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© 2020 Indian Journal of Ophthalmology | Published by Wolters Kluwer - Medknow
Original Article
Clinical prole and prevalence of conjunctivitis in mild COVID-19 patients in
a tertiary care COVID-19 hospital: A retrospective cross-sectional study
Sindhuja K, Neiwete Lomi, Mohamed I Asif, Radhika Tandon
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DOI:
10.4103/ijo.IJO_1319_20
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Purpose:
Methods:
th
th
Results:
Conclusion:
Key words:
th
05‑May‑2020 Revision: 26‑May‑2020
06‑Jun‑2020 24‑Jul‑2020
The main symptoms of
appropriate measures while examining a patient with
Methods
thth
Cite this article as: Sindhuja K, Lomi N, Asif MI, Tandon R. Clinical prole
and prevalence of conjunctivitis in mild COVID-19 patients in a tertiary care
COVID-19 hospital: A retrospective cross-sectional study. Indian J Ophthalmol
2020;68:1546-50.
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et al 1547
P
Results
Demographic data of patients
the 3rd week of admission and few patients (13 patients in 1st
week and 15 patients in 2nd
Data regarding systemic history
Data regarding ocular history
1
2]
3
during 1st
nd
patients in 3rd
st
one patient during 3rd
Data regarding patients with conjunctival congestion sug-
gestive of conjunctivitis
during 1st
nd
patients in 3rd
time of admission and one patient developed sore throat on
7th
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1548 Volume 68 Issue 8
Discussion
4
Table2: Characteristics of patients with conjunctival congestion
Patient 1 2 3 4 5 678
Age(years) 24 51 61 61 27 29 24 52
Sex Male Male Male Male Male Male Male Male
Exposure history Religious
gathering
Religious
gathering
Religious
gathering
Religious
gathering
Contact from
positive nonfamily
members
Religious
gathering
Religious
gathering
Religious
gathering
Systemic
symptoms
Cough Fever and
cough
Sore throat Sore throat Sore throat
manifested on 7th
day
No No Cough and
Rhinorrhea
Duration of
systemic symptom
at the time of
admission
5days 4days 2days 2days Asymptomatic on
admission
Asymptomatic Asymptomatic 2days
Systemic illness Nil Nil Nil Diabetes Nil Nil No Diabetes and
hypertension
Ocular complaints H/O
Conjunctival
Congestion
and watering
for 2days
H/O
Conjunctival
congestion
for 2days
RE
conjunctival
congestion
Conjunctival
congestion
Conjunctival
congestion,
watering, and
Itching, photophobia
and periorbital rash
Conjunctival
congestion
Conj.
Redness
on and off
2weeks
Conj.
Redness on
and off and
watering for
2weeks
Day of
manifestation
of conjunctival
congestion after
admission
7th day(1st
week)
2nd day(1st
week)
19th day(3rd
week)
18th day(3rd
week)
5th day(1st week) 18th day(3rd
week)
2nd day(1st
week)
2nd day(1st
week)
Manifestation
of conjunctival
congestion after
onset of systemic
symptoms
12th day(2nd
week)
6th day(1st
week)
21st day(3rd
week)
20th day(3rd
week)
‑ ‑ ‑ 4th day
(1st week)
Hand eye contact Yes No No Yes Yes No No No
h/o use of goggles/
glasses
No No Yes No No No No Yes
Examination
Conjunctival
congestion
No No Diffuse Diffuse Diffuse Diffuse No No
Associated findings Lid edema
Periorbital rash
Table1: Ocular symptoms of patients(12/127)
Symptom No of patients Percentage
Conjunctival congestion 9 7.08
Burning sensation 10.79
Watering 1 0.79
Painful eyelid swelling 10.79
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et al
studies 5
Conclusion
Financial support and sponsorship
Conicts of interest
Table4: Percentage of patients who developed
conjunctival congestion with various associations
Conjunctivitis P
Yes No
H/O Hand‑eye contact
Yes 3 47 >0.999
No 5 72
Systemic illness
Yes 2 18 0.611
No 6101
No use of eye goggles or glasses
Yes 6103 0.316
No 2 16
Upper respiratory tract infection
Yes 642 0.052*
No 2 77
P<0.05 is considered as significant
Table3: Characteristics of patients with other ocular manifestations
Patient 9 10 11
Age(years) 48 59 26
Sex Female Male Male
Contact history Contact from positive
nonfamily member
Contact from positive
Nonfamily member
Contact from positive nonfamily member
COVID‑19‑related systemic symptoms No No No
Systemic illness Hypertension, hypothyroidism HTN Nil
Ocular complaints Burning sensation for 1week Watering for 10days Painful swelling in left lower eyelid for 2days
Day of manifestation of ocular
symptom after admission
2nd day 2nd day 7th day
Hand‑eye contact No Yes No
H/O use of goggles Yes Yes No
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1550 Volume 68 Issue 8
Table5: Comparison of prevalence of conjunctival congestion between various studies
Study name Month and
year of
publication
Sample
size
Patients with
conjunctival
congestion
Patients with
conjunctival
swab positive
% patients with
conjunctival
congestion
Guan etal.[3] conducted a study to find the clinical
characteristics of coronavirus 2019 disease in china.
Feb 2020 1099 9 Not done 0.81%
Xia etal.[4] conducted a study to evaluate
coronavirus in tears and conjunctival secretions of
patients with SARS‑CoV‑2 infection
Feb 2020 30 1 1 3.33%
Chen etal.[5] studied ocular manifestation and
clinical characteristics of 534cases of COVID‑19 in
China: ACross‑sectional study
March 2020 534 25 not done 4.68%
Wu etal.[6] studied characteristics of ocular findings
of patients with COVID‑19 in Hubei Province, China
March 2020 38 12* 231.57%
Loffredo etal.[7] did a meta‑analysis: Conjunctivitis
and COVID‑19
April 2020 1167 ‑1.1% (3% in severe,
0.7% in nonsevere)
Hong etal.[9] conducted a study to evaluate the
ocular symptoms and tropism of SARS‑CoV‑2 in
patients confirmed with COVID‑19.
April 2020 56 2 1 3.57%
*In study conducted by Wu etal., among 12patients with ocular symptoms suggestive of conjunctivitis, 10patients(26.31%) had conjunctival congestion. The
study included more severe cases of COVID‑19 positives
References
et al
et al
et al
et al
et al
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