Article

Comparison of Marginal Bone Loss Around Axial and Tilted Implants: A Retrospective CBCT Analysis of Up to 24 Months

Authors:
  • Fondazione Policlinico Universitario A. Gemelli IRCCS—Università Cattolica del Sacro Cuore
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Abstract

This clinical study retrospectively analyzed cone beam computed tomography (CBCT) images to determine the potential influence of implant inclination on peri-implant marginal bone loss after 18 to 24 months of functional loading. Twenty-five consecutive patients presenting with an edentulous or partially edentulous maxilla or mandible and an adequate bone volume for receiving oral implants were selected for analysis of the marginal bone loss around tilted and/or axial implants. The study population included patients rehabilitated with Toronto bridges (TBs), fixed partial dentures (FPDs), or single crowns (SCs) on axial and/or tilted implants. The primary outcome was the CBCT analysis of peri-implant marginal bone level change, depending on inclination of implants and type of prostheses. The secondary outcome was analysis of survival and success rates of tilted and axial implants. A significant difference was observed for peri-implant buccal bone loss (mean of axials 0.42 ± 0.06; mean of tilted 0.70 ± 0.09) (P = .009). The difference in peri-implant lingual/palatal/mesial/distal bone loss was not significant between axial and tilted implants (P > .05). No significant difference was observed between the marginal bone level and the type of prostheses for both tilted and axial implants in all the assessed sites (P > .05). The success rate for both tilted and axial implants was 100%, and no complications were observed for all the prosthetic rehabilitations, with a 100% survival rate. Compared to axial implants, tilted implants showed a significant statistical difference for peri-implant buccal bone loss, but no other differences were observed for peri-implant bone loss or for implant survival and success rate. Fixed partial or total rehabilitation using tilted or axial implants, or with tilted and axial implants, could be a reliable technique with advantages to patients and operators.

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... A total of 274 implants (137 axial and 137 tilted) were lost (2.45%). 22 Follow-up < 36 months (18 to 24 mo) Cucchi et al (2019) 23 Follow-up < 36 months (12-36 mo) Grandi et al (2019) 24 Follow-up < 36 months (12 mo) Francetti et al (2019) 25 > 10% patients with follow-up < 36 mo Pera et al (2019) 26 Not always a combination of axial and tilted implants Ferrini et al (2018) 27 Partial prostheses supported by 1 axial + 1 tilted implant Maló et al (2018) 28 Follow-up < 36 mo (6-48 mo) Maló et al (2018) 29 Follow-up < 36 mo ( 37 Not always a combination of axial and tilted implants Gherlone et al (2016) 38 Follow-up < 36 months (12 mo) Krennmair 40 Patients also reported in a subsequent publication Queridinha et al (2016) 41 Partial prostheses supported by axial and tilted implants Toljanic et al (2016) 42 Inadequate/incomplete report of implants Francetti et al (2015) 43 Patients also reported in a subsequent publication Francetti et al (2015) 44 Patients also reported in a subsequent publication Maló et al (2015) 45 Follow-up < 36 months (avg 36 mo (4 to 72 mo]) Maló et al (2015) 46 Follow-up < 36 months (average 14 mo (6 to 26 mo]) Maló et al (2015) 47 Patients also reported in a subsequent publication Tallarico et al (2015) 48 > 10% patients with follow-up < 36 mo Agliardi et al (2014) 49 Partial prostheses supported by 1 axial +1 tilted implant Agnini et al (2014) 50 Not all patients received tilted implants Balshi et al (2014) 51 Follow-up < 36 months (avg 26 mo [0 to 84 mo]) Tealdo et al (2014) 52 Not always a combination of axial and tilted implants Di et al (2013) 53 Follow-up < 36 months (avg 33. 57 Patients also reported in a subsequent publication Francetti et al (2012) 58 Patients also reported in a subsequent publication Galindo and Butura (2012) 59 Results at 12 mo (up to 84 mo of followup) Grandi et al (2012) 60 Follow-up < 36 mo (18 mo) Maló et al (2012) 18 Patients also reported in a subsequent publication Maló et al (2012) 61 Follow-up < 36 mo (avg 24 mo) Peñarrocha et al (2012) 62 65 Patients also reported in a subsequent publication Maló et al (2011) 16 Patients also reported in a subsequent publication Maló and Nobre (2011) 66 Partial prostheses supported by axial and tilted implants Parel and Phillips (2011) 67 Follow-up < 36 months (4 to 33 mo) Tealdo et al (2011) 68 Not always a combination of axial and tilted implants Agliardi et al (2010) 69 Follow 77 Patients also reported in a subsequent publication Tealdo et al (2008) 78 Not always tilted + axial implants; followup < 36 mo (average 20 mo (13-2 8mo]) Testori et al (2008) 79 Patients reported in another subsequent publication Capelli et al (2007) 86 Removable prosthesis Aparicio et al (2001) 87 Fixed partial prosthesis Krekmanov et al (2000) 13 Mainly fixed partial prosthesis ...
... No significant heterogeneity among studies was detected either in the prospective (P = . 22) or in the retrospective subgroup (P = .43). ...
Article
Purpose: To evaluate the performance of fixed complete dental prostheses supported by axial and tilted implants after at least 3 years of follow-up. Materials and methods: An electronic search plus a hand search up to April 2021 was undertaken. Clinical studies were selected using specific inclusion criteria, independent of the study design. The main outcomes were cumulative implant survival rate, marginal bone level changes, and complications, after ≥ 3 years of follow-up. The difference in outcomes between axial and tilted implants and between the maxilla and mandible was evaluated using meta-analysis and the Mantel-Cox test. Results: Out of 824 articles retrieved, 24 were included. In total, 2,637 patients were rehabilitated with 2,735 full prostheses (1,464 maxillary, 1,271 mandibular), supported by 5,594 and 5,611 tilted and axial implants, respectively. In a range between 3 and 18 years of follow-up, 274 implants failed. The cumulative implant survival rate was 93.91% and 99.31% for implants and prostheses, respectively. The mean marginal bone level change was moderate, exceeding 2 mm in only two studies. Marginal bone loss was significantly lower around axial compared with tilted implants (P < .0001), whereas it was not affected by arch (maxilla vs mandible; P = .17). Conclusion: Fixed complete dental prostheses supported by tilted and axially placed implants represent a predictable option for the rehabilitation of edentulous arches. Further randomized trials are needed to determine the efficacy of this surgical approach and the remodeling pattern of marginal bone in the long term.
... Many authors have compared clinical and radiographic outcomes of axial versus tilted implants without finding significant differences [33][34][35]. With regard to short and ultrashort implants, only finite element analysis (FEA) studies had compared outcomes related to different angulation. ...
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Does the angulation of ultrashort implants influence the stability of the peri-implant bone? The present study aimed to evaluate the effectiveness of non-axial ultrashort implants after 2 to 9 years of follow-up in resorbed alveolar ridges. All partially edentulous patients with ultrashort implants (< 6 mm) used in the posterior region of an atrophic mandible or maxilla, to support partial dentures in conjunction with standard implants, were included in this study. Peri-implant bone loss, success and survival rates, crestal bone levels, crown-to-implant ratio and implant angulation were measured for each implant. Implants were divided into two groups: straight implants with angulation < 17° (control group) and tilted implants with angulation > 17° (test group). Statistical analysis was used to find any significant differences between the two study groups and to investigate significant linear correlations among all the variables (p = 0.05). A total of 42 ultrashort implants with a mean of 4 years of follow-up were included: 20 ultrashort axially loaded implants and 22 tilted implants. Mean crestal bone levels from baseline loading to maximum follow-up did not reveal statistical differences in regard to PBL; mean success and survival rates were 100% in all groups. PBL, success and survival rates of axial ultrashort implants and tilted ultrashort implants are comparable to those of conventional implants. This retrospective study revealed that ultrashort implants, even when placed with an angulation > 17°, can safely be used to support partial fixed prostheses. Further prospective clinical studies with larger samples and prospective design are needed to confirm these findings.
