV-1 vaccine
development: a narrative review. Journal of the International AIDS Society, 11/24/2021.
Massey, Steven. Host Manipulation Mechanisms of SARS-CoV-2. Acta Biotheoretica, 12/13/2021.
Quay, Steven. The seminal paper from the WIV claiming SARS-CoV-2 probably originated in bats
appears to contain a contrived specimen...and the signature of laboratory-derived synthetic biology.
Zenodo, 12/14/2021.
Menachery, Vineet et al. QTQTN motif upstream of the furin-cleavage site plays key role in SARS-CoV-
2 infection and pathogenesis. bioRxiv, 12/17/2021.
Kolls, Jay & Garry, Robert. Role of the T cell vitamin D receptor in severe COVID-19. Nature
Immunology, 12/20/2021.
Oldfield, Philip et al. How Does SARS-CoV-2 Affect the Brain and Its Implications for the Vaccines
Currently in Use. Vaccines, 12/21/2021.
Csabai, Istvan et al. Unique SARS-CoV-2 variant found in public sequence data of Antarctic soil samples
collected in 2018 & 2019. Research Square, 12/23/2021.
Syed, Ah Khan. How to BLAST your way to the truth about the origins of COVID-19. Substack,
12/28/2021.
Rogan, Joe & Malone, Robert. Joe Rogan Experience #1757 Transcript - Robert Malone. The Joe Rogan
Experience, 12/31/2021.

The Myth of the Blind Watchmaker – Topical Bibliography C. H. Rixey
P a g e 17 | 18
Curelli, Francesca et al. Discovery of Highly Potent Fusion Inhibitors with Potential Pan-CoV Activity
That Effectively Inhibit Major COVID-19 VOCs in Pseudovirus-Based Assays. Viruses, 12/31/2021.
Yue, Zhang et al. A second functional furin site in the SARS-CoV-2 spike protein. Emerging Microbes &
Infections, 1/4/2022.
Murphy, Joseph. USMC Inspector General's whistleblower report: SARS-CoV-2 Origins Investigation
with US Government Program Undisclosed Document Analysis. Project Veritas/DoD leak, 1/10/2022.
House E&C Committee. House Energy & Commerce Committee letter to NIH, January 2022. US House
of Representatives, 1/12/2022.
Andre, Sonia et al. T cell apoptosis characterizes severe Covid-19 disease. Nature Cell Death & Cell
Differentiation, 1/22/2022.
Qing, Xiong et al. Close Relatives of MERS-CoV in bats use ACE2 as their functional receptors
[NeoCoV]. bioRxiv, 1/25/2022.
Brufsky, Adam et al. MSH3 Homology and Potential Recombination Link to SARS-CoV-2 Furin
Cleavage Site. Frontiers in Virology, 2/21/2022.
Ledford, Heidi. Luc Montagnier (1932–2022) - Obituary. Nature, 3/4/2022.
Shi, Zheng-Li et al. ACE2-independent infection of T lymphocytes by SARS-CoV-2. Signal
Transduction & Targeted Therapy, 3/11/2022.
Mndal, Chandi et al. Combinatorial influence of environmental temperature, obesity and cholesterol on
SARS-CoV-2 infectivity. Nature Scientific Reports, 3/21/2022.
Puhl, Ana et al.. The Need for Speed and Efficiency: A Brief Review of Small Molecule Antivirals for
COVID-19. Frontiers in Drug Discovery, 3/30/2022.
Shi, Zheng-Li & Wolfe, Nathan et al. The Animal Origin of Major Human Infectious Diseases: What Can
Past Epidemics Teach Us About Preventing the Next Pandemic?. Zoonoses, 4/1/2022.
Cattaneo, Alberto Maria. Reviewing findings on the polypeptide sequence of the SARS-CoV-2 protein to
discuss the origins of the virus. Future Virology, 4/5/2022.
House E&C Committee. House E&C Committee - 2nd letter to Lawrence Tabak, acting NIH director,
concerning Daszak & EHA. US House of Representatives, 4/5/2022.
Kaiser, Jocelyn. New generation of cancer-preventing vaccines could wipe out tumors before they form.
Science, 4/7/2022.
Syed, Ah Khan. Absolute proof: The Gp-120 sequences prove beyond all doubt that "COVID-19" was
man-made. Substack, 4/10/2022.
Xia, Shuai et al. Coronavirus Entry Inhibitors. Advances in Experimental Medicine & Biology, 4/11/2022.
Jiang, Shibo et al. Peptide-Based HIV Entry Inhibitors. Advances in Experimental Medicine & Biology,
4/13/2022.

The Myth of the Blind Watchmaker – Topical Bibliography C. H. Rixey
P a g e 18 | 18
Seneff, Stephanie et al. Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-
quadruplexes, exosomes, and MicroRNAs. Food & Chemical Toxicology, 4/15/2022.
Roncato, Rossana et al. Lipid rafts as viral entry routes and immune platforms: A double-edged sword in
SARS-CoV-2 infection?. Biochimica et Biophysica Acta, 6/1/2022.