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Sys Rev Pharm 2020; 11(6): 733 741 A multifaceted review journal in the field of pharmacy Studying the Pharmaceutical; Elements and Bio- Effect of the Chamomile Plants as a Medicinal Plant

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In this research to measure the concentration of elements in the plant chamomile and effectiveness of these items on the biological processes of the human person and the benefits arising from this plant and plant use alternative chemicals used in the pharmaceutical industry Medicine it was measured elements (Fe, Cu, Zn, Pb, Cd) in three different ways depending the process used to reach the best results and to measure the concentration of the elements and compare them with each other. It has also been on the search study the effect of the measured concentrations of the elements on the Rights of the benefits and harms of health has also been studying the benefits of chamomile for humans and how to take advantage of it. And knowledge of the work of each of these elements with the last element association for the purpose of organizing its work within the human body in biological processes and their effectiveness in regulating vital biological processes. The concentration of elements in the chamomile plant was measured in this research and the effectiveness of these elements on human biological processes, the benefits of this plant, the use of plants as an alternative medicine for the chemicals used in the pharmaceutical industry, and elements (Fe, Cu, Zn, Pb, Cd) were measured in three different ways depending on the process used to achieve the best results and measure and compare their concentration Together. The research also examined the impact of the trickiness of measured elements on human health from harmful benefits and benefits, and the benefits of the human chamomile were studied and how it could be used. The working of each of these elements is linked to another element for the purpose of organizing their work within the human body is vital processes and their effectiveness in the organization of biological and biological processes.
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Sys Rev Pharm 2020; 11(6): 733 741
A multifaceted review journal in the field of pharmacy
E-ISSN 0976-2779 P-ISSN 0975-8453
733 Systematic Review Pharmacy Vol 11, Issue 6, 2020
Studying the Pharmaceutical; Elements and Bio-
Effect of the Chamomile Plants as a Medicinal Plant
Suaad Abd Al-Mahdi Abd Noor
University of Kufa, Faculty of Pharmacy, Iraq
E-mail: Suaad.toobi@uokufa.edu.iq
Article History: Submitted: 10.04.2020 Revised: 14.05.2020 Accepted: 22.06.2020
ABSTRACT
In this research to measure the concentration of elements in the plant
chamomile and effectiveness of these items on the biological
processes of the human person and the benefits arising from this
plant and plant use alternative chemicals used i n the pharmaceutical
industry Medicine it was measured elements (Fe, Cu, Zn, Pb, Cd) in
three different ways depending the process used to reach the best
results and to measure the concentration of the elements and
compare them with each other. It has also been on the search study
the effect of the measured concentrations of the elements on the
Rights of the benefits and harms of health has also been studying the
benefits of chamomile for humans and how to take advantage of it.
And knowledge of the work of each of these elements with the last
element ass ociation for the purpose of organizing its work within the
human body in biological processes and their effectiveness in
regulating vital biological processes. The concentration of elements in
the chamomile plant was mea sured in this research and the
effectiveness of these elements on h uman biological processes, the
benefits of this plant, the use of plants as an alternative medicine for
the chemicals used in the pharmaceutical industry, and elements (Fe,
Cu, Zn, Pb, Cd) were measured in three different ways depending on
the process used to achieve the best results and mea sure a nd
compare their concentration Together. The research also examined
the impact of the trickiness of measured elements on human health
from harmful benefits and benefits, and the benefits of the human
chamomile were studied and how it could be used. The working of
each of these elements is linked to another eleme nt for the purpose of
organizing their work within the human body is vital processes and
their effectiveness in the organization of biological and biological
processes.
Keywords: pharmaceutical; medicinal; chamomile plants; bioactive.
