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Pupil Reactivity to Emotional Faces Among Convicted Violent Offenders: The Role of Psychopathic Traits

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Psychopathy is characteristically associated with impairments in recognizing others' facial expressions of emotion, and there is some evidence that these difficulties are specific to the callousness features of the disorder. However, it remains unclear whether these difficulties are accompanied by reductions in autonomic reactivity when viewing others' emotional expressions, and whether these impairments are particular to expressions showing another's distress or are more pervasive across different emotional expressions. In this study, 73 adult male prisoners with histories of serious sexual or violent offenses-who ranged across the psychopathy continuum-completed a facial emotion recognition task. For the first time in a convicted offender sample, we used pupillometry techniques to measure changes in the pupil dilation response, a measure of sympathetic autonomic arousal to affective stimuli. We found that the callousness features of psychopathy were related to impaired recognition of fearful faces. Strikingly, we also showed that increasing callousness was associated with a reduction in the pupil dilation response and that this was pervasive across different emotional expressions. Our results highlight a potential role of the locus coeruleus-noradrenaline system in the pathophysiology of psychopathy and demonstrate the potential of the pupillary response as a technique for understanding attention-emotion interactions in psychopathy. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
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Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
1
Pupil reactivity to emotional faces among convicted violent offenders:
The role of psychopathic traits
Steven M. Gillespie1, Pia Rotshtein2, Harriet Chapman2,
Emmie Brown3, Anthony R. Beech2, Ian J. Mitchell2
1Department of Psychological Sciences, University of Liverpool, UK
2School of Psychology, University of Birmingham, UK
3School of Psychology, Newcastle University, UK
Citation: Gillespie, S. M., Rotshtein, P., Chapman, H., Brown, E., Beech, A. R., & Mitchell, I. J.
(2019, July 18). Pupil reactivity to emotional faces among convicted violent offenders: The role of
psychopathic traits. Journal of Abnormal Psychology. Advance online publication.
http://dx.doi.org/10.1037/abn0000445
Author Note
This work was funded by a grant from the Economic and Social Research Council (ESRC)
[ES/L002337/1]. The funder had no role in study design; in the collection, analysis, and interpretation
of data; in the writing of the report; and in the decision to submit the article for publication.
Ethical approval for this study was granted by the University of Birmingham Committee for
Ethical Review for Science, Technology, Engineering and Mathematics (ERN_ 15-0600P).
Hypotheses and data appearing in this manuscript have not previously been presented at a
conference, or shared on a website etc.
Correspondence concerning this article should be addressed to: Steven M. Gillespie,
Department of Psychological Sciences, University of Liverpool, UK, L69 3GB, email:
steven.gillespie@liverpool.ac.uk
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
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Abstract
Psychopathy is characteristically associated with impairments in recognizing others facial expressions
of emotion, and there is some evidence that these difficulties are specific to the callousness features of
the disorder. However, it remains unclear if these difficulties are accompanied by reductions in
autonomic reactivity when viewing others emotional expressions, and whether these impairments are
particular to expressions showing another’s distress, or are more pervasive across different emotional
expressions. In this study, 73 adult male prisoners with histories of serious sexual or violent offenses
who ranged across the psychopathy continuum completed a facial emotion recognition task. For
the first time in a convicted offender sample, we used pupillometry techniques to measure changes in
the pupil dilation response, a measure of sympathetic autonomic arousal to affective stimuli. We
found that the callousness features of psychopathy were related to impaired recognition of fearful
faces. Strikingly, we also showed that increasing callousness was associated with a reduction in the
pupil dilation response, and that this was pervasive across different emotional expressions. Our results
highlight a potential role of the locus coeruleus-noradrenaline system in the pathophysiology of
psychopathy, and demonstrate the potential of the pupillary response as a technique for understanding
attention-emotion interactions in psychopathy.
Key words: psychopathy, fear, facial expression, pupilometry, antisocial behaviour
General scientific summary
We found that psychopathic traits among convicted violent offenders are associated with reduced
fearful expression recognition, and reduced arousal in response to the emotional expressions of others.
This study suggests that these difficulties may represent a mechanism for the callousness features of
psychopathy.
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
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Pupil reactivity to emotional faces among convicted violent offenders:
The role of psychopathic traits
Convicted psychopaths account for more severe and more frequent acts of aggression, and
they engage in instrumental forms of aggression at a higher rate than non-psychopaths do (Skeem,
Polaschek, Patrick, & Lilienfeld, 2011). These behaviours are thought to reflect deficiencies in
emotion processing, and reduced reactivity of the autonomic nervous system [ANS] to emotional
stimuli (Blair, Leibenluft, & Pine, 2014; Fanti, 2018). Psychopathy is a multidimensional construct
that is characterized by callous/affective (e.g., lack of remorse or guilt, shallow affect), interpersonal
(e.g., manipulative, interpersonal charm), and behavioral (e.g., recklessness, impulsivity)
characteristics (Cooke & Michie, 2001; Patrick, Fowles, & Krueger, 2009). It is hypothesized that the
callousness features are related to both emotional reactivity deficits (e.g., Kyranides, Fanti, Sikki, &
Patrick, 2017), and a diminished ability to recognize and respond to other’s emotional facial
expressions (Blair et al., 2014). However, whether these difficulties are specific to expressions
signalling another’s distress, or are more generalized across different emotional expressions, has been
the subject of some debate (Brook, Brieman, & Kosson, 2013; Dawel, O'Kearney, McKone, &
Palermo, 2012). The aims of the present study were to assess the relationship of distinct psychopathic
traits with accuracy of emotion recognition and autonomic reactivity to distress (fear, sad) and non-
distress (disgust, happy) facial expressions in a sample of convicted violent offenders.
Historically, psychopathy has been conceptualized and measured according to a two-
factor/four-facet model, with Factor 1 indexing Interpersonal and Affective features, and Factor 2
indexing Lifestyle and Antisocial features (Hare, 2003). These features can be measured in forensic
samples using the interview-based Psychopathy Checklist Revised (Hare, 2003). Alternatively, the
Triarchic Model of psychopathy conceptualizes the construct along three core dimensions, namely
Boldness, Meanness, and Disinhibition (Patrick et al., 2009). These trait dimensions have been
reliably identified and distinguished in forensic and non-forensic samples, and have been
operationalized using the Triarchic Psychopathy Measure (TriPM; Drislane, Patrick, & Arsal, 2014).
