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Research Article
Comparing the Effect of Foot Massage with Grape Seed Oil and
Sweet Almond Oil on Physiological Leg Edema in Primigravidae:
A Randomized Clinical Trial
Maryam Navaee and Marzieh Rakhshkhorshid
Midwifery Department, Pregnancy Health Research Centre, Zahedan University of Medical Sciences, Zahedan, Iran
Correspondence should be addressed to Marzieh Rakhshkhorshid; marzieh.rakhshkhorshid@gmail.com
Received 8 May 2019; Revised 7 August 2019; Accepted 29 August 2019; Published 13 January 2020
Academic Editor: Shao-Hsuan Kao
Copyright ©2020 Maryam Navaee and Marzieh Rakhshkhorshid. is is an open access article distributed under the Creative
Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the
original work is properly cited.
Background. Leg edema is a prevalent problem in pregnancy causing activity restrictions for pregnant women. is study was
performed to compare the effect of foot massage using grape seed oil and sweet almond oil on physiological leg edema. Methods. A
randomized clinical trial was conducted on 90 primigravidae referred to public health centres of Zahedan, Iran. e participants’
gestational age was 30–40 weeks. e study was conducted from August 2016 to November 2017. e participants were randomly
assigned to three groups (massage with grape seed oil, massage with sweet almond oil, and without intervention). After de-
termining the extent of leg edema, foot massages were done for 20 minutes within 5 days in the two intervention groups. en,
foot circumferences were measured on day 5 after the intervention. Foot circumferences for the control group were measured on
days 1 and 5. A nonelastic tape measure was used to measure the circumferences. To analyse the data, SPSS 21 software and
statistical tests including one-way ANOVA, Tukey’s test, and paired t-test were used. Results. e results from this study showed a
significant difference in the mean score change of foot circumferences between groups (P�0.001). According to the results of
Tukey’s test, mean score changes of foot circumferences of both intervention groups were significantly different those of the
control group. However, this difference was not significant between the two intervention groups (P�0.865). Conclusion. e
findings of this study confirmed the effectiveness of foot massage using grape seed and sweet almond oils to reduce pregnancy
physiological edema. erefore, foot massage with appropriate oils can be used as a useful technique by trained midwives in
prenatal care centres or at pregnant women houses. is trial is registered with IRCT2015072723370N1.
1. Introduction
Anatomic and physiologic changes caused by pregnancy
result in an array of symptoms affecting the lower extremity
[1, 2]. e increasing weight of the growing uterus puts
pressure on pelvic veins and on the inferior vena. is in-
creases blood pressure in leg veins leading to venous in-
sufficiency and leg edema. Leg edema can affect up to 80% of
pregnant women and should not be considered a sign of
pregnancy-induced hypertension or preeclampsia [3]. e
most common symptom of edema is the experience of
substantial pain, as well as night cramps, numbness, and
tingling. In addition, legs may feel heavy and achy and
possibly be unsightly [4]. Symptoms tend to worsen after
long periods of standing and with each successive pregnancy
[3]. Since treatments to relieve common discomforts of
pregnancy such as edema should not threaten the mother
and fetus [5–7], many midwives and pregnant women seek
complementary therapies such as massage therapy [3, 8]. A
nonpharmacological intervention which is popular among
healthcare providers is foot massage [9]. e technique in leg
and foot edema works by moving extravascular fluid without
disturbing intravascular fluid [10], increasing peripheral
blood flow, boosting oxygen, and therefore reducing edema
[11].
Using oil during a massage helps the hands of a masseur
move easily on the skin and causes the skin to minimize
dryness [12]. Grape seed oil and sweet almond oil are used in
Hindawi
Evidence-Based Complementary and Alternative Medicine
Volume 2020, Article ID 6835814, 6 pages
https://doi.org/10.1155/2020/6835814
therapeutic massage [13]. ese oils are good sources of
essential fatty acids and vitamin E, polyphenols, and fla-
vonoids [14] and cause some type of improvement in var-
icose veins, hemorrhoids, and limb edema by improving
blood circulation. In addition to their anti-inflammatory
properties, they can be effective in relieving edema caused by
problems such as rheumatoid arthritis [15]. Sweet almond
oil contains vitamin E and riboflavonoids that, of course,
have little antioxidant effect [16]. However, its advantage
compared to grape seed oil is that it is cheaper and more
accessible [17, 18].
