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Symptomatic COVID-19 positive and likely patients treated by homeopathic physicians - an Italian descriptive study

Authors:
  • SIMO - Società Italiana di Medicina Omeopatica
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Abstract

In Italy most positive and probable COVID-19 patients are at home if their clinical situation is mild. A group of homeopathic physicians treated 50 patients.The study describes their hospitalization rate, clinical evolution, homeopathic medicines used and gives an updated picture of use, limitations and perspectives of classical homeopathy in COVID-19 extrahospital patients
Scienc communicaon to medical colleagues
Symptomac COVID-19 posive and likely paents treated by homeopathic physicians - an
Italian descripve study
Introducon1:
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-")'.)
')7"'.'$'
7level of hospitalizaon of COVID-19 paents treated by doctors with
addional experse in homeopathy.14
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U"(('RR'$
6)MUN#(
0'.6")'
($$6
8??'''(((??$?6??22%.$($
9;J2.MN
;G?;;%GFO
8??'''(((??)?.

10 Task Force COVID-19 of the Department of Infectious Diseases and Informatics Service, Istituto Superiore di
Sanità. COVID-19 Epidemic, National Update: 30 March 2020
https://www.epicentro.iss.it/coronavirus/bollettino/Bollettino-sorveglianza-integrata-COVID-19_6-aprile-2020.pdf
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>:)(0)'$)'"
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'"))"'
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Method:
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posive or probable COVID-19"$'$")>"
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$" "suspected", "probable" and "conrmed" cases. 6
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The clinical records '10 6))$
40))(
%$ '(0'77
$7')
$<*(
;I'>)"
'$(
,'$$$
)(
")).
)$(
A$)D06$$
)"$)$$
$(
<)'single homeopathic remedies
M')"<VN
(0$""'6>
(
16A,:)(MN(3$$)'
"+(A,:)(8??('(???55#?--#5
*)"$'7)$
)$)"
(
Inclusion criteria:
))))'M6)N"
))'three )'RRN
"N'))"N)"
6
simultaneous$N$"N'."-N?
?)H$N"N
"-NI))" N(
<))$"
)$I)6
"'$$$(2
)6)6(!0:
$) observaonal method $
)$)$$(
%)"$)"'
)()"""0MY
N"<2H''$$
)(
E6"$5"#$
)(
Results:
A$50 cases "
$'')$$$'(
0#7$$M'
6N(
 M5N"'5(!#H
M$-!N(
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HM$ - N' ((
17 "1Z*:"3Z"3Z2"3(MN(%
6)(01("?(95(
0$$)'+M#N"<M N"EM N"6
M N"DM-N"M-N"0M-N"0MN"M"')
:)*N"<:MN"<MN""E"
E"2"+(
0$$)
6)M$7&N(%
$"$ "'$
(-(
0'))B'H='"
)$$=$$
(
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)'"
9
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M5)NH<VM)NH%M5)NH%)M5
)NH;$M )NH<M-)NH6)B
M-)NH1M-)NH*M-)NH,(M
)NHFM)NH3M)NH+"
I"*"*"<"*"K
"2")"0"*"
)MN(
D'(%$)
)$6(
All paents were symptomac and classied as COVID posive or highly probable; they were all
treated homeopathically in extra-hospital home isolaon regimen.
Under no circumstances, given the favourable clinical trend, was hospitalisaon necessary.
A'
:)(
Discussion and perspecves
06.
$U)(
0"'
$(
18 K7E,
A6')
)(0$$)
)))'
interconnecon between paent and doctor$)(E
76"
$online medical consultaon,)
(
,'.)$$)"'
))T(0)$
$(
0hospitalizaon rate $#)$'(
3)$)7
"'')7'
)(
+"'.'"7:)
$))'7"(())
)")")'
(
0$:)$))"$
M( Q"0.K"N(
Aessenal to collect data on the level of hospitalizaon and clinical course of all
paents in home isolaon for COVID-19.
0.$))"'')$
"$$').
