The male factor is the cause of infertility in 40 % of cases. This study is dedicated to the efficiency assessment of ICSI and PICSI techniques and the determination of indications of these methods. There are some relative indications for ICSI in clinical practice: advanced reproductive age of patients, a small number of obtained oocytes, prolonged infertility, repeated attempts of in vitro
... [Show full abstract] fertilization. However, normal sperm values are registered in 71.3 % of cases. PICSI method is more preferable at high level of DNA fragmentation and associated changes in sperm indicators. Nevertheless, the pregnancy rate after these methods was comparable – 19.3 % and 19.7 % respectively. The results indicate that the ICSI and PICSI methods do not have a negative impact on the quality of the embryos and do not increase the pregnancy rate.
