ArticlePDF Available

Comparing Meniscectomy and Meniscal Repair: A Matched Cohort Analysis Utilizing a National Insurance Database

Authors:

Abstract and Figures

Background Meniscal repair leads to improved patient outcomes compared with meniscectomy in small case series. Purpose To compare the reoperation rates, 30-day complication rates, and cost differences between meniscectomy and meniscal repair in a large insurance database. Study Design Cohort study; Level of evidence, 3. Methods A national insurance database was queried for patients who underwent meniscectomy (Current Procedural Terminology [CPT] code 29880 or 29881) or meniscal repair (CPT code 29882 or 29883) in the outpatient setting and who had a minimum 2-year follow-up. Patients without confirmed laterality and patients who underwent concomitant ligament reconstruction were excluded. Reoperation was defined by ipsilateral knee procedure after the index surgery. The 30-day postoperative complication rates were assessed using the International Classification of Diseases, 9th Revision, Clinical Modification codes. The cost of the procedures per patient was calculated. Propensity score matching was utilized to create matched cohorts with similar characteristics. Statistical comparisons of cohort characteristics, reoperations, postoperative complications, and payments were made. All P values were reported with significance set at P < .05. Results A total of 27,580 patients (22,064 meniscectomy and 5516 meniscal repair; mean age, 29.9 ± 15.1 years; 41.2% female) were included in this study with a mean follow-up of 45.6 ± 21.0 months. The matched groups were similar with regard to characteristics and comorbidities. There were significantly more patients who required reoperation after index meniscectomy compared with meniscal repair postoperatively (5.3% vs 2.1%; P < .001). Patients undergoing meniscectomy were also significantly more likely to undergo any ipsilateral meniscal surgery ( P < .001), meniscal transplantation ( P = .005), or total knee arthroplasty ( P = .001) postoperatively. There was a significantly higher overall 30-day complication rate after meniscal repair (1.2%) compared with meniscectomy (0.82%; P = .011). The total day-of-surgery payments was significantly higher in the repair group compared with the meniscectomy group ($7094 vs $5423; P < .001). Conclusion Meniscal repair leads to significantly lower rates of reoperation and higher rates of early complications with a higher total cost compared with meniscectomy in a large database study.
Content may be subject to copyright.
Comparing Meniscectomy
and Meniscal Repair
A Matched Cohort Analysis Utilizing
a National Insurance Database
Kyle R. Sochacki,
*
y
MD, Kunal Varshneya,
y
BS, Jacob G. Calcei,
y
MD, Marc R. Safran,
y
MD,
Geoffrey D. Abrams,
y
MD, Joseph Donahue,
y
MD, and Seth L. Sherman,
y
MD
Investigation performed at Department of Orthopaedic Surgery,
Stanford University Medical Center, Palo Alto, California, USA
Background: Meniscal repair leads to improved patient outcomes compared with meniscectomy in small case series.
Purpose: To compare the reoperation rates, 30-day complication rates, and cost differences between meniscectomy and
meniscal repair in a large insurance database.
Study Design: Cohort study; Level of evidence, 3.
Methods: A national insurance database was queried for patients who underwent meniscectomy (Current Procedural Terminol-
ogy [CPT] code 29880 or 29881) or meniscal repair (CPT code 29882 or 29883) in the outpatient setting and who had a minimum
2-year follow-up. Patients without confirmed laterality and patients who underwent concomitant ligament reconstruction were
excluded. Reoperation was defined by ipsilateral knee procedure after the index surgery. The 30-day postoperative complication
rates were assessed using the International Classification of Diseases, 9th Revision, Clinical Modification codes. The cost of the
procedures per patient was calculated. Propensity score matching was utilized to create matched cohorts with similar character-
istics. Statistical comparisons of cohort characteristics, reoperations, postoperative complications, and payments were made. All
Pvalues were reported with significance set at P\.05.
Results: A total of 27,580 patients (22,064 meniscectomy and 5516 meniscal repair; mean age, 29.9 615.1 years; 41.2% female)
were included in this study with a mean follow-up of 45.6 621.0 months. The matched groups were similar with regard to char-
acteristics and comorbidities. There were significantly more patients who required reoperation after index meniscectomy com-
pared with meniscal repair postoperatively (5.3% vs 2.1%; P\.001). Patients undergoing meniscectomy were also
significantly more likely to undergo any ipsilateral meniscal surgery (P\.001), meniscal transplantation (P= .005), or total
knee arthroplasty (P= .001) postoperatively. There was a significantly higher overall 30-day complication rate after meniscal repair
(1.2%) compared with meniscectomy (0.82%; P= .011). The total day-of-surgery payments was significantly higher in the repair
group compared with the meniscectomy group ($7094 vs $5423; P\.001).
Conclusion: Meniscal repair leads to significantly lower rates of reoperation and higher rates of early complications with a higher
total cost compared with meniscectomy in a large database study.
Keywords: meniscectomy; meniscal repair; reoperations; database
The meniscus functions to provide joint stability, congruency,
proprioception, and force distribution across the knee by con-
verting compressive forces into hoop stresses.
22,23
Meniscal
injury is one of the most common conditions treated by ortho-
paedic surgeons, with up to 61% of patients demonstrating
meniscal pathology on imaging.
12,15
Once the meniscus is
injured, the patient’s loss of meniscal integrity leads to
altered mechanics and joint forces with resultant increased
contact pressures on the articular cartilage.
16-18,26
This man-
ifests as pain, swelling, locking, or other mechanical symp-
toms. After the failure of nonoperative treatment, the
historical treatment of choice has been arthroscopic partial
meniscectomy to improve symptoms in these patients. How-
ever, biomechanical studies have shown that meniscectomy
can lead to increased contact pressures of up to 80% to 90%
with increasing amounts of meniscus resected.
16-18,26
Addi-
tionally, partial meniscectomy can also lead to changes in
gait kinematics that place even more stress on the tibiofe-
moral surface.
38
This results in the majority of these patients
The American Journal of Sports Medicine
1–7
DOI: 10.1177/0363546520935453
Ó2020 The Author(s)
1
demonstrating articular cartilage degenerative changes and
osteoarthritis less than 10 years after surgery.
28,35
Now that the long-term morbidities associated with par-
tial meniscectomy have been identified, meniscal preserva-
tion has been increasingly emphasized.
2
Biomechanical
studies have demonstrated that meniscal repair restores
the tibiofemoral contact pressures to levels similar to those
of an intact meniscus, while partial meniscectomy leads to
significantly higher values.
6,7,20,25,26
Clinical studies have
also found there to be significantly improved patient-reported
outcomes and decreased progression to osteoarthritis rate
after meniscal repair, but with a relatively high reopera-
tion.
11,27,37,40
However, there are very few studies that
directly compare meniscectomy with meniscal repair.
The purpose of this study was to compare the reopera-
tion rates, 30-day complication rates, and cost differences
between meniscectomy and meniscal repair in a large
insurance database. The authors hypothesized that there
would be (1) significantly higher reoperation rates for
meniscal repair, (2) no difference in 30-day complications
rates between groups, and (3) significantly higher cost in
patients undergoing meniscal repair.
METHODS
The MarketScan Commercial Claims and Encounters data-
base (Truven Health Analytics) from January 1, 2007, to
December 31, 2016, was used for this study. This database
is a collection of commercial inpatient, outpatient, and phar-
maceutical claims of more than 75 million employees, retir-
ees, and dependents representing a substantial portion of
the U.S. population covered by employer-sponsored insur-
ance. MarketScan contains 53 million inpatient records,
40 million with employer-sponsored insurance, 3.7 million
with Medicare Part B, and 6.8 million on Medicaid, for
a total of more than 28 billion patient records. Only outpa-
tient records in MarketScan were queried for this study.
The MarketScan database contains International Classifica-
tion of Diseases, 9th Revision, Clinical Modification (ICD-9-
CM) and 10th Revision, Clinical Modification (ICD-10-CM),
Current Procedural Terminology (CPT), and Diagnosis
Related Group codes, as well as National Drug Codes.
Patients who underwent meniscectomy (CPT code
29880 or 29881) or meniscal repair (CPT code 29882 or
29883) in the outpatient setting with a minimum 2-year
follow-up were queried in the database. Records of the
index surgery were reviewed for analysis. Patients without
a CPT modifier for laterality (left or right) were excluded.
