ChapterPDF Available


Cucumber is a healthy fruit which having lots of benefits. Cucumber regulates hydration and maintain adequate blood pressure and sugar, soothes skin, helped in digestion and reduces fat and help to weight loss. Cucumber contains a plenty of potassium, fiber, magnesium, manganese and vitamin A, C, K. Cucumber has several health beneficial activities such as antimicrobial properties, hydrating and detoxification, help in digestion and weight loss, preventing cancer and other fragile bone disease. In this book chapter we have discussed about the health beneficial activities of cucumber along with its different contents.
Selection of our books indexed in the Book Citation Index
in Web of Science™ Core Collection (BKCI)
Interested in publishing with us?
Numbers displayed above are based on latest data collected.
For more information visit
Open access books available
Countries delivered to Contributors from top 500 universities
International authors and editor s
Our authors are among the
most cited scientists
We are IntechOpen,
the world’s leading publisher of
Open Access books
Built by scientists, for scientists
TOP 1%
Health Beneficial Effects of
ShampaChakraborty and SadhanaRayalu
Cucumber is a healthy fruit which having lots of benefits. Cucumber regulates
hydration and maintain adequate blood pressure and sugar, soothes skin, helped
in digestion and reduces fat and help to weight loss. Cucumber contains a plenty
of potassium, fiber, magnesium, manganese and vitamin A, C, K. Cucumber has
several health beneficial activities such as antimicrobial properties, hydrating and
detoxification, help in digestion and weight loss, preventing cancer and other frag-
ile bone disease. In this book chapter we have discussed about the health beneficial
activities of cucumber along with its different contents.
Keywords: cucumber, health impact
1. Introduction
Cucumbers (scientifically known as Cucumis sativus) belong to the same botani-
cal family as melons and squashes. Cucumbers are served into two types. “Slicing
cucumbers” for fresh consumption and “Pickling cucumbers” for eventual process-
ing into pickles. Slicing cucumbers are usually larger with skins, while pickling
cucumbers are smaller having thinner skins. Cucumbers are very low in calories but
contain important vitamins, minerals and high water content. Eating cucumbers
may lead to many potential health benefits, including weight loss, balanced hydra-
tion, digestive regularity and lower blood sugar levels. The present chapter deals
with the different health beneficial effects of cucumber fruit as well as its contents.
Fresh cucumbers are one of the fantastic fruit. Eating habits of cucumber are great
as we are accustomed to eat cucumber with their seeds. This habit has an outstand-
ing health benefits. Cucumber seeds contain a wide variety of phytonutrients,
including both carotenoids and flavonoids.
2. Result and discussions
2.1 Antimicrobial activity
Khan et al. [1] reported that Cucumber have poor activity against Pseudomonas
aeruginosaonly. Osuagwu et al. [2] reported that ethanolic extracts of leaf have
antimicrobial property on pathogenic microorganisms for three human pathogens
S. aureus, P. aeruginosa and S. typhi except E. coli pathogens. Sood et al. [3] reported
antimicrobial activity of seeds of Cucumber family- members Karella, Cucumber,
Tinda, Kaddu, loki. All seeds extracts are effective against Serratiamarcescens,
Studies on Cucumber (Cucumis sativus L.)
E. coli, Streptococcus thermophilous, and showed no inhibition against Asper-
gillusniger, Candida albicans. Mallik et al. [4] reported antifungal potentials of the
ethanol extract of Cucumber against six fungus. The diameter of zone of inhibition
have similar activity of the standard drug, Griseofulvin.
2.2 Phytochemical analysis
Sood et al. [5, 6] confirmed the presence of various phytochemicals like tannins,
cardiac glycosides, terpenoides, carbohydrates, resins, saponins and phytosterols.
Phytochemical screening by color visualization in cucumber showed the presence
of flavonoid, tannin, saponin and steroid. The spectrophotometric analysis showed
flavonoid 0.36% (w/w), phenol 0.40% (w/w), and, the by titrimetry found tan-
nin 2.82%.