... In the present study, the angled implant showed a higher significant marginal bone loss than the straight implant on the prosthesis and 6 months after loading. In agreement with our results, Bruschi et al. (25) determined the possible influence of the implant inclination on the periimplant marginal bone loss after 18 to 24 months of functional loading. Compared to axial implants, tilted implants showed a significant statistical difference for peri-implant buccal bone loss, but no further differences were observed for peri-implant bone loss or for implant survival and success rate. ...
... It must be pointed out although that we found a particularly small difference (0.38 mm) which might not be significant from a clinical viewpoint. Many articles available in the literature have stated the opposite [30,31], but, to our knowledge, this is the first paper, together with one previously published by our group [32], that has observed the MBL on a CBCT analysis which provides an higher accuracy, when compared to bidimensional exams. Moreover, bidimensional exams can only offer an evaluation of the mesial and distal bone levels but cannot analyze the More so, implants coming from the same patient had similar amount of bone loss, and this concordance was found to be much more relevant than the effects of all the other variables; this is key as it shows that implant-level variables (such as position and inclination) have a marginal effect regarding peri-implant health when compared to patient-level characteristics (i.e., hygiene levels and prosthetic design). ...
Article
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Introduction: Full-arch, implant-supported hybrid restorations, employing tilted implants, can offer an efficient way of treating edentulous patients. Several factors, such as the timing of implant placement and the inclination of the fixture, can have a detrimental effect on their stability. This retrospective study is aimed at discerning the role played by those factors. Materials and methods: Patients treated with full-arch, implant supported restorations were selected for this study; cone-beam computed tomography (CBCT) images, taken 3 months and 3 years after delivery of the final restoration, as well as peri-implant values, were obtained and compared; bone loss was measured on four sites for each implant and then averaged. These patients were recalled, and the OHIP-5 questionnaire was administered. Results: 21 patients, with a mean age of 53 years, were included in the present analysis. 108 implants were placed, and 25 Toronto prostheses were delivered. According to a mixed-model analysis, tilted implants (0.51, p < 0.001) had a higher rate of bone loss, while implants placed in a healed ridge suffered less bone loss than immediate implants (-0.21, p < 0.001). Patient-level variables have a significant effect on this variable, as implants coming from the same subject share a similar risk of bone loss. The mean response to the self-administered OHIP-5 questionnaire was 1.53 ± 0.29; other variables did not have a statistically significant effect on this outcome. Discussion/Conclusions. The results of the present study show that Toronto bridges prostheses are an efficient procedure for treating edentulous patients, as their oral-related quality of life is reported as satisfactory even 7 years after delivery of the restoration. Tilted and immediate implants are more at risk of bone loss. Implants coming from the same subject share a similar risk of bone loss.
... This method of tilted implant with immediate function is increasingly used in clinical dental treatment [4]. However, the latest consensus statement and research suggested that tilting the implant may affect peri-implant bone response [5,6]. Also, the peri-implant bone loss around the cervical region could be caused by stress shielding effect [7,8]. ...
Article
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The tilted implant with immediate function is increasingly used in clinical dental therapy for edentulous and partially edentulous patients with excessive bone resorption and the anatomic limitations in the alveolar ridge. However, peri-implant cervical bone loss can be caused by the stress shielding effect. Herein, inspired by the concept of “materiobiology”, the mechanical characteristics of materials were considered along with bone biology for tilted implant design. In this study, a novel Ti–35Nb–2Ta–3Zr alloy (TNTZ) implant with low elastic modulus, high strength and favorable biocompatibility was developed. Then the human alveolar bone environment was mimicked in goat and finite element (FE) models to investigate the mechanical property and the related peri-implant bone remodeling of TNTZ compared to commonly used Ti–6Al–4V (TC4) in tilted implantation under loading condition. Next, a layer-by-layer quantitative correlation of the FE and X-ray Microscopy (XRM) analysis suggested that the TNTZ implant present better mechanobiological characteristics including improved load transduction and increased bone area in the tilted implantation model compared to TC4 implant, especially in the upper 1/3 region of peri-implant bone that is “lower stress”. Finally, combining the static and dynamic parameters of bone, it was further verified that TNTZ enhanced bone remodeling in “lower stress” upper 1/3 region. This study demonstrates that TNTZ is a mechanobiological optimized tilted implant material that enhances load transduction and bone remodeling.
... As said, in the study of Menchini-Fabris and co-workers, immediate implant placement showed lower MBL loss compared with delayed implant placement after 3-year s [11]. Moreover, other studies confirmed that immediate implant placement not only preserve the preexisting soft and hard tissues architecture, but also reduce the surgical procedures, decrease the overall treatment timing and increase the patient satisfaction [12][13][14]. ...
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Purpose: The present prospective randomized study aimed to assess and compare the influence of immediately placed, immediately restored, newly designed platform switched (PFS) Maxi-Z plus dental implant on marginal bone level (MBL) and the peri-implant soft tissues versus platform matched (PFM) Maxi-Z dental implant. Materials and methods: A total of 114 endosseous implants in 50 patients with different implant designs (PFS (n=25 patients, 58 implants), and PFM (n=25 patients, 56 implants)) were reviewed for implant mobility, MBL, and pink esthetic score (PES) for 1 year of the insertion. Results: Upon comparing changes of the clinical and radiographic parameters between the two groups, the changes of Periotest M values, MBL changes, and PES changes from baseline to 6 months were found to be significantly improved in the study group when compared to control group. Conclusion: Within the present study limitations, results concluded that PFS implants demonstrated better conditions regarding peri-implant soft tissue and cause minimal MBL loss.
... The percentage of bone loss in the delayed group (27.1%) showed two times the percentage of bone loss in the immediate group (14.6%). This clearly confirmed that immediate placement and restoration of a single implant was a successful option of treatment in the case of single compromised teeth, as attested by previous authors with good results in terms of short/long-term success (close to 100%) and marginal bone loss (from 0.42 to 2.69 mm) [34,35]. Moreover, immediate placement of dental implant protocol seems to maintain the preexisting architecture of soft and hard tissues in most cases, as reported in the literature [36]. ...
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Introduction. Although retrospective analysis has shown immediate placement of implants (IIP) in the maxillary esthetic zone showing promising outcomes compared to delayed placement of implants following socket preservation (DIP), a direct comparison in a prospective, well-designed randomized fashion with adequate power analysis between the two implant placement protocols is still lacking. This study is aimed at radiographically evaluating the effect of IIP after extraction as compared to implant placed in preserved sockets 4 months following extraction (DIP) in terms of changes in buccal plate thickness(CBT) after 6 months of healing and evaluation of pink esthetic score (PES) for assessment of soft tissue changes and patient-related outcome measures (PROMs) using visual analogue scale (VAS). Materials and Methods. 25 implants were placed immediately following extraction in the IIP group, and 25 implants were placed four months following socket preservation with demineralized bovine bone mineral (DBBM) and advanced platelet-rich fibrin (A-PRF) in the DIP group, control group, in the maxillary esthetic region. CBCT was taken preoperatively and 6 months postoperatively to assess the dimensional changes in the buccal bone plates(CBT). PES and PROMs for pain threshold and patient satisfaction using VAS were evaluated at the time of implant placement and 6 months postoperatively. Results. Significant differences in mean reduction in buccal plate thickness (CBT) were found in the test group (IIP) 0.2±0.02 compared to the control group (DIP) which showed a mean reduction in CBT of 0.4±0.1 (p
... In one meta-analysis, the authors found no difference between axial or tilted implants in their long-term success. [3] In a recent study by Bruschi et al., [4] the authors compared marginal bone loss around axial and tilted implants rehabilitated with Toronto bridges, fixed partial dentures, and even single crowns. The conclusion of the study was no significant difference between marginal bone levels with any type of prosthesis. ...