Correspondence:
Suaad Abd Al Mahdi Abd Noor
University of Kufa, Faculty of Pharmacy, Iraq
E-mail: suaad.toobi@uokufa.edu.iq
DOI: 10.31838/srp.2020.6.108
@Advanced Scientific Research. All rights reserved
INTRODUCTION
Chamomile of the most important and famous medicinal
plants and chamomile herbal around the plant with a height
of approximately (15-35 cm) Quick. Barmaid many
branching growths and blooming after (6-8) weeks of Grow
and leaves alternating Richer and fragmented into small
sections elongated linear and plant a distinctive refreshing
scent and flowers surrounding white interior and pipe
flowers and the color yellow. And knows chamomile
scientifically as (Matric aria chamomile), a wild-type, while
there is another type known as (Anthemisnobelis) and shape
different from the first type, and both contain the active
substances or influential part of the plant used chamomile
flowers blooming is chamomile of the most famous
medicinal plant absolutely native to the Orient and the Arab
Maghreb, Turkey and the Caucasus and all over Europe is
almost (Sarris, J; Panossian, et al.2011). Growing
chamomile plants in environments with fertile soil like some
kindergartens and water slopes of the mountains and in the
fields and on the edge of the valleys. Flowers Chamomile
contains a volatile oil up to another (1.5%) from the dry
flowers and extracted oil using a method of steam
distillation and oil chamomile means heavy strength gooey
color Blue freezes cooling in zero Celsius degree and it
smells known chamomile and most volatile oil Alpha
Basiabol contents (Alpha bisabolol) Baseball dioxide and A
(Bisabolol oxide A) and Baseball dioxide B (Bisabolol oxide
B) the active Ingredients found among the contents of the
oil are the substance (Alozulin) and are earning chamomile
impact heals. And properties they Olive as oil which
contains unsaturated fatty acids are many fast chemical
familiarity fusion materials and other uses for the
installation of such materials there are several medical uses
of chamomile, where previous studies show there are lists of
more than 100 diseases. Different chamomile which was
traditionally used to treat these diseases and heart disease
and blood vessels, colds and diarrhea in children, eczema
and gastrointestinal hemorrhagic cystitis, hemorrhoids, and
skin infections, insomnia, and heal wounds (Saller R,
Beschomer M, Hellenbrecht D, et al.1990, Janmejai K
Srivastava, et al.2011, Ahmed Gohar, Ahmed Zaki 2014).
Drowsiness or sedation and the ability to stimulate the
uterus must when be preparing herbal medicine to be
familiar with the experience and when you do not know
properly can lead to counterproductive because they interact
with other herbs and medicines were not informed of
chamomile (Ross SM.2008). The effect of chamomile in
treating thyroid disorders has also been studied (Elena Riza
,et al.2015). It has also found an effect of chamomile in
treating cancer (Shumacher M.; M. A.et al.1991). It has an
effect in treating diabetes (Rafraf M; et al.2015, Saira Khan,
Rahila Najam; et al.2014).
Practical part
The following are three different ways to get the
combination plant chamomile lotion with distilled water
and sampling them and measuring the concentrations of
elements (Fe, Cu, Zn, Pb, Cd) of the plant under study using
atomic absorption device.
1-The first way: Were taken in equal weights of the plant
chamomile with equal volumes of distilled water was mixing
water with plant chamomile was the mixture heated on a
regular basis and gradually using thermal controlled heater
on the temperature and took a sample of the mixture every
five temperatures starting from (30, 35,40,45,50, 55,......, 100)
° C were obtained (15) a sample. Where was painted
absorbance values against the concentration of the element.
Then the focus was drawn to the element versus
temperature values.
2-The second method: Distilled water was heated curb
boiling and then was added to the plant chamomile
mechanism and mix them together and then take samples of
Suaad Abd Al Mahdi Abd Noor / Studying the Pharmaceutical; Elements and Bio-Effect of the Chamomile Plants as a
Medicinal Plant
734 Systematic Review Pharmacy Vol 11, Issue 6, 2020
the mix after each period of (10 min.) (10, 20,30,40,50 min.)
And thus was obtained five a sample. Then it was painted
absorbance values versus concentration. And then draw the
focus of the component values versus time.
3 - The third way: It was taking a certain weight from a plant
chamomile with a given volume of distilled water and mix
with each other under normal conditions of temperature
without heating and left for a period of (24 hours) and after
the sample was taken from the mix was measured
proportions of the items in the plant under study. Drawing
was a focus for every element values. The use of samples
concentration using the unit of (ppm) and was also used
atomic absorption device for measuring the concentration
of elements (Fe, Cu, Zn, Pb, Cd) in the plant chamomile. As
has been the study of the effect of temperature on the
concentration of elements in the plant chamomile. As well
as the time factor.