2.3 Nutritional composition
Urooj et al. [7] reported that among all varieties, English, Zucchini and Pranic
healed cucumbers have contained highest moisture and lowest in Holenarasipur and
Dotted variety. Eghtedary et al. [8] reported twenty types of cucumber (Cucumis
sativus) from different regions. Khan [9] reported 24 genotypes of cucumber based
on Randomized Complete Block Design (RBCD) method.
Cucumber, sliced, raw 1.00 cup (104.00 grams) calorie-16.
3. Different types of nutrients in cucumber
Cucumber contains different types of flavonoids such as apigenin, diosmetin,
fisetin, luleolin, quercetin, kaempferol, luteolin, naringenin, theaflavanoside
I, vicenin. It also contains different types lignans pinoresinol, lariciresinol and
secoisolariciresinol and triterpenes like cucurbitacin A, cucurbitacin B, cucurbita-
cin C, cucurbitacin D.
3.1 Medicinal uses
Shrivastava et al. [10] reported that cucumber eating in daily basis can improve
hair growth and soothes skin, reduce swelling of eye. Cucumber juice can improve
the skin texture and cures skin infections, eczema. A piece of cucumber on the
Vitamin K 19%
Molybdenum 12%
Pantothenic acid 5%
Copper 4%
Phosphorus 4%
Vitamin C 4%
Biotin 3%
Vitamin B1 3%
Potassium 3%
Magnesium 3%
Manganese 3%
Health Beneficial Effects of Cucumber
head for a sun stroke patient can reduce the heat of the body. Cucumber can help
in weight loss and the mashed seeds with sugar before meal can reduce intestinal
worms and tape worms. Boiled cucumber leaves and cumin seed roasted pow-
ders can be used for throat infections. Kashif et al. [11] reported that cucumber
contained high potassium so it can help to keep normal blood pressure.
3.2 Different health beneficial activities of cucumber
Sharma et al. [12] proved that cucumber juice can acts against acidity and resist
to change in pH and have good carminative and antacid potential. Cucumber
has also eye soothner activities. Keeping cucumber slices on the eyes for about
10minutes relaxes our eyes and reduces puffiness around the eyes. Patil et al. [13]
investigated activity of cucumber extract in laboratory animals. They proved that
the aqueous extract of cucumber selected can reduce the induced bowel disease and
possessed active against ulcerative colitis. Patil et al. [14] investigated that cucum-
ber juice can have significant wound healing effect.
3.3 Hepatoprotective activity
Heidari et al. [15] investigated the activity of cucumber juice against cumene
hydroperoxide induced-oxidative stress and proved that cucumber can acts as
antioxidant agent. The cucumber extracts have antioxidants and radical scavenging
property. The extract help to form intracellular ROS.
3.4 Hypoglycemic and hypolipidemic activity
Sharmin et al. [16] investigated Hypoglycemic effects of cucumber and proved
white pumpkin, gourd has anti hyperglycemic effects on Alloxan Induced Diabetic
Rats (AIDR). The extract can lessen the high lipid profiles in AIDRs. Therefore,
cucumber extracts can be useful, in the therapy of diabetes, hyperglycemia and
3.5 Hydration & detoxification
Cucumbers contains 96% water. Therefore, it helps to fill up the daily require-
ment of water by the body and keep body hydrated. In summers, people tend
to dehydrate easily. Consuming cucumber can make hydrate and it also acts as a
coolant and give relief from the summer heat. Cucumber and mint can use to make
detox water which effectively eliminates toxins from the body, improves hydration
and thus results in innumerable health benefits.
3.6 Reduce blood pressure
Cucumbers are a good source of potassium, magnesium and dietary fibre.
These nutrients are known to lower blood pressure, thus reducing the risk of heart
diseases. Research has also proved that regular consumption of cucumber juice was
helpful in reducing blood pressure, in elderly people with hypertension.
3.7 Digestion
Cucumbers act as a coolant for our stomach. The soluble fibre in cucumbers
helps in slowing our digestion. Also, the high content of water in cucumber makes
our stools soft, prevents constipation and keeps our bowel movements regular.
Studies on Cucumber (Cucumis sativus L.)
3.8 Reduces blood sugar
Cucumbers are known to reduce blood sugar levels, thus being helpful in the
management and prevention of diabetes mellitus.