Patients who had both procedures were excluded, thus
making the cohorts mutually exclusive. Additionally,
patients undergoing concomitant ligament reconstruction
procedures were excluded. Patient-level variables, includ-
ing age at time of surgery, sex, and comorbidities (obesity,
myocardial infarction, congestive heart failure, peripheral
vascular disease, cerebrovascular disease, dementia,
chronic pulmonary disease, rheumatic disease, peptic ulcer
disease, liver disease, diabetes, hemiplegia, renal disease,
malignancy, AIDS/HIV, tobacco use), were recorded based
on claims data (Table 1).
The primary outcome measure was rate of ipsilateral
reoperation. Reoperation was defined by ipsilateral menis-
cectomy (CPT code 29880 or 29881), meniscal repair (CPT
code 29882 or 29883), meniscal allograft transplantation
(CPT code 29868), synovectomy (CPT code 29875 or
29876), chondroplasty (CPT code 29877), manipulation
under anesthesia (CPT code 27570), lysis of adhesions
(CPT code 29884), arthroscopic loose body removal (CPT
code 29874), debridement for infection (CPT code 27301,
27303, 27310, or 29871), osteotomy (CPT code 27457 or
27450), partial knee replacement (CPT code 27446), or
total knee replacement (CPT code 27447) that occurred
after the index surgery date. Ipsilateral reoperation was
queried using CPT codes and the CPT modifiers for later-
ality to ensure that the procedures were reoperations and
not contralateral procedures. The time period for potential
reoperation was up to 9 years postoperatively, depending
on when the index surgery was performed.
The 30-day postoperative complication rates were also
assessed for both cohorts using the ICD-9-CM codes. These
included bursitis, anemia, knee dislocation, infection, nerve
injury, neurologic complications, cardiac complications, het-
erotopic ossification, sepsis, wound complications, deep vein
thrombosis, pulmonary embolus, hematoma, pulmonary
complications, urinary tract infection, and delirium.
The cost of the procedure per patient was calculated
using the Diagnosis Related Group system. This included
the entire reimbursement by the insurer on the day of sur-
gery. The cumulative cost of the procedure per patient was
also calculated at 9 months and 2 years postoperatively,
including the cost of reoperations.
*
Address correspondence to Kyle R. Sochacki, MD, Department of Orthopaedic Surgery, Stanford University Medical Center, 450 Broadway Street MC
6342, Redwood City, CA 94063, USA (email: kylersochackimd@gmail.com).
y
Department of Orthopaedic Surgery, Stanford University Medical Center, Palo Alto, California, USA.
Submitted January 6, 2020; accepted April 27, 2020.
One or more of the authors has declared the following potential conflict of interest or source of funding: M.R.S. holds stock or stock options in Biomi-
medica; receives royalties from DJ Orthopaedics, Smith & Nephew, and Stryker; has received consulting fees from Medacta; and has received research
support and speaking fees from Smith & Nephew. G.D.A. has received consulting fees from Cytonics Inc, Fidia Pharma, RubiconMD, and Sideline Sports
Doc; other financial or material support from Arthrex Inc and Stryker; and holds stock or stock options in Cytonics Inc. J.D. holds stock or stock options in
Stabilynx; and has received education payments from Arthrex, consulting fees from DePuy Synthes, and hospitality payments from Evolution Surgical,
Medical Device Business Services, and Stabilynx Inc. S.L.S. has received consulting fees from Arthrex Inc, Ceterix Orthopaedics, CONMED Linvatec, Flex-
ion Therapeutics, GLG Consulting, JRF Ortho, Moximed, Olympus, and Vericel; research support from Arthrex Inc; and education payments from Elite
Orthopedics. AOSSM checks author disclosures against the Open Payments Database (OPD). AOSSM has not conducted an independent investigation
on the OPD and disclaims any liability or responsibility relating thereto.
2Sochacki et al The American Journal of Sports Medicine
To minimize the effect of potential confounding on the
direct comparison of patients undergoing the 2 procedures,
a propensity score match procedure was utilized. A greedy
nearest-neighbor algorithm was employed to match
patient cohorts with a 2:1 meniscectomy to repair ratio.
A caliper of 0.01 was utilized in the match, and replace-
ment of patients in the algorithm was not allowed. All
baseline characteristics were input into the algorithm,
leading to the matched covariates having no statistically
significant differences.
A propensity score is the probability a patient may be
placed in a group (meniscal repair or meniscectomy) based
on the patient’s characteristics and comorbidity status (all
covariates from Table 1).
4
When patients are matched on
their propensity scores (based on the covariates incorpo-
rated into the scores), patients will have statistically insig-
nificant differences in their likelihood to be placed in either
group (in this case, to receive a meniscectomy or meniscal
repair).
3
A greedy nearest-neighbor algorithm was
employed to match patient cohorts with a 2:1 meniscec-
tomy to repair ratio. Although there are many algorithms
available to match with, greedy nearest neighbor is pre-
ferred as it matches patients based on closest, ‘‘nearest’’
propensity scores within the caliper (maximal difference
allowed between a patient’s propensity scores to match).
3
Statistical comparisons of cohort characteristics, reoper-
ations, postoperative complications, and payments were
made. The significance of differences in means of continu-
ous variables between the 2 groups was determined using
the Student ttest. The differences in categorical variables
between groups was determined using the chi-square test.
Percentages in this study were a representation of propor-
tion of the cohort. All Pvalues were reported with signifi-
cance set at P\.05.
As this study includes only analysis of secondary de-
identified data, it was not considered human subject
research and was given exempt status approval by our
institutional review board at our institution.
RESULTS
A total of 27,580 patients (22,064 meniscectomy and 5516
meniscal repair; mean age, 29.9 615.1 years old; 41.2%
female) were included in this study with a mean follow-up
of 45.6 621.0 months (Table 1). Before matching, patients
in the meniscectomy cohort were significantly older, more
often female, and had significantly more comorbidities (P\
.001 for all) (Table 1). After matching, the groups were simi-
lar with regard to characteristics and comorbidities.
There were significantly more patients who required
reoperation after index meniscectomy compared with
meniscal repair postoperatively (5.3% vs 2.1%; P\.001)
(Table 2). Patients undergoing meniscectomy were also sig-
nificantly more likely to undergo any ipsilateral meniscal
surgery (P\.001), meniscal transplantation (P= .005),
or total knee arthroplasty (P= .001) up to a maximum of
9 years postoperatively compared with those undergoing
meniscal repair.
There were significantly higher overall 30-day compli-
cation rates after meniscal repair (1.2%) compared with
meniscectomy (0.82%; P= .011) (Table 3). Patients under-
going meniscal repair had significantly higher infection
(0.4% vs 0.2%; P= .016) and deep vein thrombosis (0.3%
vs 0.1%; P\.001) rates compared with those undergoing
meniscectomy.
The total day-of-surgery payments were significantly
higher in the repair group compared with the meniscec-
tomy group ($7094 vs $5423; P\.001) (Table 4). This trend
occurred at all time points in the study, with a total 2-year
cost of repair at $15,203. This is compared with the 2-year
cost of meniscectomy of $12,594 (P\.001).
DISCUSSION
Our data showed that meniscal repair leads to significantly
lower reoperation, meniscal surgery, meniscal transplanta-
tion, and total knee arthroplasty rates compared with
TABLE 1
Patient Characteristics
a
Non–Propensity Score Matched Propensity Score Matched
Meniscectomy
(n = 562,251)
Meniscal Repair
(n = 13,780) PValue
Meniscectomy
(n = 22,064)
Meniscal Repair
(n = 5516) PValue
Age, mean 6SD 49.1 611.6 29.6 614.5 \.001
b
30.0 615.2 29.9 614.8 .784
Female 256,861 (45.7) 5439 (39.5) \.001
b
9107 (41.3) 2245 (40.7) .437
Hypertension 209,795 (37.3) 1670 (12.1) \.001
b
2839 (12.9) 702 (12.7) .780
Diabetes 70,828 (12.6) 541 (3.9) \.001
b
823 (3.7) 227 (4.1) .181
Hyperlipidemia 183,636 (32.7) 1480 (10.7) \.001
b
3415 (15.5) 608 (11.0) .870
Cerebrovascular accident 18,374 (3.3) 155 (1.1) \.001
b
232 (1.1) 64 (1.2) .483
Tobacco use 46,060 (8.2) 801 (5.8) \.001
b
1113 (5.0) 296 (5.4) .332
Tissue disorder 3796 (0.7) 43 (0.3) \.001
b
39 (0.2) 13 (0.2) .367
Obesity 73,402 (13.1) 840 (6.1) \.001
b
1129 (5.1) 286 (5.2) .838
Mean CCI 0.37 0.14 \.001
b
0.12 0.13 .112
Mean follow-up, mo 25.2 623.3 23.4 622.9 \.001
b
45.6 620.9 45.4 621.1 .413
a
Data are presented as n (%) unless otherwise indicated. CCI, Charlson Comorbidity Index.
b
Statistically significant.