RESULTS AND DISCUSSION
A study of the impact of concentrations of elements in the
chamomile plant on humans. And the effect of the change of
temperature and time on the concentration of each of them
in the plant.
Iron Element
Notes of figure (1) iron concentration in the chamomile
plant, where the highest concentration of it at a temperature
(55 ° C) within the first part of our way.
Figure 1: Shows the concentration of iron (Fe) in the plant chamomile varying degrees heat
Also, it studied the effect of changing times on the iron
concentration in the plant chamomile, as shown in Figure
(2) as it shows a better concentration of the element within
the second part of the modus operandi is after (30 min.)
after the addition of plant chamomile to boiling water.
Figure 2: Shows the concentration of iron (Fe) in the plant chamomile change time
Copper element
It is measured copper concentrations in plant chamomile, as
shown in Figure (3) where it was noted that the highest
concentration of copper was at a temperature (30 ° C(
0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0.8
0.9
1
0 5 10 15 20 25 30 35 40 45 50 55 60 65 70 75 80 85 90 95100105
(Fe) (Con.ppm)
Tem
Measuring the concentration of iron in the chamomile
plant
0
0.1
0.2
0.3
0.4
0.5
0.6
010 20 30 40 50 60
(Fe) (Con.ppm)
Time
Measuring the concentration of iron in the
chamomile plant
Suaad Abd Al Mahdi Abd Noor / Studying the Pharmaceutical; Elements and Bio-Effect of the Chamomile Plants as a
Medicinal Plant
735 Systematic Review Pharmacy Vol 11, Issue 6, 2020
Figure 3: Shows the concentration of copper (Cu) in the plant chamomile varying degrees heat
As for the impact of changing times on the copper concentration in the chamomile plant it was later (30 minutes) and at the
time (50 min.), as shown in Figure (4).
Figure 4: Shows the concentration of copper (Cu) in the plant chamomile change time
Zinc element
Is measured zinc concentration in the plant chamomile, as
shown in Fig. (5) where it was noted that the highest
percentage of the concentration of the element was at a
temperature (65 ° C).
Figure 5: Which shows the concentration of zinc (Zn) in the plant chamomile varying degrees heat
0
0.02
0.04
0.06
0.08
0.1
0.12
0.14
0.16
0 5 10 15 20 25 30 35 40 45 50 55 60 65 70 75 80 85 90 95100105
(Cu) (Con.ppm)
Tem.
Measuring the copper concentration in the
chamomile plant
0
0.02
0.04
0.06
0.08
0.1
0.12
0.14
0.16
0.18
010 20 30 40 50 60
(Cu) (Con.ppm)
Time
Measuring the copper concentration in the chamomile
plant
Suaad Abd Al Mahdi Abd Noor / Studying the Pharmaceutical; Elements and Bio-Effect of the Chamomile Plants as a
Medicinal Plant
736 Systematic Review Pharmacy Vol 11, Issue 6, 2020
As for the impact of changing times on the concentration of elements in the chamomile plant it was later (40 minutes) and at
the time (20 minutes). As shown in Figure (6).
Figure 6: Shows the concentration of zinc (Zn) in the plant chamomile change time
Lead element
Lead is measured element concentration in the plant
chamomile, as shown in Figure (7) where it was noted that
the highest concentration of the element in the chamomile
plant at a temperature (35 ° C).
Figure 7: Which shows the concentration of component lead (Pb) in the plant chamomile varying degrees heat
As for the impact of changing times on the concentration of lead element of the chamomile plant it was later (20 min.). As
shown in Figure (8).
Figure 8: Which shows the concentration of component lead (Pb) in the plant chamomile change time
0
2
4
6
8
10
12
010 20 30 40 50 60
(Zn) (Con.ppm)
Time
Measuring the concentration of zinc element in the
chamomile plant
0
0.05
0.1
0.15
0.2
0.25
0.3
0.35
0.4
0 5 10 15 20 25 30 35 40 45 50 55 60 65 70 75 80 85 90 95100105
(Pb) (Con.ppm)
Tem.
