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Review on Hair Problem and its Solution

  • Zim laboratories pvt limited, Nagpur
  • R. J. World College of Pharmacy Education and Technology


Hair is simple in structure. Hair is formed of an extreme protein called Keratin. Cleanser may be a hair care item, ordinarily as a gooey fluid, that's utilized for cleaning hair. the problems related with it incorporates male pattern baldness, raucous hair, absence of hair volume, molding, youthful turning gray, dandruff, diminishing of hair, bluntness then on. Male pattern baldness are often caused due to various reasons, for instance , hereditary propensities, ecological triggers and presentation to synthetic compounds, medications, healthful inadequacy, outrageous pressure or long ailment then on. Gentle dandruff can for the foremost part be settled by washing the hair a day with a mellow cleanser hair. Sedated hostile to dandruff cleanser clean both the hair and scalp and leave the hair reasonable, not bother sebaceous organs. It contains an enemy of microbial to forestall development of expanded occurrence of microorganisms. Dynamic material ought not sharpen the scalp and diminish the extent of tingling and scaling. the most objective of article give idea about hairs problem, the way to solve these problems with cost effectiveness and also help to pick the which sort of treatment with selective dosage form preparation as per hairs problem by researcher for society. Keywords Antidandruff, Surfactants, Shampoo, Scalps
Lanjewar et al Journal of Drug Delivery & Therapeutics. 2020; 10(3-s):322-329
ISSN: 2250-1177 [322] CODEN (USA): JDDTAO
Available online on 15.06.2020 at
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Open Access Review Article
Review on Hair Problem and its Solution
Ameya Lanjewar*1,2, Soni Maurya3, Devender Sharma4,5, Anchal Gaur6
1 Department of Pharmaceutical Analysis, Madhyanchal professional university, Bhopal-462044, India
2 Department of Analytical Research and Development (Research officer), Zim Laboratories LTD., Kalmeshwar, Nagpur, Maharashtra-.440013
3 Department of Pharmaceutics, Mumbai educational trust institute of Pharmacy, Mumbai, Maharashtra 400050, India
4 Department of Pharmaceutics, Lovely Institute of Technology (Pharmacy), Lovely Professional University, Punjab -144411, India
5 Department of Pharmaceutics, Goenka College of Pharmacy, Sikar, Rajasthan-332315, India
6 Department of Pharmaceutics, Babu Banarsi Das Institute of Technology, Ghaziabad, Uttar Pradesh- 201206, India
Hair is simple in structure. Hair is formed of an extreme protein called Keratin. Cleanser may be a hair care item, ordinarily as a gooey fluid,
that's utilized for cleaning hair. the problems related with it incorporates male pattern baldness, raucous hair, absence of hair volume, molding,
youthful turning gray, dandruff, diminishing of hair, bluntness then on. Male pattern baldness are often caused due to various reasons, for
instance , hereditary propensities, ecological triggers and presentation to synthetic compounds, medications, healthful inadequacy, outrageous
pressure or long ailment then on. Gentle dandruff can for the foremost part be settled by washing the hair a day with a mellow cleanser hair.
Sedated hostile to dandruff cleanser clean both the hair and scalp and leave the hair reasonable, not bother sebaceous organs. It contains an
enemy of microbial to forestall development of expanded occurrence of microorganisms. Dynamic material ought not sharpen the scalp and
diminish the extent of tingling and scaling. the most objective of article give idea about hairs problem, the way to solve these problems with cost
effectiveness and also help to pick the which sort of treatment with selective dosage form preparation as per hairs problem b y researcher for
Keywords Antidandruff, Surfactants, Shampoo, Scalps
Article Info: Received 08 March 2020; Review Completed 18 May 2020; Accepted 26 May 2020; Available online 15 June 2020
Cite this article as:
Lanjewar A, Maurya S, Sharma D, Gaur A, Review on Hair Problem and its Solution, Journal of Drug Delivery and
Therapeutics. 2020; 10(3-s):322-329
*Address for Correspondence:
Ameya Lanjewar, Department of Pharmaceutical Analysis, Madhyanchal professional university, Bhopal -462044, India
Hair is an important part of human body. The problems
associated with it includes hair loss, unruly hair, lack of hair
volume, conditioning, immature graying, dandruff, thinning of
hair, dullness etc. Hair can vary in shape, length, diameter,
texture, and color. The cross section of the hair could also be
circular, triangular, irregular, or flattened, influencing the curl of
the hair. All mammals have hair. Its main purpose is to regulate
body temperature. It is also wants to decrease friction, to guard
against sunlight, and to act as a way organ. Hair is crowning
glory of a person that plays an important role in the life of
human being. For the scalp, hairs were known as protective
covering in ancient times. From the color, type and amount of
hair, one can be judged as from which society he/she belongs.
Hairs also help in bringing the confidence and pride in a person,
no matter of which genders the person belong. It always had
been the dream of a person to have black, healthy, shiny and
good quality hair. No matter they are long or short and to keep
and maintain them are amongst the priority of all the people. 1,2,
Hair structure
Hair consists of two parts:
1. Follicle
The Follicle is a club shaped structure in the skin. At the top of
the follicle may be a network of blood vessels that provide
nutrients to feed the hair and help it grow. This is called the
papilla. Each follicle arises from an interaction between
epidermis and dermis. Follicle is divided into three segments:
Lanjewar et al Journal of Drug Delivery & Therapeutics. 2020; 10(3-s):322-329
ISSN: 2250-1177 [323] CODEN (USA): JDDTAO
A. Infundibulum: Extends from the surface opening of the
follicle to the level of opening of its sebaceous gland.
B. Isthmus: Extends from the infundibulum to the level of
insertion of the arrector pilli muscle.