Boldness refers to venturesomeness, fearlessness, and interpersonal dominance (Patrick et al., 2009),
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
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and is positively associated with interpersonal features assessed using the Fearless Dominance
subscale of the Psychopathic Personality Inventory (PPI; Lilienfeld & Andrews, 1996; Lilienfeld &
Widows, 2005), and with PCL-R Interpersonal and Antisocial symptoms (Patrick & Drislane, 2015).
Meanness indexes callous and affective features, and is positively related to scores on the Inventory of
Callous-Unemotional Traits (ICU; Kimonis, Branch, Hagman, Graham, & Miller, 2013), the
Coldheartedness subscale of the PPI , and with PCL-R Affective and Antisocial symptoms (see
Patrick & Drislane, 2015 for a review). Moderate associations of Meanness with PPI Fearless
Dominance and Impulsive Antisociality features have also been reported (Patrick & Drislane, 2015).
Disinhibition refers to impulse control problems, emotional reactivity, and poor behavioural restraint
(Patrick et al., 2009). Patrick and Drislane (2015) have highlighted positive associations of
Disinhibition with PPI Impulsive Antisociality, and with PCL-R Lifestyle and Antisocial symptoms.
Thus, although Boldness, Meanness, and Disinhibition appear to be preferentially associated with
interpersonal, affective, and antisocial features, respectively, all three subscales have been linked with
higher PCL-R Antisocial symptoms.
The ways in which Boldness, Meanness, and Disinhibition relate to measures of emotion
processing and ANS reactivity remain unclear. Although several prominent accounts of psychopathy
emphasize difficulties in emotional expression recognition (Blair et al., 2014; Moul, Killcross, &
Dadds, 2012), there is some debate as to whether these deficits are particular to emotions signalling
another’s distress, most notably fear and sadness, or are more generalized across the emotional
spectrum, including, for example, anger, disgust and happy (Brook & Kosson, 2013; Dawel et al.,
2012). The callousness dimension in particular appears to be linked with difficulties recognizing
others’ distress from their emotional expressions (Brislin et al., 2018; Dargis, Wolf, & Koenigs, 2018;
Gillespie, Mitchell, Satherley, Beech, & Rotshtein, 2015; Igoumenou, Harmer, Yang, Coid, & Rogers,
2017), and is associated with amygdala hypoactivity to fearful facial expressions (Jones, Laurens,
Herba, Barker, & Viding, 2009; Viding et al., 2012; White et al., 2012). In contrast, the interpersonal
dimension is associated with a pattern of reduced attention to the eyes that is generalized across
different emotional expressions (Dargis et al., 2018; Gillespie, Rotshtein, Beech, & Mitchell, 2017;
Gillespie, Rotshtein, Wells, Beech, & Mitchell, 2015). As such, there are several important questions
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
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that require further clarification, including whether psychopathy related impairments in facial affect
recognition are specific to fear and sadness, or are more generalized across the emotional spectrum;
whether these impairments are primarily related to the callousness features of the disorder; and
whether these impairments are accompanied by hypoautonomic reactivity while viewing emotional
expressions.
ANS activity can be measured at rest, or in response to emotional stimuli. In both contexts,
psychopathy is associated with attenuated ANS responses (see De Brito & Mitchell, 2018 for a
review). In studies with convicted offenders, psychopathy has been linked with low resting heart rate
(Armstrong, Keller, Franklin, & Macmillan, 2009; Arnett, Howland, Smith, & Newman, 1993;
Patrick, 2008; Pham, Philippot, & Rime, 2000), and low resting levels of electrodermal activity
(Lorber, 2004). Studies of ANS reactivity in response to emotional stimuli have also shown that
psychopathy is related to reduced cardiovascular (Arnett et al., 1993; Ishikawa, Raine, Lencz, Bihrle,
& Lacasse, 2001; Patrick, 2008; Pham et al., 2000), and electrodermal reactivity (Arnett, 1997;
Patrick, 2008; Rothemund et al., 2012), and an absence of, or reduction in, aversive startle
potentiation that is, the augmentation of the blink startle reflex that is normally observed in response
to an aversive stimulus (e.g., an unpleasant picture) (Pastor, Molto, Vila, & Lang, 2003; Patrick,
Bradley, & Lang, 1993).
In children with conduct problems, reductions in ANS activity, both at rest, and in response to
emotionally salient stimuli, are related to the callousness dimension in particular (Fanti, 2018).
Studies with adult community and offender samples have found negative associations of estimated
scores on PPI Fearless Dominance (Benning, Patrick, & Iacono, 2005), and PCL-R Interpersonal
symptoms (Verona, Patrick, Curtin, Bradley, & Lang, 2004), with electrodermal responsivity to
negative stimuli, and PPI Fearless Dominance is negatively associated with electrodermal responses
during anticipatory stress (Dindo & Fowles, 2011). Aversive startle potentiation is also inversely
related to estimated scores on PPI Fearless Dominance (Benning et al., 2005), and PCL-R Factor 1
(Vaidyanathan, Hall, Patrick, & Bernat, 2011), but is either unrelated (Benning et al., 2005;
Vaidyanathan et al., 2011), or positively related (Vanman, Mejia, Dawson, Schell, & Raine, 2003), to
impulsive and antisocial features. Consistent with these findings, TriPM Boldness was associated with
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
6
reduced cardiac reactivity to violent stimuli, while Meanness was associated with low startle
potentiation in a young adult sample (Kyranides et al., 2017). Thus, reduced ANS reactivity in
psychopathy appears to be most strongly associated with Boldness and Meanness.
Pupil dilation (pupilometry) is another marker of ANS reactivity that is sensitive to emotional
content, yet pupillary responses to emotional expressions have not been studied in convicted offender
samples. The smooth muscles involved in the pupil response are controlled by the two opposing
branches of the ANS: the dilator muscle, influenced by activity of the sympathetic nervous system
(SNS), and the sphincter muscle, influenced by activity of the parasympathetic nervous system (PNS).
Thus, pupil size reflects the relative activation of these two systems, with pupil dilation resulting from
either increased SNS activity, or reduced PNS activity.
