Mobile Base Program for Drug-Drug Interactions (MBPDDIs)

Abstract

Abstract: A mobile application program was used in performing a drug-drug interactions (DDIs) for drugs used in Iraq, depending on the drug-drug interactions chart (DDIsC) originated by Ninava Drug Industry (NDI). Two programs were used for designing this work; the first is Microsoft office access which is used to design the form which included the list of drugs and ten registers under it contain different drugs names (Access of drug was available through browsing therapeutic groups or searching for a brand name). If the drug in combo list interacts with more than ten drugs, the combo contains the same name of drug but with number 2, 3 and so on.
The design which includes in mobile contains android system.
In the second design of the drugs interaction a visual basic program is used. Two lists of drugs were used in this program. When a drug from the first list is selected with another drug from the second list, the symbol offer at text box.

Full text

Engineering and Technology Journal Vol. 35, Part B, No. 1, 2017
Copyright © 2017 by UOT, IRAQ 63
N. L. Mohammed
Dept. of Computer
Eng. Technical College
Mosul. Iraq
nakaa_alhamo@yahoo.com
Sh. M. Saied
Dept. of Pharmacy
Institute of Technical
Mosul. Iraq
shakirmsaied@yahoo.com
A. H. Maray
Dept. of Computer System
Institute of Technical
Mosul. Iraq
Received on: 27/02/2014
Accepted on: 20/07/2014
Mobile Base Program for
Drug-Drug Interactions (MBPDDIs)
Abstract: A mobile application program was used in performing a drug-drug
interactions

(DDIs) for drugs used in Iraq, depending on the drug-drug interactions
chart

(DDIsC) originated by Ninava Drug Industry

(NDI).

Two programs were used
for designing this work; the first is Microsoft office access which is used to design
the form which included the list of drugs and ten registers under it contain different
drugs names

(Access of drug was available through browsing therapeutic groups or
searching for a brand name). If the drug in combo list interacts with more than ten
drugs, the combo contains the same name of drug but with number 2, 3 and so on.

The design which includes in mobile contains android system.
In the second design of the drugs interaction a visual basic program is used. Two
lists of drugs were used in this program. When a drug from the first list is selected
with another drug from the second list, the symbol offer at text box.
Keywords: Mobile apps, Drug-Drug Interactions

(DDIs), Android system, Visual
basic, Microsoft access, Drug-drug interactions chart

(DDIsC).
How to cite this article N. L. Mohammed, Sh. M. Saied and A. H. Maray, “Mobile Base Program for Drug-Drug
Interactions (MBPDDIs),” Engineering and Technology Journal, Vol. 35, Part B, No. 1, pp. 63-67, 2017.
1.Introduction
A mobile application or “mobile app” is defined as
a software application that can be executed (run)
on a mobile platform ( a handheld commercial off-
the shelf computing platform, with or without
wireless connectivity), or a web-based software
application that is tailored to a mobile platform but
is executed on a server [1,2].
Mobile apps were applied and developed by
computer scientists in addition to doctors and
pharmacists whom they used these applications in
addition to ordinary peoples or patients[3-7]
At 2011, the potential of mobile health (m-
health) technologies for improving management
of Diabetes patients in southern Iraq was
evaluated and established a collaboration
framework with UK academic and diabetic
specialists [5-8]. Two years after this study, a
program of improving diabetes management with
mobile health technology was published in South
Carolina[8,9].
Recently, the problem of the effect of the
aneurysm and stenosis on the human blood stream
has been solved numerically under conditions in
Iraq[10,11].
Because mobile is becoming the preferred
consumer channel for communication, and for
pharmacists, mobile applications are a way to
better use of medications, thereby improving
healthcare results and owering costs, this research
(Drug-Drug Interactions Mobile Program
(DDIsMP) allows to put many drugs and its
interactions in pharmacists’ hands[12].
2. Motivation
Drug-drug interaction (DDIs ) could help doctors
and pharmacists whom they used these
applications in addition to ordinary peoples or
patients[13]. This work showed pharmaceutical
educational sessions through phone
3.Drug-Drug Interactions Mobile Program
(DDIsMP)
DDIs can be defined as a pharmacological or
clinical response to the administration of a drug
combination, different from that of anticipated one
from the known effects of the two agents when
given alone. The clinical result of a DDI may be
manifested as antagonism, synergism or
idiosyncratic[14,15].
4.Case Study
Data containing the (DDIs) chart originated by
Ninavah Drug Industries(NDI) was shown in
Figure 1.