In general, studies on the effects of massage therapy on a
variety of healthcare settings have shown that this therapy
could be used as an effective treatment in a series of dis-
comforts while causing no damage [19]. Çoban and S
¸irin in
their study on the effect of foot massage with grape seed oil
on edema during pregnancy found significant results in
reducing edema and that the reduction was greater in the
right leg [20]. In a study conducted by Rahimikian et al. on
the effect of foot massage on physiological edema with baby
oil, significant results were seen in reducing edema [21].
Since, to our knowledge, few studies have examined the
effects of foot massage on edema resulting from pregnancy
and no studies have compared the results of using different
oils to select the best oils in massage, this study was per-
formed with the aim to “compare the effect of foot massage
with grape seed oil and sweet almond oil on physiological leg
edema during pregnancy.”
2. Materials and Methods
is randomized clinical trial study was conducted on a
number of primigravidae referred to health centres in
Zahedan, Iran, from August 2016 to November 2017. e
sample size was calculated using the following formula
(equation (1)) based on a previous study [22]:
sample size �z1− (α/2) + z1−β
2s2
1+s2
2
x1−x2
2.(1)
Using a power of 90% and taking into account the 95%
confidence interval, the required sample size was calculated
to be 24 for each group (x1�4/7, x2�3/3, s1�1/7, and
s2�1/2). Assuming 10% for attrition, 30 primigravidae were
needed for each group.
In this study, a multistage sampling technique was used.
First, the city was divided into five geographical regions
including the north, south, east, west, and central. Five
health centres were chosen randomly from each region.
Initial screening was done on 207 women with a gestational
age of 30 to 40 weeks, of whom 96 met the trial criteria and
agreed to participate in this study. e inclusion criteria
were 18–35 years of age, primigravid, normal singleton
pregnancy, and 1+ or 2+ pitting edema in feet. e exclusion
criteria were any underlying diseases or history of them (e.g.,
diabetes, hypertension, preeclampsia, and thrombophlebi-
tis), history of infertility, drug abuse, existence of wound and
skin lesions at the massage site, consumption of a specific
drug or diet to relieve edema during the study, emergency
termination of pregnancy or preterm labor, injury or serious
damage in the lower legs, development of preeclampsia
during the study, and lack of participation in any massage
session and foot circumference assessments. e researcher
(MN) explained the aim of the study to the participants.
ose who gave written consent were matched and then
randomly allocated to one of the three groups (massage with
grape seed oil, massage with sweet almond oil, and without
intervention). Randomization was done using a random
number table generated by a spreadsheet (Excel). e in-
tervention and control groups were matched statistically for
age and gestational age, and thus, groups were formed with
homogeneous distribution (P�0.47 and P�0.39,
respectively).
e intervention groups received usual health care and a
daily 20-minute foot massage with grape seed oil or
sweet almond oil. e control group received usual health
care. Usual health care included some advices about leg
edema such as “avoid hanging your legs during the day” and
“when resting, hold your feet above the ground.”
Participants were interviewed, observed, and examined
to take sociodemographic information, medical history,
blood pressure, and obstetric characteristics. ey were
checked for kidney disease with a urine dipstick test. en,
the extent of leg edema was determined by pressing index
and middle fingers on the tibia bone for 30 seconds and
estimating the depth of the created troughs. After that,
circumferences of 3 parts of each leg including the ankle,
instep, and foot/toe junction (as shown in Figure 1) were
measured by a nonelastic tape measure for each group while
the subjects were sitting in an upright position. e ankle
circumference was measured medially and laterally above
the malleoli, where the diameter was the smallest. e instep
circumference was measured over the cuneiform and cuboid
bones distal to the heel, and the foot/toe junction circum-
ference was measured at the distal end of the foot, at the
metatarsal-phalanges (MP) joint (where the toe joins the
foot). e second measurement of the circumferences was
done on the fifth day of intervention for the three groups.
ese measurements were took on an average of 15 minutes.
e measurements were done by MR in a private room in the
health centres while she was blind about the assignment of
people to groups.
e intervention groups were given a 10-minute massage
on each foot (a total of 20 minutes of massage for each
person) by MN. Before each massage, the researcher washed
her hands and made them warm by rubbing them together.