D0)'')")"
)
“The clinical manifestaons of COVID-19 are protean, which include asymptomac carrier, ARD,
and pneumonia of varying degrees of severity. First, asymptomac cases were diagnosed based on
posive viral nucleic acid test results, but without any COVID-19 symptoms, such as fever,
gastrointesnal, or respiratory symptoms, and no signi'cant abnormalies on chest radiograph,
19 ;"13+"E*E(K))(<);(
H9M-N#5((5?I(((( (;K5(<+<+-!!P R)R"
7)$)))$$"
$')))")$7)"
'")')C
20 *A*"/F"DE[2"*2"E.(+
)%+G,L(K
F( HMN ((#?-#9#(; K!(<+<+ 5-55
21 1"1\,"A\"A\,",*"\+\"FA",<2(%)"
"M*%2*NK
(/+$(+ (*59 9MN- (
(5?I(I((((W;$X2'(<+<+-!- H<+<+
<+!9#
However, the transmission of COVID-19 through asymptomac carriers via person-to-person
contact was observed in many reports. Second, paents with ARD de'ned as laboratory-con'rmed
COVID-19 cases had respiratory symptoms; however, chest computed tomography (CT) did not
reveal signs of pneumonia. Third, paents with pneumonia de'ned as COVID-19 cases had both
respiratory symptoms and pneumonia on chest radiograph.
%$diagnosc integraon of the
$6)(
8$)$I)M
-N))(0""$
)6"$
$)(
A much larger sample$)>U
$Hcontrol group must(
'long-term follow-upM)N$
""'.'
)(
,'"$")$)
$(077")
)$U"
)$')
R0)$')$0+'
"$"
R(
22 YL"K1"L,"1/F"A%+",\",Y"\E"A/"1,"]/"1+"1\*"1A/",<"
1A,(W))$$X(L\
YLL(+HMN;((-!5?(I(-!9 (W;$X
(<+<+-#!9 (
23 Chen X, Ling J, Mo P, Zhang Y, Jiang Q, Ma Z, Cao Q, Hu W, Zou S, Chen L, Yao L. Restoration of
leukomonocyte counts is associated with viral clearance in COVID-19 hospitalized patients. medRxiv. 2020 Jan 1.
https://scholar.google.com/scholar?
hl=en&as_sdt=0%2C5&q=Restoration+of+leukomonocyte+counts+is+associated+with+viral+clearance+in+COVI
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... Under no circumstances, because of good clinical practice, hospitalization was required. The hospitalization rate in this group of 50 patients treated homeopathically for COVID-19 was Zero (0) (Valeri, 2020). ...
... In Cuba, homeopathic medicine is an integral part of health care and was incorporated into the National Health System in 1992. At the beginning of the Covid-19 epidemic, in early April 2020, (Valeri, 2020). ...
Article
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Among the seven human coronaviruses (HCoVs), SARS, MERS, and SARS-CoV2 caused the most severe illnesses. Although WHO recommended three vaccines against Covid-19, this does not guarantee complete protection against the human body. Since the virus constantly changes and infects people causing great suffering and death, we must protect ourselves by following specific hygiene rules. This study showed the effectiveness of Homeopathic Remedies as the alternative treatment for Covid-19. Samples (suspected and confirmed patients of Covid-19) were given homeopathic medicines, and the results were recorded. This study aims to demonstrate a global effort to control the coronavirus (COVID-19) through alternative therapies. National health systems should promptly endorse the efficacy of validated homeopathic treatments to treat the Covid-19 disease as alternative medicine.
... The analysis of three variants of KAP was done after adjusting the values. Total KAP score was used to rank the level of knowledge and subsequent analysis was conducted to rank fair (0-10) and very good knowledge (11)(12) on the basis of median score. Association of demographics and level of knowledge was done using logistics regression. ...
... Since the majority of the respondents disagreed with the fact that COVID-19 can be treated with antibiotics and also acknowledged that early symptomatic and supportive treatment can help most patients recover, they could be looking for a possible integrated approach to combating it. 12 Due to the imposed lockdown, the study was restricted in the manner to which it could be distributed. The limitation of this study was that the sample was overrepresentative of white women, largely living in Gauteng province in South Africa. ...