AJSM Vol. XX, No. X, XXXX Meniscectomy Has Higher Reoperation Rate Than Repair 3
meniscectomy at final follow-up. However, there were higher
rates of complications and a higher total cost with meniscal
repair compared with meniscectomy. This partially confirms
the authors’ hypotheses.
Before matching, patients in the meniscectomy cohort
were significantly older and had significantly more comor-
bidities (P\.001 for all). This is likely because of a long-
held belief that older patients have worse outcomes
compared with younger patients after meniscal repair.
8,10
However, more recent studies have suggested that age
may not play as significant a role in outcomes as previously
believed.
21,31,36
Additionally, the role of obesity in meniscal
repair outcomes has conflicting results in the literature,
with a study by Brophy et al
9
showing significantly worse
outcomes and higher rates of subsequent surgery rates in
obese patients undergoing posterior medial root repairs.
TABLE 2
Reoperations
a
Meniscectomy (n = 22,064) Meniscal Repair (n = 5516) PValue
Overall reoperation rate 1175 (5.3) 116 (2.1) \.001
b
Meniscectomy 832 (3.8) 0 (0.0) ..999
b
Meniscal repair 0 (0.0) 120 (2.2) \.001
b
Meniscal transplantation 40 (0.2) 1 (0.0) .005
b
Synovectomy 321 (1.5) 74 (1.4) .595
Chondroplasty 102 (0.5) 27 (0.5) .791
Manipulation under anesthesia 27 (0.1) 7 (0.1) .932
Lysis of adhesions 21 (0.1) 13 (0.2) .008
b
Loose body removal 26 (0.1) 9 (0.2) .398
Debridement for infection 8 (0.0) 1 (0.0) .791
Osteotomy—HTO 7 (0.0) 1 (0.0) .596
Osteotomy—DFO 7 (0.0) 3 (0.1) .429
UKA 16 (0.1) 5 (0.1) .662
TKA 321 (1.5) 49 (0.9) .001
b
a
Data are presented as n (%). DFO, distal femoral osteotomy; HTO, high tibial osteotomy; TKA, total knee arthroplasty; UKA, unicom-
partmental knee arthroplasty.
b
Statistically significant.
TABLE 3
30-Day Complications
a
Meniscectomy (n = 22,064) Meniscal Repair (n = 5516) PValue
Any complication 181 (0.82) 68 (1.2) .011
b
Bursitis 8 (0.0) 4 (0.1) .248
Deficiency anemia 72 (0.3) 20 (0.4) .716
Infection 45 (0.2) 21 (0.4) .016
b
Nerve injury 1 (0.0) 1 (0.0) .289
Sepsis 4 (0.0) 1 (0.0) ..999
Wound complication 12 (0.1) 1 (0.0) .267
Deep vein thrombosis 27 (0.1) 17 (0.3) \.001
b
Pulmonary embolus 0 (0.0) 0 (0.0) ..999
Hematoma 17 (0.1) 5 (0.1) .749
a
Data are presented as n (%).
b
Statistically significant.
TABLE 4
Procedure Payments
Meniscectomy (n = 22,064) Meniscal Repair (n = 5516) PValue
Day-of-surgery payments $5423 $7094 \.001
a
Total payments
9 mo $8348 $10,898 \.001
a
2 y $12,594 $15,203 \.001
a
a
Statistically significant.
4Sochacki et al The American Journal of Sports Medicine
However, a study by Sommerfeldt et al
34
found that obese
patients did not have a higher risk of failure compared
with normal weight patients when considering all menis-
cus tear patterns. This leads the current authors to believe
that tear location, tear pattern, tear size, concomitant sur-
geries, and preexisting joint degeneration may play a larger
role in patient outcomes than patient characteristics or
comorbid conditions.
After controlling for these patient characteristic con-
founders and creating matched cohorts, patients undergo-
ing meniscectomy were significantly more likely to
undergo reoperation (5.3% vs 2.1%) compared with those
undergoing meniscal repair. However, previous non-
matched studies found that meniscal repair leads to signif-
icantly higher reoperation rates in both the short and the
long term, with some studies reporting reoperation rates
of 20.7% versus 3.9%.
27,37
This is surprising given the fact
that patients undergoing meniscectomy had worse patient-
reported outcome scores and were more likely to progress
to knee osteoarthritis compared with those undergoing
meniscal repair.
27
It is also important to note that the revi-
sions and/or reoperation rates would likely be even higher if
there had been a longer follow-up.
The difference in reoperation rates from those reported
in previous studies is likely because of the lack of matched
cohorts and the resultant inability to control for confound-
ing variables. Additionally, the number of patients
included in these studies likely plays a large role. Most of
the studies included in the review by Paxton et al
27
were
small case series, with the largest study including 198
patients. This is compared with the current study of
27,580 patients. These small case series represent selec-
tion bias in which the majority of the peer-reviewed litera-
ture is from meniscus experts who work at tertiary referral
centers, making them likely to encounter more complex
tear patterns. Additionally, patients with complications
or poor outcomes are more likely to return for follow-ups
than patients who are doing well, leading to a higher pro-
portion of patients with unfavorable outcomes meeting the
minimum follow-up requirement for publication.
Patients undergoing meniscectomy were also signifi-
cantly more likely to undergo meniscal transplantation
(0.2% vs 0.0%; P= .0049) and total knee arthroplasty
(1.5% vs 0.9%; P= .0011) up to a maximum of 9 years post-
operatively compared with those undergoing meniscal
repair. This further illustrates the need for meniscal pres-
ervation at index surgery whenever possible, with both
meniscal transplantation and knee arthroplasty consid-
ered salvage procedures in this young population. Once
the patient becomes meniscus-deficient, the outcomes after
meniscal transplantation are worse than if the patient
underwent meniscal repair at their index procedure.
39
The increased rate of knee arthroplasty after meniscec-
tomy further confirms the results of previous studies, with
up to 51.5% of patients requiring knee arthroplasty after
meniscectomy compared with 33.5% after meniscal repair
at the 10-year follow-up.
1,5,13,29
Abram et al
1
utilized the
National Health Service database of England to determine
that 0.67% of patients who underwent meniscectomy
between the ages of 20 and 39 years required subsequent
knee arthroplasty. This is similar to the current study,
with 1.5% requiring total knee arthroplasty in similar
aged patients with similar follow-up. However, Abram
et al did not compare the differences in arthroplasty rates
between meniscectomy and meniscal repair in this young
patient population. It is also possible that meniscectomy
was perhaps not indicated at the time of surgery and the
patient may have been better managed with nonoperative
care or knee arthroplasty at the time of the index proce-
dure. This is supported by previous studies demonstrating
that patients undergoing meniscectomy did no better than
control groups, especially in degenerative knees.
24,30
Despite a higher reoperation rate, meniscectomy was
associated with lower 30-day complication rates compared
with meniscal repair (0.82% vs 1.2%). These rates are simi-
lar to the previously reported complications after meniscec-
tomy and meniscal repair.
19,33,37
A recent systematic
review demonstrated that patients undergoing meniscal
repair had higher complication rates than those with menis-
cectomy (12.9% vs 1.3%).
32
This was because of the inclusion
of knee pain and revision surgery as complications. Knee
pain was not a codable complication and may not have
been identified in the present study, while reoperation was
considered separate from complications. After removing
these confounders, the complication rates become more sim-
ilar between groups. Additional complications specific to
meniscal repair include device failure, device breakage, or
reactive synovitis to the repair material.
19
However, these
are also not codable complications and may lead to an under-
estimation of the complication rate after meniscal repair.
The total day-of-surgery, 9-month, and 2-year payments
were significantly higher in the repair group compared
with meniscectomy. The higher cost in the meniscal repair
group is likely because of initial differences in implant cost
and higher surgeon reimbursement for the procedure.
Meniscal repair also demonstrated a higher day-of-surgery
cost in previous studies investigating the cost-effectiveness
of meniscectomy versus repair.
13,14
However, at 10 and 30
years postoperatively, meniscal repair became more cost-
effective because of reduced rates of total knee arthro-
plasty in a Markov model.
13,14
It is likely that the current
study failed to follow this same trend because of the
shorter follow-up and a younger patient population. This
leads to a relatively low incidence of knee arthroplasty
compared with older patients undergoing meniscectomy
or meniscal repair in other studies.
