PosterPDF Available

Jerusalem artichoke effects on Blood glucose and TG level in male diabetic rats

Authors:

Abstract

Jerusalem artichoke effects on Blood glucose and TG level in male diabetic rats Introduction: Jerusalem artichoke (Helianthus tuberosus) is a species of sunflower with a lumpy brown tuber that resembles ginger root. Iranian herbal medicine has mentioned antiglycemic and antilipidemic effects for Jerusalem artichoke. The objective of this study was to examine this hypothesis. Materials and methods: 20 Samples were chosen from male rats (220–250 gr). Rats were randomly devided to 2 groups. All 20 rats, were fasted for 12 hours before an intramuscular injection of streptozotocin 50 mg/kg. Two days after STZ injection, the rats were considered diabetic. The control group rats fed with 1 mL of physiologic saline daily, for 3 weeks. The case group rats fed with Jerusalem artichoke solution 100 mg/kg daily, for 3 weeks. Plasma glucose and TG level were measured before and at the end of the test Results: The body weight gain, pancreas and liver weights were similar in both groups; but water and food intakes were lower in case group (P value< 0.05). Intaking of Jerusalem artichoke reduced plasma glucose significantly compared with control diabetic rats(P value< 0.05); However there was no significant diffrence in Plasma TG level between 2 groups. Discussion: This study showed that using of Jerusalem artichoke can reduce plasma glucose level in diabetic rats; Howe ever it has no effect on plasma TG level. More studies are suggested to find its action mechanism on reducing plasma glucose level.
Jerusalem artichoke effects on Blood glucose and TG level in male
diabetic rats
Introduction: Jerusalem artichoke (Helianthus tuberosus) is a species of sunflower
with a lumpy brown tuber that resembles ginger root. Iranian herbal medicine has
mentioned antiglycemic and antilipidemic effects for Jerusalem artichoke. The
objective of this study was to examine this hypothesis.
Materials and methods: 20 Samples were chosen from male rats (220–250 gr).
Rats were randomly devided to 2 groups. All 20 rats, were fasted for 12 hours
before an intramuscular injection of streptozotocin 50 mg/kg. Two days after STZ
injection, the rats were considered diabetic. The control group rats fed with 1 mL
of physiologic saline daily, for 3 weeks. The case group rats fed with Jerusalem
artichoke solution 100 mg/kg daily, for 3 weeks. Plasma glucose and TG level
were measured before and at the end of the test
Results: The body weight gain, pancreas and liver weights were similar in both
groups; but water and food intakes were lower in case group (P value< 0.05).
Intaking of Jerusalem artichoke reduced plasma glucose significantly compared
with control diabetic rats(P value< 0.05); However there was no significant
diffrence in Plasma TG level between 2 groups.
Discussion: This study showed that using of Jerusalem artichoke can reduce
plasma glucose level in diabetic rats; Howe ever it has no effect on plasma TG
level. More studies are suggested to find its action mechanism on reducing plasma
glucose level.
ResearchGate has not been able to resolve any citations for this publication.
ResearchGate has not been able to resolve any references for this publication.