Accumulating evidence suggests that the pupil dilation response is a robust marker of activity
in the locus coeruleus (LC) (Joshi, Li, Kalwani, & Gold, 2016; Murphy, O'Connell, O'Sullivan,
Robertson, & Balsters, 2014). LC neurons respond to the salience and biological significance of
stimuli, and give rise to the release of noradrenalin (i.e., norepinephrine), the neurotransmitter that
characterises sympathetic efferents. This release of noradrenaline is thought to facilitate the functional
integration of brain regions involved in attention (Corbetta, Patel, & Shulman, 2008; Coull, Buchel,
Friston, & Frith, 1999; Sara, 2009). Although no known anatomical pathways allow for a direct
influence of LC on the autonomic nuclei controlling pupil diameter (Nieuwenhuis, De Geus, & Aston‐
Jones, 2011), this tight relationship likely reflects parallel activation of the LC and SNS by sources of
common input. A likely candidate is the rostral ventrolateral medulla, a major excitatory input to the
LC, and a key sympathoexcitatory brain region that receives cortical and subcortical inputs
(Nieuwenhuis et al., 2011). While activation of the LC leads to noradrenergic release into the
neocortex, parallel activation of the SNS causes direct activation of the pupil dilator muscle. Thus, the
pupil dilation response represents a novel avenue of enquiry that could be revealing about a potential
role of the LC-noradrenaline system in the pathophysiology of psychopathy.
In community adult samples, increased pupil dilation has been observed in response to both
positive and negative stimuli (Bradley, Miccoli, Escrig, & Lang, 2008; Rieger et al., 2015; Snowden
et al., 2016), including emotional faces, particularly those depicting threat (i.e., fear and anger)
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
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(Schrammel, Pannasch, Graupner, Mojzisch, & Velichkovsky, 2009). Only one study has examined
pupil reactivity to emotional stimuli as a function of psychopathic tendencies in non-offenders
(Burley, Gray, & Snowden, 2017). Independent of psychopathic tendencies, this study replicated
previous reports showing that pupil dilation is increased for negative compared with neutral stimuli,
although no differences were reported for positive stimuli. More importantly, the authors did not
observe significant relationships of distinct psychopathic trait dimensions with pupillary responses to
any of the emotional stimuli (Burley et al., 2017). However, this null result may reflect the relatively
lower levels of psychopathic tendencies found in non-offender samples.
The Present Study
The aim of this study was to examine the relationship of distinct psychopathic traits with
recognition accuracy and pupillary responses to varied emotional expressions in a convicted offender
sample. We assessed three core dimensions of psychopathy, namely Boldness, Meanness, and
Disinhibition, described in the Triarchic conceptual framework (Patrick et al., 2009). Finally, we also
measured State and Trait anxiety because negative affect is an important factor regarding
heterogeneity in psychopathy (Hicks & Patrick, 2006; Kimonis, Frick, Cauffman, Goldweber, &
Skeem, 2012).
We predicted that Meanness would be negatively related to accuracy of emotional expression
recognition, and more pertinently, to autonomic reactivity indexed by the pupillary response.
Competing theories of the emotional deficits associated with psychopathy would predict that these
effects would either be specific to expressions of sadness and fear, or would be observed more
generally across the emotional spectrum (see Brook et al., 2013). Thus, as a test of both theories we
included a varied set of emotional expressions, depicting anger, disgust, fear, happy, sad, surprise, and
neutral. Expressions (excluding neutral) were presented at varying degrees of stimulus intensity to
provide more lifelike representations of emotional expressions, and to make the task more sensitive to
subtle differences in emotion processing (Adolphs & Tranel, 2004; Calder et al., 1996). Furthermore,
results suggest that psychopathy primarily affects the processing of moderate intensity expressions
(Hastings, Tangney, & Stuewig, 2008). In line with previous findings (Brook et al., 2013; Dawel et
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
8
al., 2012), we hypothesized that relationships of Meanness with accuracy and pupil reactivity would
be pervasive across expressions, but with the largest effect sizes observed for fear.
Method
Ethical Approval
Ethical approval for this study was obtained from the University of Birmingham Committee
for Ethical Review and the National Offender Management Service for England and Wales. We
informed potential participants that their acceptance or refusal to take part would have no bearing
upon their sentencing, treatment, or parole decisions. All participants were informed of their right to
withdraw their data within two weeks of participation, were provided with an information sheet,
signed an informed consent form, and were debriefed following participation.
Participants
A sample of 73 adult males aged 21-72 years (M = 38.7, SD = 11.7) who were incarcerated at
one of two Category B prisons in the United Kingdom took part in the study. Individuals were eligible
to take part if they were over the age of 18, and had been convicted of a violent offense, defined as
“any criminal charge for a violent offence against persons e.g., assault, assault causing bodily harm,
wounding, attempted homicide, homicide, kidnapping, forcible confinement, armed robbery, and all
‘hands-on’ sexual offences” (Harris, Rice, & Cormier, 2002, p. 383). Based on file information, no
participants had a diagnosis of schizophrenia, bipolar disorder or psychosis, and no participants were
currently using psychotropic medication. Three participants in the violent offender sample had a
history of post-traumatic stress disorder, three had a history of depression, and one had a history of
dissociative disorder. Recruitment in prison settings followed local procedures and included contact
with offender-supervisors, searching the prisons electronic database, and poster advertising. One
setting ran a research advisory group that consisted of expert-by-experience representatives from
eligible wings who took part in a question and answer session with two of the researchers. Wing
representatives aided recruitment on their own wings following this meeting. Most participants were
white Caucasian (86%). All participants had normal or corrected-to-normal vision.
For comparison purposes, we also recruited a sample of 25 community males. Because the
focus of this paper is on the relationship of psychopathic traits with pupil dilation responses in a
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
9
convicted offender sample, we present details of the community sample and comparisons between
groups in Supplemental Materials 1.
Accuracy data for a sub-sample of the offenders (n = 30) and for the control group have
previously been reported as part of a study on eye movements (Gillespie et al., 2017).
Materials
Facial expression stimuli. We used a subset of the morphed facial stimuli developed by
Gillespie and colleagues (Gillespie, Mitchell, et al., 2015; Gillespie, Rotshtein, Satherley, Beech, &
Mitchell, 2015; Gillespie, Rotshtein, Wells, et al., 2015; Wells, Gillespie, & Rotshtein, 2016).