3.9 Weight loss
Cucumbers contain 96% of water and are low in calories. There are only 15.5
calories in 100g of cucumber. High water and low-calorie content of cucumbers,
helps in reducing weight.
3.10 Skin
Cucumbers can enhance beauty and have good effects on the skin. Application
of cucumber juice on skin makes it soft and glowing. Anti-inflammatory effects of
cucumber naturally lighten our skin and reduce tanning. It also reduces wrinkles
and fine lines.
3.11 Reduces risk of cancer
The fibre in cucumbers protects from colorectal cancer. Also, cucurbitacin
present in cucumbers possesses anti-cancer properties. Tuama et al. [17] showed
cucumber extract is rich in bioactive compounds and have anticancer activity with
Cell lines of (IC50) with MCF 715.6±1.3 and HeLa 28.2±1.
4. Effect in hair, nails and breath
Cucumbers contain silica which is excellent for hair and nail care. They help
in strengthening the nails and prevent them from becoming brittle. Moreover,
phytochemicals present in cucumber destroy the bacteria in our mouth that cause
bad breath.
4.1 Antioxidant activity
Kumaraswamy [18] demonstrated that the yellow cucumber posses more anti-
oxidant activity where as While green and white cucumbers have low antioxidant
property. The antioxidant activity is due to the carotenoids, phenolic flavonoids,
tannins, polyphenols and lycopene, found in it. Mallik et al. [19] carried out an
study on the cytotoxic activity of cucumber extract in ethanol.
Cucumber, sliced, raw 1.00 cup (104.00 grams) calorie-16
Nutrient Amount DRI/ DV (%)
Protein 0.68g 1
Carbohydrate 3.78g 2
F a t -To t a l 0.11g 0
Dietary Fibers 0.52g 2
Calories 15.60 1
Total sugar 1.74g
Monosaccharides 1.70g
Health Beneficial Effects of Cucumber
Cucumber, sliced, raw 1.00 cup (104.00 grams) calorie-16
Nutrient Amount DRI/ DV (%)
Fructose 0.90g
Glucose 0.79g
Galactose 0.00g
Disaccharides 0.04g
Lactose 0.00g
Maltose 0.01g
Sucrose 0.03g
Soluble Fiber 0.06g
Insoluble Fiber 0.46g
Other carbohydrate 1.52g
Monosaturated fat 0.01g
Polysaturated fat 0.03g
Saturated fat 0.04g
Trans fat 0.00g
Calories from fat 1.03
Insoluble fiber 0.46g
Other carbohydrate 1.52g
Calories from saturated fat 0.35
Calories from trans fat 0.00
Cholesterol 0.00
Wat er 99.04g
Vitamins (water soluble)
Vitamin B1 0.03mg 3
Vitamin B2 0.03mg 2
Vitamin B3 0.10mg 1
Vitamin B3 (Niacin equivalent) 0.19mg
Vitamin B6 0.04mg 2
Vitamin B12 0.00 mcg 0
Biotin 0.94 mcg 3
Choline 6.24mg 1
Folate 7.28 mcg 2
Folate DFE 7.28 mcg
Folate food 7.28 mcg
Pantothenic acid 0.27mg 5
Vitamin C 2.91mg 4
Fat soluble vitamins
Vitamin A international unit 109.20IU
Vitamin D 0.00IU 0
Vitamin K 17.06 mcg 19
Studies on Cucumber (Cucumis sativus L.)
5. Conclusion
Cucumber is an excellent and unusual food. A cup of cucumber contained 16
calorie with its peel (15 without) and 4 percent of your daily potassium, 3 percent
of your daily fiber and 4 percent of your daily vitamin C. Cucumbers also contained
small amounts of vitamin K, vitamin C, magnesium, potassium, manganese and
vitamin A among them Vitamin K is very important for bone health. Vitamin K
intake reduces fracture rates, and combine work with vitamin D can increase bone
density and positively affect calcium balance. Vitamin K helps in building bones
and the effects seem to be important for women. Low vitamin K levels were associ-
ated with low bone density in women, but not in men. Low intakes of vitamin K
were associated with an increased risk of hip fractures in middle-age women.
