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Archives of Orthopedics and Rheumatology V2 . I2 . 2019
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acid.
Archives of Orthopedics and Rheumatology
ISSN: 2639-3654
Volume 2, Issue 2, 2019, PP: 04-11
Understanding Collagen Supplements in Arthritis –
Immunomodulation with Undenatured Collagen II
Versus Cartilage Building with Hydrolysed Collagen II
Varsha Narayanan1*, Rajesh Gandhi2
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drvarsha@rediffmail.com
*Corresponding Author: Varsha Narayanan, Health and Pharmaceutical Consultant, Dr Varsha’s Health Solutions,
Andheri west, Mumbai, India.
Abstract
Rheumatoid Arthritis is known to have a T cell mediated autoimmune aetiology causing joint cartilage
destruction. Osteoarthritis, though regarded as a degenerative disease, also shows a T cell immune response
which can perpetuate the cartilage loss. Supplementing hydrolysed Collagen type II to aid the body rebuild
joint cartilage in the scenario of continuous cartilage destruction may not give the desired results. Therefore,
option in both Rheumatoid Arthritis and Osteoarthritis.
Keywords: Rheumatoid Arthritis, Osteoarthritis, Cartilage, Undenatured Collagen Type II, T cell, autoimmune,
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found in RA patients.9
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Understanding Collagen Supplements in Arthritis – Immunomodulation with Undenatured Collagen II
Versus Cartilage Building with Hydrolysed Collagen II
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Archives of Orthopedics and Rheumatology V2 . I2 . 2019
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destruction issuppressed.
Understanding Collagen Supplements in Arthritis – Immunomodulation with Undenatured Collagen II
Versus Cartilage Building with Hydrolysed Collagen II
Fig 1. Mechanism of Action of Undenatured (Native) Collagen Type II.
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Arthritis.
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Later two separate studies
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P
studies.
Understanding Collagen Supplements in Arthritis – Immunomodulation with Undenatured Collagen II
Versus Cartilage Building with Hydrolysed Collagen II
Difference between Undenatured and Hydrolysed Collagen Type II
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peptides
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Archives of Orthopedics and Rheumatology V2 . I2 . 2019
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across 18 Orthopaedic doctors in India.28
headache) was seen.
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and function in OA and other arthritic conditions.
progression of osteoarthritis in patients diagnosed
Understanding Collagen Supplements in Arthritis – Immunomodulation with Undenatured Collagen II
Versus Cartilage Building with Hydrolysed Collagen II
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remained unchanged. (P < 0.01)
purchasing it on their own. It is important to therefore
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Understanding Collagen Supplements in Arthritis – Immunomodulation with Undenatured Collagen II
Versus Cartilage Building with Hydrolysed Collagen II
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Arthritis
Research & Therapy
International Journal
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the treatment of osteoarthritis and other joint
Res Opin.
Understanding Collagen Supplements in Arthritis – Immunomodulation with Undenatured Collagen II
Versus Cartilage Building with Hydrolysed Collagen II
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on osteoarthritis. .
Understanding Collagen Supplements in Arthritis – Immunomodulation with Undenatured Collagen II
Versus Cartilage Building with Hydrolysed Collagen II
Citation:
Varsha Narayanan, Rajesh Gandhi
.
Understanding Collagen Supplements in Arthritis –
.
Archives of Orthopedics and Rheumatology. 2019; 2(2): 04-11.
Copyright: © 2019
Varsha Narayanan, Rajesh Gandhi
.
This is an open access article distributed under the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any
medium, provided the original work is properly cited.