Measuring the concentration of lead element in the
chamomile plant
0
0.02
0.04
0.06
0.08
0.1
0.12
0.14
0.16
010 20 30 40 50 60
(Pb) (Con.ppm)
Time
Suaad Abd Al Mahdi Abd Noor / Studying the Pharmaceutical; Elements and Bio-Effect of the Chamomile Plants as a
Medicinal Plant
737 Systematic Review Pharmacy Vol 11, Issue 6, 2020
Cadmium element
Is measured cadmium concentration in the plant
chamomile, as shown in Figure (9). Where it was observed
that the highest percentage of the concentration of the
element in the chamomile plant when the temperature (70 °
C (
Figure 9: Which shows the concentration of cadmium (Cd) in the plant chamomile varying degrees heat
As for the impact of changing times on the concentration of cadmium in the plant was the highest concentration of him after
(40 minutes), as illustrated in Figures (10).
Figure 10: Which shows the concentration of cadmium (Cd) in the plant chamomile change time
Compared to the concentration of elements in the
chamomile plant after 24 hours
The comparison between the concentrations of various
elements in the chamomile plant after 24 hours of plant Add
to distilled water at normal conditions of temperature.
Without external influences, as illustrated in Figure (11) as
it shows that the highest percentage of the concentration of
elements was the zinc concentration in the following order.
0
0.2
0.4
0.6
0.8
1
1.2
1.4
1.6
0 5 10 15 20 25 30 35 40 45 50 55 60 65 70 75 80 85 90 95100105
(Cd) (Con.ppm)
Tem.
Measuring the concentration of cadmium in the
chamomile plant
0
0.1
0.2
0.3
0.4
0.5
0.6
010 20 30 40 50 60
(Cd) (Con.ppm)
Time
Measuring the concentration of cadmium in the
chamomile plant
Suaad Abd Al Mahdi Abd Noor / Studying the Pharmaceutical; Elements and Bio-Effect of the Chamomile Plants as a
Medicinal Plant
738 Systematic Review Pharmacy Vol 11, Issue 6, 2020
Figure 11: Illustrates the comparison between the concentration of elements in the chamomile plant
Zn > Cd > Fe >Pb> Cu
From the results that have been reached to plant drugs is
still used natural condition As a folk medicine known as
pharmacists, doctors and patients had come to view
medicinal plants as an important source of these beneficial
substances in many countries of the world (the United
States - China - India) no independent institutes and huge
institutions of hundreds of specialists scientists to confine
this botanical wealth and benefit from the availability of
medication local materials. One of these medicinal plants
(licorice, chamomile, fenugreek) and known herbal
medicine or herbal medicine as a study of the use of the
medicinal properties of the plant (Lack, Caleb W.et al.
2016).
The importance of chamomile plant lies in addition to
volatile oil Blue caused material Alkmasulan counter
(Chamomile), which deals with skin infections and tonic to
the hair follicle. Included in many of the cosmetics and hair
acquires beautiful colors. As well as there is a great benefit to
the steam Chamomile flower is used gargling for tonsillitis
and mouth ulcers (Weston A. Price; 2007, Kyokong O; et.
al,2002, Diane L. McKay; et. al,2006).It is used to treat all
pain cramping such as intestinal colic and kidney and
urinary burning and inflammation of the bladder and uterus
colic (Aronson, Jeffrey K. 2008 , Diana Wells2018).And also
falls within the painkillers from intestinal colic and
stimulates digestion and is also used to get rid of
constipation (Weston A. Price; 2007).