Original stimuli were selected from the NimStim Face Stimulus Set (Tottenham et al., 2009;
http://www.macbrain.org/resources.htm) and consisted of five male and five female Caucasian models
showing seven different expressions: neutral, angry, disgust, fear, happy, sad, and surprise. Emotional
and neutral images from the same model were morphed to create images of varying levels of
emotional intensity (for details of the morphing procedure see Gillespie, Rotshtein, Satherley, et al.,
2015). Images used in the current study consisted of each emotion, for each model, displayed at
moderate (55% expressive) and high (90% expressive) intensity. Neutral stimuli were displayed at
100% neutral (i.e., neutral stimuli did not vary in intensity). Stimuli had a resolution of 504 x 624
pixels. The positioning of each image on the canvas was manipulated such that the eyes and the
mouth appeared in the same location across all stimuli. There were no differences in contrast (F(5,
108) = .153, p = .979) or luminance (F(5, 108) = .214, p = .956) as a function of emotional
expression. Contrast values were greater for images showing higher intensity expressions (F(1, 108) =
15.161, p < .001), but there were no differences in luminance (F(1, 108) = .783, p = .378). Given that
our main aim was to examine individual differences in pupil reactivity to the stimuli, we kept the
original contrast of the stimuli to maintain more life-like expressions, and to facilitate ecological
validity.
Measures. The Triarchic Psychopathy Measure (TriPM; Drislane et al., 2014) was used for
the assessment of psychopathic traits. This 58-item self-report measure yields scores on three
subscales: Boldness, Meanness, and Disinhibition. The TriPM Boldness scale includes items
assessing interpersonal dominance, venturesomeness, and fearlessness (Patrick et al., 2009).
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
10
Callousness was assessed using the Meanness scale and entails callous-aggressiveness, lack of
empathy, and a tendency toward exploiting others (Brislin et al., 2018; Drislane et al., 2014). TriPM
Disinhibition indexes impulsivity, emotional reactivity, and irresponsibility (Patrick et al., 2009).
Participants responded on a 4-point Likert scale (3 = true, 2 = somewhat true, 1 = somewhat false, 0 =
false). Internal consistencies for the Boldness, Meanness, and Disinhibition subscales in the convicted
offender sample were adequate: Cronbach’s ɑ = .68, .92, and .89, respectively. Participants in the
violent offender group also completed the State Trait Anxiety Inventory (STAI; Spielberger, 1983),
which contains both State [STAI-S] and Trait [STAI-T] subscales. Internal consistencies for the
STAI-S and STAI-T were good: Cronbach’s ɑ = .93, .93. One participant in the violent offender
group failed to complete the TriPM, and one participant failed to complete the STAI. Participants in
the community sample were also asked to complete the TriPM for comparison, although two
participants failed to complete the measure.
Pupillometry
We used an EyeLink 1000 corneal-reflection based portable eye tracking system (SR
Research Ltd.) to record participants’ pupil size. Although viewing was binocular, only pupil diameter
of the right eye was recorded. Pupil size was sampled at 1000 Hz. We used a Dell Precision laptop
computer to manage the recording of pupil diameter. Stimuli were displayed on a 19” LG colour
monitor, using SR-Research Experiment Builder software, running on a laptop computer with a
separate mouse and keyboard.
Procedure
Offender participants were tested in a private room inside the prison, whereas community
participants were tested in a dedicated eye-tracking laboratory at the university. Participants sat at a
desk with a chin rest of adjustable height to minimize head movements. Participants were positioned
approximately 68 cm from the display monitor, and images were presented at a visual angle of 21.2°.
Participants categorized the emotional expression stimuli as quickly and accurately as possible while
pupil size was being recorded. Standard EyeLink calibration and validation procedures were
performed, each using a series of nine fixation points. Facial expression stimuli were presented in a
randomized order over four blocks using the EyeLink software. At the start of each trial the
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
11
experimenter confirmed that the participant’s eye gaze fell on a fixation point presented in the centre
of the screen. A fixation cross was then presented for 1000 ms, followed by an image of an emotional
expression that was displayed for 2000 ms. Following display of the target expression, participants
categorized the facial expression using the numeric keys 0-6. Expression labels were displayed in a
vertical list alongside the relevant number key (e.g., 0. NEUTRAL).
Data Analysis
Accuracy data were analyzed as the proportion of correct responses for each stimulus
category (i.e., each emotion category at each level of intensity). To control for individual differences
in pupil size, and therefore expected differences in the degree of pupil change, we calculated within
participant percent change difference scores for each stimulus category (see Attard-Johnson, Ó
Ciardha, & Bindemann, 2018). First, for each trial we averaged pupil size across each individual
fixation for the duration of the stimulus display. We then used these values to calculate an overall
mean pupil size for each participant, across all trials. The percentage difference in pupil diameter for
each stimulus category compared to the overall mean was calculated using the following formula:
∆𝑃𝑖𝑐 =(𝑥̅𝑖𝑐 𝑥̅𝑒)
𝑥̅𝑒
100
𝑥̅𝑖𝑐 denotes the mean change for a specific category and intensity, and 𝑥̅𝑒 denotes the mean
response to all conditions, ∆𝑃𝑖𝑐 denotes the overall change in pupil diameter for a specific emotion
category (c) and intensity (i) compared to the overall mean. Thus, no change in pupil size is indicated
by zero, while positive or negative scores reflect relatively larger (dilation) or smaller (constriction)
pupil sizes in response to each stimulus category. The use of percentage change data performs as well
as other methods for the analysis of pupillary response data, including raw scores and z-scored data,
and better than pre-stimulus baseline correction where carryover effects have been observed (Attard-
Johnson et al., 2018). Second, to ensure that the observed changes in pupil size were due to changes in
the emotional content of expressions, we contrasted percentage change in pupil size for each stimulus
category with percentage change for neutral expressions (see Attard-Johnson et al., 2018). To do this,
we subtracted the percentage change in pupil size for neutral expressions from the percentage change
in pupil size for each stimulus category.