Authors thank the SERB (PDF/2016/002856) (Govt. of India) for financial
support and Knowledge Resource Center-NEERI for checking plagiarism. (KRC
No.:CSIR-NEERI/KRC/2021/Jan/EMD/1). SC acknowledges Director-NEERI for his
overall support.
Cucumber, sliced, raw 1.00 cup (104.00 grams) calorie-16
Nutrient Amount DRI/ DV (%)
Vitamin E 0.05IU
Boron 0.00mg
Calcium 16.64mg 2
Chloride 0.00
Chromium 0.00
Copper 0.04 4
Fluoride 0.00 0
Iodine 0.00mg
Iron 0.29mg 2
Magnesium 13.52mg 3
Manganese 0.08mg 3
Molybdenum 5.20 mcg 12
Phosphorus 24.96mg 4
Potassium 152.88mg 3
selenium 0.31 mcg 1
Sodium 2.08mg 0
Zinc 0.21mg 2
The nutrient profiles provided in this chapter are derived from The Food Processor, Version .., ESHA Research,
Salem, Oregon, USA.
Health Beneficial Effects of Cucumber
Author details
ShampaChakraborty* and SadhanaRayalu
Environmental Materials Division, National Environmental Engineering Research
Institute, Nagpur, India
*Address all correspondence to:
© 2021 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms
of the Creative Commons Attribution License (
by/3.0), which permits unrestricted use, distribution, and reproduction in any medium,
provided the original work is properly cited.
Studies on Cucumber (Cucumis sativus L.)
[1] D. A. Khan, F. Hassan, H. Ullah, S.
Karim, A. Baseer, M. A. Abid, M. Ubaid,
S. A. Khan and G. Murtaza. Anti-
bacterial Activity OfPhyllantusEmblica,
CoriandrumSativum, Culinaris Medic,
Lawsonia Alba And CucumisSativus.
ActaPoloniaePharmaceutica n Drug
Research, 70(5): 855-859, 2013.
[2] G. G. E. Osuagwu and F. O. Ejikeme.
The Antimicrobial Activity of the
Leaves of Some Wild Cucurbitaceae
Species from South-East Nigeria.
Human JournalsResearch ArticleMarch
2(4): 2015.
[3] A.Sood, P. Kaur and R. Gupta.
Phytochemical Screening And
Antimicrobial Assay Of Various Seeds
Extract Of CucurbitaceaeFamily.
International Journal of Applied Biology
and Pharmaceutical Technology, 3(3):
401-409, 2012.
[4] J.Mallik., R.Akhter. Phytochemical
Screening and In-vitro Evaluation of
Reducing Power, Cytotoxicity and Anti-
Fungal Activities of Ethanol Extracts
of Cucumissativus. International
Journal of Pharmaceutical & Biological
Archives,3(3): 555-560, 2012.
[5] A.Sood, P. Kaur and R. Gupta.
Phytochemical Screening And Anti-
microbial Assay Of Various Seeds
Extract Of CucurbitaceaeFamily.
International Journal of Applied Biology
and Pharmaceutical Technology, 3(3):
401-409, 2012
[6] Jet S. Mandey, Fenny R. Wolayan,
Cherly J. Pontoh, and Bonie F. J.
Sondakh, Journal of Advanced
Agricultural Technologies, Vol.
6, 1, 2019
[7] T. Keerthika, C. S. Devaki, F. Suma
and A. Urooj. Studies on the Nutritional
and Quality Characteristics of
CucumisSativusVarieties .Agricultural
Science Research Journal Vol. 6(4):
79-85, 2016.
[8] M. Golabadi, P. Golkar and
A.R Eghtedary. Assessment of
genetic variation in cucumber
(CucumissativusL.) genotypes.
European Journal of Experimental
Biology, 2 (5):1382-1388, 2012.
[9] Z. Khan, A. H. Shah, R. Gul, A.
Majid, U. Khan, H. Ahmad. Morpho-
agronomic characterization of
cucumber germplasm for yield and yield
associated traits.InternationalJournal of
Agronomy and Agricultural Research
(IJAAR)ISSN: 2223-7054 (Print) 2225-
3610 (Online) 6(1), 1-6, 2015.