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Implant-supported fixed dental prosthesis is a well-accepted treatment option for edentulism. Loss of teeth due to extensive caries or severe periodontitis presents a challenge to the clinicians. Young age disability with either of these problems can further make full-mouth rehabilitation on implants a complex procedure. The outcome of implant surgery with periapical infections and periodontal inflammation is unpredictable and often delays the placement of dental implants. Here, we describe a case of full-mouth reconstruction with implant-supported prosthesis in a young individual who lost all her teeth due to extensive caries. The journey from terminal dentition to functional esthetic rehabilitation was uneventful.
... This confirmed that immediate placement and restoration of a single implant was a successful option of treatment in the case of single compromised teeth, as attested by previous authors with good results in terms of short/long term success (close to 100%) and marginal bone loss (from 0.42 to 2.69 mm) [18,19]. Moreover, immediate placement of dental implant protocol seems to maintain the preexisting architecture of soft and hard tissues in most cases, as reported in the literature [20]. ...
Article
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Background: To investigate the middle-term effect on bone remodeling of different timings for different implant placement (immediate versus delayed). Methods: Patients with an anterior maxillary failing tooth were treated by single-crown supported by dental implant. Subjects were retrospectively analyzed for 3 years and assigned to one of two predictor groups: nine immediate versus 10 delayed implant placement (1-2 months after tooth extraction). The crestal bone loss around dental implants was measured with the cone beam computerized tomography by fusing pre-operative and post-operative data. Results: The percentage of volume loss registered at 1-year follow-up (%ΔV) was of 7.5% for the immediate group, which was significantly lower (p-values ≤ 0.0002) than the loss of 24.2% for the delayed group. At 3 years, there was a significant difference (p-values = 0.0291) between the two groups, respectively, with a volume loss of 14.6% and 27.1%. When different times were compared, the percentage of the volume loss for the immediate group was different (p-value = 0.0366) between the first and third year (7.5% and 14.6%, respectively). For the delayed group, no significant difference was registered between the 1- and 3-year follow-up. Conclusions: The bone loss around dental implant-supported single-crown with different timing of insertion appeared higher for the delayed group than the immediate group.
... Longevity can be assessed through the survival rate while success rate, probing depth (PD), bleeding on probing (BOP) and other radiographical outcomes are focused on the evaluation of the technical and biological effects of the therapy [2][3][4][5]. Patient-and operator-centered outcomes concerning implant treatment protocols are rare and mostly focused on the patient's satisfaction with the functional results obtained at the end of the treatment [6]. Scientific information about the effects of an implant therapy following a precise workflow as well as patient and operators' preferences should be considered to choose adequately which protocol to use. ...
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Background: Scientific information about the effects of implant therapy following a precise workflow and patient and operators’ preferences should be considered to choose which implant treatment protocol to use, and to achieve patient’s satisfaction and functional results. The aim of this study was to analyze implant rehabilitations with a fully digital workflow and compare this approach with a conventional one. Methods: This study comprises 64 patients treated with a fully digital approach and 58 patients treated using a conventional protocol. Patient and operator centered outcomes were assessed through two visual analogue scale (VAS) questionnaires. Results: The VAS questionnaire demonstrated better results for the digital workflow concerning anxiety, convenience, taste, nausea sensation, pain and breathing difficulties (p < 0.0001). The VAS questionnaire administered to the operators showed better scores for the digital approach in relation to anxiety, convenience, difficulties of the impression procedure and the workflow (p < 0.0001). A significant reduced mean time for the digital workflow as well as a reduced number of required visits were recorded. Conclusion: The analysis of a fully digital and a conventional protocol showed better results according to patient and operators’ preferences when a fully digital approach was used.
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Rehabilitation of atrophied edentulous arches with endosseous implants in the posterior regions is often associated with anatomic problems such as jaw shape and location of the mental loop, mandibular canal, and maxillary sinuses. The purpose of this investigation was to modify the method for implant placement in the posterior part of the jaws to extend fixed implant-connected prostheses further distally, and to reduce the length of cantilevers in complete-arch prostheses without transpositioning the mandibular nerve or performing bone grafting in the maxilla. Forty-seven consecutive patients were treated with implants (25 patients/36 mandibular implants, 22 patients/30 maxillary implants) placed in tilted positions. They were followed a mean of 40 months (mandibles) and 53 months (maxillae). In the mandible, implants close to the mental foramina were tilted posteriorly approximately 25 to 35 degrees. In the maxilla, the posterior implants were placed close to and parallel with the sinus walls and were titled anteriorly/posteriorly approximately 30 to 35 degrees. Patients gained a mean distance of 6.5 mm of prosthesis support in the mandible and 9.3 mm in the maxilla, as a result of implant tilting. There were no implant failures in mandibles. The cumulative success rates in the maxilla at 5 years were 98% for tilted implants and 93% for non-tilted implants. Paresthesias of the mental nerve were observed on 4 sides during the first 2 to 3 weeks after implant placement. Analysis of the load distribution in one mandibular case showed no significant difference between tilted and the non-tilted implants, and the improved prosthesis support was confirmed. Satisfactory medium-term results concerning osseointegration and significant extension of prosthesis support show that the method can be recommended. This technique may allow for longer implants to be placed with improved bone anchorage.
Article
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To evaluate retrospectively the surgical outcome of tilted implants in severely resorbed edentulous maxillas as an alternative to bone grafting and the prosthodontic outcome of posterior extension bridges on tilted implants. A total of 33 consecutive patients with severely resorbed edentulous maxillas participated in the study. In these patients, the maxillary bone volumes were insufficient for conventional placement of implants to support a fixed prosthesis. As an alternative to bone transplantation, a surgical technique with fenestration of the maxillary sinus to visualize the total amount of maxillary bone was used, followed by implant placement in a tilted manner along the anterior maxillary sinus wall. Thus, 4 to 6 implants of optimal length could be installed in each patient. Nineteen patients were included in this long-term follow-up study and were eligible for clinical evaluation at 8 to 12 years (mean, 10 years) after second-stage surgery. Each patient was examined clinically and radiographically. The 19 patients had a total of 103 implants. In 2 of these patients, 3 fixtures were lost during the first year after second-stage surgery. All other patients had all implants intact with functionally fixed dental prostheses, corresponding to a success rate of 97%. Radiographic examination showed bone resorption in 10% of the implants (10 implants in 5 patients with a total number of 27 implants), with a mean bone loss of 1.2 mm. Mucositis was seen in 47% of the patients. This long-term follow-up study (mean time, 10 years) demonstrates that patients with a severely resorbed maxilla can be treated successfully with conventional implant treatment. This simplified surgical technique can be an alternative to the more resource-demanding technique with bone grafting.