1,5,13,29
There are some limitations to this study that are inher-
ent to all studies that use large databases. The analysis is
dependent upon the accuracy of the ICD and CPT codes
reported. As such, inaccuracies, miscoding, or noncoding
by physicians is a potential source of error. Additionally,
patients can change insurance providers and, therefore,
leave the database. However, this was controlled for
through inclusion of patients with a minimum 2-year fol-
low-up. However, this minimum follow-up likely excluded
a large number of patients who changed or lost their insur-
ance, creating a potential population bias. It is also possi-
ble that the database is not a true representation of the
population receiving health care in the United States.
However, through the inclusion of outpatient records
AJSM Vol. XX, No. X, XXXX Meniscectomy Has Higher Reoperation Rate Than Repair 5
from patients with commercial insurance, Medicare, and
Medicaid, the current study is more inclusive. Addition-
ally, the database only included records during a 9-year
period from January 1, 2007, to December 31, 2016, so pro-
cedures (index or reoperation) that occurred outside that
time frame may have been missed. The current study
also only identified complications that occurred within 30
days of the index procedure to increase the likelihood
that the complications identified were related to the post-
operative course after meniscal repair or meniscectomy
and not another medical condition that arose. Thus, late
complications that occurred outside the 30-day window
were not captured in the present study. Cost analysis is
based on the average, per-patient total insurer payout
per diagnosis at the time of surgery and
follow-up time points. This may not be representative of
all institutions. There is also the limitation of not perform-
ing a formal chart review. Inherent to this type of study,
there are multiple unknown confounding variables, such
as no direct physical contact, patient-reported outcomes,
or medical record access to determine previous procedures,
alignment, cartilage status, meniscal tear pattern, amount
of meniscus resected, type of meniscal repair, and concom-
itant procedures.
CONCLUSION
In conclusion, meniscal repair leads to significantly lower
rates of reoperation and higher rates of early complication
with a higher total cost compared with meniscectomy in
a large database study.
REFERENCES
1. Abram SGF, Judge A, Beard DJ, Carr AJ, Price AJ. Long-term rates of
knee arthroplasty in a cohort of 834 393 patients with a history of arthro-
scopic partial meniscectomy. Bone Joint J. 2019;101(9):1071-1080.
2. Abrams GD, Frank RM, Gupta AK, Harris JD, McCormick FM, Cole
BJ. Trends in meniscus repair and meniscectomy in the United
States, 2005-2011. Am J Sports Med. 2013;41(10):2333-2339.
3. Austin PC. A comparison of 12 algorithms for matching on the pro-
pensity score. Stat Med. 2014;33(6):1057-1069.
4. Austin PC. An introduction to propensity score methods for reducing
the effects of confounding in observational studies. Multivariate
Behav Res. 2011;46(3):399-424.
5. Barnds B, Morris B, Mullen S, Schroeppel JP, Tarakemeh A, Vopat
BG. Increased rates of knee arthroplasty and cost of patients with
meniscal tears treated with arthroscopic partial meniscectomy ver-
sus non-operative management. Knee Surg Sports Traumatol
Arthrosc. 2019;27(7):2316-2321.
6. Beamer BS, Walley KC, Okajima S, et al. Changes in contact area in
meniscus horizontal cleavage tears subjected to repair and resection.
Arthroscopy. 2017;33(3):617-624.
7. Bedi A, Kelly NH, Baad M, et al. Dynamic contact mechanics of the
medial meniscus as a function of radial tear, repair, and partial menis-
cectomy. J Bone Joint Surg Am. 2010;92(6):1398-1408.
8. Bernthal NM, Seeger LL, Motamedi K, et al. Can the reparability of
meniscal tears be predicted with magnetic resonance imaging? Am
J Sports Med. 2011;39(3):506-510.
9. Brophy RH, Wojahn RD, Lillegraven O, Lamplot JD. Outcomes of
arthroscopic posterior medial meniscus root repair: association
with body mass index. J Am Acad Orthop Surg. 2019;27(3):104-111.
10. Cooper DE, Arnoczky SP, Warren RF. Meniscal repair. Clin Sports
Med. 1991;10(3):529-548.
11. Eberbach H, Zwingmann J, Hohloch L, et al. Sport-specific out-
comes after isolated meniscal repair: a systematic review. Knee
Surg Sports Traumatol Arthrosc. 2018;26(3):762-771.
12. Englund M, Guermazi A, Gale D, et al. Incidental meniscal findings on
knee MRI in middle-aged and elderly persons. N Engl J Med.
2008;359(11):1108-1115.
13. Faucett SC, Geisler BP, Chahla J, et al. Meniscus root repair vs
meniscectomy or nonoperative management to prevent knee osteo-
arthritis after medial meniscus root tears: clinical and economic
effectiveness. Am J Sports Med. 2019;47(3):762-769.
14. Feeley BT, Liu S, Garner AM, Zhang AL, Pietzsch JB. The cost-
effectiveness of meniscal repair versus partial meniscectomy: a model-
based projection for the United States. Knee. 2016;23(4):674-680.
15. Garrett WE Jr, Swiontkowski MF, Weinstein JN, et al. American
Board of Orthopaedic Surgery Practice of the Orthopaedic Surgeon:
Part-II, certification examination case mix. J Bone Joint Surg Am.
2006;88(3):660-667.
16. Goyal KS, Pan TJ, Tran D, Dumpe SC, Zhang X, Harner CD. Vertical
tears of the lateral meniscus: effects on in vitro tibiofemoral joint
mechanics. Orthop J Sports Med. 2014;2(8):2325967114541237.
17. Koh JL, Yi SJ, Ren Y, Zimmerman TA, Zhang LQ. Tibiofemoral con-
tact mechanics with horizontal cleavage tear and resection of the
medial meniscus in the human knee. J Bone Joint Surg Am.
2016;98(21):1829-1836.
18. Koh JL, Zimmerman TA, Patel S, Ren Y, Xu D, Zhang LQ. Tibiofe-
moral contact mechanics with horizontal cleavage tears and treat-
ment of the lateral meniscus in the human knee: an in vitro cadaver
study. Clin Orthop Relat Res. 2018;476(11):2262-2270.
19. Laible C, Stein DA, Kiridly DN. Meniscal repair. J Am Acad Orthop
Surg. 2013;21(4):204-213.
20. LaPrade CM, Jansson KS, Dornan G, Smith SD, Wijdicks CA,
LaPrade RF. Altered tibiofemoral contact mechanics due to lateral
meniscus posterior horn root avulsions and radial tears can be
restored with in situ pull-out suture repairs. J Bone Joint Surg Am.
2014;96(6):471-479.
21. LaPrade RF, Matheny LM, Moulton SG, James EW, Dean CS. Poste-
rior meniscal root repairs: outcomes of an anatomic transtibial pull-
out technique. Am J Sports Med. 2017;45(4):884-891.
22. Maher SA, Rodeo SA, Warren RF. The meniscus. J Am Acad Orthop
Surg. 2017;25(1):e18-e19.
23. Makris EA, Hadidi P, Athanasiou KA. The knee meniscus: structure-
function, pathophysiology, current repair techniques, and prospects
for regeneration. Biomaterials. 2011;32(30):7411-7431.
24. Moseley JB, O’Malley K, Petersen NJ, et al. A controlled trial of
arthroscopic surgery for osteoarthritis of the knee. N Engl J Med.
2002;347(2):81-88.
25. Muriuki MG, Tuason DA, Tucker BG, Harner CD. Changes in tibiofe-
moral contact mechanics following radial split and vertical tears of
the medial meniscus an in vitro investigation of the efficacy of arthro-
scopic repair. J Bone Joint Surg Am. 2011;93(12):1089-1095.
26. Ode GE, Van Thiel GS, McArthur SA, et al. Effects of serial sectioning
and repair of radial tears in the lateral meniscus. Am J Sports Med.
2012;40(8):1863-1870.
27. Paxton ES, Stock MV, Brophy RH. Meniscal repair versus partial
meniscectomy: a systematic review comparing reoperation rates
and clinical outcomes. Arthroscopy. 2011;27(9):1275-1288.
28. Petty CA, Lubowitz JH. Does arthroscopic partial meniscectomy
result in knee osteoarthritis? A systematic review with a minimum
of 8 years’ follow-up. Arthroscopy. 2011;27(3):419-424.
29. Rongen JJ, Rovers MM, van Tienen TG, Buma P, Hannink G.
Increased risk for knee replacement surgery after arthroscopic sur-
gery for degenerative meniscal tears: a multi-center longitudinal
observational study using data from the osteoarthritis initiative. Oste-
oarthritis Cartilage. 2017;25(1):23-29.
