I. INITIAL, or NASAL and PHARYNGEAL + Intest. II. PULMONARY
ENOXAPARIN SC 40 mg every 24
h. In >70 Kg: 60 mg ev/ 24 h.
NATTOKINASE: 300mg/d.x 20d,or
LUMBROKINASE: 120mg/d. x 20d.
LYSINE 500mg at 7am, 4 and 10pm
FLUVOXAMINE50mg ev/12h x10d
ENOXAPARIN SC 0.5mg/kg ev/12h.
NATTOKINASE: 400mg/d x 20d, or
LUMBROKINASE: 160mg/d. x 20d.
LYSINE 1000mg 7am, 4 and 10pm 8d
CÚRCUMA 3000-4000 mg/d. x 14 d.
GARLIC: 5000 to 7000 mg/d. x 14 d
5) ENOXAPARIN AMP SC 40mg.
DOSE FOR CRITICAL CASES:
If the Sat. O2 drops to less than
80%: give 0.5 mg. x kg. of weight
every 8 hours x 2 to 3 days until
recovered the Sat. O2 > 80% and
changed to every 12 hours.
6) CYPROHEPTADINE start with
0.3 mg/kg/day, divide into doses
every 8 h x 3 d. Then 0.2 mg/kg.
7) FIBRINOLYTICS: EV or VO.
ACETYLSALICYLIC ACID (ASA)
300-500mg 1 time on the 1st day.
Ambulation at home, change
position every half hour during
the day, avoid crossing the legs,
flexion and extension exercises.
COVID-19:THERAPEUTIC PLAN AND POTENTIALTHERAPIES. Aguirre-Chang, Gustavo; Trujillo F, Aurora; CórdovaM,José Aníbal. February2021b
IVERMECTIN: 0.6mg x Kg of weight 2 times a day (breakfast and
lunch). Take until to 6 to 10 days after you have no symptoms.
SPIRONOLACTONE TB: 100mg every 12 or 24 hours for 8-10 d.
FENOFIBRATE TB: 160-200 mg/day x 14 days. And add one of
the following alternatives for 10 days: DUTASTERIDE 1mg/day,
or FINASTERIDE 10mg/day, or BICALUTAMIDE 150mg/day.
NEBULIZE* x 15 min. c/12 h x 3d. with: -HYDROGEN PEROXIDE,
at 3%, mix 3 ml with 3 ml of 0.9% NaCl; or Neb. with HCQ: grind
1 TB of 200 mg, pour into 8 ml of distilled water, or boiled cold.
IVERMECTIN: 0.4mg x Kg x doses, after
breakfast and dinner for 5 to 7 days.
If there is fever + than 24 hours, add 3rd
dose a day, and: NIFUROXAZIDE TB
give 400mg every 6 to 8 hoursx 3 to 15
days, according on severity. The
alternative is RIFAXIMINE TB 200 mg:
Give 400mg every 8 hours x 6-12 days.
FAMOTIDINE 60mg at 7.30am, 3pm, 11pm
x 7-14d.. If weighing >75kg give 80mg x3.
1) IVERMECTIN: 0.6mg/Kg x dose,
2-3 times a day. Take up to 9 to 15
days after you have no symptoms.
2) NIFUROXAZIDE 200mg 3TB ev/
8h x 6-9 d. >95 kg give 3TB e/ 6 h
3) NITAZOXANIDE or NICLOSAMI-
DA, TB 500 mg every 6h. x 9-15 d.
For <56 kg give 1TB every 8hours.
4) SPIRONOLACTONE 100 mg ev/
12 h. x 6 d., then 100 mg/d. x 8 d.
Days that are + hospitalized Requires ICU
The first 3 to 4 days there is no pulmonary involvement or this is little
Very HIGH Total Body Viral Load
VIRAL LOAD The Vir. load is estimated according to the response to treatment, 27-30 h. after the treat begins
100mg ev/12h x 7
d. >90kg ev/8h; or
500mg/d x 5 days
If there is fever, investig. Coinfection
Alte. Oral: CEFIXIME 400, LEVO 750,
MOXIFLOXACIN 400. IV: CEFTRIA-
XONE 2gr., CEFIPIME, MEROPENEN
Progress to Lungs, Intestines, Myocardium/Pericardium, Brain.
MEDIUM to HIGH ViralLo.
Investigate Kidney, Liver, others
Located in the nose and pharynx. The Variants frequently affect the intestines at this phase.
DEXAMETHASONE 4 mg. TB or
AMP: 6 to 8mg. x day x 2 - 5d, or
CYCLOSPORIN: 6 to 10 mg/kg/d.
in 2 doses, x 4-6d.,accord. resp.