[10] Dr. A. Shrivastava, Dr.S. Roy.
Cucurbitaceae: AEthnomedicinally
Important Vegetable Family.Journal of
Medicinal Plants Studies., 1(4):16-20,
ISSN: 2320-3862, 2013.
[11] W.Kashif, Q. M. Kamran, M. S.
Jilani. Effect of Different Nitrogen
Levels on Growth and Yield of
Cucumber (Cucumissativus L.). J.
Agric. Res. 46(3): 259-266, 2008.
[12] S. Sharma., J.Dwivedi., S.Paliwal.
Evaluation of antacid and carminative
properties of Cucumissativus under
simulated conditions. Scholars Research
Library Der Pharmacia Lettre, 4(1):
234-239, 2012.
[13] K.Patil., A Kandhare., D
Bhise. Effect of aqueous extract
of Cucumissativus Linn. fruit in
ulcerative colitis in laboratory animals.
Asian Pacific Journal of Tropical
Biomedicine:962-969, 2012.
[14] K.Patil., A.Kandhare., D.Bhise.
Pharmacological evaluation of
ameliorative effect of aqueous extracts
of CucumissativusL.fruit formation on
wound healing in Wister rats.Chronicles
of young scientists. 2(4),207-213, 2012.
[15] H.Heidari, M.Kamalinejad,
Health Beneficial Effects of Cucumber
activity of Cucumissativus against
cumenehydroperoxide induced-
oxidative stress. Research in
Pharmaceutical Sciences,; 7(5): 936-
939, 2012.
[16] R.Sharmin., M. Khan., M.Akhter.,
A.Alim., A. Islam., and M. Ahmed.
Hypoglycemic and Hypolipidemic
Effects of Cucumber, White Pumpkin
and Ridge Gourd in Alloxan Induced
Diabetic Rats. J. Sci. Res. 5 (1), 161-170.
[17] A. A. Tuama, A. A. Mohammed,
Saudi Journal of Biological Sciences, 26,
600-604, 2019
[18] L. Kumaraswamy. A comparative
study on antioxidant activities of three
cultivars of Cucumissativas (Linn).
International Journal of Research in
Biotechnology and Biochemistry,2016.
[19] J. Mallik., R. Akhter. Phytochemical
Screening and In-vitro Evaluation of
Reducing Power, Cytotoxicity and Anti-
Fungal Activities of Ethanol Extracts
of Cucumissativus. International
Journal of Pharmaceutical & Biological
Archives; 3(3): 555-560, 2012.
... The soluble fibre in cucumbers helps in slowing our digestion. Also the high content of water in cucumber makes our stools soft, prevents constipation and keeps our bowel movements regular (Chakraborty and Rayalu, 2021). ...
... The juice of cucumber when apply on skin makes it soft and glowing. Cucumber regulates hydration and maintains blood pressure and sugar, soothes skin, helped in digestion, reduces fat and help to weight loss (Chakraborty and Rayalu, 2021). ...
Full-text available
Cucumber is a one of healthy fruit which have many health benefits of cucurbitaceae family. It maintains blood pressure, regulates hydration, controls sugar, and soothes the skin, helpful in digestion. It also helps to weight loss by reducing fat. Cucumber also contains fibre, potassium, manganese, magnesium and vitamin K, C, A. Cucumber can also have hydrated and antimicrobial properties, and detoxify the body and, prevent cancer and other many bone disease. Economically cucumbers are very important, as cucumbers contain high nutritional, medicinal as well as health beneficial values. In present presentation going to discussed about the economic importance of cucumber (Cucumis sativus). Int. J. Appl. Sci. Biotechnol. Vol 10(1): 12-15.
... In Poland, cucumber production under covers (in greenhouses and plastic tunnels) is carried out in an area of over 1000 hectares and results in harvesting about 300,000 tonnes of fruits per year [2,3]. Cucumber fruits are a low-calorie, alkaline component of the human diet, containing numerous minerals (including potassium, calcium and magnesium), vitamins (e.g., K, C, folate), carotenoids, flavonoids and triterpenes [4,5]. plant active substances, carotenoids belong to the groups of special interest as vitamin A precursors, antioxidants and potential anti-cancer agents [26]. ...