30. Roos EM, Hare KB, Nielsen SM, Christensen R, Lohmander LS. Bet-
ter outcome from arthroscopic partial meniscectomy than skin inci-
sions only? A sham-controlled randomised trial in patients aged
6Sochacki et al The American Journal of Sports Medicine
35-55 years with knee pain and an MRI-verified meniscal tear. BMJ
Open. 2018;8(2):e019461.
31. Rothermel SD, Smuin D, Dhawan A. Are outcomes after meniscal
repair age dependent? A systematic review. Arthroscopy.
2018;34(3):979-987.
32. Shanmugaraj A, Tejpal T, Ekhtiari S, et al. The repair of horizontal
cleavage tears yields higher complication rates compared to menis-
cectomy: a systematic review. Knee Surg Sports Traumatol Arthrosc.
2020;28(3):915-925.
33. Small NC. Complications in arthroscopic meniscal surgery. Clin
Sports Med. 1990;9(3):609-617.
34. Sommerfeldt MF, Magnussen RA, Randall KL, et al. The relationship
between body mass index and risk of failure following meniscus
repair. J Knee Surg. 2016;29(8):645-648.
35. Souza RB, Wu SJ, Morse LJ, Subburaj K, Allen CR, Feeley BT. Carti-
lage MRI relaxation times after arthroscopic partial medial meniscec-
tomy reveal localized degeneration. Knee Surg Sports Traumatol
Arthrosc. 2015;23(1):188-197.
36. Steadman JR, Matheny LM, Singleton SB, et al. Meniscus suture repair:
minimum 10-year outcomes in patients younger than 40 years compared
with patients 40 and older. Am J Sports Med. 2015;43(9):2222-2227.
37. Stein T, Mehling AP, Welsch F, von Eisenhart-Rothe R, Jager A.
Long-term outcome after arthroscopic meniscal repair versus arthro-
scopic partial meniscectomy for traumatic meniscal tears. Am J
Sports Med. 2010;38(8):1542-1548.
38. Thorlund JB, Holsgaard-Larsen A, Creaby MW, et al. Changes in
knee joint load indices from before to 12 months after arthroscopic
partial meniscectomy: a prospective cohort study. Osteoarthritis Car-
tilage. 2016;24(7):1153-1159.
39. Waugh N, Mistry H, Metcalfe A,et al. Meniscal allograft transplantation
after meniscectomy: clinical effectiveness and cost-effectiveness.
Knee Surg Sports Traumatol Arthrosc. 2019;27(6):1825-1839.
40. Xu C, Zhao J. A meta-analysis comparing meniscal repair with
meniscectomy in the treatment of meniscal tears: the more menis-
cus, the better outcome? Knee Surg Sports Traumatol Arthrosc.
2015;23(1):164-170.
For reprints and permission queries, please visit SAGE’s Web site at http://www.sagepub.com/journalsPermissions.nav.
AJSM Vol. XX, No. X, XXXX Meniscectomy Has Higher Reoperation Rate Than Repair 7
... On the other hand, meniscus repair is more suitable for younger patients (age < 40) with peripheral reducible tears (e.g., nearer the capsular attachment) of the horizontal or longitudinal pattern and shows 80% success at two years [5,6]. However, symptomatic tears not amenable to repair should be treated with meniscectomy, as meniscus function can still be preserved, especially when the peripheral meniscus rim is intact [5,7]. ...
... The general characteristics of the included studies are presented in Table 1. A total of 16 studies were identified and included; six performed PEEs [7,[14][15][16][17][18], seven CUAs [6,[19][20][21][22][23][24], two CEA [25,26], and one study performed a CUA, CEA, and CBA simultaneously [12]. Five studies compared meniscus repair vs meniscectomy [6,7,19,20,22], three studies compared costs of meniscectomy vs non-operative treatment [14,17,24], two studies compared physical therapy with delayed meniscectomy vs early meniscectomy [12,21], two studies directly compared the costs of having vs not having physical therapy after a meniscectomy [15,16], three studies investigated meniscus transplantation, and one study compared costs associated with conventional arthroscopic instruments vs laser-assisted treatment in meniscectomy [18]. ...
... A total of 16 studies were identified and included; six performed PEEs [7,[14][15][16][17][18], seven CUAs [6,[19][20][21][22][23][24], two CEA [25,26], and one study performed a CUA, CEA, and CBA simultaneously [12]. Five studies compared meniscus repair vs meniscectomy [6,7,19,20,22], three studies compared costs of meniscectomy vs non-operative treatment [14,17,24], two studies compared physical therapy with delayed meniscectomy vs early meniscectomy [12,21], two studies directly compared the costs of having vs not having physical therapy after a meniscectomy [15,16], three studies investigated meniscus transplantation, and one study compared costs associated with conventional arthroscopic instruments vs laser-assisted treatment in meniscectomy [18]. ...
Article
Full-text available
Purpose To evaluate the overall evidence of published health-economic evaluation studies on meniscus tear treatment. Methods Our systematic review focuses on health-economic evaluation studies of meniscus tear treatment interventions found in PubMed and Embase databases. A qualitative, descriptive approach was used to analyze the studies’ results and systematically report them following PRISMA guidelines. The health-economic evaluation method for each included study was categorized following one of the four approaches: partial economic evaluation (PEE), cost-effectiveness analysis (CEA), cost–benefit analysis (CBA), or cost-utility analysis (CUA). The quality of each included study was assessed using the Consensus on Health Economic Criteria (CHEC) list. Comparisons of input variables and outcomes were made, if applicable. Results Sixteen studies were included; of these, six studies performed PEE, seven studies CUA, two studies CEA, and one study combined CBA, CUA, and CEA. The following economic comparisons were analyzed and showed the respective comparative outcomes: (1) meniscus repair was more cost-effective than arthroscopic partial meniscectomy (meniscectomy) for reparable meniscus tear; (2) non-operative treatment or physical therapy was less costly than meniscectomy for degenerative meniscus tear; (3) physical therapy with delayed meniscectomy was more cost-effective than early meniscectomy for meniscus tear with knee osteoarthritis; (4) meniscectomy without physical therapy was less costly than meniscectomy with physical therapy; (5) meniscectomy was more cost-effective than either meniscus allograft transplantation or meniscus scaffold procedure; (6) the conventional arthroscopic instrument cost was lower than laser-assisted arthroscopy in meniscectomy procedures. Conclusion Results from this review suggest that meniscus repair is the most cost-effective intervention for reparable meniscus tears. Physical therapy followed by delayed meniscectomy is the most cost-effective intervention for degenerative meniscus tears. Meniscus scaffold should be avoided, especially when implemented on a large scale. Level of evidence Systematic review of level IV studies.
... 80 A retrospective analysis of 22,064 patients with partial meniscectomies and 5516 meniscus repairs demonstrated a higher reoperation rate and progression to total knee replacement in the partial meniscectomy patients. 81 The meniscus repair group had a higher immediate postoperative complication rate (1.2% vs. 0.88%) and day of surgery costs ($7094 vs. $5423). 81 Another analysis of meniscus repair versus debridement showed improved long term outcomes, cost-savings and fewer patients going on to total knee replacement in the meniscus repair group. ...
... 81 The meniscus repair group had a higher immediate postoperative complication rate (1.2% vs. 0.88%) and day of surgery costs ($7094 vs. $5423). 81 Another analysis of meniscus repair versus debridement showed improved long term outcomes, cost-savings and fewer patients going on to total knee replacement in the meniscus repair group. 78 Meniscus repair at the time of ACL reconstruction has been shown to be more costeffective than meniscus debridement at the time of ACL reconstruction. ...
Article
Meniscus surgery is one of the most commonly performed orthopedic procedures worldwide. Modifiable risk factors for meniscus injury include body mass index, participation in athletics and occupation. Nonmodifiable risk factors include age, sex, lower extremity alignment, discoid meniscus, ligamentous laxity, and biconcave tibial plateau. Conditions commonly associated with meniscal injury are osteoarthritis, anterior cruciate ligament injury, and tibial plateau fractures. Tear type and location vary by patient age and functional status. Surgical management of meniscus injury is typically cost-effective in terms of quality-adjusted life years. The purpose of this review is to provide an overview of meniscal injury epidemiology by summarizing tear types and locations, associated conditions, and factors that increase the risk for meniscal injury. The economic burden of meniscus injury and strategies to prevent injury to the meniscus are also reviewed.
... 5,19 This discrepancy is likely caused by the use of additional meniscal repair implants, increased operating time, and accordingly additional anesthetics use. 6,20,21 Determination of the substantial costs is necessary for the healthcare system to properly facilitate accessible medical care. We therefore propose a new national price for ACLR procedures and adjustment of ACLR costs with concomitant meniscal procedure. ...