Article
Full-text available
The aims of this study were to assess the treatment outcome of immediately loaded full-arch screw-retained prostheses with distal extensions supported by both upright and tilted implants for the rehabilitation of edentulous jaws and to compare the outcomes of upright versus tilted implants. At 4 study centers, 342 Osseotite NT implants were consecutively placed in 65 patients (96 implants were placed in 24 mandibles and 246 implants in 41 maxillae). The 2 distal implants were tilted by 25 to 35 degrees. Provisional full-arch restorations made of a titanium framework and acrylic resin teeth were delivered within 48 hours of surgery and immediately loaded. The final prosthesis was delivered after 3 months of healing. Three implants failed during the first year and another 2 within 18 months of loading in the maxilla. The cumulative implant survival rate for the maxilla was 97.59% for up to 40 months of follow-up. No implant failure was recorded for the mandible. The prosthetic success rate was 100%. Marginal bone loss around upright and tilted implants was similar. Patients were satisfied of their esthetics, phonetics, and function. The preliminary results of this study suggest that immediate rehabilitation of the edentulous maxilla and mandible by a hybrid prosthesis supported by 6 or 4 implants, respectively, may represent a viable treatment alternative with respect to more demanding surgical procedures. The clinical results indicate that immediately loaded tilted implants may achieve the same outcome as upright implants in both jaws.
Article
PURPOSE: To evaluate plaque accumulation, peri-implant soft tissue inflammation, and bone resorption in patients with immediately loaded implants supporting fixed full-arch prostheses. MATERIALS AND METHODS: A convenience sample of 72 patients treated with fixed full-arch prostheses supported by four to six immediately loaded implants was selected. Bleeding on probing (BOP), Plaque Index (PI), and peri-implant bone loss were measured. The Sixth European Workshop on Periodontology definitions of mucositis and peri-implantitis were used, and collected data were analyzed using a nonparametric test (Spearman's rank correlation). Correlation coefficients (ρ) were defined as follows: < 0.2 = very weak; 0.2 to 0.39 = weak; 0.4 to 0.59 = moderate; 0.6 to 0.79 = strong; 0.8 to 1.0 = very strong. RESULTS: A total of 331 implants were analyzed. The mean follow-up observation time was 5.8 years (range: 1 to 14 years); mean PI and BOP were 61.7% and 21.1%, respectively; and mean bone loss was 0.89 mm (standard deviation [SD] 1.09). The mean probing depth was 1.8 mm (range: 0.5 to 5 mm). Five patients presented with one implant each affected by peri-implantitis (6.9%), and 15 patients presented with at least one implant affected by mucositis (20.8%). No correlation was found between PI and bone resorption (P = .08). Very weak correlations were found between BOP and bone resorption (ρ = 0.18; P = .001) and between PI and BOP (ρ = 0.13, P = .019). CONCLUSION: The results suggest that plaque accumulation is correlated with peri-implant mucositis; however, plaque accumulation alone does not appear to be associated with bone resorption.
Article
Background: There is need for more scientific and clinical information on longer-term outcomes of tilted implants compared to implants inserted in an axial position. Purpose: Comparison of marginal bone loss and implant success after a 5-year follow-up between axial and tilted implants inserted for full-arch maxillary rehabilitation. Material and methods: The retrospective clinical study included 891 patients with 3564 maxillary implants rehabilitated according to the All-on-4 treatment concept. The follow-up time was 5 years. Linear mixed-effect models were performed to analyze the influence of implant orientation (axial/tilted) on marginal bone loss and binary logistic regression to assess the effect of patient characteristics on occurrence of marginal bone loss >2.8 mm. Only those patients with measurements of at least one axial and one tilted implant available were analyzed. This resulted in a data set of 2379 implants (1201 axial, 1178 tilted) in 626 patients (=reduced data set). Results: Axial and tilted implants showed comparable mean marginal bone losses of 1.14 ± 0.71 and 1.19 ± 0.82 mm, respectively. Mixed model analysis indicated that marginal bone loss levels at 5 years follow up was not significantly affected by the orientation (axial/tilted) of the implants in the maxillary bone. Smoking and female gender were associated with marginal bone loss >2.8 mm in a logistic regression analysis. Five-year implant success rates were 96%. The occurrence of implant failure showed to be statistically independent from orientation. Conclusions: Within the limitations of this study and considering a follow-up time of 5 years, it can be concluded that tilted implants behave similarly with regards to marginal bone loss and implant success in comparison to axial implants in full-arch rehabilitation of the maxilla. Longer-term outcomes (10 years +) are needed to verify this result.
Article
Aims: The use of tilted implants has recently gained popularity as a feasible option for the treatment of edentulous jaws by means of implant-supported rehabilitations without recurring to grafting procedures. The aim of this review was to compare the crestal bone level change around axially placed vs. tilted implants supporting fixed prosthetic reconstructions for the rehabilitation of partially and fully edentulous jaws, after at least 1 year of function. Materials and methods: An electronic search of databases plus a hand search on the most relevant journals up to January 2014 was performed. The articles were selected using specific inclusion criteria, independent of the study design. Data on marginal bone loss and implant survival were extracted from included articles and statistically analysed to investigate the effect of implant tilting, location, prosthesis type, loading mode and study design. The difference in crestal bone level change around axial vs. tilted implants was analysed using meta-analysis. Results: The literature search yielded 758 articles. A first screening based on titles and abstracts identified 62 eligible studies. After a full-text review, 19 articles (14 prospective and five retrospective studies) were selected for analysis. A total of 670 patients have been rehabilitated with 716 prostheses (415 in the maxilla, 301 in the mandible), supported by a total of 1494 axial and 1338 tilted implants. Periimplant crestal bone loss after 1 year of function ranged from 0.43 to 1.13 mm for axial implants and from 0.34 to 1.14 mm for tilted implants. In spite of a trend for a lower bone loss around axial implants with respect to tilted ones at 12 months, as well as after 3 or more years of function, no significant difference could be found (P = 0.09 and P = 0.30, respectively). The location (maxilla vs. mandible), the loading mode (immediate vs. delayed), the restoration type (full vs. partial prosthesis) and the study design (prospective vs. retrospective) had no significant effect on marginal bone loss. Forty-six implants (18 axial and 28 tilted) failed in 38 patients within the first year of function. All failures except five occurred in the maxilla. After 12 months of loading, the survival rate of implants placed in the maxilla (97.4%) was significantly lower as compared to the mandible (99.6%). No prosthesis failure was reported. Conclusions: Tilting of the implants does not induce significant alteration in crestal bone level change as compared to conventional axial placement after 1 year of function. The trend seems to be unchanged over time even though the amount of long-term data is still scarce. The use of tilted implants to support fixed partial and full-arch prostheses for the rehabilitation of edentulous jaws can be considered a predictable technique, with an excellent prognosis in the short and mid-term. Further long-term trials, possibly randomised, are needed to determine the efficacy of this surgical approach and the remodelling pattern of marginal bone in the long term.
Article
Background: Immediate implant placement (IIP) is a successful treatment and has the advantages of reducing time and increasing patient satisfaction. However, achieving predictable esthetic results with IIP presents a challenge because of naturally occurring bone loss postextraction. Therefore, the focused question of this systematic review is: What is the effect of IIP on crestal bone level (CBL) changes after at least 12 months of functional loading? Methods: Extensive literature review of the Cochrane and MEDLINE electronic databases and a manual search up to November 2012 identified eligible studies. Two reviewers independently assessed the study data and methodologic quality using data extraction and assessment forms. Results: Electronic and manual searches identified 648 relevant publications. A total of 57 articles satisfied the inclusion criteria. Sixteen studies had test and control groups; therefore, meta-analyses could be performed. The results demonstrated better CBL preservation around IIP compared with implant placement in healed/native bone at 12 months [CBL difference of -0.242 (95% confidence interval [CI], -0.403 to -0.080; P = 0.003)]. Similarly, platform switching around IIP showed better results compared with non-platform switching (CBL difference of -0.770 [95% CI, -1.153 to -0.387; P <0.001]). There was no difference in mean CBL changes with regard to one-stage or two-stage IIP protocol (-0.017 [95% CI, -0.249 to 0.216; P = 0.85]) or the use of immediate or delayed immediate implant loading (0.002 [95% CI, -0.269 to 0.272; P = 0.99]). Conclusions: Meta-analyses showed less CBL loss around IIP compared with implant placement in healed bone. Platform-switched implants showed greater crestal bone preservation than non-platform-switched implants. There was no significant difference in CBL with one- versus two-stage placement or use of immediate versus delayed IIP loading. Although there were statistically significant differences favoring IIP, the small differences may not be clinically relevant. Although IIP showed favorable outcomes for CBL changes, these results should be interpreted with caution because of high heterogeneity among studies.
