Abstract

Apple cider vinegar contains acetic acid, polyphenols, number of vitamins and minerals that make it a beneficial therapeutic food for diabetes and other diseases. Diabetes mellitus is one of the most prevalent diseases worldwide. Apple cider vinegar has anti-hyperglycemic properties. It lowers the blood sugar levels. It also controls weight loss, which makes it another reason to be useful for diabetic patients who are generally overweight. Apple cider vinegar also reportedly has anti-hyperlipidemic effects. Key words: Apple cider vinegar, Anti-hyperglycemic Properties, Diabetes Mellitus, Hyperlipidemia
... The present study observes a significant reduction in the weight of the patients after treatment with combination of metformin and apple cider vinegar with a subsequent decline in the BMI (Table 2), highlighting the role of this combination as a possibly successful therapy to augment weight loss in type 2 diabetics. There are multiple studies that support the claim of weight loss by metformin [18,19] and there is also emerging evidence of weight loss caused by apple cider vinegar [20], however there seems to be scarce information regarding the combination therapy of ACV with metformin. ...
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Aims: The aim of this study was to observe the effect of Apple Cider Vinegar (ACV) in combination with Metformin on the Body Mass Index (BMI) and glycemic control of newly diagnosed type 2 diabetic patients. Study Design: Single arm pre post quasi experimental clinical trial Place and Duration of Study: Department of Medicine of a tertiary care hospital and a Diabetes and Endocrinology clinic,based in Karachi,Pakistan from April to July 2019. Methodology: A total of 30 newly diagnosed type 2 diabetic patients were enrolled in the study (Males: 17; females: 13; age range: 27-55 years) after obtaining written informed consent. Body weight, BMI, Fasting Blood Sugar (FBS) and Hemoglobin A 1c (HbA 1c) of each patient were assessed before and after 12 weeks of treatment with Metformin 750 mg plus 2 tablespoons of Original Research Article Abid et al.; JPRI, X(X): xxx-xxx, 20YY; Article no.JPRI.53959 2 ACV per day. The baseline and post treatment values of the aforementioned were compared with each other. Results: In all the 30 patients, assessed after 12 weeks of treatment the weight was significantly reduced from 85.66±18.30 kg. to 82.96±18.43 kg with a consequently significant change in the BMI from 29.38±5.08 kg/m 2 to 28.43±5.16 kg/m 2. Moreover, the glycemic control, assessed as FBS and HbA 1c also showed significant reduction in FBS (127.76±9.17 to 121.23±9.54) and HbA 1c (7.14±0.29 to 6.92±0.29) after 12 weeks of treatment in all 30 patients (p<0.01) Conclusion: Apple Cider Vinegar seems to be effective therapy in combination with metformin for newly diagnosed type 2 diabetic patients in improving glycemic control as well as augmenting weight reduction.
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