Article
Full-text available
Objective: The number of anterior cruciate ligament reconstruction (ACLR) procedures is increasing. However, ACLR procedures are likely to be underbudgeted in a developing country like Indonesia. This study aimed to analyze costs for ACLR procedures in Indonesia's resource-limited context, determine the burden of ACLR, and suggest national prices for ACLR reimbursement. Methods: A retrospective observational study was conducted between 1 January and 31 December 2019 on the cost of ACLR from a payer perspective using inpatient billing records in four hospitals. The national burden of ACLR was calculated, and projected national prices for reimbursement were determined. Results: Of 80 ACLRs, 53 (66%) were isolated ACLRs and 27 (34%) ACLRs were combined with meniscus treatment. Mean hospital costs incurred per ACLR procedure were US$ 2853, with the dominant cost relating to orthopedic implant prices (US$ 1,387.80). The costs of ACLR with combined meniscus treatment were estimated as being 35% higher than isolated ACLR. The national burden of ACLR showed a total budget of US$ 367.4 million per 100,000 patients (0.03% of GDP) for ACLR with additional meniscus treatment and US$ 271.3 million per 100,000 patients (0.02% of GDP) for isolated ACLR. Conclusion: ACLR procedures in Indonesia are likely underbudgeted. Adjustments of reimbursement prices for ACLR are needed to facilitate adequate access of Indonesians to the procedures. This study demonstrated varying costs determined for ACLR in Indonesia, which entails that a new reimbursement system with improvement of national prices should become the core of transformation.
... In an effort to avoid a potential second operation, meniscectomy has led to reliable return to play [51,62]. With growing evidence of the potential short-and long-term negative effects of meniscectomy [8,17,62], especially of the lateral meniscus, treatment is currently evolving to include more meniscal repairs [1,11,82]. ...
Article
Full-text available
Meniscal injuries in elite athletes are a common cause of missed game time and even have the potential to be career shortening. In this patient group, care must be paid not only to the pathology, but also to a player’s contract status, time in the season, specific demands of his/her sport and position on the field, and future consequences. Successful treatment requires the clinician to understand the player’s goals and needs, communicate effectively between all stakeholders, and a have knowledge of the challenges posed by the different types of meniscal tear seen in this population. Paramount is the distinction between injuries to the medial and lateral meniscus. Deficiency of the lateral meniscus, as a result of a tear or a meniscectomy, leads to frequent early problems and inexorably to chondral degeneration thereby affecting an athlete’s ability to perform. Therefore, it is strongly recommended to repair the majority of lateral meniscal tears. Medial meniscal tears pose a more challenging treatment dilemma, as the success of partial meniscectomy in achieving reproducible, early return to play must be balanced against the long-term degenerative consequences. Many meniscal tears are correctly treated non-operatively.Level of evidence V.
Article
PurposeOrthopedic literature remains divided on the utility of biologic augmentation to optimize outcomes after isolated meniscal repair. The aim of this systematic review is to analyze the clinical outcomes and re-operation rates of biologically augmented meniscal repairs.Methods PubMed, CINAHL, Cochrane, and EMBASE databases were queried in October 2020 for published literature on isolated meniscal repair with biological augmentation. Studies were assessed for quality and risk of bias by two appraisal tools. Patient demographics, meniscal tear characteristics, surgical procedure, augmentation type, post-operative rehabilitation, patient reported outcome measures, and length of follow-up were recorded, reviewed, and analyzed by two independent reviewers.ResultsOf 3794 articles, 18 met inclusion criteria and yielded 537 patients who underwent biologic augmentation of meniscal repair. The biologically augmented repair rates were 5.8–27.0% with PRP augmentation, 0.0–28.5% with fibrin clot augmentation, 0.0–12.9% with marrow stimulation, and 0.0% with stem cell augmentation. One of seven studies showed lower revision rates with augmented meniscal repair compared to standard repair techniques, whereas five of seven found no benefit. Three of ten studies found significant functional improvement of biologically augmented repair versus standard repair techniques and six of ten studies found no difference. There was significant heterogeneity in methods for biologic preparation, delivery, and post-operative rehabilitation protocols.Conclusion Patients reported significant improvements in functional outcomes scores after repair with biological augmentation, though the benefit over standard repair controls is questionable. Revision rates after biologically augmented meniscal repair also appear similar to standard repair techniques. Clinicians should bear this in mind when considering biologic augmentation in the setting of meniscal repair.Level of evidenceIV.
Article
Full-text available
Zusammenfassung Hintergrund Durch das Reformgesetz des Medizinischen Dienstes der Kassen (MDK) soll u. a. eine Verlagerung bislang stationär erbrachter Leistungen in den ambulanten Versorgungsektor bzw. die Versorgung nach §115b SGB V umgesetzt werden. Ziel dieser Arbeit ist die Untersuchung bestimmter Gruppen stationärer Fälle eines universitären Maximalversorgers für Unfallchirurgie und Orthopädie, die das Risiko einer operativen Ambulantisierung tragen. Methodik Die Datenerfassung mittels SAP Data Warehouse umfasst alle stationären Fälle 2017–2019. Es erfolgt die Subgruppenanalyse der Krankenhausleistungsparameter von 3 potenziellen Risikogruppen (RG): 1) primäre Fehlbelegungen, 2) Katalogleistungen der AOP-Kategorie 1 und/oder 2 sowie 3) elektive Eintagesfälle als hypothetische Risikogruppe. Zudem erfolgt eine Analyse epidemiologischer und ökonomischer Parameter. Ergebnisse Eine primäre Fehlbelegung (RG 1) wurde vom MDK in 245 Fällen beanstandet. RG 2 umfasst 764 Fälle und RG 3 891 Fälle. Das Kollektiv wies ein Durchschnittsalter von 45,5 ± 17,7 Jahren auf und zeigte in 90 % keine relevanten Nebendiagnosen (PCCL 0). Der Hauptanteil der Fälle ließ sich den DRG I23B und I21Z (Entfernung von Osteosynthesematerial, 15–23 %) zuordnen, nachfolgend offenen oder arthroskopischen Eingriffen an den Extremitäten (DRG I32F, I32G, I24Z, I18B, 6–9 %). Im Falle einer zunehmenden Ambulantisierung ergibt sich ein potenzielles Erlösrisiko 2017 von 1.049.207 €, 2018 von 1.076.727 € und 2019 von 923.163 €. Schlussfolgerung Einzelne Gruppen haben ein erhöhtes Transferpotenzial in bestimmten DRG für ambulante Operationen. Eine proaktive Patientensteuerung in Bezug auf ambulante vs. stationäre Behandlung sowie ein besonderes Management personeller und räumlicher Ressourcen sind notwendig, um nachgelagerte Erlöskürzungen zu antizipieren.
Article
Purpose The purpose of this review is to perform a meta-analysis of studies reporting meniscus repair outcomes. Pooled analyses of such studies will provide an accurate estimate of the outcomes that can be expected following meniscal repair at various postoperative timepoints. Methods A meta-analysis of meniscal repair failure (defined as persistent symptoms, lack of healing on MRI or revision surgery) and other clinical outcomes was performed following meniscal repair. Patient included had traumatic, non-degenerative meniscal tears, were skeletally mature, and had specific time-points after surgery. Repairs included were performed either in isolation, or with concomitant ACL reconstruction. Due to the inherent heterogeneity of single-arm meta-analyses, pooled analyses were performed utilizing a random-effects model. Results Rates of all-cause meniscal repair failure was pooled to be 12% at 0-1 years (95% CI: 0.09-0.16), 15% at 2-3 years (95% CI: 0.11-0.20), and 19% at 4-6 years (95% CI: 0.13-0.24). Sensitivity analysis for studies performing meniscal repair entirely on patients with concomitant ACL reconstruction (ACLR) showed comparable rates of failure at similar time intervals. Development of osteoarthritis (OA), in patients with knees previously free from articular pathologies, was 4% at 2-3 years (95% CI: 0.02-0.07), and 10% at 4-6 years (95% CI: 0.03-0.25). Conclusion Meniscus repair for traumatic injuries have an all-cause failure rate that increases from 12% to 19% through a time period raging from one to six years following surgery. The failure rates were comparable for patients with meniscal repairs performed with concomitant ACLRs.