Full-text available
Supplemental lighting with light-emitting diode (LED) lamps and/or high-pressure sodium (HPS) lamps was applied to increase the activity of the photosynthetic apparatus and thus productivity of greenhouse cucumber (Cucumis sativus L.) in a high-wire growing system. The colocalisation of the chlorophyll of PSII (located mainly in grana) and carotenoid fluorescence signals in chloroplasts of cucumber leaves was studied under confocal microscopy. Leaf anatomy and some chemical quality traits (dry matter, chlorophyll, carotenoids, total soluble solids, total sugars and nitrate reductase activity) as well as selected chlorophyll fluorescence parameters were also investigated and subjected to the multidimensional principal component analysis together with the data on fruit yield. Under LED lighting, a lower correlation between the occurrence of chlorophyll and carotenoid fluorescence signals was observed, especially in older (lower-located) leaves, which may have resulted from changes in the distribution of carotenoids within chloroplasts and/or relative concentrations of chlorophyll and carotenoids. Compared to toplighting with HPS lamps, most commonly used in commercial greenhouse cucumber production, the application of LED interlighting, especially in combination with LED toplighting, led to the increase in chlorophyll and carotenoid content and photosynthetic performance index in older leaves, which was related to the increased cucumber productivity.
... Cucumber is one of the main protected culture crops grown in the Mediterranean region because it has potential health benefits and is quite well adapted to grow under different protected culture conditions [1][2][3]. Furthermore, the greenhouse industry has rapidly expanded worldwide, together with demanding new strategies to solve specific biotic and abiotic stress-limiting production factors [4][5][6][7]. Water stress is one of the most important factors restricting the development of agricultural extension in countries and regions with scarce water resources. ...
Full-text available
Water stress is the most critical aspect restricting the development of agriculture in regions with scarce water resources, which requires enhancing irrigation water-saving strategies. The current work discusses the potential application of the plant-strengthening root endophyte Piriformospora indica against moderate (25% less irrigation water) and severe (50% less irrigation water) water stress in comparison to the optimum irrigation conditions of greenhouse cucumbers. P. indica improved growth, nutrient content, and photosynthesis apparatus under normal or water-stress conditions. On the other hand, moderate and severe water stress reduced yield up to 47% and 83%, respectively, in non-colonized cucumber plants, while up to 28 and 78%, respectively, in P. indica-colonized plants. In terms of water-use efficiency (WUE), P. indica improved the WUE of colonized cucumber plants grown under moderate (26 L/kg) or severe stress (73 L/kg) by supporting colonized plants in producing higher yield per unit volume of water consumed by the crop in comparison to non-colonized plants under the same level of moderate (43 L/kg) or severe (81 L/kg) water stress. Furthermore, P. indica increased the indole-3-acetic acid (IAA) content, activity levels of catalase (CAT) and peroxidase (POD) with an apparent clear reduction in the abscisic acid (ABA), ethylene, malondialdehyde (MDA), proline contents and stomatal closure compared to non-stressed plants under both water-stress levels. In addition, chlorophyll a, b, a + b contents were increased in the leaves of the colonized plants under water-stress conditions. This improvement in chlorophyll content could be correlated with a significant increment in the transcripts of chlorophyll biosynthesis genes (protochlorophyllide oxidoreductase [POR], chlorophyll a oxygenase [CAO]) and a reduction in the chlorophyll degradation genes (PPH, pheophorbide a oxygenase [PAO], and red chlorophyll catabolite reductase [RCCR]). In conclusion, P. indica has the potential to enhance the cucumber yield grown under moderate water stress rather than severe water stress by improving WUE and altering the activity levels of antioxidant enzymes and chlorophyll metabolism-related genes.