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
12
To understand the effects of the emotional content of the expression, expression intensity, and
the effects of self-reported psychopathic traits, we computed separate ANCOVAs for accuracy and
pupil reactivity. Each ANCOVA included the factors Emotion (anger, disgust, fear, happy, sad,
surprise), and Intensity (55%, 90%), with scores for Boldness, Meanness, and Disinhibition included
as covariates. Significant interactions were broken down using subsequent ANCOVAs. To test if any
effects of psychopathic traits were due to severity of antisocial behavior, ANCOVAs on accuracy and
pupil reactivity were repeated with total number of previous convictions for violence included as an
additional covariate. Supplementary ANCOVAs on accuracy and pupil reactivity were also performed
including a community control group, and with State and Trait Anxiety included separately as
covariates. Analyses including State and Trait Anxiety allowed us to test for the effects of negative
affect without controlling for important aspects of the psychopathy construct. The results of these
supplementary analyses are reported in Supplemental Materials 1 and 2, respectively. As Age was
unrelated to either accuracy of expression recognition (all r < .12 and ≥ -.23, p > .05), or pupil dilation
responses (all r < .19 and > -.07, p > .12), we did not include Age as a covariate.
Results
Table 1.
Sample description and correlations between measures in convicted violent offenders, community
non-offenders, and descriptive statistics reported by van Dongen et al. (2017) for community (N =
385), and forensic psychiatric samples (N = 296)
Variable
Bold.
Mean.
Disin.
STAI-S
STAI-T
Age
Previous
convictions
for violencea
TriPM Meanness
.206
-
TriPM Disinhibition
-.007
.616**
-
STAI-S
-.266*
-.124
-.060
-
STAI-T
-.316*
.112
.169
.729**
-
Age
-.185
-.081
-.134
-.032
-.012
-
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
13
Previous convictions
for violencea
-.072
.237*
.355*
-.050
-.020
.005
-
Range
11-44
0-50
0-54
20-66
20-73
21-72
0-14
Mean
28.5
14.2
28.4
32.3
42.7
38.7
2.3
Median
28
11
30
29
43
36
1
SD
7.9
11.3
13.3
11.0
11.8
11.7
3.3
Range
9-47
2-38
2-42
18-69
Mean
28.9
13.4
17.7
37.9
Median
28
9
17
31
SD
9.0
9.8
10.5
18.3
Community Meanb
31.1
12.3
11.5
Community SDb
8.14
7.8
7.8
Forensic Meanc
30.6
16.1
26.7
Forensic SDc
9.2
9.6
12.0
* <.05, ** <.001
Note: TriPM = Triarchic Psychopathy Measure; STAI-S = State Trait Anxiety Inventory State;
STAI-T = State Trait Anxiety Inventory Trait.
a Previous convictions for violence excludes index offense.
b Scores reported by van Dongen et al. (2017) for a community sample (N=496)
c Scores reported by van Dongen et al. (2017) for a forensic psychiatric sample (N=296)
Table 1 shows mean scores and standard deviations for all self-report measures completed by
violent offenders, along with the correlations between measures. For comparison, descriptive statistics
for the TriPM subscales in the community sample are also included, as well as published comparison
scores from community (N = 496), and forensic psychiatric samples (N = 296) (van Dongen, Drislane,
Nijman, Soe-Agnie, & van Marle, 2017). TriPM scores among violent offenders were similar to those
reported by van Dongen et al. (2017) for a separate sample of forensic psychiatric patients, while
Meanness and Disinhibition scores were higher compared with community controls in this study, and
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
14
community participants reported by van Dongen and colleagues. Meanness and Disinhibition were
positively correlated among violent offenders, while Boldness was unrelated to either Meanness or
Disinhibition, but was negatively correlated with measures of negative affect. Meanness and
Disinhibition were associated with a greater number of previous convictions for violence. Table 2
shows accuracy of emotion recognition and percent changes in pupil size for convicted violent
offenders as a function of Emotion and Intensity.
Table 2.
Mean task performance for violent offenders (n=73)
Accuracy
Pupil reactivity
Emotion
Intensity
M (SD)
M (SD)
Anger
55%
.86 (.12)
-.03 (2.20)
90%
.89 (.13)
-.010 (2.35)
Disgust
55%
.77 (.16)
.71 (2.01)
90%
.87 (.14)
.03 (1.86)
Fear
55%
.60 (.24)
.46 (1.96)
90%
.54 (.21)
-.28 (2.38)
Happy
55%
.83 (.20)
-.74 (2.33)
90%
.96 (.10)
-.71 (2.71)
Sad
55%
.76 (.17)
.66 (2.55)
90%
.89 (.12)
.26 (2.34)
Surprise
55%
.83 (.14)
.69 (2.33)
90%
.88 (.12)
-.48 (2.19)
Neutral
100%
.75 (.26)
-.65 (3.07)
Accuracy: Effects of Emotion and Intensity
An ANCOVA on accuracy revealed significant main effects of Emotion (F(5, 340) = 63.263,
p < .001, pη2 = .482), and Intensity (F(1, 68) = 70.727, p < .001, pη2 = .510), that were qualified by a
significant two-way interaction (F(5, 340) = 20.753, p < .001, pη2 = .234). Disgust (F(1, 68) = 57.232,
p < .001, pη2 = .457), happy (F(1, 68) = 46.491, p < .001, pη2 = .406), sad (F(1, 68) = 52.460, p <
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
15
.001, pη2 = .435), and surprise (F(1, 71) = 9.682, p = .003, pη2 = .125) were all recognized better at
high intensity, but fear was recognized better at low intensity (F(1, 68) = 11.722, p = .001, pη2 =
.147). Expressions showing anger were recognized equally well at low and high intensity (F(1, 68) =
2.866, p = .095, pη2 = .040). Bonferroni adjusted comparisons for the main effect of Emotion showed
that fear was recognized with least accuracy compared with all other expressions (all p < .001), and
happy was better recognized than disgust (p = .008), and sad (p = .006).
Accuracy: Effects of Boldness, Meanness, and Disinhibition
The main effects of Boldness (F(1, 68) = 0.270, p = .605, pη2 = .004), Meanness (F(1, 68) =
0.052, p = .820, 2 = .001), and Disinhibition (F(1, 68) = 1.624, p = .207, pη2 = .023) were all non-
significant, but there was a significant interaction of Meanness with Emotion (F(5, 340) = 3.589, p =
.004, pη2 = .050), suggesting a relationship that was dependent on the emotional content of the
expression. All other two- and three-way interactions of Boldness, Meanness, and Disinhibition with
Emotion and Intensity were non-significant (all F < 3.12, p > .08). When including total number of
previous convictions for violence as a covariate, the interaction of Meanness with Emotion remained
significant (F(5, 335) = 3.542, p = .004, pη2 = .050), and there were no significant main effects or
interactions of previous convictions for violence (all F < 1.70, p > .19). The interaction of Meanness
with Emotion also remained significant after removing 14 participants aged over 50 years (F(5, 270)
= 3.229, p = .008, pη2 = .056).