Article
Full-text available
Purpose Horizontal cleavage tears of the meniscus (HCTs) are primarily degenerative in nature, and, however, can be the result of trauma. Such tears account for 12–35% of all tear patterns and can be treated by partial meniscectomy or arthroscopic repair. The purpose of this review was to systematically assess the outcomes and complications for patients undergoing the surgical treatment of HCTs. Methods This review has been conducted according to the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-analyses. The electronic databases PubMed, MEDLINE, and EMBASE were searched from data inception to December 30, 2018 for articles addressing the surgical treatment of HCTs. The Methodological Index for Non-randomized Studies was used to assess study quality. Data are presented descriptively. Results Overall, 23 studies were identified, comprising of 702 patients (708 knees) with a mean age of 36.6 ± 9.9 years and a mean follow-up of 33.6 ± 19.6 months. The majority of patients were treated with a partial meniscectomy (59.0%), followed by repair (32.8%) and total meniscectomy (8.2%). Both meniscectomy and repair patients had improvements which surpassed minimal clinically important differences with regard to clinical (e.g. pain, function, daily living) and radiographic outcomes. The overall complication rate was 5.1%, primarily involving patients undergoing meniscal repair (12.9% of all knees undergoing a repair). Conclusion Although meniscal repair theoretically may provide improvement in biomechanical loading, patients undergoing repair had higher complication rates than those undergoing partial meniscectomy. Clinicians should consider the available implants in determining which tear patterns to repair and future studies with long-term follow-up are needed to investigate complications (e.g. secondary meniscal procedures) as well as the potential for delay in the development of osteoarthritis. Level of evidence Level IV.
Article
Full-text available
Purpose To assess the clinical effectiveness and cost-effectiveness of meniscal allograft transplantation (MAT) after meniscal injury and subsequent meniscectomy. Methods Systematic review of clinical effectiveness and cost-effectiveness analysis. Results There is considerable evidence from observational studies, of improvement in symptoms after meniscal allograft transplantation, but we found only one small pilot trial with a randomised comparison with a control group that received non-surgical care. MAT has not yet been proven to be chondroprotective. Cost-effectiveness analysis is not possible due to a lack of data on the effectiveness of MAT compared to non-surgical care. Conclusion The benefits of MAT include symptomatic relief and restoration of at least some previous activities, which will be reflected in utility values and hence in quality-adjusted life years, and in the longer term, prevention or delay of osteoarthritis, and avoidance or postponement of some knee replacements, with resulting savings. It is likely to be cost-effective, but this cannot be proven on the basis of present evidence. Level of evidence IV.
Article
Full-text available
Background: Medial meniscus root tears are a common knee injury and can lead to accelerated osteoarthritis, which might ultimately result in a total knee replacement. Purpose: To compare meniscus repair, meniscectomy, and nonoperative treatment approaches among middle-aged patients in terms of osteoarthritis development, total knee replacement rates (clinical effectiveness), and cost-effectiveness. Study Design: Meta-analysis and cost-effectiveness analysis. Methods: A systematic literature search was conducted. Progression to osteoarthritis was pooled and meta-analyzed. A Markov model projected strategy-specific costs and disutilities in a cohort of 55-year-old patients presenting with a meniscus root tear without osteoarthritis at baseline. Failure rates of repair and meniscectomy procedures and disutilities associated with osteoarthritis, total knee replacement, and revision total knee replacement were accounted for. Utilities, costs, and event rates were based on literature and public databases. Analyses considered a time frame between 5 years and lifetime and explored the effects of parameter uncertainty. Results: Over 10 years, meniscus repair, meniscectomy, and nonoperative treatment led to 53.0%, 99.3%, and 95.1% rates of osteoarthritis and 33.5%, 51.5%, and 45.5% rates of total knee replacement, respectively. Meta-analysis confirmed lower osteoarthritis and total knee replacement rates for meniscus repair versus meniscectomy and nonoperative treatment. Discounted 10-year costs were $22,590 for meniscus repair, as opposed to $31,528 and $25,006 for meniscectomy and nonoperative treatment, respectively; projected quality-adjusted life years were 6.892, 6.533, and 6.693, respectively, yielding meniscus repair to be an economically dominant strategy. Repair was either cost-effective or dominant when compared with meniscectomy and nonoperative treatment across a broad range of assumptions starting from 5 years after surgery. Conclusion: Repair of medial meniscus root tears, as compared with total meniscectomy and nonsurgical treatment, leads to less osteoarthritis and is a cost-saving intervention. While small confirmatory randomized clinical head-to-head trials are warranted, the presented evidence seems to point relatively clearly toward adopting meniscus repair as the preferred initial intervention for medial meniscus root tears.
Article
Full-text available
Objective Compare arthroscopic partial meniscectomy to a true sham intervention. Methods Sham-controlled superiority trial performed in three county hospitals in Denmark comparing arthroscopic partial meniscectomy to skin incisions only in patients aged 35–55 years with persistent knee pain and an MRI-confirmed medial meniscus lesion. A computer-generated table of random numbers generated two comparison groups. Participants and outcome assessors were blinded to group allocation. Exclusions were locking knees, high-energy trauma or severe osteoarthritis. Outcomes were collected at baseline, 3 and 24 months. We hypothesised no difference between groups. The primary outcome was the between-group difference in change from baseline to 2 years in the mean score across all five normalised Knee injury and Osteoarthritis Outcome Score (KOOS) subscales (KOOS5). Results Forty-four patients (of the estimated 72) underwent randomisation; 22 in each group. Sixteen participants (36%) were non-blinded and eight participants (36%) from the sham group crossed over to the surgery group prior to the 2-year follow-up. At 2 years, both groups reported clinically relevant improvements (surgery 21.8, skin incisions only 13.6), the mean difference between groups was 8.2 in favour of surgery, which is slightly less than the cut-off of 10 prespecified to represent a clinically relevant difference; judged by the 95% CI (−3.4 to 19.8), a possibility of clinically relevant difference could not be excluded. In total, nine participants experienced 11 adverse events; six in the surgery group and three in the skin-incisions-only group. Conclusion We found greater improvement from arthroscopic partial meniscectomy compared with skin incisions only at 2 years, with the statistical uncertainty of the between-group difference including what could be considered clinically relevant. Because of the study being underpowered, nearly half in the sham group being non-blinded and one-third crossing over to surgery, the results cannot be generalised to the greater patient population. Trial registration number NCT01264991.
Article
Full-text available
PurposeThe purpose of this systematic review was to assess sport-specific outcomes after repair of isolated meniscal tears. MethodsA systematic electronic search of the MEDLINE and Cochrane database was performed in May 2016 to identify studies that reported sport-specific outcomes after isolated meniscal repair. Included studies were abstracted regarding study characteristics, patient demographics, surgical technique, rehabilitation, and outcome measures. The methodological quality of the included studies was assessed with the Coleman Methodology Score (CMS). ResultsTwenty-eight studies with a total of 664 patients met the inclusion criteria. The methodological quality of the included studies was moderate, with a mean CMS of 69.7 ± 8.3. The mean patient age was 26 ± 7.2 years and 71% of patients were male. Mean preoperative Tegner score improved from 3.5 ± 0.3 to 6.2 ± 0.8 postoperatively. Comparing preinjury and postoperative Tegner scores, comparable values were observed (6.3 ± 1.1 and 5.7 ± 0.8, respectively). Return to sports on the preinjury level was achieved in 89%. Mixed-level populations returned to their preinjury activity level in 90% and professional athletes in 86%. Mean delay of return to sports varied between 4.3 and 6.5 months, with comparable results between professional and mixed-level athletes. The pooled failure rate was 21%. The failure rate was lower in professional athletes compared to mixed-level athletes (9% vs. 22%). Conclusion This systematic review suggests that isolated repair of meniscal tears results in good to excellent sport-specific outcomes and a high return to sports rate in both recreational and professional athletes. The failure rate is comparable to systematic reviews not focusing on sportive patients. Level of evidenceLevel IV systematic review of Level I to Level IV studies.
Article
Aims The aim of this study was to determine the long-term risk of undergoing knee arthroplasty in a cohort of patients with meniscal tears who had undergone arthroscopic partial meniscectomy (APM). Patients and Methods A retrospective national cohort of patients with a history of isolated APM was identified over a 20-year period. Patients with prior surgery to the same knee were excluded. The primary outcome was knee arthroplasty. Hazard ratios (HRs) were adjusted by patient age, sex, year of APM, Charlson comorbidity index, regional deprivation, rurality, and ethnicity. Risk of arthroplasty in the index knee was compared with the patient’s contralateral knee (with vs without a history of APM). A total of 834 393 patients were included (mean age 50 years; 37% female). Results Of those with at least 15 years of follow-up, 13.49% (16 256/120 493; 95% confidence interval (CI) 13.30 to 13.69) underwent subsequent arthroplasty within this time. In women, 22.07% (95% CI 21.64 to 22.51) underwent arthroplasty within 15 years compared with 9.91% of men (95% CI 9.71 to 10.12), corresponding to a risk ratio (RR) of 2.23 (95% CI 2.16 to 2.29). Relative to the general population, patients with a history of APM were over ten times more likely (RR 10.27; 95% CI 10.07 to 10.47) to undergo arthroplasty rising to almost 40 times more likely (RR 39.62; 95% CI 27.68 to 56.70) at a younger age (30 to 39 years). In patients with a history of APM in only one knee, the risk of arthroplasty in that knee was greatly elevated in comparison with the contralateral knee (no APM; HR 2.99; 95% CI 2.95 to 3.02). Conclusion Patients developing a meniscal tear undergoing APM are at greater risk of knee arthroplasty than the general population. This risk is three-times greater in the patient’s affected knee than in the contralateral knee. Women in the cohort were at double the risk of progressing to knee arthroplasty compared with men. These important new reference data will inform shared decision making and enhance approaches to treatment, prevention, and clinical surveillance. Cite this article: Bone Joint J 2019;101-B:1071–1080.