Article
Objectives: The present study assesses the accuracy of three-dimensional (3D) cone beam CT (CBCT) and intra-oral radiography (CR) in visualizing peri-implant bone compared with histology. Methods: 26 titanium dental implants were placed in dog jaws with chronic type vestibular defects. After a healing period of 2 and 8 weeks (n = 12 dogs) the animals were sacrificed. CBCT scans and CR of the specimen were recorded. Dissected blocks were prepared, and histomorphometric analysis was performed. Both modalities were measured twice by two observers and compared with histomorphometry regarding bone levels and thickness around implants as well as length and diameter of implants. Results: Measurements of CBCT correlated well with histomorphometry of the vestibular bone level, oral bone thickness and implant length (all p-values <0.05). Compared with histomorphometry, the mean differences between CBCT and histomorphometry were between 0.06 and 2.61 mm. Mesial bone level (MBL) and distal bone level (DBL) were underestimated by both CR and CBCT. CR and histology measurements were only significantly correlated for implant length measurements. All intraclass correlations were highly significant. Conclusions: 3D CBCT provides usable information about bone in all dimensions around implants with varying accuracy. CR and CBCT perform similar in assessing MBL and DBL, but, within its limits, the CBCT can assess oral and buccal bone. Metallic artefacts limit the visualization quality of bone around implants and further research could elucidate the value of post-processing algorithms. When information about osseous perforation of implants is needed, CBCT may still provide clinically valuable information.
Article
Objective To compare the sequential healing at immediately loaded implants installed in a healed alveolar bony ridge or immediately after tooth extraction.Material and methodsIn the mandible of 12 dogs, the second premolars were extracted. After 3 months, the mesial roots of the third premolars were endodontically treated and the distal roots extracted. Implants were placed immediately into the extraction sockets (test) and in the second premolar region (control). Crowns were applied at the second and third maxillary premolars, and healing abutments of appropriate length were applied at both implants placed in the mandible and adapted to allow occlusal contacts with the crowns in the maxilla. The time of surgery and time of sacrifices were planned in such a way to obtain biopsies representing the healing after 1 and 2 weeks and 1 and 3 months. Ground sections were prepared for histological analyses.ResultsAt the control sites, a resorption of the buccal bone of 1 mm was found after 1 week and remained stable thereafter. At the test sites, the resorption was 0.4 mm at 1-week period and further loss was observed after 1 month. The height of the peri-implant soft tissue was 3.8 mm both at test and control sites. Higher values of mineralized bone-to-implant contact and bone density were seen at the controls compared with the test sites. The differences, however, were not statistically significant.Conclusions Different patterns of sequential early healing were found at implants installed in healed alveolar bone or in alveolar sockets immediately after tooth extractions. However, three months after implant installation, no statistically significant differences were found for the hard- and soft-tissue dimensions.
Article
Purpose: The purpose of this clinical investigation was to evaluate full-arch fixed-dental restorations supported by immediate loaded axial and tilted implants in a single-cohort study. Survival rate of axial and tilted implants was compared. Materials and methods: From 2006 to 2010, 30 patients were recruited and treated with dental implants. Provisional fixed-dental prostheses were screw-retained over axial or axial and tilted implants within 24 hours after surgery. Follow-ups at 6, 12, and 24 months and annually up to 5 years were scheduled, and radiographic evaluation of peri-implant bone level changes was conducted. Results: Thirty patients (20 females and 10 males) were followed up for an average of 44 months (range 18-67 months). Six patients received both upper and lower implant rehabilitations, resulting in 36 restorations. A total of two hundred two implants were placed (maxilla = 118; mandible = 84) and 46% of the fixtures were evaluated at the 4-year recall. Four axial implants were lost in three patients, leading to 98.02% implant (97.56% axial implants and 100% tilted implants) and 100% prosthetic cumulative survival rate, respectively. No significant difference in marginal bone loss was found between tilted and axial implants in both jaws at 1-year evaluation. Conclusions: Midterm results confirmed that immediate loading of axial and tilted implants provides a viable treatment modality for the rehabilitation of edentulous arches.
Article
Immediate-function Brånemark System® implants (Nobel Biocare AB, Gothenburg, Sweden) have become an accepted alternative for fixed restorations in edentulous mandibles, based on documented high success rates. Continuous development is ongoing to find simple protocols for their use. The purpose of this study was to develop and document a simple, safe, and effective surgical and prosthetic protocol for immediate function (within 2 hours) of four Brånemark System implants supporting fixed prostheses in completely edentulous mandibles: the “All-on-Four” concept. This retrospective clinical study included 44 patients with 176 immediately loaded implants, placed in the anterior region, supporting fixed complete-arch mandibular prostheses in acrylic. In addition to the immediately loaded implants, 24 of the 44 patients had 62 rescue implants not incorporated in the provisional prostheses but incorporated in final prostheses later on. Five immediately loaded implants were lost in five patients before the 6-month follow-up, giving cumulative survival rates of 96.7 and 98.2% for development and routine groups, respectively. The prostheses' survival was 100%, and the average bone resorption was low. The high cumulative implant and prostheses survival rates indicate that the “All-on-Four” immediate-function concept with Brånemark System implants used in completely edentulous mandibles is a viable concept.
Article
Background: Owing to mechanical and anatomic difficulties, implant treatment in the atrophic maxilla represents a challenge. The maxillary sinus floor augmentation procedure is still not universally accepted because of its complexity and its unpredictability. Purpose: In this study, a combination of tilted and axial implants was used in patients with severely resorbed posterior maxillae as an alternative to sinus grafting. Materials and Methods: Twenty-five patients were rehabilitated with 29 fixed partial prostheses supported by 101 Brånemark System implants. Fifty-nine implants were installed in an axial and 42 in a tilted direction. The average follow-up period was 37 months (range:21–87 mo post loading). Results: After 5 years, the implant cumulative success rate was 95.2% (survival: rate 100%) for the tilted implants and 91.3% (survival rate:96.5%) for the axial implants, and the prosthesis survival rate was 100%. At the fifth year, the average marginal bone loss was 1.21 mm for the tilted implants and 0.92 mm for the axial ones. The mean Periotest values (PTV) at loading time were -2.62 and -3.57, and after 5 years the PTVs were -4.73 and -5.00 for the tilted and the axial implants, respectively. During the follow-up, all prostheses but two were mechanically stable, retightening of 18 abutment screws and of 5 gold screws in 14 prostheses was done, and fracture of two abutment screws and two occlusal surfaces was experienced. Conclusions: Results indicate that the use of tilted implants is an effective and safe alternative to maxillary sinus floor augmentation procedures.