Engineering and Technology Journal Vol. 35, Part B, No. 1, 2017

Figure1: Ninavah Drug-Drug Interaction Chart
5.Programming
A mobile app program was intended for use in
performing a drug-drug interactions(DDIs) for
drugs used in Iraq, depending on the (DDIs) chart
originated by Ninava Drug Industry(NDI).
Figure2: Access form of DDIs
1: Represent the list of drugs called combo list(list
of values from which the user can select a single
value)
2: Represent the symbols of interaction of each
drug with other(s).
If the drug in combo list interacts with more than
ten drugs, the combo contains the same name of
drug but with number 2, 3 and so on. At access
program there is selection called report. Reports
allow you to view and present data from your
database in a printed form. Access offers several
styles and formats for repots, so you can create a
customized document to suit your needs. So this
form has button called help, this button when
press it offers the report of the operation of the
symbols which used for interaction between two
different drugs as shown in Figure(3).
Figure 3: Report of drugs
The design which includes in mobile contains
android system, at beginning, three programs must
setup into mobile.
While the OfficeSuite_Pro_v5.1.515.apk is the
first, the Office quick q412.apk and
Database_0.3.4.apk were the second and third
respectively as shown in Figure 4 (a, b and c).
2
1

Engineering and Technology Journal Vol. 35, Part B, No. 1, 2017

(a) Quick Office (b) Database (c) Office Suit
Figure 4:The Installed Program at Mobile
Figure.(5) : The form at mobile
Figure.(6) : The form at mobile
Noting that the designing access programs were
stored in mobile. The form of program in mobile is
shown in Figures (5 and 6).At the list beside the
search of column the name is selected , while at the
list beside the search for value the name of drug is
written, then the list of interaction drugs will be
appear after press the enter icon as shown in Figure
(5 and 6).At the row of name, the drug which need
to know it's interactions with other drugs is
written, then ok button is pressed, the list of drug
appear at the down of the drug's name and the
interactions symbol are at the right of the list with
one of their colors (black, blue or red). At this
figure we select the name of drug is
Metronidazole, so the list of drugs which interact
with it are Alcohol, Antacids, and Anticoagulants
and so on. The symbol (+↑) mean the interaction
effect enhanced at Metronidazole because the
arrow is up directed, at the fourth row the refer to
right with minus symbol which mean the effect
enhanced reduced in Barbiturates and so on for
other symbol which explain in Figure(2).The
second design of drugs interaction by using two
lists for drugs, when select one drug from the first
list and another drug from the second list the

Engineering and Technology Journal Vol. 35, Part B, No. 1, 2017

symbol offer at text box as shown in Figure(7). In
this picture the first drug which selected is one of
Anti-cholinergic and the second drug is
Barbiturates, when pressed at DDI icon then NI
appear at the square plane that is mean there is no
interactions between the selected drugs.
Figure.(7):Visual Basic Form
System Evaluation:
The program is considered to be m-health system
and practical, so the users can achieve the
interactions between the drugs easily. The usability
is important in m-health system .
Conclusion:
Mobile medical apps are rapidly becoming one of
the best significant apparatuses in clinical practice.
They are an effective and appropriate means to
provide real-time medical information at the
physicians and pharmacies.This program helps and
enables physicians, pharmacists and even a
patients to know about the DDIs which decrease
the risks of taken more than one type of drug.
Advances will continue to improve patient in
mobile technology Care and its knowledge's in the
medicines that he used.improve patient in mobile
technology Care and its knowledge's in the
medicines that he used.
Abbreviations:
app: application
DDIs: Drug-Drug Interactions
NDI: Ninavah Drug Industries
DDIsC: Drug-Drug Interactions Chart
FDA: Food and Drug Administration;
PHR: Personal Health Record
HER: Health Electronic Record
M-health: mobile health.
DDIsMP: Drug-Drug Interactions Mobile Program
NI: No Interaction
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Author(s) biography
Naqaa Luqman Mohammed, Assist. Lecturer, Msc.
in Computer Technical Engineering in 2012 , College
of Engineering Technical, North Technical
University, Mosul. Iraq
She has some publications research in different
place such as "Circuit Design and Implementation
of Dental System Controller Based on FPGA" in
Journal of Babylon University, "Controlling
Directivity of Solar Cells Array Based on FPGA"
in Al Altaqani Journal, "Circuit Design and
Implementation of 3-D Programmable Position
Controller Based on FPGA", in the 12th Scientifical
Conference Foundation of Technical Education.
Ass .Lec. Mohammed,work in Computer Technical
Engineering Dept./ Engineering Technical College
Shakir Mahmood Saied,
Assistant Professor of Organic
Chemistry, PhD Organic
Chemistry, Department of
Chemistry, College of Science
University of Mosul 2000 . MSc
from College of Pharmacy (Pharmaceutical
Chemistry) in 1983. The research interests are
Organic chemistry, Heterocyclic Chemistry and
pharmaceutical Chemistry, in addition to
Computational chemistry (more than 27 published
papers) . Assistant Prof. Saied is a member of
Royal Society Chemistry at 2011.
Assistant Professor
Dr. Shakir Mahmood Saied
Ph.D Organic Chemistry
MSC. Pharmaceutical Chemistry
Member of RSC
Dept.of Pharmacy Institute of Technical Mosul\
Iraq
Telephone : mobile) +9647701738333
Abdalrafi Hoseen Maray
Assistant Lecture, Msc. in
Computer Technical Engineering,
College of Engineering Technical.
Work in Department of computers
systems /Institute of north
technical university mosul. Iraq
Mobile:(009647702064046)