This communication deals with model calibration, i.e. the parameter estimation of large and complex simulation models, from imposed experimental data. A calibra-tion methodology including practical identifiability, parameter selection and parameter estimation is proposed. The estimation of the sensitivity functions of the model outputs is performed by a new software : Diffedge® that enables us to ... [Show full abstract] symbolically derive a mathematical model described by a block diagram implemented in Simulink®. A case study of a winding system is detailed to illustrate the ‘applicability’ of such an approach in practice.