Article
Full-text available
Background: The novel coronavirus (COVID-19) pandemic has spread rapidly inviting unprecedented measures globally. Citizen’s adherence to jurisdiction is affected by their knowledge, attitudes, and practices (KAP) towards the disease.Methods: A cross-sectional survey study among a convenient sample of the general public aged 18 years or more and resident in South Africa was conducted through a self-designed online KAP survey questionnaire during the first few weeks of the South African lockdown to assess the knowledge, attitudes and practices about COVID-19. A p value of <0.05 (two tailed) was taken to be statistically significant.Results: A total of 885 respondents completed the survey, majority of which were females who identified COVID-19 as a challenge to health and society and agreed with the strategy of lockdown for initial control of the spreading epidemic. In spite of the high knowledge scores of the population 31% of the respondents did not choose to wear a mask while leaving home. Also, a large number of respondents believed that early symptomatic treatment can prove useful to manage the infection. A statistically significant p value (<0.05) was obtained for the study variables in the statistical analysis, which showed that high knowledge scores were found to be associated with gender, categories of annual income and ethnicity.Conclusions: This survey shows that South African residents of a relatively high level of socioeconomic status, in particular women, have substantial knowledge, positive attitudes, but need to improve practices towards COVID-19 during the rapid rise phase of the COVID-19 outbreak.
... In our study, we found that Arsenicum album, Phosphorus, and Bryonia were the most prescribed medicines. It corroborated with the findings of physicians of Italy [23], though not a systematic study. Similar findings were reported by Michael et al. [24] regarding useful remedies. ...
Article
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Highlights • A randomized, placebo-controlled trial of adjunct homeopathy with standard of care for COVID-19 was conducted on 300 patients. • Primary outcome on total symptom score measured over 10 days decreased significantly favoring Standard of care + Homeopathy. • Recovery was earlier in Standard of care + Homeopathy group by 02 days showing the added benefits of homeopathy. • Resolution of fever was 20 h earlier in Standard of care + Homeopathy. • Arsenicum album, Bryonia alba and Phosphorus were the most frequently prescribed medicines. Visit article http://dx.doi.org/10.1016/j.ctcp.2022.101602
... In the current outbreak of COVID-19 in Iran, a group of patients' were treated with homeopathic medicines [160]. Another study was done in Italy in which a group of patients probable and positive of COVID-19 was treated with homeopathic medicines [161]. Based on the results of these studies, homeopathic medicines are suggested for the prevention and treatment of COVID-19 infection [154]. ...
Chapter
The ongoing outbreak of coronavirus-19 (COVID-19) has quickly become a daunting challenge to global health. The ultraviolet radiations (UVR) A wavebands fall in the region of 320-400 nm of the solar spectrum and comprise about 95% of overall ultraviolet (UVs) approaching the biosphere. The UVA is extensively used in phototherapy systems, as a disinfectant, and in various skin-related conditions. This chapter aimed to address the reduction of coronavirus replication by direct application of phototherapy (UVA) in lungs and modulation of nitric oxide (NO) in skin cells following UVA exposures. This NO influx inside the bloodstream to deliver into the lungs endothelial cells where it goes to incur cytoprotection to alveolar lung cells. Moreover, it is also proposed for direct application of therapeutic doses of UVA light inside the lungs. It uses a fiberoptic adapter to modulate the production of NO in lung endothelial cells, which will diffuse into the bronchi and lungs to leave bronchodilatory and vasodilatory effects. How NO reduces inflammatory burst and reactive oxygen species (ROS) in the lungs' alveolar cells is also discussed. Moreover, it is also proposed that UVA radiation application should be limited to physiological doses and applied every 4-8 h, with at least 24 h of therapy before reassessment. The treating physician should determine discontinuation of this direct UVA treatment into the lungs following observation of the patient's condition and the safety and efficacy of the treatment. This study will highlight and emphasize the importance of utilizing UVA radiation to control this epidemic.
... In the current outbreak of COVID-19 in Iran, a group of patients' were treated with homeopathic medicines [160]. Another study was done in Italy in which a group of patients probable and positive of COVID-19 was treated with homeopathic medicines [161]. Based on the results of these studies, homeopathic medicines are suggested for the prevention and treatment of COVID-19 infection [154]. ...
