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Assessment Of Antagonistic Effect Of Alcoholic Extract From Cyanophyta (Spirulina platensis) Against Several Human and Plant Derived Pathogenic Fungi
... Furthermore, Al-Ghanayem (2017) stated that the antifungal activity of the alga occurs because of the presence of its intracellular and extracellular metabolites. Fayyad et al. (2020) presented that S. platensis extract exhibited inhibitory activity towards Candida albicans, C. glurbrate, C. fameta, C. lustrans, Aspergillus niger, A. flavus, Mucor sp., and Botrytis sp. Bencheikh et al. (2022) recently enhanced the production S. platensis, investigating its ability to produce antifungal compounds against Fusarium culmorum, Alternaria solani, and Cladosporium sp. ...
Spirulina platensis has roles in biotechnological product advancement due to its safety for humans and animals. Analysis of S. platensis extract by high-performance liquid chromatography reflected the presence of 14 phenolic and flavonoid compounds with different concentrations such as ellagic acid (333 µg/g), gallic acid (294 µg/g), methyl gallate (147 µg/g), naringenin (144 µg/g), and chlorogenic acid (142 µg/g). The isolated Aspergillus flavus from silage of maize was tested to evaluate the effect of S. platensis extract on aflatoxins B1, B2, G1, and G2 production. The treated silage with S. platensis extract showed the presence of 37±0.33 ppb, 0.59±0.16 ppb, 0.26±0.22 ppb, and 0.21±0.18 ppb compared to untreated silage that showed 3.14±0.15 ppb, 0.81±0.08 ppb, 0.46±0.05 ppb, and 0.26±0.23 ppb aflatoxins of B1, B2, G1, and G2. These results were shown on the 10 th day of incubation. On the 15 th day of incubation, the treated silage showed less mycotoxins than untreated silage. At different incubation periods, glucosamine was estimated as a growth development biomarker. The content of glucosamine was inhibited as a result of the effect of S. platensis extract on fungus growth with 53.71%, 49.19%, 47.84%, 38.47%, and 35.72% inhibition on the 3 rd , 6 th , 9 th , 12 th , and 15 th day.
... 4. Cyclopropanebutanoic acid authenticated as antifungal agent 15 . 5. Eicosanoic acid is fatty acid reported as antimicrobial activity 16 . Antibiotic sensitivity Assay: Antimicrobial resistance has become an intensive problem, since synthetic drugs agents like antibiotics have shown a potency toward many infectious diseases , their use most be limited due to the fast incidence of resistant development by pathogens. ...
Plant-derived medications remain an attractive resource to fight many diseases especially in developing countries, Morenga oleifera is called (miracle tree) due to its potential use in many diseases treatment traditionally. After cultivation of Morenga locally, alcoholic leaves extract has prepared by maceration. Authors intended to provide a phytochemical profiling for leaves of Morenga via GC-Mass analysis. Then directed fifteen bioactive compounds that investigated within alcoholic leaves extract to explore their ability to inhibit the growth of several tested pathogens and to inhibit proliferation of breast cancer cell line by using MTT assay. Authors hypothesized that plant extract was good candidate as safe and alternative therapy against infections caused by Pseudomonas aurogenosa, Streptococcus sp. and Candiad albicans after calculating (22± 0.002, 20± 0.002, 23± 0.003)mm. Inhibition zones by plant extract against the previous pathogens respectively as compared with synthetic antibiotics. The decrease of absorbance values were detected when treat MCF7 cell line with different concentration of plant extract as compare with un treated cancer cells after follow-up periods especially after 48 hr. incubation. This indicates that Morenga leaves could be a potential drug to eliminate breast cancer incidences.
This review summarises the available evidence on the prospects for using microalgae or their extracts to support crop production. The evidence is limited but suggests technological promise in several distinct ways, namely, higher core productivity, enhanced resilience to biotic and abiotic stresses, and better-quality produce. The different efficacy pathways of these microalgal technologies were examined to assess their scope to help address key farmer priorities. Their scope to help farmers face climate change and land degradation was a particular focus, given the magnitude of these threats. These microalgal technologies are framed in terms of their pertinence to farmer priorities due to the centrality of farmers to food systems. Notably, farmers' technology adoption decisions are key to food system outcomes. The findings reported suggest that these crop support technologies could potentially deliver major benefits to farmers, consumers, and the environment. For the moment, however, this emerging literature remains largely neglected. Possible reasons for this are considered, as are potential ways forward. The review focuses particularly on the two most researched and widely available microalgae, the genera Arthrospira and Chlorella, in the interest of highlighting options farmers could adopt rapidly while research on the wider body of microalgae-based crop technologies continues.
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