Article
A systematic review of the literature concerning upper airway imaging and analysis using cone-beam computed tomography (CBCT) was performed. A PubMed search (National Library of Medicine, NCBI; revised 9th January 2011) yielded 382 papers published between 1968 and 2010. The 382 full papers were screened in detail. 46 articles were considered clinically or technically relevant and were included in this systematic review. These were classified as articles on accuracy and reliability of CBCT imaging of the upper airway (n=4), accuracy and reliability of DICOM viewers (n=2), synopsis (n=10), technical (n=7) and clinical applications (n=27). When one paper was considered related to two or more categories, it was assigned to each relevant group. Results indicate that three-dimensional (3D) analysis of the upper airway using CBCT can be achieved in an accurate and reliable manner. Important obstacles still need to be addressed, including the impact of respiration phase, influence of tongue position and mandible morphology, longitudinal and cross-sectional 3D CBCT upper airway evaluation, and 3D CBCT definition of the anatomical boundaries of the upper airway.
Article
This study evaluated, through a systematic review of the literature, the estimated implant survival rate of short (<10 mm) dental implants installed in partially edentulous patients. A systematic search was conducted in the electronic databases of MEDLINE (1980-October 2009) and EMBASE (1980-October 2009) to identify eligible studies. Two reviewers independently assessed the methodological quality of the articles using specific study design-related quality assessment forms. Twenty-nine methodologically acceptable studies were selected. A total of 2611 short implants (lengths 5-9.5 mm) were analysed. An increase in implant length was associated with an increase in implant survival (from 93.1% to 98.6%). Heterogeneity between studies was explored by subgroup analyses. The cumulative estimated failure rate of studies performed in the maxilla was 0.010 implants/year, compared with 0.003 found in the studies in the mandible. For studies that also included smokers, the failure rate was 0.008 compared with 0.004 found in studies that excluded smokers. Surface topography and augmentation procedure were not sources of heterogeneity. There is fair evidence that short (<10 mm) implants can be placed successfully in the partially edentulous patient, although with a tendency towards an increasing survival rate per implant length, and the prognosis may be better in the mandible of non smoking patients.
Article
The aim of this study was to investigate the accuracy and reliability of linear measurements of edentulous ridges recorded from 16-row multidetector CT (MDCT) images and cone beam CT (CBCT) images acquired using a flat panel detector (FPD) with a large field of view (FOV), both independently and in comparison with each other. Edentulous areas of human dry skulls were marked with gutta-percha markers to standardize the plane of the transverse cross-sections and path of measurements. The skulls were imaged using a 16-row MDCT scanner and a CBCT device with a large FOV and a FPD. Ridge dimensions were recorded from reformatted sections by two observers and compared with measurements recorded directly from the bone. The measurement errors and intra and interexaminer reliability were calculated for each modality and compared with each other. The overall mean of the absolute errors was 0.75 mm for MDCT and 0.49 mm for CBCT. The mean of the CBCT absolute errors was smaller than that of the MDCT absolute errors for the overall data, as well as for the site-specific data. The intraexaminer reliability score was 0.994 for MDCT and 0.995 for CBCT. The interexaminer reliability was 0.985 for MDCT and 0.958 for CBCT. Both MDCT and CBCT were associated with a clinically and statistically significant measurement error. CBCT measurements were significantly more accurate than those of MDCT. The measurements recorded from both modalities had a high inter and intraexaminer reliability. Accuracy of measurements was found to be more operator dependent with CBCT than with MDCT.
Article
To evaluate whether 7-mm-long implants could be an alternative to longer implants placed in vertically augmented posterior mandibles. Sixty patients with posterior mandibular edentulism with 7-8 mm bone height above the mandibular canal were randomized to either vertical augmentation with anorganic bovine bone blocks and delayed 5-month placement of ≥10 mm implants or to receive 7-mm-long implants. Four months after implant placement, provisional prostheses were delivered, replaced after 4 months, by definitive prostheses. The outcome measures were prosthesis and implant failures, any complications and peri-implant marginal bone levels. All patients were followed to 1 year after loading. One patient dropped out from the short implant group. In two augmented mandibles, there was not sufficient bone to place 10-mm-long implants possibly because the blocks had broken apart during insertion. One prosthesis could not be placed when planned in the 7 mm group vs. three prostheses in the augmented group, because of early failure of one implant in each patient. Four complications (wound dehiscence) occurred during graft healing in the augmented group vs. none in the 7 mm group. No complications occurred after implant placement. These differences were not statistically significant. One year after loading, patients of both groups lost an average of 1 mm of peri-implant bone. There no statistically significant differences in bone loss between groups. When residual bone height over the mandibular canal is between 7 and 8 mm, 7 mm short implants might be a preferable choice than vertical augmentation, reducing the chair time, expenses and morbidity. These 1-year preliminary results need to be confirmed by follow-up of at least 5 years.
Article
Ideally, implants for dental prostheses should be placed parallel to each other. However, anatomic limitations sometimes make nonparallel implants necessary. The purpose of this study was to determine the bone stresses on implants tilted at various angles and to determine what arrangements might carry a higher risk of failure. Three-dimensional finite element models were constructed using the mean values measured for the Asian mandible in the first and second molar areas. Eight implants were divided into three tilting types: parallel implants (P1(PP), P2(MM), and P3(DD)), convergent implant apices (C1(PD) and C2(MP)), and divergent implant apices (D1(DP), D2(DM), and D3(PM)). A biting load of 200 N was applied vertically and obliquely on the occlusal central fossa of the splinted crowns. The main effects of each level of the three investigated factors (loading type, relationship of implant apices, and distal tilting of one or both implants) in terms of the stress values were computed for all models. The loading type was the main factor affecting the stress in bone when comparing implant apices and distal tilting of the implant body. When loading was combined with distal tilting, the stress values were significantly increased, especially in models P3(DD) and C1(PD). The loading type is the main factor affecting the stress distribution for different implantation arrangement. Moreover, placement of the implants with distal tilting should be avoided in the posterior mandible.
Article
Purpose: The aim of this review was to evaluate the survival rate of upright and tilted implants supporting fixed prosthetic reconstructions for the immediate rehabilitation of partially and fully edentulous jaws, after at least 1 year of function. Materials and Methods: An electronic search of databases plus a hand search on the most relevant journals up to December 2009 was performed. The articles were selected using specific inclusion criteria, independent of the study design. Results: The literature search yielded 347 articles. A first screening based on the title and abstract identified 25 eligible studies. After full-text review of these studies, 10 articles were selected for analysis. Seven were prospective single-cohort studies and three had a retrospective design. A total of 462 patients have been rehabilitated with 470 immediately loaded prostheses (257 in the maxilla, 213 in the mandible), supported by a total of 1,992 implants (1,026 upright and 966 tilted). Twenty-five implants (1.25%) failed in 20 patients within the first year. All failures except one occurred in the maxilla. No significant difference in failure rate was found between tilted and upright implants, nor between maxillary and mandibular implants. No prosthesis failure was reported. Limited peri-implant bone loss was reported with no difference between upright and tilted implants. Full patients' satisfaction for function, phonetics, and esthetics was reported in three studies, based on questionnaires. Conclusions: The use of tilted implants to support immediately loaded fixed prostheses for the rehabilitation of edentulous jaws can be considered a predictable technique, with an excellent prognosis in the short-medium term. However, randomized long-term trials are needed to determine the efficacy of this surgical approach.