Through the results obtained from the current study that
contain plant chamomile on some metal elements as they
have a great interest in the effectiveness of the plant
chamomile and therapeutic effectiveness in biological
processes within the human body as an iron (Fe) big
importance for being concentrated by (60%) of it in the
blood (red blood cells) in the liver, spleen, kidneys, bone
marrow and muscle. as well as entering in the composition
of the enzymes responsible for the oxidation of
carbohydrates and fatty proteins and enters in the
composition Maoklopan muscle (Myoglobin) responsible
for storing oxygen to be used in muscle contraction and the
iron absorption in the upper part of the small intestine in
the form of ferrous compounds with the help of gastric
juices and vitamin c, which in turn strengthens the immune
system and increase the body's ability to resist disease. To
absorb iron must be a sufficient amount of hydrochloric
acid in the stomach so that the absorption of iron is needed
also to the presence of copper element and vitamin A and
vitamin B complex to ensure Full absorption of iron and on
the other hand, excessive amounts of zinc and vitamin E
impede the absorption of iron. And when there is a lack of
iron, there will be dry skin and pale and digestive disorders,
drowsiness, fatigue and shortness of breath fast and
palpitations of the heart and other diseases as a result of a
deficiency in the human body, and when increasing the
proportion of iron in the body excessively also lead to
medical conditions but the danger at least shrink the
existence of an increase in the levels of zinc (Fabricant DS,
et.al, 2001, Nanami N.; et al. 2005). In addition to that
there are several benefits to your weight where interactions
involved in anti-oxidants and keeps the senses of smell and
taste, as well as playing an important role in the carbon
dioxide in the blood transfusion.
As well as his role in the secretion of gastric acid and helps
regulate blood pressure and promotes natural growth, as
well as the growth of the fetus (Nanami N.; et al. 2005 ).
As for copper (Cu) and the job he enters in the composition
of many enzymes so inevitable (Stern, Bonnie Ransom ;et.al
2007). To maintain the heart, bones, nerves, and brain and
red blood cells healthy. It is also important for proper
absorption of iron and if the body does not get the required
amount of copper, the production of hemoglobin (red blood
hemoglobin) is decreasing and the result is a type of anemia
(caused by copper deficiency), as well as a copper deficiency,
can weaken the ability of white blood cells to fight infection.
Copper is working with the balance of zinc and vitamin C to
form (elastin) Yellow flexible element found in tissues
(Cordano, A 1978, Jump up to:a b Danks, D M 1988, Klevay,
LM 1980,Strain, J. J. 1994).Result in an increase or decrease
0
2
4
6
8
10
Fe Cu Zn Cd Pb
0.2959 0.1451
9.1881
0.4854 0.2171
The concentration of elements in the chamomile
plant temper with water for 24 hours
Suaad Abd Al Mahdi Abd Noor / Studying the Pharmaceutical; Elements and Bio-Effect of the Chamomile Plants as a
Medicinal Plant
739 Systematic Review Pharmacy Vol 11, Issue 6, 2020
key micronutrients (Fe, Zn, Cu) of the undesirable effects
(Masud ,K.and M., Jaffar 1997). While the cause of toxic
elements of the two elements (Cd, Pb) to the occurrence of
many problems as it leads to the occurrence of cadmium
(Pyelonephritis, Oesteomolica) and matched by bullets that
cause cancerous tumors and kidney (Shumacher M.;M. A.et.
al,1991). The element of lead is known as an extremely
harmful to humans, plants, and is the confiscation of the
plants to use some organic fertilizers highest concentration
allowed in food is (1 mg/kg).The resulting long-term
exposure to lead to an increase of lead in the body and many
serious symptoms such as anemia and pallor of the skin and
abdominal pain, nausea, vomiting and paralysis in the joints
fertility and reduce or increase the chance of a pregnancy
failure or the occurrence of birth defects (Grath S.P .Mc .and
S. ,Smith1990).As for cadmium, it is toxic element has no
function in the plant or animal or human, and when its
accumulation in the college remains by causing high blood
pressure and kidney disease and are difficult to remove
directing and lead cadmium direct damage to nerve cells
because it prevents the formation of ethyl Colin and
activates the enzyme choline esterase (Colin esterase ) and
the reduction of embarrassment for cadmium (3-5 mg/kg)
(Pendias, A.K. and H.,Pendias 1984). It is necessary to plant
the content of these elements to measure it has been allowed
for these elements in plants border situation (Cd = 0.5, Cu =
20, Fe = 50, Zn = 100, Pb = 0.1) (Haider S.;V.Naithani; et.al,
2004).