Full-text available
The present study was carried out to evaluate the nutritional, functional and quality parameters of different varieties of locally available cucumbers and their shelf stability. Cucumbers are botanically categorized as berries, which are available in many different sizes, shapes and colors. The most popular variety is the long smooth salad cucumber which has a smooth, dark-green skin. Some of the varieties of cucumbers available in local markets of India are English, Holenarasipur, Dotted, Zucchini, Gherkin, Armenian, Organic Zucchini, Organic Regular, Regular, Pranic healed cucumber. Pranic healing is an Ancient Science and Art of healing using Prana or life force. Different varieties of fresh cucumbers were studied for nutritional parameters: Moisture, vitamin-C; functional parameters: total phenols, antioxidant activity, and quality parameters: pH, brix and titrable acidity. All the 9 varieties were evaluated for the above mentioned parameters in different parts of cucumber viz, whole vegetable, peel and pulp. Highest moisture content was observed in English, Zucchini and Pranic healed cucumbers, and the lowest moisture content was found in two varieties, viz, Holenarasipur and dotted variety. Zucchini, organic variety had the highest vitamin C, antioxidant activity and total polyphenol content and was lowest found in Holenarisupur variety.
Full-text available
Tumor is a multifactorial sickness and consequently can be viably overwhelmed by a multi-constituently remedial strategy. Herbal extracts shows the example of such stratagem. However, less research have been carried out till date that portray the effect of different extraction techniques on the phyto compounds profile of plant extracts and its effect on anticancer activity. Cucumber (Cucumis sativus L.) is a member of the Cucurbitaceae family like melon, squash and pumpkins. It is a popular vegetable harvest in Indian customary medicine since olden times. It has potential lipid lowering and antioxidant activity and antidiabetic. In the present study, we have evaluated the anticancer prospective of methanolic and acetone extracts of Cucumis sativus (CSME) and (CSAE). Reported results show that (CSME) is rich in bioactive compounds shown anticancer activity with Cell lines of (IC50) with MCF 715.6 ± 1.3 and HeLa 28.2 ± 1. This study on the presence of cytotoxic from the Cucumis sativus L.), which have been further used in herbal formulations study as an anticancer activity. Our conclusion support additional in-depth study of this pharmacologic activity as an malignant tumor agent.
Full-text available
The present study deals with the antimicrobial activity and phytochemical screening of seeds extract of five plants of Cucurbitaceae family-Momordica charantia (Karella), Cucumis sativa (Cucumber), Praecitrullus fistulosus (Tinda), Cucurbita pepo (Kaddu), Lagenaria siceraria (loki) that are commonly available and readily consumed in India. Results of antimicrobial activity revealed that all the seeds extracts were very effective against Serratia marcescens , E. coli, Streptococcus thermophilous, Fusarium oxysporium, Trichoderma reesei while some extracts showed no inhibition against Aspergillus niger (Cucumis sativa), Candida albicans (Praecitrullus fistulosus, Cucurbita pepo, Lagenaria siceraria). Phytochemical analysis of these plants confirms the presence of various phytochemicals like tannins, cardiac glycosides, terpenoides, carbohydrates, resins, saponins and phytosterols. While other phtochemicals like alkaloids, flavonoids, glycosides, steroidal terpenes and phylobatamins were found to be absent in all the extracts. These plants can be a source of useful drugs but further studies are required to isolate the active component from the crude plant extract for proper drug development.
Full-text available
Present study deals with the demonstration of the antibacterial activity of very common medicinal plants of Pakistani origin i.e., Phyllantus emblica, Coriandrum sativum, Culinaris medic, Lawsonia alba and Cucumis sativus. The extracts were prepared in crude form by the use of hydro-alcoholic solution and were screened for antibacterial activity against various bacterial species by disk diffusion method. Assay was performed using clinical isolates of B. cereus, S. aureus, P. aeruginosa and E. coli. Crude extract of Phyllantus emblica fruit exhibited strong activity against standard cultures of all studied bacteria. Lawsonia alba showed good activity against standard cultures of all the used microorganisms. Coriandrum sativum was effective only against Bacillus cereus, while Cucumis sativus and Culinaris medic showed poor activity against Pseudomonas aeruginosa only. Hence, Phyllantus emblica exhibited strong antibacterial activity against a wide range of bacteria it means that Phyllantus emblica extract contains some compounds which have broad spectrum of bactericidal activity.