C. Inferior segment: The base of bulb is invaginated by a tuff
of vascularized loose connective tissue called dermal
papilla. The papilla of the hair contains many blood vessels
and provides nourishment for hair growth. [3,4,5]
2. Shaft
The hair shaft is divided into three layers:
A. Medulla: It is the middle of hair. it's going to be
fragmented or segmented and continuous or doubled.
It are often a hollow tube or crammed with cells. Most
hairs don't contain a medulla, while other haves
medullas that are discontinuous or fragmented. It
forms the middle of the hair shaft. Fine hairs especially
tend to lack this layer.
B. Cortex: It is largest part of hair shaft which provides the
color to hair i.e. melanin (hair pigment).
C. Cuticle: The cuticle may be a transparent outer layer of
the hairs shaft. It’s made from scales that overlap each
other and protect the inner layers of the hair. The
scales point from the proximal end of the hair, which is
closest to the scalp and to the distal end. 2,3,4,
Figure 1 Structure of hair
Hair Cycle
Each sort of hair undergoes repeated cycle of active growth
and rest. The relative duration of every cycle varies with the
age of the individual and therefore the region of the body
where the hair grows. The cyclic phase of the follicle is
identified by a lively growth period referred to as anagen,
catagen (the intermediate period) and telogen a resting
Anagen phase
The follicle reaches to its maximum length and there is
proliferation of the matrix cells, which produces the internal
root sheath, cortex and medulla of the hair shaft and the
cuticular layers of the hair shaft and the inner sheath. In
epilated anagen hair the inner and outer sheaths are intact
and are wrapped around the bulb portion of the hair.
Catagen phase
The hair in its involutional form, differs from telogen
(clubbed) hair in two ways:
Its keratinized (proximal) part is darker than that of
clubbed hair.
Its inner and outer sheaths are better preserved.
Telogen phase
Hair could also be wrapped within the remains of an
epithelial sac, which is absent from nongrowing,
spontaneously shed clubbed hair of the 100,000 to 105,000
scalp hairs on a person's adult (regardless of sex), 90% are
within the growing or anagen phase. The remaining 10% are
within the resting (telogen) phase. 1,2,5
Product Safety Testing
Cosmeceuticals are used repeatedly and over an extended
period of time. These preparations will need to act as drugs
and cosmetics. Therefore the safety testing criteria of drug
also as cosmetic products are applicable for these
preparations. The test is depends on the sort of product and
ingredients. Some tests are given below. 6,7,8
Chemical irritants
Irritant compound can cause an inflammatory response
immediately on contact or after many day or weeks. The
severity of physiological response may be a results of cellular
antigen antibody reaction and typically depends on the
strength of the irritant and duration of exposure. Usually, the
irritated tissue heals within 2-3 days if the substance is
totally removed testing a cosmeceutical product for its
irritancy potential involve both animal (Draize rabbit test)
and human testing (patch testing). 9,10
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Eye irritation testing
Although cosmeceutical products aren't usually put already
in eye, the accidental contact with such product like face
makeup shampoo and skin cream is high. The tissue of eye
become inflamed when exposed to irritants. The first
preclinical trial to live the ocular irritation of a substance is
that the draize eye irritation test. For this test one eye of
rabbit is treated with the test material while other remains
the untreated control. Irritation read on various eye
structures, including cornea, conjunctiva and iris are
measured at intervals during the subsequent week.
To ensure general safety, ocular irritation is additionally
evaluated within the human eye. One test involves putting
the substance directly into the attention and evaluating for
irritancy potential, another involves ocular evaluation under
actual product use conditions. 11,13
Controlled usage testing
Controlled usage testing provides additional information
which animal or patch testing don't yield. For this sort of
volunteers receive the merchandise and use it throughout a
define period (2-8 week) subjects are evaluated regularly
and are asked to supply subjective data. This method
provides an irritancy potential of fabric under conditions
that reflects how consumer would use the merchandise. 12,14,
Hair Problem
Hair Loss
Although historically discussed as a haul among men, hair
loss/thinning hair is additionally common among women. for
several men, it's getting to be male pattern balding. Female
hair loss is typically caused by stress, medication, changing
hormones, and even menopause. Additionally, many hair
styling products (chemicals/excessive heat) can contribute
to hair loss. 12,14, 16
Dry Hair
Shampooing too often causes dry hair. Although squeaky
clean hair may be a good thing, many overdo it by washing
once, sometimes twice or per day which will strip away all of
the hair’s natural oils.
Spit Ends
Over-brushing hair, excessive perming, too much heat, and
lack of a good conditioner cause split ends.
Oily/Greasy Hair
Oily hair is caused when the scalp produces an excessive
amount of natural oil called sebum. Sebum is produced by
sebaceous glands, which may sometimes “work overtime”,
leading to excessive amounts of oil.
Frizzy Hair
Frizzy hair occurs when the hair’s moisture level falls below
normal levels, and it can also be hereditary.
Dull Hair
There are many causes of dull-looking hair chemical or heat
styling damage, and environmental soils.
Heat Damaged Hair
Use your curling iron or flat iron too much and your hair will
become damaged.
Colour Damaged Hair
When you colour your hair, chemicals are used to open your
hair shaft, leaving your hair extremely porous and prone to
brittleness and breakage.
