Conference Paper

The Daphne Traditional Use and Biological Activities

September 2019

Conference: ECOMB 2019
At: Trabzon, Turkey

Authors:

Djillali Liabes University Sidi Bel Abbès

Université d'Oran 1 AHMED BENBALLA

Benhaddou Abdelhak Ismail

Djillali Liabes University Sidi Bel Abbès

Mohamed Yacine Achouri

Djillali Liabes University Sidi Bel Abbès

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In vitro antimitotic activity of gall extract of Pistacia terebinthus

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Dec 2020

Pistacia terebinthus L. - turpentine tree - is a perennial flowering plant in the Mediterranean region, some aphids species induce the formation of galls in Pistacia terebinthus formerly called Carobs of Judea whose tannin content equals 60%, used in traditional medicine as a stimulant, diuretic, astringent for the treatment of asthma and other respiratory and urological affections. In the present study, the antimitotic activity of Pistacia terebinthus galls was evaluated using meristematic cells of Allium cepa roots assay our results reveal that the methanolic extract decreased the root length and dividing cell number significantly after 96 h and compared to control (p< 0.05) the mitotic index of extract at the concentration 4 mg/ml was 31% and has significant activity near to the standard methotrexate. Overall, the methanol extract of P. terebinthus galls revealed the presence of the phytochemical’s compounds such as gallic acid, caffeoylquinic acid, which affect plant mitosis and can be used as an antimitotic drug.

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Trichilia emetica, a plant native to Africa, is used in traditional medicine to treat various ailments such as abdominal pains, dermatitis, haemorrhoids, jaundice and chest pain. This species also known as Natal Mahogany is used for its emetic, diuretic and purgative properties and for induction of labour. The extensive traditional use of this species has encouraged scientists to explore several ... [Show full abstract] biological activities including anti-infective, anti-inflammatory, antischistosomal, antiplasmodial, anticonvulsant, antitrypanosomal, anti-oxidant, antitussive, antimutagenic and hepatoprotective properties. Several limonoids have been isolated from the stem bark. Trichilia substance Tr-B and nymania 1 exhibited selective inhibitory activity towards DNA repair-deficient yeast mutants and exerted antifungal, bactericidal, antiviral, antifeedant and growth regulating properties. Polysaccharides have been isolated and the pectin rhamnogalacturonan type I with side chains of arabinogalactan type II exhibited fixation ability suggesting the possible mode of action as a wound healing remedy. This review aims to coherently unite results obtained from various studies on this ethnomedicinally important species.

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Aronia Plants: A Review of Traditional Use, Biological Activities, and Perspectives for Modern Medic...

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The Aronia genus (Rosaceae family, Maloideae subfamily) includes two species of native North American shrubs: Aronia melanocarpa (Michx.) Ell. (black chokeberry) and Aronia arbutifolia (L.) Pers. (red chokeberry). The fruits of A. melanocarpa have been traditionally used by Potawatomi Native Americans to cure colds. In the first half of the 20(th) century, cultivars of black chokeberry were ... [Show full abstract] introduced to the Soviet Union and other European countries, providing fruits used by food industry. At present, it is used mainly for juice, jam, and wine production, as well as an ornamental plant. Among other substances, the berries of A. melanocarpa contain anthocyanins and procyanidins, possessing strong antioxidative potential. Numerous health-promoting activities-namely, antioxidative, antimutagenic, anticancer, cardioprotective, hepatoprotective, gastroprotective, antidiabetic, anti-inflammatory, antibacterial, antiviral, radioprotective, and immunomodulatory-have been demonstrated for black chokeberry extracts by both in vitro and in in vivo studies. The presented review summarizes the information concerning botany, cultivation, chemical composition, and pharmacological activities of Aronia plants.

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This work aims to study cultivable actinobacterial isolated from the rhizosphere soil of Artemisia herba-alba Asso; an important component of the Mediterranean dry steppe flora. The isolates functional attributes with respect to antifungal, in vitro growth-promotion properties and enzymatic capacities, were studied. A total of eleven cultivable actinobacterial strains were isolated and identified ... [Show full abstract] as Streptomyces species by 16S rRNA gene sequencing. The eleven Streptomyces strains were positive for the production of almost all the hydrolytic enzymes tested, while the majority had ACC deaminase activity (6 strains) and exhibited ammonia (7 strains), siderophores production (9 strains) and phosphate solubilization (6 strains). Two out of the eleven strains named Streptomyces sp. BKS30 and BKS40 showed antifungal activities. One promising Streptomyces sp. strain BKS30 that was in-depth characterized morphologically and biochemically was further tested for its antifungal activity for the filtrate and the butanolic extract against nine target-fungi as well as for its antioxidant activity by DPPH and ABST tests. The obtained results demonstrate that Streptomyces species isolated from the rhizosphere of Artemisia herba-alba Asso have the potential for different biological activities including antifungal and antioxidant activities particularly for strain BKS30.

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Rumex abyssinicus is a valuable medicinal plant species that is native to tropical Africa. Traditionally, R. abyssinicus is used to treat different disease such as, liver diseases, hepatitis, malaria, scabies, blood pressure, jaundice, wound and pneumonia. The purpose of the current study was to review the literature on the ethnomedicinal uses, chemical constitutes and biological activities of R. ... [Show full abstract] abyssinicus in an attempt to create information for future studies aimed towards exploring the therapeutic ability of the species. A scientific search engines, namely Google Scholar, PubMed, Scopus, Science Direct and Web of knowledge for the search terms: Rumex abyssinicus, ethnomedicinal studies, phytochemical investigations, and pharmacological activities were undertaken. The search strategy included all articles with descriptors that were available until December 30, 2021. Only published works in English have been used on this study. The data was collected using textual descriptions of the studies, tabulation, grouping, and figures. The principal phytochemicals of R. abyssinicus are anthraquinones, flavonoids, terepenoids and phenolic compounds. The in vitro and in vivo studies on the crude extracts and compounds of R. abyssinicus showed antibacterial, antioxidant, anticancer, anti-inflammatory, antifungal, wound healing, antialzeimer’s and hepatoprotective activities of it. R. abyssinicus afforded drug leads such as helminthosporin (4) with anti-alzheimer and physicon (3) with antifungal and antioxidant activity. R. abyssinicus have traditionally been used to cure a variety of diseases. Pharmacological actions of phytochemicals were shown to be promising. Despite this, further studies on crude extracts and promising compounds are needed to find new drug candidates.