Chapter
Full-text available
Coronavirus disease-2019 (COVID-19) first originated from China, named Wuhan, and now becomes a pandemic disease. The COVID-19 infections range from asymptomatic to mild and severe conditions. Medicinal plants have potential therapeutic effects for different infectious diseases and have long been used to treat many diseases. Wild plants are well-known for their anti-viral activities and are also used in herbal treatment for COVID-19 infection. Various traditional medicine systems use plants for the treatment of COVID-19. The considerable therapeutic effect was achieved by using traditional Chinese medicine (TCM) during the 2003 outbreak of severe acute respiratory syndrome (SARS), which brought new hope preventing and treating COVID-19. The Ministry of Ayurveda, Yoga & Naturopathy, Unani, Siddha, and Homoeopathy (AYUSH) focuses on prophylactic treatment, dietary management, and simple traditional remedies for the treatment of symptoms of COVID-19 by using medicinal plants. Telemedicine was focused on a new health care model to prevent transmission of COVID-19 by avoiding person-to-person contact. The purpose of this chapter is to identify the effective herbal treatment for COVID-19.
... In the current outbreak of COVID-19 in Iran, a group of patients' were treated with homeopathic medicines [160]. Another study was done in Italy in which a group of patients probable and positive of COVID-19 was treated with homeopathic medicines [161]. Based on the results of these studies, homeopathic medicines are suggested for the prevention and treatment of COVID-19 infection [154]. ...
Chapter
Full-text available
The recent emergent coronaviruses in the 21st century, such as Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV), Middle East Respiratory SyndromeCoronavirus (MERS-CoV), and severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has caused significant morbidity and mortality around the world. The lung is the most affected organ in the infection of human pathogenic coronaviruses. There is always a scarcity of human signs, symptoms, and modes of transmission. So to study the viral pathogenesis and evaluated interventions of therapies and vaccines, animals need to be used as models, especially at early epidemics. Lesions scoring can be identified from histopathological studies, and it can be helpful to understand the viral pathogenesis and damages to the cells to design effective therapies or vaccines. Histopathology uses the cells to determine viral host receptors and viral host tropism to relate with disease severity and lesions. Moreover, histopathology also plays a role in the qualitative description of affected organs to determine the micro-anatomic location of cells, type of cells, and cellular consequences during and post-infection. Comparatively, this approach has various limitations, but still, it is significant in comparing treatment groups. In comparing various groups, semi-quantitative and quantitative tissue scores are used for statistical analysis to increase the reproducibility of the study. This chapter refers to different features, including the importance of histopathology, principles, technique, scoring methods, and pathological characteristics of COVID-19, which can be valuable to assess the lung infection caused by SARSCoV-2 and animal models and real situations.
... Patients treated with Bryonia Alba 30C recovered 20% in the first 12 hours and 70-95 percent on day 3, patients treated with Gelsemium sempervirens 30C recovered 20-50 percent in the first 12 hours and 70-100 percent on day 3, patients treated with Arsenicum album 30C recovered 50% in the first 12 hours and 100% on day 3, and patients treated with Eupatoriu 30C recovered 50% in the first 12 hours and 100% on day 3. [189]. In Italy, 50 patients were treated with medicines namely Arsenicum Album, Phosphorus Flavus, Atropa Belladonna, Antimonium Tartaricum, Eupatorium Perfoliatum, Hepar Sulphur, Lycopodium Clavatum, Kalium Phosphoricum which showed overall recovery and no patients were needed to be hospitalized during the recovery period [190]. Despite the fact that many homoeopathic medicines showed promising results in COVID-19 patients, this branch of medicine is understudied in terms of efficacy and needs further research. ...
Article
Coronavirus Disease 2019 (COVID-19) manifests as extreme acute respiratory conditions caused by a novel beta coronavirus named severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) which is reported to be the seventh coronavirus to infect humans. Like other SARS-CoVs it has a large positive-stranded RNA genome. But, specific furin site in the spike protein, mutation prone and phylogenetically mess open reading frame1ab (Orf1ab) separates SARS-CoV-2 from other RNA viruses. Since the outbreak (February - March 2020), researchers, scientists, and medical professionals are inspecting all possible facts from every possible aspect including its replication, detection, and prevention strategies. This led to the prompt identification of its basic biology, genome characterization, structural and expression based functional information of proteins, and utilization of this information in optimizing strategies to prevent its spread. This review summarizes the recent updates on the basic molecular biology of SARS-CoV-2 and prevention strategies undertaken worldwide to tackle COVID-19. This recent information can be implemented for the development and designing of therapeutics against SARS-CoV-2.
