Differences in the establishment of the leafhoppers Empoasca devastans and E. kerri motti on different plants are determined by an interaction of the following chief types of their responses in six main stages: (1) Orientation, (2) Feeding, (3) Metabolic utilization of the ingested food determining its nutritive value, (4) Growth, (5) Survival and egg-production, (6) Oviposition. Both the leafhoppers showed equally high attraction and proboscis response to all the six test plants, namely, Gossypium hirsutum, G. herbaceum, G. arboreum, Solanum melongena, S. tuberosum, and Ricinus communis. The quantity and nutritive value of the food ingested by E. devastans decreased in the order: G. hirsutum, S. melongena, S. tuberosum, G. herbaceum, G. arboreum, and R. communis. The growth, particularly in respect of moulting/metamorphosis to adult, also decreased in the same order except that S. melongena was superior to G. hirsutum. But, the suitability of the plants for adult survival decreased in the order: S. tuberosum, S. melongena, G. hirsutum, G. herbaceum, G. arboreum, R. communis. The egg-production and ovipositional response decreased in the order: S. melongena, G. hirsutum, S. tuberosum, G. herbaceum, G. arboreum, R. communis. The interaction of the above responses would render S. melongena most suitable for the establishment of E. devastans and the suitability of the remaining plants would decrease in the order: G. hirsutum, S. tuberosum, G. herbaceum, and G. arboreum, while R. communis would be completely unsuitable.