Gray Hair
To many, gray hair is a badge of honor. But others would
prefer to get rid of it because gray hair can be brittle and
more unruly than other strands. 17,18
Dandruff is little white pieces of dead skin in someone’s hair,
or fallen from someone’s hair. It’s apparently caused by a
fungus called Malassezia restricta and Globosa malassezia
formerly called Pityrosporum may be a yeast causing
infection of skins and scalp. It’s caused by not brushing hair,
allergy , stress, not showering enough etc. 1,20,21
There are two types of dandruff
Dry dandruff
Dry (universal) dandruff known to be caused by Pityri as is
simplex and is characterized by excessive development of
minute scales of white grayish or ash color accumulate on
the scalp area. Scales visible on the scalp are divided cells of
keratinised layer whose renewal cycle is pathologically
compact. During this sort of dandruff, no excessive hair loss
is observed. 6,18
Oily dandruff
Other sort of dandruff is named oily dandruff or Pityriasis
steatoides. It arises on the scalp skin with varied intensity of
sebum production. It appears mainly frequently in young
men next puberty. Inflammation of various intensity
develops on the scalp skin alongside the looks of oily scales
of dirty yellow colour which will form lesions. These lesions
are often related with pruritis of various intensity. Hairfall is
ordinary. It’s going to also exacerbate androgenetic alopecia,
the foremost common site suffering from this sort of
dandruff is scalp but it can arise among eyebrows along the
side of nose behind the ears over the breastbone and
sometimes within the armpits. 22,23, 24
Cause of Hair problem
Life vicissitudes, including illness, emotional trauma, protein
deprivation (during strict dieting), and hormonal changes like
those in pregnancy, puberty, and menopause may cause hair
Several health conditions, including thyroid disease, iron
deficiency anaemia, and syphilis, can cause hair loss. While
thyroid blood tests and other lab tests, including an entire blood
count (CBC), on people that have ordinary hair loss are usually
normal, it's important to exclude treatable causes of hair loss.
Hair loss is typically related to one or more of the following
High fever
Sudden weight loss (crash dieting)
Severe illness
Severe emotional stress or loss.
Family history (heredity)
Lanjewar et al Journal of Drug Delivery & Therapeutics. 2020; 10(3-s):322-329
ISSN: 2250-1177 [325] CODEN (USA): JDDTAO
Hormonal changes and medical conditions.
Medications and supplements.
Radiation therapy to the head.
Hairstyles and treatments.
Stressful event
Hair loss can appear in many various ways, counting on
what's causing it. It can come on suddenly or gradually and
affect just your scalp or your whole body. Some sorts of hair
loss are temporary, and others are permanent. 1,6,23
Signs and symptoms of hair loss may include:
Gradual thinning on top of head
This is the foremost common sort of hair loss, affecting
both men and ladies as they age. In men, hair often
begins to recede from the forehead during a line that
resembles the letter M. Women typically retain the
hairline on the forehead but have a broadening of the
part in their hair.
Circular or patchy bald spots
Some people experience smooth, coin-sized bald spots.
This sort of hair loss usually affects just the scalp, but it
sometimes also occurs in beards or eyebrows. In some
cases, your skin may become itchy or painful before the
hair falls out.
Sudden loosening of hair
A physical or emotional shock can cause hair to loosen.
Handfuls of hair may begin when combing or washing
your hair or maybe after gentle tugging. This sort of
hair loss usually causes overall hair thinning and not
bald patches.
Full-body hair loss
Some conditions and medical treatments, such as
chemotherapy for cancer, can result in the loss of hair
all over your body. The hair usually grows back.
Patches of scaling that spread over the scalp
This is a sign of ringworm. It may be accompanied by broken
hair, redness, swelling and, at times, oozing.23
Figure 2 Symptoms of Hair loss
Most baldness is caused by genetics (male-pattern baldness
and female-pattern baldness). This type of hair loss is not
These tips may help you avoid preventable types of hair loss:
Avoid compulsively twisting, rubbing or pulling your
Treat your hair gently when washing and brushing. A
wide-toothed comb may help prevent pulling out hair.
Avoid tight hairstyles, such as braids, buns or ponytails.
Avoid harsh treatments such as hot rollers, curling irons,
hot oil treatments and permanents.
Stop smoking. Some studies show an association between
smoking and baldness in men.
If you are being treated with chemotherapy, ask your
doctor about a cooling cap. This cap can reduce your risk
of losing hair during chemotherapy.
Avoid medications and supplements that could cause hair
Protect your hair from sunlight and other sources of
ultraviolet light.
Although hair issues certainly vary from person to person, by
following these simple steps, these common problems are
easily repairable. Your hair problems will soon be a thing of
the past and you will get on your thanks to an excellent head
of hair before you recognize it. If you're busy and don’t have
time, you'll always get your hair done at a beauty school
Shampoo could also be defined as a preparation containing
surface active agents which remove dirt, grease and debris
from the hair, scalp and other parts of body without affecting
the natural gloss of hair. Shampoo is described as a cosmetic
preparation meant for the washing of hair and scalp, packed
within the form for convenient use. Shampoo is liquid or
cream preparation of soap or detergent wash hair and scalp.
Shampoo may produce lubrication, conditioning, and drugs
etc. 1,12,19
There are many different type of shampoo is available as it is,
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Powder shampoo
Clear liquid shampoo
Liquid cream or lotion shampoo
Jelly shampoo
Aerosol shampoo
Baby shampoo
Medicated anti-dandruff shampoo
Cream or paste shampoo
Conditioning shampoo
Ideal characteristics of Shampoo
1. Remove debris
Generally debris is not removed by using simply water,
whereas it is often removed easily by use of shampoo.
Water can remove most visible dirt and debris, but won't
eliminate odoors or oily deposits. Shampoo helps water
remove dirt, debris and odors like smoke or sweat
2. Lathering power
3. As stated earlier good foaming is important for a
shampoo based because it has psychological value. a
neighborhood from psychological value, foam allows
assessment of the quantity of shampoo required to
make sure that each one functions involved in
cleansing are performed.