... For the convalescence phase, he has suggested Kali carbonicum or Opium with positive effect. Andrea Valeri [19] , Italy, reported 50 symptomatic cases of COVID-19 treated with Homoeopathy. In her cases, all the patients are in home isolation and diagnosed positive or probable COVID-19. ...
Article
Full-text available
Corona virus disease or COVID-19 is a viral disease caused by SARS-CoV-2 and declared pandemic by WHO. The COVID-19 infection has emerged from Wuhan, China in late December of 2019 and soon become a global health emergency spreading over 216 countries and territories around the world as there are no specific established treatments or vaccines available till date. Scientists around the world are constantly enganged in research work to find out specific treatment and vaccines for this disease. Several cases of treatment are being reported by the Homoeopathic physicians all over the world and the results are promising. Some of the Homoeopathic medicine which are being used with good results are Bryonia alba, Phosphorus, Arsenic album, Gelsemium sempervirens and Carboneum oxygenisatum. Ministry of AYUSH, Government of India has recommended the Homoeopathic medicine Arsenic album 30 as an immune booster for its possible role in preventing COVID-19 infection, and results are slowly coming out in the favour of this medicine. Homoeopathy as an adjuvant to the standard care should be evaluated for the management of COVID-19.
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Covid-19, özellikle solunum sistemi başta olmak üzere tüm vücut sistemini olumsuz etkileyen bir patojendir. Kısa sürede kontrolsüzce artan bu yeni tip koronavirüs salgını, dünya genelinde hızla artan bir yayılım göstermesiyle pandemi olarak ilân edilmiştir. Koronavirüs belirti ve bulguları, diğer viral üst solunum yolu enfeksiyonlarının belirtilerine benzemektedir. Semptomların şiddeti ise hastanın immün sisteminin durumuna, yaşına ve başka kronik rahatsızlıkların varlığına bağlı olarak değişkenlik göstermektedir. Bu salgının henüz kanıtlanabilmiş tedavisinin olmaması, araştırma gruplarını dünya çapında zorlamıştır ve içlerinde homeopatinin de yer aldığı geleneksel ve tamamlayıcı tıp uygulamalarına yönelimi başlatmıştır. Tarih boyunca Dang Humması, Chikungunya ateşi, İspanyol gribi ve sıtma gibi birçok salgın ve bakteriyel/viral hastalıkta homeopatik remedilerden faydalanılmıştır. Bu remedilerin seçiminde, patognomonik (hastalığa özgü) semptomlardan ziyade homeopatik semptomlar dikkate alınmıştır. Doğal ve bütüncül bir iyileştirme yöntemi olan homeopati; koronavirüsün tedavisinde de birçok ülkede kullanılmaya başlanmıştır ve olguların çoğunluğunda yüksek başarı elde edilerek semptomların büyük oranda ortadan kalktığı, hatta bazı olgularda semptomların tamamen yok olduğu saptanmıştır. Ancak bu semptomlar, her hasta için farklılık gösterebilmesi nedeni ile uygun remedinin tespit edilmesi için hastayı bütüncül değerlendirmek gerekmektedir. Salgın durumlarında Genius Epi-demicus; salgın hastalıkla ilişkili ortak semptomlar belirlenerek kişinin semptomlarına göre homeopatik remedi belirlenir. Makalede, yapılan çalışmalar doğrultusunda Covid-19'un semptomlarına yönelik kullanılabilecek olan remedilerin bazıları sunulmuştur. Bu doğrultuda; Covid-19 tanısı almış hastalarda, ayrıntılı anamnez alınarak homeopatik semptomlar tespit edilip bu semptomlara özgü homeopatik remediler kullanılabilir.