Article
The purpose of this study was to prospectively evaluate the clinical and radiographic outcomes of immediately loaded full-arch fixed prostheses supported by a combination of axially and non-axially positioned implants in a large cohort of patients with completely edentulous jaws, up to 5 years of function. One hundred and seventy-three edentulous patients (80 males and 93 females) were enrolled according to specific selection criteria. Each patient received a full-arch fixed prosthesis supported by two distal tilted implants and two anterior axially placed implants. The provisional functional acrylic prosthesis was delivered the same day as surgery in all cases. All cases were finalized 4-6 months later. The patients were scheduled for follow-up at 6 and 12 months of function, and annually up to 5 years. At each follow-up plaque and bleeding score was assessed and radiographic evaluation of marginal bone level was performed. The overall follow-up range was 4-59 months. A total of 154 immediately loaded prostheses (61 in the maxilla and 93 in the mandible) were in function for at least 1 year and were considered for the analysis. Four axially placed implants failed in the maxilla and one tilted implant in the mandible, all within 6 months of loading. No further implant failure occurred to date. Implant survival at 1 year was 98.36% and 99.73% for the maxilla and the mandible, respectively. Marginal bone loss at 1 year averaged 0.9+/-0.7 mm in the maxilla (204 implants) and 1.2+/-0.9 mm in the mandible (292 implants). No difference was found in marginal bone loss between axial and tilted implants. Plaque and bleeding scores progressively improved from 6 to 12 months. Fracture of the acrylic prosthesis occurred in 14% of total cases. The present preliminary results from a relatively large sample size suggest that the present technique can be considered a viable treatment option for the immediate rehabilitation of both mandible and maxilla.
Article
To compare the diagnostic accuracy of intraoral digital periapical radiography with that of cone beam computed tomography (CBCT) for the detection of artificial periapical bone defects in dry human jaws. Small and large artificial periapical lesions were prepared in the periapical region of the distal root of six molar teeth in human mandibles. Scans and radiographs were taken with a charged couple device (CCD) digital radiography system and a CBCT scanner before and after each periapical lesion had been created. Sensitivity, specificity, positive predictive values, negative predictive values and Receiver Operator Characteristic (ROC) curves as well as the reproducibility of each technique were determined. The overall sensitivity was 0.248 and 1.0 for intraoral radiography and CBCT respectively, i.e. these techniques correctly identified periapical lesions in 24.8% and 100% of cases, respectively. Both imaging techniques had specificity values of 1.0. The ROC Az values were 0.791 and 1.000 for intraoral radiography and CBCT, respectively. With intraoral radiography, external factors (i.e. anatomical noise and poor irradiation geometry), which are not in the clinician's control, hinder the detection of periapical lesions. CBCT removes these external factors. In addition, it allows the clinician to select the most relevant views of the area of interest resulting in improved detection of the presence and absence of artificial periapical lesions.
Article
The use of shorter implants offers a number of potential advantages if such utilization yields the same level of treatment success as the use of longer implants. The purpose of this retrospective study was to assess the survival of short implants in various clinical situations in function over time. A retrospective study was conducted of all patients treated between May 2000 and May 2007 who received endosseous implants that were less than 10 mm in length. Patient age, gender, location of implants, type of prosthesis, time in function, and stability of peri-implant crestal bone were assessed. The retrospective analysis identified 2,073 implants of 6 mm, 7 mm, 8 mm, or 9 mm in length placed in a variety of clinical situations in 1,774 patients. Cumulative implant survival rates for implants in function in various areas of the mouth supporting single crowns or short-span fixed prostheses ranged from 98.1% to 99.7%. Each indication was examined with regard to individual success and failure rates and mean time in function. When utilized appropriately, implants of 6 to 9 mm in length demonstrate cumulative survival rates under function comparable to those reported for longer implants.
Article
This study presents the clinical results of a surgical technique that expands a narrow ridge when its orofacial width precludes the placement of dental implants. In 170 people, 329 implants were placed in sites needing ridge enlargement using the endentulous ridge expansion procedure. This technique involves a partial-thickness flap, crestal and vertical intraosseous incisions into the ridge, and buccal displacement of the buccal cortical plate, including a portion of the underiying spongiosa. Implants were placed in the expanded ridge and allowed to heal for 4 to 5 months. When indicated, the implants were exposed during a second-stage surgery to allow visualization of the implant site. Occlusal loading was applied during the following 3 to 5 months by provisional prostheses. The final phase was the placement of the permanent prostheses. The results yielded a success rate of 98.8%.
Article
Various lengths of cantilevers for fixed implant-supported prostheses have been recommended in the literature. No scientific data are available for selecting specific lengths, and different views are reported. Authors contend that longer cantilevers lead to increased risk of failure. This study examined survival of fixed implant-supported prostheses using different cantilever lengths and offers clinical support for the contention.
Article
The distribution of stress around implants placed in the first molar region of the mandible was biomechanically analyzed in a two-dimensional mathematical model. Two types of implants, vertical and angled, were subjected to a vertical load of 100 N and a horizontal load of 50 N in turn. The magnitudes and contours of compressive and tensile stress within the surrounding bone were determined. For the sake of comparison, maximal compressive stress and maximal tensile stress at the surrounding bone were calculated. There were no measurable differences in stress values and contours when a horizontal load was applied to the vertical and angled implants. However, with the vertical loading, the compressive stress values were five times higher around the cervical region of the angled implant than around the same area in the vertical implant.
Article
The American Academy of Oral and Maxillofacial Radiology (AAOMR) has reviewed the implant imaging literature and issues this position paper for preoperative assessment of the dental implant site. The history of dental implant radiology and basic imaging principles are reviewed. An overview is presented of anatomically salient features in the maxilla and mandible germane to implant imaging, specifically to cross-sectional or transverse imaging for endosseous implants. All current modalities, including intraoral, panoramic, cephalometric, tomographic, and computed tomography, are discussed in light of the imaging data needed to select optimum implant solutions. After reviewing the current literature, the AAOMR recommends that some form of cross-sectional imaging be used for implant cases and that conventional cross-sectional tomography be the method of choice for gaining this information for most patients receiving implants.
Article
The aim of this study was to retrospectively analyze whether the inclusion of cantilever extensions increased the amount of marginal bone loss at free-standing, implant-supported, fixed partial dentures (FPDs) over a 5-year period of functional loading. The patient material comprised 45 periodontally treated, partially dentate patients with a total of 50 free-standing FPDs supported by implants of the Astra Tech System. Following FPD placement (baseline) the patients were enrolled in an individually designed supportive care program. A set of criteria was collected at baseline to characterize the FPDs. The primary outcome variable was change in peri-implant bone level from the time of FPD placement to the 5-year follow-up examination. The comparison between FPDs with and without cantilevers was performed at three levels: FPD level, implant level, and surface level. Bivariate analysis was performed by the use of the Mann-Whitney U-test and stepwise regression analysis was utilized to evaluate the potential influence of confounding factors on the change in peri-implant bone level. The overall mean marginal bone loss for the implant-supported FPDs after 5 years in function was 0.4 mm (SD, 0.76). The bone level change at FPDs placed in the maxilla was significantly greater than that for FPDs in the mandible (0.6 versus 0.2 mm; p<0.05). No statistically significant differences were found with regard to peri-implant bone level change over the 5 years between FPDs with and without cantilevers at any of the levels of comparisons. The multivariate analysis revealed that the variables jaw of treatment and smoking had a significant influence on peri-implant bone level change on the FPD level, but not on the implant or surface levels. The model explained only 10% of the observed variance in the bone level change. The study failed to demonstrate that the presence of cantilever extensions in an FPD had an effect on peri-implant bone loss.