Full-text available
A study was conducted in the Department of Horticulture, Faculty of Agriculture, Gomal University, Dera Ismail Khan, NWFP, Pakistan during 2006. Six levels of nitrogen (0, 20, 40, 60, 80 and 100 kg/ha) were tried to see their effect on growth and yield of cucumber (Cucumis sativus L.). The results revealed that 100 kg N significantly increased fruit length (19.43 cm), fruit weight (152.2 g) and vine length (3.08 m) which are indirectly related to yield. However 80 kg N was found as the most economical dose for minimizing days to flowering (38.56), days to fruit setting (12.68) and days to fruit maturity (7.03) with higher number of fruits (15.22) and ultimately higher yield of cucumber (13.9 t/ha).
Full-text available
Ethanolic extracts of some fruits of Cucurbitaceae family such as Cucumis sativus (cucumber), Lagenaria siceraria (white pumpkin), Luffa acutangula (ridge gourd), Benincasa hispida (ash gourd), Citrullus lanatus (sweet melon) and Cucarbita maxima (pumpkin) have been studied for their hypoglycemic effects on alloxan induced diabetic rats (AIDRs). Screening results suggested that among the tested fruits the hypoglycemic potency follows: cucumber > white pumpkin > ridge gourd. These three fruit-extracts were further investigated for their hypoglycemic, hypolipidemic and glycogenesis effects. Cucumber, white pumpkin and ridge gourd extracts reduced blood glucose level by 67, 65 and 51%, respectively at 12 hours after single intraperitoneal injection; while reduced the low density lipoprotein (LDL) level to 13, 28 and 86%, respectively in AIDRs. The maximum reduction 87% was observed by cucumber extract. Cucumber, white pumpkin and ridge gourd extracts reduced total cholesterol level to 29, 15 and 38%, respectively comparing with the diabetic control group. Here the maximum reduction of 85% was observed by white pumpkin extract. Cucumber, white pumpkin and ridge gourd also reduced triglyceride levels to 72, 68 and 80%, respectively. Maximum reduction of 32% was observed by white pumpkin. Significant improvement of glycogenesis was also observed by ridge gourd extracts in AIDRs.
The study was aimed to evaluate the carminative and antacid properties of Cucumis sativus fruit pulp aqueous extract under simulated conditions. Fresh fruit pulp of Cucumis sativus was homogenized and dried under shade and thus mass obtained was powdered, weighed and subjected for the evaluation of carminative and antacid profile of the drug. Carminative & antacid properties of Cucumis sativa was evaluated using carbondioxide evolution method & Rossette Rice test. The Cucumis sativus extract showed significant results for carminative properties & antacid effect (P < 0.05) at different doses and the results obtained were comparable to that of standard NaHCO3. The results of the present study suggest that extract of C. sativa significantly neutralized acid and showed resistance against change in pH and also illustrate good carminative potential. The extract of C. sativa, has shown to possess significant carminative and antacid property.
Objective To elucidate the ameliorative effect of aqueous extract of fruit of Cucumis sativus (C. sativus) (CS) in acetic acid induced colitis in wistar rats.Methods The animals were administered with 2 mL acetic acid (4%) via intra rectal. The animals were divided into various treatment groups (n=6). Prednisolone was used as standard drug and C. sativus was administered at a dose of 100, 250 and 500 mg/kg p.o. The control group of animals received 1 mL of vehicle (distilled water). Ulcer area, ulcer index, spleen weight, colon weight to length ratio, macroscopic score, hematological parameters, colonic myeloperoxidase (MPO) and histological changes were recorded after the treatment regimen of 11 d.ResultsIntrarectal instillation of acetic acid caused enhanced ulcer area, ulcer index, spleen weight, colon weight to length ratio, colonic MPO and hematological parameters. Pretreatment with C. sativus for 7 d exhibited significant effect in lowering of ulcer area, ulcer index as well as neutrophil infiltration at a dose of 250 and 500 mg/kg in acetic acid induced colitis.Conclusion The present investigation demonstrates C. sativus is of potent therapeutic value in the amelioration of experimental colitis in laboratory animals by inhibiting the inflammatory mediator.