4. Speed of drying
Drying of the hair in shampooing is that the most, tedious
process. Some detergent leave the hair very wet, dry very
slowly, other leave behind a hydrophobic surface which
may shed water early and thus making drying process
faster. 17,18
5. Safety
Although cosmeceuticals products aren't usually put
already within the eye, the accidental contact with such
product like face structure shampoo and skin cream is
high. The tissue of eye become inflamed when exposed to
irritants. The detergent based should be non-irritating and
non-toxic to the scalp. 17,18
6. Face of combing wet hair
Combing of wet hair will evaluate roughness and tangling
tendency immediately after treatment with the detergent
but simple removal of the oily material is not the whole
story. A desirable detergent based should leave the wet
hair in a condition where it will be easy to comb wet hair.
7. Luster of the hair
Soap in hard water is likely to leave dull films of insoluble
calcium and magnesium soaps on the hair. Some
detergents with insufficient suspending power may
redeposit dirt or grease on the hair with dulling effect.
Detergent based should not leave dulling material on the
hair after shampooing become lustrous.
8. Well preserved and good stability
The product must be properly preserved against bacterial
and fungal contamination. It should have good stability for
at least two to three years at room temperature.
9. Easy rinsing
Some detergent based can be rinsed easily while other
continues lathering and rinsing appears endless.
10. Economical
The product should not be over formulated. The
formulation should be as simple and cost effective as
possible, using only those raw materials that are easily
available and are necessary to accomplish the desired
11. Efficient soil removing
Detergent base for shampoo should remove grime, oil,
scalp debris etc. in soft and hard water. In vitro study on
this aspect may be carried out by hair switches soiled with
synthetic sebum.
12. Ease of application spreading
A shampoo made with a detergent base should be easy to
spared i.e. it should be distributed over the hair.
13. Good stability
The product should have good stability for at least two or
three years at room temperature as well as when stored in
daylight or in warehouses with low or high ambient
14. Low level of irritation
The formulator should try to accomplish all of the above
qualities while keeping the irritations level as low as
15. Easy of combing and setting the dry hair
After rinsing, the hair should be combing easily without
tangling. The hair should have body when dry, that is hair
should not be limb or over conditioned.
Evaluation Parameter of Shampoos
The pH of shampoos has been shown to be important for
improving and enhancing the qualities of hair, minimizing
irritation to the eyes and stabilizing the ecological balance of
the scalp. The present trend to market shampoos follower pH
is one among the ways to attenuate damage to the hair. Mild
acidity prevents swelling and promotes tightening of the
scales, there by inducing shine. 6,7,18
Percent of Solids Contents
If the shampoo has too many solids it will be hard to work
into the hair or too hard to wash out.
Rheological evaluations
The results of rheological evaluation showed that the
viscosity of the samples changes gradually with the rise in
rpm, therefore the shampoo formulations were time
dependent. Secondly because the data showed the viscosity
decreases with increase in rpm, therefore the shampoo
formulations were shear thinning or pseudo plastic in
Detergency ability
Although cleaning or soil/sebum removal is that the primary
aim of a shampoo, experimental detergency evaluation has
been difficult to standardize, as there's no real agreement on
a typical soil, a reproducible soiling process or the quantity
of soil a shampoo should ideally remove.
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ISSN: 2250-1177 [327] CODEN (USA): JDDTAO
Foaming ability and foam stability
Although foam generation has little to try to to with the
cleansing ability of shampoos, it's of paramount importance
to the buyer and is therefore a crucial criterion in evaluating
Raw Materials Required For Preparation of
Surfactants are used to enhance the foaming property of
shampoos. Four different types of surfactants are available in
the market.13
Cationic surfactants
Cationic detergents produce foam well and have reasonable
cleansing power. They also leave hair luster and freed from
electrosing charge. It would, therefore, appear that cationic
detergents are ideal for shampoos. But thanks to its tendency
to corrnal eye tissues, they are not used frequently in
shampoos. Examples are quaternary ammonium salts,
amines with amide linkages.
Non-ionic surfactants
Non-ionic detergent have sufficient cleansing power but only
a couple of have sufficient foaming properties. Therefore,
these aren't used as principal foaming agents. However,
these have remarkable foam booster and stabilizing
properties and intrinsically, are used as foam boosters and
stabilizers. These are mild and non-irritating to the skin.
Some newly developed non-ionics possess good foaming
power and may be used as principal foaming agents.
Examples are carboxylic esters, glycol ester of carboxylic acid
, anhydrosorbitol ester. 6,7,18
Anionic surfactants
Anionic surfactants include a number of class of compounds
out of which important ones are mentioned here in context
with hair preparations. Examples are carboxylates,
sulphonates, alkyl sulphates.
Amphoteric surfactants
Amphoteric surfactants are known for their mildness and are
used in mild shampoos. These are compatible with wide
range of surfactants. Examples are N-alkyl aminoacids,
betaine, alkyl imidazolines, N-coco 3-aminopropionic acid.
Viscosity modifier
These agents improve the viscosity of formulation. Examples
are electrolytes likes ammonium chloride and Sodium
chloride,Natural gum likes gum karaya and gum tragacanth,
cellulose derivatives like Hydroxyethyl cellulose,
hydroxypropyl cellulose, carboxymethyl cellulose. Others are
TEA soaps, alkanolamides, phosphate esters, amidoamine
oxides. 1,28,29
Opacifying and Clarifying agents
A number of materials can be used for opacifying or giving
pearlescent effect. May improve by solubilizing alcohols,
phosphates or non-ionic solubilizers. Examples are
Propylene glycol, glycerol monostearate, palmitates, ethanol,
isopropanol esters.
Conditioning agents
These agents are intended to improve manageability, feel &
luster of the hair. The materials which have been claimed to
have conditioning effect on hair. Examples are lanolin,
mineral oil, and natural products like polypeptides, herbal
extracts, resins, quaternary compound, silicon, and lecithin.
Sequestering agents
It used to prevent deposition of calcium and magnesium salts
of soaps on to the hair. Examples are EDTA salts,
polyphosphates, citric acid.
There are two important aspects which should be
ascertained before final selection of fragrance for shampoos.
