Article

Possible traces of resonance signaling in the genome

Authors:
  • DNA Resonance Research Foundation
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Abstract

Although theories regarding the role of sequence-specific DNA resonance in biology have abounded for over 40 years, the published evidence for it is lacking. Here, the authors reasoned that for sustained resonance signaling, the number of oscillating DNA sequences per genome should be exceptionally high and that, therefore, genomic repeats of various sizes are good candidates for serving as resonators. Moreover, it was suggested that for the two DNA sequences to resonate, they do not necessarily have to be identical. Therefore, the existence of sequences differing in the primary sequence but having similar resonating sub-structures was proposed. It was hypothesized that such sequences, named HIDERs, would be enriched in the genomes of multicellular species. Specifically, it was hypothesized that delocalized electron clouds of purine-pyrimidine sequences could serve as the basis of HIDERs. The consequent computational genomic analysis confirmed the enrichment of purine-pyrimidine HIDERs in a few selected genomes of mammals, an insect, and a plant, compared to randomized sequence controls. Similarly, it was suggested that hypothetical delocalized proton clouds of the hydrogen bonds of multiple stacked bases could serve as sequence-dependent hydrogen-bond-based HIDERs. Similarly, the enrichment of such HIDERs was observed. It is suggested that these enrichments are the first evidence in support of sequence-specific resonance signaling in the genome.

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This paper continues the series of papers on DNA resonance signaling. The authors previously proposed that DNA is involved in the work of the mind directly and immediately via the network of optical fibers. The authors proposed the mechanism of signal transduction in DNA via a sequence-specific resonance between the clouds of delocalized charges in the base stack. It was computationally demonstrated that certain repetitive patterns of delocalized charge clouds were evolutionarily enriched in various genomes. Here, the authors propose that natural quantum computation in DNA in living cells is based on the tautomerization of basepairs and involves coordinated oscillations of hydrogen-bond protons and aromatic electrons. The authors expand the ORCH-OR theory to include the collapse of the wave function of aromatic electrons in purines and propose that such collapses and expansions produce the experience of consciousness and the perception of time. The above mechanisms are supported by an observation that the majority of the psychoactive drugs are aromatic and the suggestion that they modify the aromaticity of DNA by binding to it. Quantum mechanical considerations for the collapse of aromaticity by double proton transfer in basepairs are discussed in terms of the collapse of the wave function, loss of delocalization, and the dynamic balance between coherence and decoherence in DNA.
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Although there is plenty of evidence for the existence of the biofield, the evidence that DNA interacts with it is very limited. Therefore, the idea that the biofield is created by the mass of DNA in the organism remains a hypothesis. We will first briefly summarize the existing evidence and then briefly review our studies, in which we used computational genomics to reveal the traces of resonance signaling in the genome and provided statistical evidence for this resonance signaling.
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Preprint
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This paper continues the series of papers on DNA resonance signaling. Previously the authors proposed that DNA is involved in the work of mind directly and immediately via the network of optical fibers. The authors proposed the mechanism of signal transduction in DNA via a sequence-specific resonance between the clouds of delocalized charges in the base stack. It was computationally demonstrated that certain repetitive patterns of delocalized charge clouds were evolutionarily enriched in various genomes. Here, the authors propose that natural quantum computation in DNA in living cells is based on the tautomerization of basepairs and involves coordinated oscillations of hydrogen-bond protons and aromatic electrons. The authors expand the ORCH-OR theory to include the collapse of the wave function of aromatic electrons in purines and propose that such collapses and expansions produce the experience of consciousness and the perception of time. The above mechanisms are supported by an observation that the majority of the psychoactive drugs are aromatic and the suggestion that they modify the aromaticity of DNA by binding to it. Quantum mechanical considerations for the collapse of aromaticity by double proton transfer in basepairs are discussed in terms of the collapse of the wave function, loss of delocalization, and the dynamic balance between coherence and decoherence in DNA.
Chapter
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The theory of the morphogenic field suggests that chemical signaling is supplemented by electromagnetic signaling governing the structure and shape of tissues, organs and the body. The theory of DNA resonance suggests that the morphogenic field is created by the genomic DNA which sends and receives electromagnetic signals in a sequence-specific manner. Previously, the authors have proposed the existence of HIDERs, genomic elements that serve as antennas in resonance signaling and demonstrated that they occur nonrandomly and are conserved in evolution. Here, it is proposed that longitudinal hydrogen bonds exist in the double helix, that chains of these bonds form delocalized proton clouds, that the shapes of these clouds are sequence-specific and form the basis of sequence-specificity of resonance between HIDERs. Based on longitudinal hydrogen bonds, a proton DNA resonance code was devised and used to identify HIDERs which are enriched 20 fold in the genome and conserved in evolution. It was suggested that these HIDERs are the key elements responsible for DNA resonance signaling and the formation of the morphogenic field.
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The aim of the study was to evaluate the efficacy and safety of electromagnetic millimeter waves (MW) applied to acupuncture points in patients with rheumatoid arthritis (RA). Twelve patients with RA were exposed to MW with power 2.5 mW and band frequency 54-64 GHz. MW were applied to the acupuncture points of the affected joints in a double blind manner. At least 2 and maximum 4 points were consecutively exposed to MW during one session. Total exposure time consisted of 40 minutes. According to the study design, group I received only real millimeter wave therapy (MWT) sessions, group II only sham sessions. Group III was exposed to MW in a random cross-over manner. Pain intensity, joint stiffness and laboratory parameters were recorded before, during and immediately after the treatment. The study was discontinued because of beneficial therapeutic effects of MWT. Patients from group I (n=4) reported significant pain relief and reduced joint stiffness during and after the course of therapy. Patients from group II (n=4) revealed no improvement during the study. Patients from group III reported the changes of pain and joint stiffness only after real MW sessions. After further large-scale clinical investigations MWT may become a non-invasive adjunct in therapy of patients with RA.
Radio Electron. 8e9, 41e48
  • Biomed
Biomed. Radio Electron. 8e9, 41e48.
Embryonic holography: an application of the holographic concept of reality. DNA Decipher
  • Richard A Miller
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[Correction of long range interaction between biological objects using corner-cube reflectors]
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Acitretin plus UVB therapy for psoriasis. Comparisons with placebo plus UVB and acitretin alone
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[About possible influence on biological object electromagnetic fields]
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Embryonic holography: an application of the holographic concept of reality
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