This chapter summarizes the unique perspectives and contributions in this volume, to offer insights regarding search for meaning in life in a post-modern socio-cultural context. We suggest that instead of major overarching cultural schemes, institutions or narratives for meaning in life which were prominent and dominant in the past, such as religion, contemporary societies in the post-modern era offer a large variety of narratives, termed here 'master narratives of meaning'. Individuals adopt and adapt such narratives to fulfil their need for meaning in life and to have clarity and stability, and specifically to satisfy their need for comprehension, purpose and mattering. Exploring illustrative case studies within the Israeli scene, we identified several broad dimensions of the search for meaning that might be relevant in other cultures as well, such as, the mix and match quality of the narratives, the centrality of spirituality both within and outside established religions, the centrality of legitimation of a variety of narratives versus their de-legitimation and adoption of a rigid dogma, and a self-focused process versus the focus on belonging to a community or becoming a 'citizen of the world' with responsibility to make it a better place. These master narratives of meaning weave cultural characteristics and contextual imperatives with personal processes of meaning-making and appear to also highlight broader processes of search for meaning around the globe.