Fragrance must be soluble in shampoo and it should be
compatible with it. Examples are herbal, fruity or floral
fragrances can be used in shampoo. 17,18
Surfactant in shampoos tends to interfere with bactericidal
activity of antibacterial in order that high concentrations of
preservatives are necessary in shampoos. Many manmade
products are susceptible to microbial attack, if not preserved
efficiently. Bacterial growth in shampoos can cause
breakdown of detergents in shampoo leading to
discoloration of the merchandise. One important fact to be
kept in mind while selecting preservatives for shampoos is
that surface in shampoo tend to interfere with bactericidal
activity of antibacterial therefore higher concentration of
preservatives are necessary in shampoos. Examples are
parahydroxy carboxylic acid, alcohol, formaldehyde,
benzoate of soda, butyl paraben. 1,12,19
1. Conditioner is that the backbone of one's hair-care
routine. Conditioner refortifies the cuticle with a
protective coating, allowing the hair to stay growing
and not break easily. When the hair is exposed to the
surface world, the cuticle, or outer lining, gets damaged
until it ultimately breaks; the conditioner fills in those
injuries and coats the hair to help the cuticle.
Conditioner may be a conditioning or moisturizing
agent generally made from ingredients like silicones,
oils, and emollients, also as cationic surfactants. When
combined, these ingredients replenish hair's moisture.
There are various sorts of conditioner, too. Of the
foremost common are in fact your traditional post-
shampoo hydrator; deep conditioner, which is nearly
sort of a hair mask therein it's meant to be left on
longer so as to penetrate the strands more deeply.
2. Cleansing conditioner
Which acts as shampoo and conditioner hybrid that
simultaneously cleanses and conditions the hair; and leave-
in conditioner, a post-shower, no-rinse treatment that
nourishes and protects the hair throughout the day.
3. Dry conditioner
According to cosmetic chemist Ron Robinson, is designed to
spritz on just enough to make your hair shinier, smoother,
and softer, without the risk of over applying or making hair
greasy. 1,5,28
Home remedies:
1. Egg mask
Eggs are rich in sulphur, phosphorous, selenium, iodine, zinc
and protein, which together help promote hair growth.
Lanjewar et al Journal of Drug Delivery & Therapeutics. 2020; 10(3-s):322-329
ISSN: 2250-1177 [328] CODEN (USA): JDDTAO
2. Liuorice root
This herb prevents hair loss and further damage to the hair.
It helps soothe the scalp and get rid of any dry
3. Coconut Milk
The protein and essential fats in it promote hair growth and
prevent hair loss.
4. Green tea
This tea is rich in antioxidants, which help boost hair
growth and prevent hair loss.
5. Beetroot juice
Beetroot is rich in vitamins C and B6, folate, manganese,
betaine and potassium, all of which are essential for healthy
hair growth. Besides, it acts as a detoxification agent by
helping keep the scalp clean.
6. Aloe Vera
Aloe Vera is an effective home remedy for hair loss and to
boost hair growth. It is also effective in reducing problems
of scalp like itching and flaking.
7. Fenugreek seeds
Fenugreek or Methi seed is among the foremost effective
home remedies to prevent the hair loss. It repairs the hair
follicles and helps in re-growth of the hair.
8. Onion juice
The antibacterial properties of onions help fight against
scalp infections, while the sulfur content improves
circulation blood to the hair follicles. It promotes hair
growth and controls loss of hair.
9. Amla
Indian Gooseberry or Amla is another effective home remedy
to prevent hair fall. one among the causes is that the
deficiency of vitamin C , hence consuming amla will
strengthen the hair follicles and assist you to regulate it.
Because of its anti-inflammatory and therefore the
exfoliating properties, amla help promote faster growth of
hair, maintain a healthy scalp and prevents premature
greying. 20,21,22
Tips for controlling hair loss
Diet and Exercise
You need to feed your hair all the right nutrients particularly
plenty of protein and iron. However, along with eating
a balanced diet ensure you are exercising side by side. Yoga
and meditation are effective in reducing hair fall. And make
them brittle.
Chemical Treatment
Undergoing rigorous hair treatments like straightening,
perming and colouring is certainly not kind to your tresses.
Further avoid using blow dryers, curling rods, especially on
wet hair as they really boil the water in your hair shaft and
make them brittle.
Oiling improves blood circulation and nourishes the roots.
Confirm to massage your tresses once every week with oil
that suits your scalp. Cover it with a cap and wash it off with
a light shampoo after two hours.
Too many styling products
Using too many chemically laden products on your hair could
prove harmful within the end of the day. It’s best to offer
them an opportunity and check out natural homemade
insteads racipes. 1,5,28
Diet for healthy hair
While treatments and shampoos do play a role in
maintaining healthy hair, the secret to thick, shiny, strong
tresses is a healthy diet.
Iron deficiency is that the main explanation for hair falls.
Spinach isn't only an excellent source of iron but also vitamin
A, C and protein. It also contains sebum which acts as a
natural conditioner for hair and provides us with omega-3
acid, magnesium, potassium and calcium. These help in
maintaining a healthy scalp and lustrous hair.
Known to be good for the eyes, carrots contain vitamin A that
also improves hair growth. Deficiency of vitamin A may
cause dry and itchy scalp. Carrots are known to feature to the
thickness of hair, make hair lustrous, improve blood
circulation, strengthen the hair, protect hair from external
damages like pollution and also help prevent breakage of
hair and hair fall.
Since hair consists of 68 percent keratin protein, eggs help in
rebuild damaged hair. They’re also rich during a B-complex
vitamin called biotin that helps hair grow.
Oats are rich in fibre, zinc, iron, omega-6 fatty acids and
polyunsaturated fatty acids (PUFAs) that stimulate hair
growth and will make your hair thick and healthy.