Five different movements of massage taken from the Çoban
and S
¸irin study were used in this study [20]. e participants
were asked to hold their foot firmly, and then the masseur
started massaging following five movements: (1) striking in
the entire foot from the toes to the ankle along the top of the
foot using the whole hand and returning under the foot to
the toes using less pressure, (2) kneading the foot from the
toes to the ankle using thumbs while supporting the foot
with the fingers underneath, (3) striking the skin surface
between each tendon on the top of the foot one after another
using thumbs, (4) grasping the foot with both hands and
gently manipulating from side to side, and (5) holding the
2Evidence-Based Complementary and Alternative Medicine
toes with one hand while the other hand supported the foot
and the toes were gently bent backward and forward. Each of
these movements was performed 10 times in the same order
for each foot in turn in each session. e researcher reduced
the effects of the masseur’s hand fatigue on massaging and
pressure on each leg by changing massage sequences in each
session. e massage began from the right foot on the first
day and from the left foot on the second day and continued
in the same way until the fifth day. e massage sessions
were held every day at 11 o’clock for 5 days. For convenience
of pregnant women, the intervention sessions were held at
the participants’ houses except the first and the fifth sessions
which were held at the health centres. Grape seed oil for one
intervention group and sweet almond oil for the other in-
tervention group were used. Each bottle contained 60 cc of
sweet almond oil or grape seed oil with a purity of 95%
approved by a laboratory. Sweet almond oil and grape seed
oil were purchased directly from Barij Essence Pharma-
ceutical Company and Mahdarou Pharmaceutical Com-
pany, respectively.
It should be noted that, before the intervention, massage
therapy was taught to the researcher (MN) by a reflexologist,
and after the specialist confirmation, the intervention began.
SPSS version 21 was used for statistical analysis. Dis-
tribution of the data was tested using the Shapiro–Wilk test.
Data are presented as mean ±SD and frequency (per-
centage). e chi-square, Fisher’s exact test, and one-way
ANOVA were used to compare proportions between the
three groups. Within-group changes were assessed using a
paired t-test. Between-group differences were assessed using
one-way ANOVA and Tukey’s test. A Pvalue less than 0.05
was considered to be statistically significant.
3. Results
ere were 30 participants in each group. Four participants
from the intervention groups and two from the control
group withdrew from the study before completing it. e
reasons for withdrawal are listed in Figure 2. Descriptive
statistics for the three groups’ means, standard deviations,
and ranges are expressed in Table 1.
e three groups were not significantly different in terms
of demographic characteristics, obstetric characteristics,
eating habits, activity and rest levels, and amount of fluid
and salt intake before the intervention. e results of the
average measurements of the participants’ left and right
ankles, insteps, and MP joints in the intervention and
control groups before and after the intervention are shown
separately in Table 2. e paired t-test showed a significant
difference in the intervention and control groups before and
after the intervention in terms of the average circumferences
of ankles, insteps, and MP joints for both legs. Results of
evaluating the measured circumferences of both legs of each
participant during two consecutive measurements indicated
reduction of the sizes in the two intervention groups and
their increase in the control group.
Results of the one-way ANOVA test showed a significant
difference between the three groups in terms of the average
changes in the measured circumferences (Table 3). Tukey’s
test that ran to test pairwise comparisons among means
indicated significant differences between both intervention
groups with the control group. However, the difference was
not significant between the two intervention groups.
4. Discussion
e results of this study showed a significant difference
between the average changes in the measured circumfer-
ences of feet in the three groups: the grape seed oil group, the
sweet almond oil group, and the control group. Tukey’s test
that ran to compare the groups two by two indicated sig-
nificant differences between the grape seed oil group and the
control group and also between the sweet almond oil group
and the control group. However, the difference was not
significant between the two intervention groups. is means
that massage with both oils led to reduction in the measured
circumferences of feet after five days of intervention com-
pared to that before the intervention. As it is shown in
Table 3, despite the fact that the difference in the two in-
tervention groups was not statistically significant, the mean
reduction of edema in the sweet almond oil group (except
right and left ankles) was slightly greater than that in the
grape seed oil group. erefore, the research hypothesis
regarding the greater effect of grape seed oil on reducing the
amount of edema in comparison with sweet almond oil was
rejected.
Rahimikian et al. in a study on the effects of foot massage
on physiological edema of pregnancy confirmed the effec-
tiveness of massage in reducing feet edema. e differences
in mean changes in the massage group in the right ankle, left
ankle, right instep, left instep, right MPJ, and left MPJ were
reported as −0.036, −0.025, −0.020, −0.025, 0.032, and
−0.037, respectively [21]. e current study and Rahimikian
et al.’s study were similar in terms of the number of days of
massage and the method of massage. However, there were
some differences between these two studies in the case that
Rahimikian et al.’s study compared two groups: massage and
control. Plus, they used baby oil for massage. Grape seed oil
and sweet almond oil containing antioxidants, vitamins E
and B, amino acids, and flavonoids when compared with
baby oil, a neutral oil, can be more effective in improving
blood flow and consequently reducing edema [23]. us, it
Ankle
Instep
MP joint
Figure 1: Lower leg circumference measurement (retrieved from
the Çoban and S¸irin study in 2010). MP joint: metatarsal-phalanges
joint.