400 mg/kg/d slow infusión. x 3d.
Use High Flow Nasal Cannula HFNC
ZINC: 200-250mgx day x 12d. Away from
food (11 am and / or 4 pm) and dairy.
Vit. D:60,-90,000 IU/d.x 6d. or 300,000/1d.
Vit. C: 2 gr every8 hours x 6 to 12days
Vit. A: 75,-100,000 IU x day x 3 d., do not
take x 4 days and repeat x 3 d. the same.
Sodium Bicarbonate: 1 sachet of Andrews
Salt or 1/2 teaspoon of Baking Soda in a
glass of water at 11am and 10pm x 3 days.
COLCHICINE TB 0.5 mg, 1 ev/12 h. x 15 d. If
you weigh >75 kg: give 2 TB in the morning.
N-ACETYLCYSTEINE 600 mg. sachet or TB.
2 sachet dissolved every 6-8h x 6 to 10days
BUDENOSIDE or CYCLESONIDE: 2 inhalati.
in the morning, noon and afternoon x 10 d.
QUERCETINE 1 TB 500mg every 8h. x 12d.
NIACIN (B3) 300mg x 2days, then 600mg/d.
OMEGA 3: TB 3000 mg/day x 15 d.
VIT.C: 50mg/kg. ev/ 8 or 12 h x 6 d.
VIT.B12 TB 3000 mcg/day x 8-12 d.
THYAMINE TB 600 mg/day x 8-12 d.
MELATONIN TB, before sleeping.
Increase from 3, to 6 and to 10mg.
MAGNESIUM TB 800mg/day x 14 d
SELENIUM TB 200mcg 2-3/d. x 30d
ASA TB : 300mg per day (100 mg after meals) x 4-9
d. For weigh more than 95kg give 500-600 mg/day.
Alternatives to ASA are: -CLOPIDOGREL 75mg/d. x
4-9d. If weigh is <56kg give 37.5mg/d. –GINGER: 1100
mg 3 times /day. For >95kg give 4400mg/day. DIPYRI-
DAMOLE: 1 TB 75 mg 3-4 times/day, away from food.
IVERMECTIN: 0.4 mg per Kg. of
weight x dose a day, after lunch
or dinner for 3 to 4 days. If you
have a fever over 38°C for more
than 12 hrs or semiliquid stool,
add the 2nd dose in the day.
Additional Hydration: 1-2 lt./day.
Nasal Washes: 3-4 times /d. with
a 20 ml syringe with 1 glass of
water with 1/2 teaspoon of salt.
Avoid:coffee, alcohol; nuts, peanuts,
almonds, pecans; orange, lemon,
tangerine, banana, chocolate; chili;
seeds, oats, wheat, corn; tomato,
cabbage; sausages; fish, shellfish.
Consume more:turkey, chicken, egg,
beef; mango; potato, quinoa; yoghurt
Do not use PARACETAMOL. Only if
the fever is> 38.5 °Cgive antipyretics
Rapid response to treatment, w/
improvement from 97 to 100% =
Initial Pulmonary Edema,
Mod/Sev ARDS, SIRS, Thrombo-
embolic disease, Myocarditis, in-
vesti.Heart-Renal failure, Enceph.
Gargle: 4-5 times a day. Mix 10 ml of cold boiled water with 5 ml of Hydrogen
peroxide of 3 %, 10vol. Or w/ 0.05% Cetylpyridinium Chloride,10ml undiluted.
Give IVERMECTIN to Contacts: 0.4 mg for Kg of weight for 3 continued days.
In Men aged over 70 years give 5 days. In Caregivers give 6 continued days.
Add to what is
TB 500 mg ev/8h x
8-14 d. If weigh is
>90kg give ev/6h.
FCO. 8 mg (5ml)
every 8 h x 6-8 d.
Partial response to treatment, 25 to 96
% improvement = MEDIUM Viral Load.
But if it affects the intestines, it is high.
HIGH and Persis-
tent Viral Load
Moderate ARDS, Pulmonary Coa-
gate Myocarditis/Pericard., Enceph.
Response to treat-
HIGH VL: Lungs, Intestines, Heart.
For Pulmonary Edema :
put in Prone position.
Restrict liquids, salt, do
not give Sodium Chloride:
NaCl (yes Dextrose 5%).
Day 1 Day 2 Day 3 Day 4 Day 5 Day 6 Day 7 8 9 10 11 12 13 14
* When nebulizing, take into account that aerosols will be generated, which increases the risk of contagion to other people. When doing it at home, teach the patient how to turn off the nebulization, and that there is no other person in the environment while nebulizing.