Walnuts contain biotin, B vitamins (B1, B6 and B9), Vitamin
E, many protein and magnesium - all of which strengthen
hair cuticles and nourish the scalp. It helps protect your cells
from DNA damage which can be caused thanks to sun
Lentils are an excellent source of protein, iron, zinc, and
biotin. They are also loaded with vitamin B and C which is
important for restoring the health of red blood cells that
provide the skin and scalp with much needed oxygen.
Lean meats like chicken or turkey are rich in high-quality
protein which strengthens fragile hair and prevents
Strawberries and guavas
Strawberries contain high levels of silica. Silica may be a
trace mineral vital for hair strength and hair growth. Other
foods rich in silica include rice, oats, onion, cabbage,
cucumber and cauliflower. Vitamin C also prevents hair from
becoming brittle and breaking. While we frequently consider
oranges because the best source of vitamin C, one guava
packs four to 5 times the maximum amount.
Lanjewar et al Journal of Drug Delivery & Therapeutics. 2020; 10(3-s):322-329
ISSN: 2250-1177 [329] CODEN (USA): JDDTAO
Yogurt is packed with Vitamin B5 and Vitamin D that are
known to promote hair follicle health.
Sweet potatoes
Beta carotene protects against dry, dull hair and stimulates
the glands in your scalp to form an oily fluid called sebum.
Orange coloured fruits and vegetables like carrots, pumpkin,
cantaloupe, mangoes and sweet potatoes are an excellent
source of this. 22,23,24,25,26
This review gives knowledge about detail chemistry hairs
with its problems and also provides their solutions. This text
also main specialize in the hair problem and with its
solutions like allopathic, other remedies. It helps to
researcher to seek out area of problems where easy to
solution concerning hairs and also provides selection best
polymers utilized in the preparation of dosage form for
treating the hairs problems with cost effectiveness and its
better stability with selecting proper preservatives. It also
helps within the formulation of shampoo with its ideal
1. Gahlawat J, Sharma D, Thakur GS, Chobdar J, Sharma V.
Formulation and evaluation of polyherbal liquid shampoo.
European Journal of Biomedical and Pharmaceutical Sciences.
EJBPS. 2019, 6(7):149-154.
2. Fuchs E, Alonso L. The hair cycle. J. cell Sci. 2006; 119:391-
3. Ross J and Miles GD. An apparatus for comparison of foaming
properties of soaps and detergents. Oil Soup, 1941; 18(5):99-
4. Shah P, Dasani S. Preparation of herbello-an herbal
antidandruff shampoo. IJPBS, 2015; 5(2):220-228.
5. Andl T, Reddy S.T, Gaddapara T, Millar S.E, WNT. Signals are
required for the initiation of hair follicle development.
Developmental Cell 2002; 2(5):643-653.
6. Gaud R.S. and Gupta G.D., Practical Physical Pharmacy, 1st ed.,
C.B.S. Publisher and Distributer, New Delhi, 2001; 81-105.
7. Balsam M.S, Sagarin E, Gershon S.D, Rieger M.M. 2008,
Cosmetics- Science and Technology, 2nd edition, Vol. 2
Published by Wiley India Pvt. Ltd. New York, PP 174-184.
8. Mitsui T.1997, New cosmetic science, 1st edition, Published by
Elsevier Science Amsterdam The Netherlands PP 47-64.
9. Johnson D.M. 1997, Hair and Hair Care, Cosmetic Science and
Technology series Vol. 17, P ublished by Library of Congress
CatalogingMarcklDekkar Inc. New York. PP 13-30.
10. Potluri A, AsmaShaheda SK, NeeharikaRallapally, Durrivel S,
and Harish G.A, Review on herbs used in anti -dandruff
shampoo and its evaluation parameters. Indo American J.
Pharm. Res. 2013; 3266-3278.
11. Rieger M.M, Banker G.S. Pharmaceutical dosage forms:
Disperse system. Encyclopedia of Pharmaceutical Technology.
Marcel Decker, New York. 1988; 3:361-373.
12. The Drug and Cosmetic Act, 1940 ACT NO- 23 OF 1940 1
Published by Ind. Drug Manufacturers Association. 2005. PP 1-
13. Zeffren E, Method for the coloring of hair. Cosmetic and Toilet.
1983; 98(1):48-56.
15. Agkerman A.B, Kligman A.B. Some observation on dandruff. J.
Soc. Cosmetic Chemists, 1967; 20:81-108.
16. Sharma P P. 2008, Cosmetics- Formulation, manufacturing and
quality control, 4th edition, Published by Vandana Publication
(P) Ltd. Delhi-110088 Page no 323- 348.
17. Croxtall J D, Plosker G L. Sertaconazole A review of its use
Antimicrob Agent Chemother, 2009; 69(3):339-359.
18. Han SH, Hur MS, Kim MJ, Jung WH, Park M, Kim JH, Shin HJ,
Choe YB, Ahn KJ, Lee YW. In vitro anti-malassezia activity of
castaneacrenata shell and oil-soluble glycyrrhiza extracts.
Annals of Dermatology. 2017; 29(3):321-326.
19. Itankar P, Murkute AV. Evaluation of in vitro antidandruff
activity of biotransformed material (extract) of
nicotianatabacum leaves. J.Natural Remedies. 2015; 15(2):65-
20. Naga Padma P, Anuradha K, Divya K. Comparison of potency of
antifungal action of dandruff shampoos and different plant
extracts. International J. Medical Res &Health Sci. 2015;
21. Al Badi K, Khan SA. Formulation, evaluation and comparison of
the herbal shampoo with the commercial shampoos. Beni-suef
University J. Basic and Applied Sci. 2014; 3(4):301-305.
22. Mohamed HS, Farahat NH, Megallaa NG, Elhaleem MA. Nursing
guidelines on hair dandruff symptoms for adult patients. Life
Science Journal. 2014; 11(1s):323-333.