Table 3 shows the zero-order and partial correlations of Meanness, controlling for Boldness
and Disinhibition, with accuracy of emotion recognition. Zero-order and partial correlations showed
that increasing Meanness scores were associated with poorer fear recognition. Figure 1 shows the
association of Meanness scores, controlling for Boldness and Disinhibition, with accuracy of fearful
expression recognition. Partial correlations also showed that increasing Meanness scores were
associated with better recognition of sad expressions.
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
16
Table 3.
Zero-order and partial (controlling for Boldness and Disinhibition) correlations of TriPM Meanness
scores with accuracy of emotion recognition by type of expression
Note: Bold. = Triarchic Psychopathy Measure Boldness subscale; Disin. = Triarchic Psychopathy
Measure Disinhibition subscale
Pupil Dilation Response: Effects of Emotion and Intensity
An ANCOVA on pupil dilation responses showed that pupil reactivity varied with the
emotional content of the expression (F(5, 340) = 5.167, p < .001, pη2 = .071). Bonferroni adjusted
comparisons showed that the pupil dilated more for disgust (p = .004), and sad (p = .002), compared
with happy. No other comparisons were significant. A significant main effect of Intensity showed that
pupil dilation was greatest for expressions at lower intensity (F(1, 68) = 9.965, p = .002, pη2 = .128),
but the two-way interaction of Emotion and Intensity was non-significant (F(5, 340) = 1.321, p =
.255, pη2 = .019).
Pupil Dilation Response: Effects of Boldness, Meanness, and Disinhibition
A significant two-way interaction showed that the pattern observed for Intensity was most
pronounced with increasing Boldness scores (F(1, 68) = 4.023, p = .049, pη2 = .056). The remaining
two- and three-way interactions of Boldness, Meanness and Disinhibition with Emotion and Intensity
were all non-significant (all F < 1.48, p > .19). However, a significant main effect of Meanness (F(1,
68) = 4.138, p = .046, pη2 = .057) showed that increasing Meanness scores were associated with a
Emotion
Zero-order r (p)
Partial r (p)
(Controlling for
Bold. and Disin.)
Anger
.043 (.719)
.080 (.508)
Disgust
.023 (.845)
.142 (.240)
Fear
-.256 (.030)
-.241 (.044)
Happy
-.003 (.979)
-.036 (.767)
Sad
.066 (.580)
.241 (.044)
Surprise
.012 (.918)
.082 (.501)
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
17
reduction in the pupil dilation response across Emotion and Intensity. The main effects of Boldness
(F(1, 68) = 0.023, p = .881, pη2 = .000), and Disinhibition (F(1, 68) = 0.001, p = .970, pη2 = .000),
were both non-significant. When including total number of previous convictions for violence as a
covariate, the main effect of Meanness remained significant (F(1, 67) = 4.144, p = .046, pη2 = .058),
and we also found a significant interaction of previous convictions for violence with Emotion (F(5,
335) = 2.506, p = .030, pη2 = .036). The main effect of Meanness also remained significant after
removing 14 participants aged over 50 years (F(1, 54) = 4.127, p = .047, pη2 = .071).
Table 4 shows the zero-order and partial correlations of Meanness, controlling for Boldness
and Disinhibition, with pupil reactivity for each expression type. Zero-order correlations showed that
Meanness was associated with reduced pupil dilation responses across all emotional expressions
relative to neutral, excluding anger. When controlling for Boldness and Disinhibition, the effects of
Meanness were apparent for expressions of fear, happy, and sad. Figure 1 shows the association of
Meanness scores, controlling for Boldness and Disinhibition, with the pupillary response to fearful
expressions. Although an additional analysis revealed a significant interaction of previous convictions
for violence with Emotion, all zero-order and partial correlations with the pupil dilation response were
non-significant (all p > .204).
Table 4.
Zero-order and partial (controlling for Boldness and Disinhibition) correlations of TriPM Meanness
scores with pupil dilation response by type of expression
Emotion
Zero-order r (p)
Partial r (p)
(Controlling for
Bold. and Disin.)
Anger
-.216 (.068)
-.142 (.240)
Disgust
-.249 (.035)
-.180 (.137)
Fear
-.314 (.007)
-.298 (.012)
Happy
-.305 (.009)
-.239 (.047)
Sad
-.362 (.002)
-.306 (.010)
Surprise
-.248 (.036)
-.150 (.217)
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
18
Note: Bold. = Triarchic Psychopathy Measure Boldness subscale; Disin. = Triarchic Psychopathy
Measure Disinhibition subscale
Additional Analysis
To examine if the associations of fear face accuracy and pupil dilation responses with
Meanness were separate or overlapping, we included both in a regression model as predictors of
Meanness standardized residuals, controlling for Boldness and Disinhibition. The model (F(2, 71) =
5.369, p = .007, ΔR2 = .110) showed that reduced pupil dilation responses (β = -0.080, SE = .032, p =
.015), but not accuracy (β = -1.042, SE = .535, p = .055), predicted higher Meanness scores.
Figure 1. Scatter plot showing the relationship between Meanness psychopathic traits and (A) fear
recognition accuracy, and (B) the pupillary response to fearful expressions, in violent offenders.
Meanness scores represent standardized residuals controlling for Boldness and Disinhibition.
Discussion
In this study, we examined the effects of distinct psychopathic traits on accuracy of emotion
recognition, and pupil reactivity to different emotional expressions in a sample of convicted violent
offenders. In support of our main hypotheses, we found that self-reported levels of callousness as
indexed by the Meanness scale of the TriPM were associated with reduced recognition of fearful
expressions, and reduced pupil reactivity to emotional expressions of fear, happy, and sad. These
findings suggest that although callousness is associated with a specific impairment in fearful
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
19
expression recognition, the relationship of callousness with autonomic hypoactivity is pervasive
across emotional expressions, with no specificity for fear or sadness.