Article
Due to lack of the periodontal ligament, osseointegrated implants, unlike natural teeth, react biomechanically in a different fashion to occlusal force. It is therefore believed that dental implants may be more prone to occlusal overloading, which is often regarded as one of the potential causes for peri-implant bone loss and failure of the implant/implant prosthesis. Overloading factors that may negatively influence on implant longevity include large cantilevers, parafunctions, improper occlusal designs, and premature contacts. Hence, it is important to control implant occlusion within physiologic limit and thus provide optimal implant load to ensure a long-term implant success. The purposes of this paper are to discuss the importance of implant occlusion for implant longevity and to provide clinical guidelines of optimal implant occlusion and possible solutions managing complications related to implant occlusion. It must be emphasized that currently there is no evidence-based, implant-specific concept of occlusion. Future studies in this area are needed to clarify the relationship between occlusion and implant success.
Article
Immediate implant function has become an accepted treatment modality for fixed restorations in totally edentulous mandibles, whereas experience from immediate function in the edentulous maxilla is limited. The purpose of this study was to evaluate a protocol for immediate function (within 3 hours) of four implants (All-on-4, Nobel Biocare AB, Göteborg, Sweden) supporting a fixed prosthesis in the completely edentulous maxilla. This retrospective clinical study included 32 patients with 128 immediately loaded implants (Brånemark System TiUnite, Nobel Biocare AB) supporting fixed complete-arch maxillary all-acrylic prostheses. A specially designed surgical guide was used to facilitate implant positioning and tilting of the posterior implants to achieve good bone anchorage and large interimplant distance for good prosthetic support. Follow-up examinations were performed at 6 and 12 months. Radiographic assessment of the marginal bone level was performed after 1 year in function. Three immediately loaded implants were lost in three patients, giving a 1-year cumulative survival rate of 97.6%. The marginal bone level was, on average, 0.9 mm (SD 1.0 mm) from the implant/abutment junction after 1 year. The high cumulative implant survival rate indicates that the immediate function concept for completely edentulous maxillae may be a viable concept.
Article
Posterior maxillae are often difficult to treat owing to the sinus antrum. Placing implants in remaining bone regions in the atrophic maxilla, without performing sinus grafting, is a challenge. Immediate function adds to this challenge. The purpose of this study was to suggest and evaluate a simplified treatment concept for the rehabilitation of the atrophic maxilla using tilted implants subjected to immediate/early function. Eighteen patients were included in the study. Sixty implants were placed to support 19 fixed partial or full-arch prostheses. Immediate/early function was applied. The patients were followed for a minimum of 1 year after prosthesis connection. Stability measurements and radiographic evaluation of the change of the marginal bone level were performed. One axial and one tilted implant failed in one patient, giving a cumulative survival rate of 96.7%. No failure of provisional prostheses occurred. The mean marginal bone resorption recorded after 1 year was low (0.82 mm for axial implants and 0.34 mm for tilted implants). The results of the present study suggest that tilted implants placed in immediate function may be a viable treatment approach for the rehabilitation of the atrophied maxilla. Simplified treatment procedures, reduced surgical invasion, shorter treatment time, and reduced costs constitute some of the benefits for the patient and the clinician.
Article
Despite the high success rates of endosseous oral implants, restrictions have been advocated to their placement with regard to the bone available in height and volume. The use of short or nonstandard-diameter implants could be one way to overcome this limitation. In order to explore the relationship between implant survival rates and their length and diameter, a Medline and a hand search was conducted covering the period 1990-2005. Papers were included which reported: (1) relevant data on implant length and diameter, (2) implant survival rates; either clearly indicated or calculable from data in the paper, (3) clearly defined criteria for implant failure, and in which (4) implants were placed in healed sites and (5) studies were in human subjects. A total of 53 human studies fulfilled the inclusion criteria. Concerning implant length, a relatively high number of published studies (12) indicated an increased failure rate with short implants which was associated with operators' learning curves, a routine surgical preparation (independent of the bone density), the use of machined-surfaced implants, and the placement in sites with poor bone density. Recent publications (22) reporting an adapted surgical preparation and the use of textured-surfaced implants have indicated survival rates of short implants comparable with those obtained with longer ones. Considering implant diameter, a few publications on wide-diameter implants have reported an increased failure rate, which was mainly associated with the operators' learning curves, poor bone density, implant design and site preparation, and the use of a wide implant when primary stability had not been achieved with a standard-diameter implant. More recent publications with an adapted surgical preparation, new implant designs and adequate indications have demonstrated that implant survival rate and diameter have no relationship. When surgical preparation is related to bone density, textured-surfaced implants are employed, operators' surgical skills are developed, and indications for implant treatment duly considered, the survival rates for short and for wide-diameter implants has been found to be comparable with those obtained with longer implants and those of a standard diameter. The use of a short or wide implant may be considered in sites thought unfavourable for implant success, such as those associated with bone resorption or previous injury and trauma. While in these situations implant failure rates may be increased, outcomes should be compared with those associated with advanced surgical procedure such as bone grafting, sinus lifting, and the transposition of the alveolar nerve.
Article
The aim of this study was to retrospectively analyze the potential influence of implant inclination on marginal bone loss at freestanding, implant-supported, fixed partial dentures (FPDs) over a 5-year period of functional loading. The material comprised 38 periodontally treated, partially dentate patients with a total of 42 free-standing FPDs supported by implants of the Astra Tech System. Mesio-distal inclination of the implants in relation to a vertical axis perpendicular to the occlusal plane was measured with a protractor on standardized photographs of the master cast. The two tail quartiles of the distribution of the implants with regard to the implant inclination were defined as axial-positioned (mean 2.4 degrees; range 0-4 degrees) and non-axial-positioned implants (mean 17.1 degrees; range 11-30 degrees), respectively. For FPDs supported by two implants, both the mesial-distal and buccal-lingual inter-implant inclination was measured. The primary outcome variable was change in peri-implant bone level from the time of FPD placement to the 5-year follow-up examination. Comparison between axial- and non-axial-positioned implants was performed by the use of a Mann-Whitney U-test. Spearman's correlation analysis was used to analyze relationships between inter-implant inclination (mesial-distal and buccal-lingual) and 5-year bone level change on the FPD level. The 5-year mean bone level change amounted to 0.4 mm (SD 0.97) for the axial and 0.5 mm (0.95) for non-axial-positioned implants (P>0.05). For the FPDs supported by two implants, the mean inter-implant inclination was 9.2 degrees (1-36 degrees) in the mesial-distal direction and 6.7 degrees (0-24 degrees) in the buccal-lingual direction. Correlation analysis revealed lack of statistically significant correlation between inter-implant inclination (mesial-distal and buccal-lingual) and 5-year bone level change (r=-0.19 and r=-0.32, respectively). The study failed to support the hypothesis that implant inclination has an effect on peri-implant bone loss.
Evaluation of diagnostic accuracy of conventional and digital periapical radiography, panoramic radiography, and cone-beam computed tomography in the assessment of alveolar bone loss
  • W M Takeshita
  • L C Vessoni Iwaki
  • Da Silva
  • M C Tonin
Takeshita WM, Vessoni Iwaki LC, Da Silva MC, Tonin RH. Evaluation of diagnostic accuracy of conventional and digital periapical radiography, panoramic radiography, and cone-beam computed tomography in the assessment of alveolar bone loss. Contemp Clin Dent 2014; 5:318-323.
Computer-aided design evaluation of harvestable mandibular bone volume: A clinical and tomographic human study
  • F Verdugo
  • K Simonian
  • L Raffaelli
  • D Addona
Verdugo F, Simonian K, Raffaelli L, D'Addona A. Computer-aided design evaluation of harvestable mandibular bone volume: A clinical and tomographic human study. Clin Implant Dent Relat Res 2014;16:348-355.