27. Nafisy AT. A Review of traditional medicine in Iran. Isfahan:
Isfahan University Publications, 1989; 133.
28. Abbiw DK. Useful plants of Ghana West African use of wild
and cultivated plants. Intermediate Technology Publications
and the Royal Botanic Gardens Kew, 1990.
29. Hadkar U.B. and Ravindera R.P., Indian Journal of
Pharmaceutical Education Research, 2009; 43(2):187-191.
... Only the fingers, soles, and palms of the human body lack hair. Among its various roles, hair controls body temperature, lessens friction between hair shafts, protects from sunlight, and defends against environmental factors [11]. Carbon is one of the chemical components of the fibrous alpha-keratin proteins that make up hair. ...
... As depicted in Figure 1, the bulb surrounds a cone-shaped structure, known as the dermal papilla that is located near the hair follicle's base. It contains blood vessels and connective tissue that nourish the hair with nutrition and stimulate its growth [11]. The dermal papilla contains mesenchymal cells and epithelial cells [13]. ...
... The cortex is the part of a shaft between the cuticle and the medulla [11]. Most of the hair shaft, or 75%, is made up of the cortex. ...
Full-text available
Polymer, lipid, and natural protein-based hair care nanocarriers are in preclinical testing. Nanomedicine has enhanced therapeutic efficacy and decreased side effects. This review examines herbal nanomedicine for hair care. We also reviewed the hair cycle, its morphology, and the mechanisms of herbal-based medicine that regulate the hair cycle to treat hair loss. Nano-formulations have better solubility, permeability, therapeutic efficacy, and prolonged distribution than standard herbal medicines. This review also discussed the nanotechnology barrier and nano formulations for hair loss and growth and includes a recent herbal nanomedicine study. Researchers interested in using herbs to treat hair problems and clinically translating hair care products may find the results presented significant.
... It always had been the dream of a person to have black, healthy, shiny and good quality hair. No matter they are long or short and to keep and maintain them are amongst the priority of all of the people [43]. ...
... x Inferior segments: The base of the bulb is invaginated by a tuff of vascularized loose connective tissue called dermal papilla. The papilla of the hair contains many blood vessels and provides nourishment for hair growth [43]. ...
... It's made from scales that overlap each other and protect the inner layers of the hair. The scales point from the proximal end of the hair, which is closes to the scalp and to the distal end [43]. ...
Full-text available
This study concluded that the combining extracts of Hibiscus rosa sinensis, Withania somnifera, Eclipta alba, Olea europea and Nigella sativa were used in different composition to get multipurpose effects on scalp and hair such as antimicrobial, prevent hair fall and increased hair growth and prevent greying of hair.
... TULSI 20,23,36,38 Ocimum sanctum Linn (Tulsi) as an odoriferousherb. It belongs to the family Labiatae. ...
... Chemical constituents: It contains hentriacontane, betaine, beta-sitorol, achyranthes saponins A, achyranthes saponins B, achyranthes saponins C, achyranthes saponins D. 20 4,7,10,11,13,18,20,22,23,27,28,33,37,38 ...
... Botanical Description of Neem, Turmeric, Aloe Vera, Apamarg23,31,32,34,36,38 ...
Full-text available
Nowadays teeth related disease is common among all ages of people and children. Ten out of five children are suffering from tooth decay due to the consumption of more sweets, chocolates, and eatable items by children. Various eatables affect the teeth and decay the teeth rapidly, so we need to understand the phenomena of diseases which is responsible for infection in teeth. Main objective of this review project is to collect the information and role of various herbal drugs used in Dental Care and for its management. Also represent systematic plant profile which not only useful in treatment of the teeth but also give the phytochemicals and therapeutic information of plants used the in management of teeth diseases.
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Malassezia furfur is reported as most common etiological agents causing Dandruff-a common skin condition that affects the scalp and hair. Several herbs are reported to be effective in controlling such fungi. In our laboratory an antidandruff herbal shampoo-Herbello was prepared and characterized. Certain improvements, specially with respect to viscosity, conditioning ability and antidandruff activity were needed. Therefore, aim of the present work is to improve the prepared shampoo. The active ingredients of various herbs were extracted and checked for their efficacy against Malassezia furfur. Most effective herbs were chosen and used in different combinations for preparation of shampoo in order to improve antidandruff activity. Various formulation of antidandruff herbal shampoo were tried out and best combination was chosen for stability testing. After stability test Herbello was provided to volunteers as samples and feedback obtained were analyzed.
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Background A new shampoo with anti-Malassezia properties obtained from various plants is required to provide seborrheic dermatitis patients with a wider range of treatment options. Objective The aim of this study was to obtain in vitro susceptibility profiles of Malassezia restricta and M. globosa, the most important pathogenic organisms in the development of seborrheic dermatitis, to the plant extracts used in commercial anti-dandruff shampoos. Methods Minimal inhibitory concentrations (MICs) were determined for eight candidate plant extracts and two plant-derived natural products diluted with Leeming and Notman medium to final concentrations of 0.016 to 1 mg/ml. Results Castanea crenata shell, Camellia sinensis leaf, and oil-soluble Glycyrrhiza extracts presented relatively low MIC values (≤0.5 mg/ml) against both strains. The C. crenata shell and oil-soluble Glycyrrhiza extracts demonstrated especially high anti-Malassezia activity, suggesting their potential use in the treatment of seborrheic dermatitis. The extracts also showed fungistatic activity against other common facultative pathogenic yeasts, Cryptococcus and Candida. Conclusion C. crenata shell and oil-soluble Glycyrrhiza extracts could potentially be used as active ingredients in anti-seborrheic and anti-dandruff shampoo formulations. They could be helpful for repeated treatments and regular prophylaxis of scalp seborrheic dermatitis.