Among the results obtained in this study weights of the elements studied account by following the formula below:
Wt. (x)
1 106 ـــــــــــــــــــــــــــــــــــــ ×(x) ppm =
V liter
V liter × (x) ppm
.. (2 ـــــــــــــــــــــــــــــــــــــ(x) Wt. =
106
Table 1: The application of this equation was obtained at the highest weights of these elements in the chamomile plant
Element
Standard weight and
allowable(Micrograms / gram
dry weight)
The measured weight of the
component
Fe
50
0.05918
Cu
20
0.02902
Zn
100
1.8376
Cd
0.5
0.097
Pb
1 (mg/g)
0.04342
Table 2: The nutritional value of boiled chamomile (www.fdc.nal.usda.gov, Retrieved 2019).
The nutritional component
Quantity
water
99.7 ml
Calories
1 cal
Carbohydrates
0.2 gm
Calcium
2 Milligrams
Iron
0.08 Milligrams
magnesium
1 Milligrams
Potassium
9 Milligrams
Sodium
1 Milligrams
Zinc
0.04 Milligrams
Copper
0.015 Milligrams
Manganese
0.044 Milligrams
Vitamin B1
0.01 Milligrams
Vitamin B2
0.004 Milligrams
Vitamin B5
0.011 Milligrams
Folate
1 mgr
Vitamin A
20 unit
Suaad Abd Al Mahdi Abd Noor / Studying the Pharmaceutical; Elements and Bio-Effect of the Chamomile Plants as a
Medicinal Plant
740 Systematic Review Pharmacy Vol 11, Issue 6, 2020
RECOMMENDATIONS AND CONCLUSIONS
1. You must measure the proportion of heavy elements of
plants and herbal medical knowledge concentration ratios to
judge the usefulness or disadvantages compared with the
permissible ratios.
2. follow modern scientific methods of oil extraction and
processing materials in herbal medicinal plants to be used as
an alternative medicine and move away from the use of
traditional methods.
3. Do not use medicinal plants as alternative medicine in
case of lack of experience in this area and the lack of
knowledge and expertise of chemical and natural
ingredients.
4. The acquisition of medicinal plants of the few areas of
environmental and industrial pollution on either end so as
to move away from high concentrations of the elements in
the plant and that it is concentrated as a result of pollution
in all its forms.
5-Non-use of organic fertilizers without knowing because
they contain concentrations of elements that may increase
the concentration in the herbal plant which are causing
many diseases.
REFERENCES
1. Sarris, J; Panossian, A; Schweitzer, I; Stough, C;
Scholey, A (December 2011). "Herbal medicine for
depression, anxiety, and insomnia: a review of
psychopharmacology and clinical evidence". European
Neuropsychopharmacology. 21 (12): 841 860.
2. Saller R, Beschomer M, Hellenbrecht D, et al. Dose
dependency of symptomatic relief of complaints by
chamomile steam inhalation in patients with common
cold. Eur J Pharmacol 1990;183:728-729.
3. Janmejai K Srivastava, Eswar Shankar, and Sanjay
Gupta (2011), "Chamomile: A herbal medicine of the
past with bright future", Mol Med Report, Issue 3,
Folder 6, Page 895-901.
4. Ahmed Gohar, Ahmed Zaki (2014), "Assessment of
some Herbal Drugs for Prophylaxis of Peptic Ulcer",
Iranian Journal of Pharmaceutical Research, Issue 3,
Folder 13, Page 1081 1086.
5. Ross SM. Chamomile: a spoonful of medicine. Holistic
Nursing Practice. 2008;22:56 57.
6. Elena Riza, Athena Linos, Athanassios Petralias, and
others (2015), "The effect of Greek herbal tea
consumption on thyroid cancer: a case-control study
", European Journal of Public Health, Issue 6, Folder
25, Page 1001 1005.
7. Shumacher M.;M. A. Bosque and
J.L.Doming,J.Carbella(1991)Bull
environ.toxicol,46,320.
8. Rafraf M, Zemestani M, Asghari-Jafarabadi M (2015),
"Effectiveness of chamomile tea on glycemic control
and serum lipid profile in patients with type 2
diabetes", Journal of Endocrinological Investigation,
Issue 2, Folder 8, Page 163 170.
9. Saira Khan, Rahila Najam, Humera Anser, and others
(2014), "Chamomile tea: herbal hypoglycemic
alternative for conventional medicine.", Pakistan
Journal of Pharmaceutical Sciences, Issue 5, Folder 27,
Page 1509-1514.