Evidence-Based Complementary and Alternative Medicine 3
can be concluded that the more effective the oils used in a
massage, the greater the reduction in edema and its resultant
discomforts will be.
In another study conducted by Rahimikian et al., re-
garding the effectiveness of massage and foot elevation in
physiological edema, similar results to those of the previous
study were obtained [24]. e differences in mean changes in
the massage group in the right ankle, left ankle, right instep,
left instep, right MPJ, and left MPJ were reported as −0.042,
−0.045, −0.042, −0.046, 0.042, and −0.046, respectively. e
difference between Rahimikian et al.’s study and the current
study was that they had two types of interventions: massage
and foot elevation. Also, Rahimikian et al. used baby oil for
massaging. e results of this study indicated much more
impact of massage on reducing edema, compared to
Rahimikian et al.’s study. Massage in the present study was
more effective than that in Rahimikian et al.’s study which
may be due to differences in geographical location and
climatic conditions in the two studies. Rahimikian et al.’s
study was conducted in the north of Iran with a warm and
humid climate, while the present study was conducted in the
southeast of Iran with a warm and dry climate. Humidity
Table 1: Demographic characteristics by groups.
Characteristics
Grape seed oil group
(n�30)
Sweet almond oil group
(n�30) Control group (n�30)
Mean SD Mean SD Mean SD
Age (years) 25.3 4.06 26.7 5.01 25.63 4.77
Gestational age (weeks) 34.17 2.36 34.01 2.57 33.42 1.59
207 women assessed according to
inclusion and exclusion criteria
96 women were eligible and
randomized
2 withdrew: one
for leg fracture
and another
for travelling
Grape seed
oil group
n=32
Completed study
n=30
Completed study
n=30
Completed study
n=30
Sweet almond
oil group
n=32
2 withdrew: one did not
attend to the centre for
measurement and
another did not present
at home for taking
massage
2 withdrew: they
did not attend to
the centre for
measurement
Control group
n=32
111 were not eligible
for participation
Figure 2: Recruitment and retention of participants in the study.
Table 2: Average scores of lower leg circumferences by groups.
Variable
Group
Sweet almond Grape seed Control
Mean ±SD nMean ±SD nMean ±SD n
e amount of edema before intervention
Right foot
Ankle 23.1 ±2.5 30 23.1 ±1.9 30 23 ±1.6 30
Instep 23.6 ±1.7 30 23.6 ±1.3 30 23.4 ±1.1 30
MPJ 23.0 ±1.3 30 23.0 ±1.3 30 22.7 ±1.2 30
Left foot
Ankle 23.2 ±2.5 30 23.1 ±2.0 30 22.9 ±1.6 30
Instep 23.6 ±1.7 30 23.4 ±1.4 30 23.2 ±1.2 30
MPJ 23.0 ±1.3 30 22.8 ±1.2 30 22.5 ±1.0 30
e amount of edema on day 5 after intervention
Right foot
Ankle 22.5 ±2.4 30 23.5 ±2.0 30 22.1 ±1.5 30
Instep 23.1 ±1.7 30 23.9 ±1.5 30 23.0 ±1.1 30
MPJ 22.5 ±1.3 30 23.2 ±1.4 30 22.2 ±1.1 30
Left foot
Ankle 22.5 ±2.5 30 23.5 ±2.0 30 22.1 ±1.6 30
Instep 23.0 ±1.6 30 23.7 ±1.5 30 22.9 ±1.1 30
MPJ 22.5 ±1.3 30 23.1 ±1.2 30 22.1 ±1.0 30
MPJ: metatarsal-phalanges joint.
4Evidence-Based Complementary and Alternative Medicine
causes the fluctuation of body fluids and swelling of tissues
[25].
Mollart in a comparative study on the effect of re-
flexology techniques (lymphatic reflexology and relaxing
reflexology) versus rest on the amount of edema showed that
rest is more effective than reflexology techniques, focusing
on a specific pressure point, in reducing feet edema [22]. e
duration of the intervention was 15 minutes per session. e
participants’ legs were massaged for a few minutes to make
them warm before the intervention. Also, grape seed oil was
used for massage in the lymphatic reflexology group which
was more effective in reducing edema compared to the
relaxing reflexology group for whom no oil was used.