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The methods of preparing new derivatives of known substrates were applied to modify organic compounds like Carbohydrates, steroids, sterols, terpenoids, flavonoids, alkaloids, antibiotics, amino acids etc. Such alteration encompasses many changes in the substrate moiety by the addition, degradation or modification. When basic structure of resultant molecule remains unaltered, the microbial biotransformation can be applied for formation of desired derivatives of precursor. Aim: To determine the in-vitro anti-dandruff activity of biotransformed material of Nicotiana tabacum leaves. Material and Method: The collected leaves about 200 g were macerated in cow urine (1 L) for time period of 28 days. After the completion of this time period, the biotransformed material was harvested, lyophilized and powdered (20 g). Regular aqueous extract of the leaves was also prepared for comparative study. Various concentrations, such as 12.5, 25, 50, 100, 500 mg/ml, of aq. extract and biotransformed material of Nicotiana tabacum leaves were prepared and tested for in vitro anti dandruff activity using strain of Malassezia (Pityrosporum) furfur and compared with marketed ayurvedic, homoepathic and allopathic (Ketoconazole 2 %) formulations. Result: The regular extract and the biotransformed material were screened for phytochemicals. It showed the presence of alkaloids, prominently. The strains responsible for the biotransformation process were also evaluated and identified as Bacillus licheniformis and Bacillus megaterium . The biotransformed material of Nicotiana tabacum leaves shows promising effect against Malassezia (Pityrosporum) furfur , in terms of zone of inhibition of about 7 mm at 100 mg/ml 26 mm at 500 mg /ml, respectively. The results were found promising as compared to the regular aqueous extract, marketed formulations including Ketoconazole 2 % preparation. Conclusion : The study shows the improved potential of the cow urine biotransformed material over the normal extract of the same plant. It was evident that the dandruff growth was significantly inhibited by treatment with biotransformed material. Hence, in vitro studies of microbial biotransformed Nicotiana tabacum leaves was found to have a potential anti-dandruff activity between 100 mg/ml to 500 mg/ml, compared with its aqueous extract, marketed ayurvedic, homoepathic and allopathic formulations.
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Context: Dandruff a very common scalp disorder with high prevalence in population is caused by numerous host factors in conjunction with Malassezia furfur. Most of the commercially available anti-dandruff hair shampoos contain some form of antifungal agent(s) that appear to reduce the incidence of the disease. There are no good scientific studies done to prove the antifungal activity of commercially available hair shampoos. Aim: In this study commercially available shampoos were assessed for antifungal activity against a human dandruff isolate of M. furfur. The shampoos were Head & Shoulders, Clinic All Clear, and Pantene etc. The results demonstrated that all six of the assayed hair shampoos have some antifungal effect on growth of M. furfur. These products have poor efficacies, more side effects and give scope for recurrence of symptoms. Methods and Materials: Therefore different plant extracts that possess various active compounds which have antifungal activity could help to overcome the incidence of the disease and also avoid the emergence of resistance in the pathogen. The plant extracts were tested in different concentrations like 1:5, 1:10, 1:20 and they were hibiscus, neem, soap nut, etc. The inhibitory action was studied using agar well assay and disc diffusion method and the results indicated in percentage of inhibition. Conclusion: The study was significant as not only efficient known plant products with anti-dandruff activity could be compared with commercially available shampoos but also their better efficacies at minimum concentrations could be identified. This can help make a polyherbal mixture that could be incorporated in hair oil or shampoos for better anti-dandruff activity.
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The study aimed to formulate a pure herbal shampoo and to evaluate and compare its physicochemical properties with the marketed synthetic and herbal shampoos. The herbal shampoo was formulated by adding the extracts of Acacia concinna, Sapindus mukorossi, Phyllanthus emblica, Ziziphus spina-christi and Citrus aurantifolia in different proportions to a 10% aqueous gelatin solution. Small amount of methyl paraben was added as a preservative and pH was adjusted with citric acid. Several tests such as visual inspection, pH, wetting time, % of solid contents, foam volume and stability, surface tension, detergency, dirt dispersion etc, were performed to determine the physicochemical properties of both prepared and marketed shampoos. The formulated herbal shampoo was also evaluated for conditioning performance by administering a blind test to 20 student volunteers. The formulated herbal shampoo was clear and appealing. It showed good cleansing and detergency, low surface tension, small bubble size and good foam stability after 5 min. The prepared shampoo and commercial shampoos showed comparable results for % solid contents also. The score of the conditioning performance of the tress washed with herbal shampoo was found to be 3.0 out of 4, while the score of the marketed synthetic and herbal shampoo was 3.4 and 3.3 respectively. The results indicated the formulated shampoo is having excellent conditioning performance, at par with commercially available shampoo. However, further research and development is required to improve it's quality and safety.
1. The measurement of the foaming properties of soaps and detergents is shown to be possible by comparing the relative stability of a foam by measuring the effect of an arbitrary standard destructive mechanism acting upon a volume of foam during production under standard conditions and protected from adventitious destructive forces. 2. A simple apparatus and procedure for carrying out foam tests has been described and the reproductibility of the test evaluated. 3. Previous studies of foam comparison have been reviewed and criticisms offered regarding the procedures and conceptions involved.
Hair follicle morphogenesis is initiated by a dermal signal that induces the development of placodes in the overlying epithelium. To determine whether WNT signals are required for initiation of follicular development, we ectopically expressed Dickkopf 1, a potent diffusible inhibitor of WNT action, in the skin of transgenic mice. This produced a complete failure of placode formation prior to morphological or molecular signs of differentiation, and blocked tooth and mammary gland development before the bud stage. This phenotype indicates that activation of WNT signaling in the skin precedes, and is required for, localized expression of regulatory genes and initiation of hair follicle placode formation.