In the proposed article, a real-time ECG acquisition system using two electrodes has been proposed. Most of the available acquisition system depends on at least three electrodes. In this work, two-electrode system has been studied in details, and minimal system to overcome the problems has been designed and presented in the proposed work. Issues of impedance matching, power-line noise, and
... [Show full abstract] high-frequency noise due to muscle activity have been analyzed, and the proposed system has been designed to overcome the addressed issues. The proposed work presents a novel way for acquisition of ECG from palms using only two electrodes and at the same time overcoming the issues related to impedance matching and muscle noise.