Consistent with earlier findings from offenders and non-offenders, expressions of higher
intensity were typically recognized with better accuracy (Gillespie et al., 2017; Schurgin et al., 2014;
Wells et al., 2016), and fear was recognized with least accuracy compared with other expressions
(Gillespie et al., 2017; Wells et al., 2016). The finding that callousness was associated with a specific
impairment in recognizing fearful expressions is consistent with earlier studies in community adults
(Brislin et al., 2018), and convicted offenders (Gillespie, Mitchell, et al., 2015; Igoumenou et al.,
2017). Our results contrast with reports of more pervasive psychopathy related impairments in
emotion recognition that go beyond fear and sadness (Brook et al., 2013; Dawel et al., 2012), and
instead favour theoretical accounts of psychopathy that focus on impaired recognition of others
distress cues (Blair, 2013; Blair et al., 2014). However, support for these theories is tempered by an
unexpected, positive relationship of callousness, controlling for Boldness and Disinhibition, with
accuracy for sad expressions. Although others have reported positive relationships of both
interpersonal and antisocial features of psychopathy with accuracy in offender samples (Dargis et al.,
2018; Igoumenou et al., 2017), a meta-analysis showed a small, negative effect of psychopathy on
recognition of sadness (Dawel et al., 2015). These findings should be interpreted in light of mixed
reports on the emotion specific effects of psychopathy that may reflect limited discriminating power
for emotion-specific subscales (e.g., happiness is usually recognized with high accuracy), small
sample sizes, and a lack of control over confounding third variables (Olderbak, Mokros, Nitschke,
Habermeyer, & Wilhelm, 2018).
Pupil reactivity varied in response to different emotional expressions, with greater responses
for disgust and sad compared with happy. These findings are consistent with earlier studies showing
that pupil dilation responses varied with the emotional content of a stimulus (Bradley et al., 2008;
Burley et al., 2017; Snowden et al., 2016). Furthermore, we found that pupillary responses were
increased for lower intensity expressions, likely a reflection of increased task difficulty and enhanced
cognitive effort (Sara, 2009). This effect was exaggerated with increasing Boldness scores, indicating
that the effects of Boldness on pupillary responses are dependent on stimulus intensity. In an earlier
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
20
study, we reported that Boldness traits were related to differences in the processing of emotional
facial expressions (Gillespie et al., 2017), and a recent study has highlighted an association of CU
traits with fear intensity-modulated amygdala responses (Meffert et al., 2018). Future research should
clarify the association of distinct psychopathic traits with pupillary responses that are modulated by
the emotional intensity of the stimulus. Contrast differences between the moderate and high intensity
expressions may also have affected responses in these conditions.
Crucially, we also found that violent offenders’ pupil dilation responses were associated with
levels of Meanness, and that this effect was pervasive across different expressions. Our results are the
first to show a relationship between pupil reactivity and callous psychopathic traits, and are consistent
with previously reported differences in autonomic reactivity in relation to callousness (Fanti, 2018;
Kyranides et al., 2017). Although Meanness was related to lower accuracy for fearful expressions
only, reductions in the pupil dilation response were observed more generally, for expressions of fear,
happy, and sad. Our findings for pupil reactivity are consistent with more pervasive emotional and
autonomic impairments in psychopathy, while results for accuracy favour an integrated emotions
perspective (Blair, 2013). Our findings mirror those of a systematic review by Brook et al. (2013),
which showed that findings from face-morph paradigms tend to favour an integrated emotions
perspective, while studies that found reduced autonomic reactivity tend to favour a more general
deficit in emotion processing. An additional analysis predicting Meanness from accuracy and pupil
reactivity to fear face affect showed that when entered simultaneously in to the model, only pupil
reactivity was a significant predictor of Meanness, suggesting that these effects may be overlapping.
This pattern of results suggests that fear recognition may rely more heavily on autonomic responses
driven by sub-cortical structures, while recognition of other emotions can be achieved by different
mechanisms.
To better place our findings in an overall framework of brain processes in psychopathy, it is
important to consider the neural circuits underlying changes in pupil diameter. Although the pupillary
response is thought to reflect activity in the LC (Joshi et al., 2016; Murphy et al., 2014), no known
anatomical pathways allow for a direct influence of LC on the size of the pupil (Nieuwenhuis et al.,
2011). Instead, it is thought that the LC and the SNS are activated in parallel, with the rostral
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
21
ventrolateral medulla representing a source of common input. While activation of the LC leads to
noradrenergic release into the neocortex (Corbetta et al., 2008; Coull et al., 1999; Sara, 2009),
activation of the SNS causes direct activation of the pupil dilator muscle. Further, recent evidence
suggests that noradrenaline improves sensory responses, and correlates with orienting toward
behaviorally relevant stimuli (Gelbard-Sagiv, Magidov, Sharon, Hendler, & Nir, 2018). Thus, the
pupil dilation response represents a novel avenue of enquiry for understanding attention-emotion
interactions in psychopathy. Our results suggest that impaired functioning of the LC-noradrenaline
circuit may represent a mechanism for the callousness features of psychopathy.
Strengths, Limitations, and Future Directions
Our results are subject to some limitations. First, the present study was limited to the
perception of emotion from faces, and future work should employ emotional vocalizations and bodily
poses, and unconditioned fear stimuli (e.g., snakes). Further, the facial expression stimuli were static,
and although morphing procedures were used to create expressions of varying intensity, it would be
interesting to examine these effects for more dynamic facial stimuli. Second, our sample was of a
modest size and largely limited to white Caucasian participants. Future studies should seek to
replicate our effects cross-culturally, as well as with female and developmental samples, and to
examine the role of potential moderating factors, including general mental ability (Olderbak et al.,
2018). Third, although the TriPM includes a Disinhibition subscale, this does not provide a direct
measure of antisocial behavior, and the scoring of this inventory does not take in to account official
records. Nonetheless, it is promising that we found a positive correlation of scores on the Meanness
and Disinhibition subscales with total number of previous convictions for violence, and the
relationship of Meanness with fear accuracy and pupil reactivity remained unchanged after controlling
for previous convictions for violence. Strengths of this study included the dimensional approach to the
assessment of psychopathy, and the measurement of negative emotionality (State and Trait anxiety).