Article
Purpose The purpose of this study was to determine the cost of arthroscopic partial meniscectomy (APM), one of the most common surgeries performed by orthopaedic surgeons, and the associated rate of progression to knee arthroplasty (KA) compared to patients treated non-operatively after diagnosis of meniscal tear. Methods Utilizing data mining software (PearlDiver, Colorado Springs, CO), a national insurance database of approximately 23.5 million orthopaedic patients was queried for patients diagnosed with a meniscal tear. Patients were classified by treatment: non-operative and arthroscopic partial meniscectomy and were followed after initial diagnosis for cost and progression to knee arthroplasty. Results There were 176,407 subjects in the non-op group and 114,194 subjects in the arthroscopic partial meniscectomy group. Arthroscopic partial meniscectomy generated more cost than non-operative ($3842.57 versus $411.05, P < 0.001). Arthroscopic partial meniscectomy demonstrated greater propensity to need future knee arthroplasty (11.4% at 676 days) than those treated non-operatively (9.5% at 402 days) (P < 0.001). Female patients demonstrated a higher rate of progression to knee arthroplasty in the arthroscopic partial meniscectomy and non-operative groups (P < 0.001). Conclusion Compared to non-operative treatment for meniscal tears, arthroscopic partial meniscectomy is more expensive and does not appear to decrease the rate of progression to knee arthroplasty. Patients undergoing arthroscopic partial meniscectomy yielded on average a delay of only 9 months (274 days) before undergoing knee arthroplasty. Female patients experienced a significantly higher rate of progression to knee arthroplasty. The authors recognize the limitations of this type of study including its retrospective nature, reliance upon accurate coding and billing information, and the inability to determine whether symptoms including mechanical locking played a role in the decision to perform an APM. Level of evidence IV.
Article
Introduction: The purpose of this study was to assess the association of outcomes from posterior medial meniscus root repairs with patient age, sex, and body mass index (BMI). Methods: Patients who underwent arthroscopic posterior medial meniscus root repair completed the Knee Injury and Osteoarthritis Outcome Score (KOOS) and reported subsequent surgeries. The association of patient factors with subsequent surgery and clinical osteoarthritis (OA) based on the KOOS score was evaluated. Results: Minimum 2-year follow-up was available on 22/25 patients (88%). Two patients (9.1%) had subsequent surgeries, and 10 (45.5%) met the KOOS criteria for OA. A BMI over 35 kg/m was associated with repeat surgery (25% versus 0%; P = 0.049) and clinical OA (75% versus 28.6%; P = 0.035). Conclusion: Although arthroscopic repair of posterior medial root tears has good clinical outcomes and a low rate of subsequent surgery, an elevated BMI level is associated with worse clinical outcomes and a higher rate of subsequent surgery.
Article
Background: Partial meniscectomy is one of the most commonly performed orthopaedic procedures for a meniscus tear. Decreased contact area and increased contact pressure have been seen in partial meniscectomies from treatment of various types of meniscal tears; however, the biomechanical effect of a horizontal cleavage tear in the lateral meniscus and subsequent treatment are unknown. Questions/purposes: This study asked whether a horizontal cleavage tear of the lateral meniscus, resecting the inferior leaf, and further resecting the superior leaf would (1) decrease contact area and (2) increase peak contact pressure. Methods: Eleven fresh-frozen human cadaveric knees were evaluated under five conditions of intact meniscus, horizontal cleavage tear, inferior leaf resection, and resection of the inferior and superior leaves of the lateral meniscus. Tibiofemoral contact area and pressure were measured at 0° and 60° knee flexion under an 800-N load, normalized to that at the intact condition of the corresponding knee flexion, and compared across the five previously described conditions. Results: At 0° knee flexion, normalized contact area with inferior leaf resection (65.4% ± 14.1%) was smaller than that at the intact condition (100% ± 0.0%, p < 0.001); smaller than horizontal cleavage tear (94.1% ± 5.8%, p = 0.001) contact area; and smaller than repaired horizontal tear (92.8% ± 8.2%, p = 0.001) contact area. Normalized contact area with further superior leaf resection (50.5% ± 7.3%) was smaller than that at the intact condition (100% ± 0.0%, p < 0.001); smaller than horizontal cleavage tear (94.1% ± 5.8%, p < 0.001) contact area; and smaller than repaired horizontal tear (92.8% ± 8.2%, p < 0.001) contact area. At 60° flexion, normalized contact area with inferior leaf resection (76.1% ± 14.8%) was smaller than that at the intact condition (100% ± 0.0%, p = 0.004); smaller than horizontal cleavage tear (101.8% ± 7.2%, p = 0.006) contact area; and smaller than repaired horizontal tear (104.0% ± 13.3%, p < 0.001) contact area. Normalized contact area with further superior leaf resection (52.1% ± 16.7%) was smaller than that at the intact condition (100% ± 0.0%, p < 0.001); smaller than horizontal cleavage tear (101.8% ± 7.2%, p < 0.001) contact area; and smaller than repaired horizontal tear (104.0% ± 13.3%, p < 0.001) contact area. At 60° flexion, contact area with both leaf resection (52.1% ± 16.7%) was smaller than that with inferior leaf resection (76.1% ± 14.8%, p = 0.039). At 0° knee flexion, peak pressure increased to 127.0% ± 22.1% with inferior leaf resection (p = 0.026) and to 138.6% ± 24.3% with further superior leaf resection (p = 0.002) compared with that at the intact condition (100% ± 0.0%). At 60° flexion, compared with that at the intact condition (100% ± 0.0%), peak pressure increased to 139% ± 33.6% with inferior leaf resection (p = 0.035) and to 155.5% ± 34.7% (p = 0.004) with further superior leaf resection. Conclusions: Resection of the inferior leaf or both leaves of the lateral meniscus after a horizontal cleavage tear resulted in decreased contact area and increased peak contact pressure at 0° and 60° knee flexion. Clinical relevance: In vitro resection of one or both leaves of a horizontal cleavage tear of the lateral meniscus causes increases in peak pressure, consistent with other types of partial meniscectomies associated in a clinical setting with excessive loading and damage to knee cartilage. Clinical outcomes in patients undergoing partial leaf meniscectomy could confirm this theory. Avoidance of resection may be relatively beneficial for long-term function. The findings of this in vitro study lend biomechanical support for nonoperative management.
Article
Purpose: To determine if the failure rate and functional outcome after arthroscopic meniscus suture repair are age dependent. Methods: A systematic review was conducted using a computerized search of the electronic databases MEDLINE and ScienceDirect in adherence with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Extracted data from each included study were recorded on a standardized form. Studies were included if they (1) were English-language studies in peer-reviewed journals, (2) used a distinct age cut-off to evaluate outcome of meniscal surgery for those above and below the specified cut-off, and (3) used meniscal repairs using suture based technique with inside-out, outside-in, or all-inside techniques. Review papers, case reports, technique papers, non-English language publications, abstracts, and data on meniscal repairs using meniscal screws, arrows, or darts were excluded. Results: 15 of 305 identified articles met the inclusion/exclusion criteria. There were 1,141 menisci treated in 1,063 patients. Seven and 8 studies met the inclusion/exclusion criteria for analysis for the age thresholds of 25 years and 30 years, respectively, demonstrating no difference in failure rates relative to age threshold. Four of 6 studies that met analysis criteria found no difference in failure rates above or below an age threshold of 35 years. No significant difference in failure in patients younger than 40 than patients older than 40 was found for 4 of the 5 studies in that arm of the review. Conclusions: Analysis of the composite data in this systematic review reveals that no significant difference exists when evaluating meniscal repair failure rate as a function of age above or below the given age thresholds. Level of evidence: Level IV, systematic review of level III and IV studies.