However, the difference was not significant. e differences
in mean changes in the reflexology with grape seed oil group
in the right ankle, left ankle, right instep, left instep, right
MPJ, and left MPJ were −0.06, −0.10, −0.03, −0.04, 0.03, and
−0.29, respectively. ese differences were much less
compared to the differences in mean changes in the current
study. e reasons behind this could be the difference in
methods, frequency, and duration of the massage.
Çoban and S
¸irin in a study on the effect of foot massage
on physiological edema showed a 20-minute foot massage
with body oil is effective in reducing feet edema [20]. e
Çoban and S
¸irin study was conducted on 80 pregnant
women in five 15-minute sessions and significantly reduced
naverage of every measured area in feet except left leg
circumference in the massage group compared to the
control group. In the Coban and S
¸irin study, baby oil was
used. Differences in mean changes in the Coban and S
¸irin
study were lower than those in the current study. ese
differences may be because of applying different types of
oils and different massage sequences in the two studies. In
the current study, massage began from the right foot on the
first day and from the left foot on the second day and
continued in the same way until the fifth day. Further
reasons for the differences in the amount of edema re-
duction between the current study (Table 3) and other
studies may be more amount of foot edema in women in
Zahedan. is may be due to ethnicity [26], prolonged
standing and lack of adequate rest, lack of proper diet
(excess salt consumption and inadequate intake of fruits
and vegetables), lack of exercise, and lower economic levels
[27]. Another possible reason for more amount of foot
edema in women in Zahedan is the high prevalence of the
iron deficiency anemia [28]. Leg edema is one of the clinical
signs of anemia [29].
On reviewing the literature, no articles examining the
effect of sweet almond oil or other effective oils on edema
were found, and most studies dealt with lubricant gel or baby
body oil. However, the impressive issue in this study was a
very good effect of both grape seed and sweet almond oils on
reducing edema. Sweet almond oil and grape seed oil are rich
in vitamin E, vitamin B, amino acids, and flavonoids which
with their strong antioxidant properties result in repairing
damaged vessels and improving environmental blood flow
[18]. e study of historical documents shows that massage
is the oldest form of physical therapy that has been used by
humans. Massaging helps return venous blood flow through
the pumping action caused by muscle compression. is
may lead to edema reduction in lower extremities [21]. So, it
is better to use an effective oil to increase the impact of
massage on reducing much more amount of edema in a
shorter time.
4.1. Limitations of the Study. Lack of access to a number of
participants at the designated time in 5 consecutive days was
a limitation of this study. erefore, for these participants,
massages were done an hour earlier or later than the first
day.
5. Conclusion
e findings of this study confirmed the effectiveness of foot
massage using grape seed and sweet almond oils to reduce
pregnancy physiological edema. erefore, foot massage
with appropriate oils can be used as a useful technique by
trained midwives in prenatal care centres or at pregnant
women houses. As recommendations for future researches,
studying the durability of the massage effect after the
massage therapy sessions as well as training pregnant
women for doing the massages themselves can be
mentioned.
Table 3: Differences in mean foot measurements across the three groups (between day 1 and day 5).
Result of ANOVA test Variable Group
Control Sweet almond Grape seed
Mean measurement changes
Right foot
Ankle 0.396 −0.713 −0.776 F�61.57
P�0.001
Instep 0.240 −0.460 −0.440 F�28.24
P�0.001
MPJ 0.266 −0.496 −0.476 F�21.35
P�0.001
Left foot
Ankle 0.403 −0.770 −0.770 F�50.67
P�0.001
Instep 0.306 −0.523 −0.366 F�39.59
P�0.001
MPJ 0.280 −0.440 −0.363 F�17.11
P�0.001
MPJ: metatarsal-phalanges joint.
Evidence-Based Complementary and Alternative Medicine 5
Data Availability
No data were used to support this study.
Ethical Approval
is study was approved by the Ethics Committee of Zahedan
University of Medical Sciences (IR.ZAUMS.REC.1394.149).
Consent
Informed consent form was obtained from the participants
after explaining the study objectives and after confidentiality
of data was guaranteed by the researchers.
Conflicts of Interest
e authors declare that there are no conflicts of interest
regarding the publication of this paper.
Acknowledgments
Special thanks are due to participants and respected staff of
health centres in Zahedan. Financial support for this study
was provided by the Zahedan University of Medical Sciences.
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6Evidence-Based Complementary and Alternative Medicine
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