10. Lack, Caleb W.; Rousseau, Jacques (2016). Critical
Thinking, Science, and Pseudoscience: Why We Can't
Trust Our Brains. Springer Publishing Company.
pp. 212 214.
11. Wise Traditions in Food, Farming and the Healing
Arts, the quarterly magazine of the Weston A. Price
Foundation, spring 2007.
12. Kyokong O, Charuluxananan S, Muangmingsuk V, et
al. Efficacy of chamomile-extract spray for prevention
of post-operative sore throat. J Med Assoc Thai
2002;85 Suppl 1:S180-S185.
13. Diane L. McKay, Jeffrey B. Blumberg (2006), "A
review of the bioactivity and potential health benefits
of chamomile tea (Matricaria recutita L.).",
PHYTOTHERAPY RESEARCH, Issue 7, Folder 20,
Page 519 530.
14. Aronson, Jeffrey K. (2008).Meyler's side Effects of
Herbal medicines .Elsevier .ISBN 9780080932903.
15. Diana Wells (6-11-2018), "Chamomile Tea While
Pregnant: Is It Safe?" ،www.healthline.com, Retrieved
2-2-2020.
16. Fabricant DS, Farnsworth NR(march 2001).,,the value
of plants used in traditional medicine for drug
discovery,, .Environ. Health prospect.109 suppl
1(suppl 1):69 -75 .pmc 1240543.PMID 11250806.
17. Nanami N. ; et al. (2 005). "Tumor necrosis
factor- -induced iron sequestration and
oxidative stress in human endothelial
cells". Arterio sclerosis, thrombos is, and
vascular biology. 25 (12): 2495
2501. doi:10.1161/01.ATV.0000190610.63878.2
0.
18. Stern, Bonnie Ransom; Solioz, Marc; Krewski, Daniel;
Aggett, Peter; Aw, Tar-Ching; Baker, Scott; Crump,
Kenny; Dourson, Michael; Haber, Lynne; Hertzberg,
Rick; Keen, Carl; Meek, Bette; Rudenko, Larisa;
Schoeny, Rita; Slob, Wout; Starr, Tom (2007). "Copper
and Human Health: Biochemistry, Genetics, and
Strategies for Modeling Dose-response
Relationships". Journal of Toxicology and
Environmental Health, Part B. 10 (3): 157 222.
19. Cordano, A (1978). "Copper deficiency in clinical
medicine". In Hambidge, K. M.; Nichols, B. L.
(eds.). Zinc and Copper in Clinical Medicine. New
York: SP Med. Sci. Books. pp. 119 26.
20. Jump up to:a b Danks, D M (1988). "Copper Deficiency
in Humans". Annual Review of Nutrition. 8: 235 57.
21. Klevay, LM (1980). "The influence of copper and zinc
on the occurrence of ischemic heart disease". Journal
of Environmental Pathology and Toxicology. 4 (2 3):
281 7.
22. Strain, J. J. (1994). "Newer aspects of micronutrients in
chronic disease: copper". Proceedings of the Nutrition
Society. 53 (3): 583 98.
23. Masud ,K.and M., Jaffar
(1997)J.Chem.Soc.pak.,19(1),49.
Suaad Abd Al Mahdi Abd Noor / Studying the Pharmaceutical; Elements and Bio-Effect of the Chamomile Plants as a
Medicinal Plant
741 Systematic Review Pharmacy Vol 11, Issue 6, 2020
24. Shumacher M.;M. A. Bosque and
J.L.Doming,J.Carbella(1991)Bull
environ.toxicol,46,320.
25. Grath S.P .Mc .and S. ,Smith(1990) ,,Chromium and
nickel in heavy metals in soils,,, Ed. B. J.
Aloway,blackie,Glasgow,125 .
26. Pendias, A.K. and H.,Pendias (1984),,Trace elements
in soils and plants,, 2nd ed. Boca raton.fi. CRC press.
27. Haider S.;V.Naithani;J. Berthwal and P. Kakkas(2004)
.heavy metal content in some therapeutically
important medical plants, bull. of environ.
contamination and technology,1:119-127.
28. "Beverages, tea, herb, brewed, chamomile",
www.fdc.nal.usda.gov, Retrieved 26-12-2019.
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