Article
As at mid-October 2020, the coronavirus disease 2019 (COVID-19) pandemic has been continuing on the rise across the globe, including in India. Historically, homeopathy has been used in a number of epidemics/pandemics. The development of homeopathic medicines is approached uniquely through “drug provings” and clinical verification; these two intrinsic processes establish the background for the application of homeopathic medicines, regardless of nosological diagnosis. This article reflects research initiatives on COVID-19 in India and identifies studies listed in the Clinical Trial Registry–India database. We identified 29 studies being undertaken in different settings, including those in conventional medicine: 20 randomized controlled trials (RCTs) and 9 observational studies. Fifteen studies are aimed at prophylaxis and 14 are aimed at treatment. Amongst the treatment studies, 11 are focused on efficacy or comparative effectiveness. The findings might provide evidence for clinically repurposing some of homeopathy's medicines, an approach that is intrinsic to the therapy, enabling their use in COVID-19 as an adjuvant or stand-alone to help reduce costs and improve patient recovery.
Objective: To construct and evaluate a diagnosis process for 2019-Corona Virus Disease (COVID-19). Methods: A continuous cohort of adults and adolescent (≥12 years) who screened COVID-19 was included in Xiangya Hospital of Central South University from January 23 to February 3, 2020 in which cases were divided the test library and the verification library. Their gender, age, onset time were recorded. Take epidemiological history, fever, and the blood lymphocytes decline as clinical indicators, used CT to evaluate the possibility of COVID-19 and range of lung involvement. According to the current national standards, throat swabs of suspected cases were collected and the nucleic acid of COVID-19 was detected by reverse transcription-polymerase chain reaction (RT-PCR). The Xiangya process was constructed according to multi-index, compared with clinical indicators, CT results and national standards, the efficiency of detecting confirmed cases were verified in the test and verification library. Results: A continuous cohort of 382 adults who screened COVID-19 was included in which 261 cases were in the test library and 121 cases were in the verification library. In the 382 cases, 192 were males (50.3%) and 190 were females (49.7%), with a median age of 35 years (range: 15-92 years). There were 183 cases (47.9%) with epidemiological history, 275 cases (72.0%) with fever, 212 cases (55.5%) with decreased hemolytic lymphocytes, CT positive 114 cases (29.8%), 43 cases (11.3%) with positive CT-COVID-19, and 30 cases (7.9%) with positive throat swab nucleic acid. Compared with clinical indicators, the sensitivity and specificity of CT were 0.950 and 0.704, respectively. The accuracy of CT to make a definite diagnosis was higher than that of epidemiological history, fever, and blood lymph count decline (0.809 vs 0.660, 0.532, 0.596, P=0.001, 0.002, 0.003, respectively). The sensitivity of this process and the program recommended by the Health Commission all were high (all were 1.000) , and the specificity and accuracy of the process were higher than the program recommended by the Health Commission (0.872 vs 0.765, 0.778 vs 0.592, both P<0.001). The CT-COVID-19 would have reduced the missed diagnosis rate caused by false negative of nucleic acid test (31 vs 64, difference rate 51.6%), the positive rate of nucleic acid test was 64.5% (20/31). In validation library, the specificity and accuracy of the Xiangya process was 0.967, the positive rate of nucleic acid test was 76.9% (10/13). Conclusions: The Xiangya process can predict the nucleic acid test results of COVID-19 well, and can be applied as a reliable basis for confirmed cases detection in adults and adolescent (≥12 years) in areas other than Hubei during the epidemic period of COVID-19. The cohort size needs to be increased for further validation.
Restoration of leukomonocyte counts is associated with viral clearance in COVID-19 hospitalized patients. medRxiv
  • X Chen
  • J Ling
  • P Mo
  • Y Zhang
  • Q Jiang
  • Z Ma
  • Q Cao
  • W Hu
  • S Zou
  • L Chen
  • L Yao
Chen X, Ling J, Mo P, Zhang Y, Jiang Q, Ma Z, Cao Q, Hu W, Zou S, Chen L, Yao L. Restoration of leukomonocyte counts is associated with viral clearance in COVID-19 hospitalized patients. medRxiv. 2020 Jan 1. https://scholar.google.com/scholar? hl=en&as_sdt=0%2C5&q=Restoration+of+leukomonocyte+counts+is+associated+with+viral+clearance+in+COVI D-19+hospitalized+patients.+&btnG=