Based on the 3-layer framework of Enterprise Resource Planning (ERP), Manufacturing Execution System (MES), and Process Control System (PCS), application of simulation technology in petrochemical enterprises was reviewed. Furthermore, the importance of integrated simulation system for process industry to the production processes and the business operations in modern enterprises was emphasized,
... [Show full abstract] and key problems of integrated simulation technologies were pointed out. These key problems included multi-resolution modeling, standards of the distributed integrated simulation technology, architecture of the distributed integrated simulation system and visualized simulation. Finally, prospect of future simulation research was also introduced.