Analyses presented in Supplemental Materials 2 showed that State anxiety was negatively related to
accuracy for fear. There were, however, no associations of either State or Trait anxiety with pupil
reactivity. Earlier findings have shown that levels of anxiety can be used to specify discrete variants
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
22
of psychopathy (Hicks & Patrick, 2006; Kimonis et al., 2012), and so it is important that future studies
examine how the pupillary response varies in these variants.
Conclusions
We found that the trait dimension of callousness was associated with impaired fear
recognition, and reduced pupil reactivity to varied emotional expressions in a sample of convicted
violent offenders. Conversely, although Boldness was associated with pupil reactivity as a function of
emotion intensity, we found little evidence that either Boldness or Disinhibition are related to face
affect processing or autonomic responses. Our findings support the use of pupillometry as a measure
of autonomic functioning for use with clinical and forensic samples. With a growing evidence base
detailing the neural circuits underlying the pupil dilation response, pupillometry can help to inform
understanding of attention-emotion interactions in psychopathy and other psychopathologies and
may be revealing about the role of the LC-noradrenaline circuit.
Running Head: PSYCHOPATHIC TRAITS AND PUPIL REACTIVITY
23
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... Additionally, antisocial tendencies have been found to exhibit a negative association with EI (Grieve and Panebianco, 2013). It is well-established that low EI is connected to antisocial and criminal behaviors (Gillespie et al., 2019), high rates of criminal recidivism (Fix and Fix, 2015), significantly impacting interpersonal functioning (Gillespie et al., 2019), empathy capacity, and the effective management of stress and mood levels (Fix and Fix, 2015). Despite this, further research is needed to thoroughly document this reduction in EI, given that the majority of studies have predominantly focused on men (Ermer et al., 2012). ...
... Additionally, antisocial tendencies have been found to exhibit a negative association with EI (Grieve and Panebianco, 2013). It is well-established that low EI is connected to antisocial and criminal behaviors (Gillespie et al., 2019), high rates of criminal recidivism (Fix and Fix, 2015), significantly impacting interpersonal functioning (Gillespie et al., 2019), empathy capacity, and the effective management of stress and mood levels (Fix and Fix, 2015). Despite this, further research is needed to thoroughly document this reduction in EI, given that the majority of studies have predominantly focused on men (Ermer et al., 2012). ...
... This modulation of the pupil size may serve as a valuable tool for assessing emotional processing in psychopathy. However, research is this area is limited, with studies demonstrating reduced pupillary affective modulation in psychiatric patients (Burley et al., 2019) and in prisoners with elevated psychopathy scores (Gillespie et al., 2019). Notably, this review revealed that female psychopaths in the community exhibited greater pupil size modulation when exposed to unpleasant sound clips (Burley et al., 2017). ...
... Studies of the affective modulation of the pupil in psychopathic individuals are limited. Burley et al. (2019) tested a sample of forensic psychiatric patients and found reduced affective modulation of the pupil for a range of negatively valenced stimuli (images and angry faces) and that the reduced affective modulation of the pupil was associated with Factor 1 of the PCL-R, but not Factor 2. Similarly, Gillespie et al. (2019) found that the pupil dilation caused by emotional faces was reduced in those with high scores on the Meanness scale of the TriPM in a forensic sample, with the deficit being found for all the types of emotional expression that were tested. However, Burley et al. (2017) failed to find any effect of psychopathy on the pupil's reaction to a range of emotional stimuli (images, sounds, and faces) in a community sample. ...
... Second, gender may also by important. The samples of Burley et al. (2019) and Gillespie et al. (2019) were all male, while that of Burley et al. (2017) was of mixed gender. Gender differences in behavioral correlates of psychopathy have been reported on several occasions (e.g., Vitale & Newman, 2001). ...
... These models differ in their conceptualization of psychopathy and there is no simple one-to-one correspondence between their scales. Fourth, the different studies have used a variety of stimuli to elicit the affective modulation of the pupil, including affective images (Burley et al., 2017(Burley et al., , 2019(Burley et al., , 2020, affective sounds (Burley et al., 2017), and emotional expressions on faces (Burley et al., 2017;Gillespie et al., 2019). It is currently unclear how these different stimuli-types may lead to differences in affective modulation of the startle response in relation to psychopathy. ...
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... Finally, trait meanness is posited to reflect the low pole of a neurobehavioral dimension of affiliative capacity (Palumbo et al., 2020), potentially involving widespread cortical and subcortical brain networks related to emotional empathy and pain processing (see Blair et al., 2018;Decety, 2011, for reviews). In this line, meanness-related traits predict deficits in emotional face recognition (Brislin & Patrick, 2019;Brislin et al., 2018;Gillespie et al., 2019;Mowle et al., 2019), increased pain tolerance (Brislin et al., 2016(Brislin et al., , 2022Miller et al., 2014), and lower ratings of perceived pain and elaborative processing of painful scenarios (Brislin et al., 2022) and aggressive situations (van Dongen et al., 2018). ...
... For example, Brislin and Patrick (2019) reported impairments in fear face recognition only in relation to trait meanness scores, while also finding blunted LPP responses for fearful and sad facial expressions. Similarly, Gillespie et al. (2019) reported, in a sample of incarcerated male offenders, 4 The low reliability of LPP affective modulation scores is another important factor that might have limited our ability to detect effects in the alternative-focus task. While low reliability of difference (or residualized) scores is a concern that can limit their validity as individual differences measures, these scores may still be useful for individual differences research, to the extent that a sufficient portion of their reliable variance relates to relevant criterion measures (see Patrick et al., 2019;Perkins at el., 2017 for a discussion on these issues and strategies for addressing it). ...
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One of the most prominent characteristics of psychopathy is a reduced processing of emotionally relevant information. However, it is still unclear how attentional mechanisms may modulate this deficit. The current study aimed to examine the impact of attentional focus on emotion processing in relation to the triarchic constructs of boldness, meanness, and disinhibition. Participants performed two tasks in which pleasant, neutral, and unpleasant framed pictures were presented. In the first task, participants were required to indicate the color of the frame (alternative-focus task), whereas in the second task they were instructed to indicate the emotional category of the image (affect-focus task). The Late Positive Potential (LPP) was used as an index of sustained engagement of attention to affective material. Confirming a successful task manipulation, we observed reduced LPP amplitudes, particularly for affective relevant material, in the alternative-focus task compared to the affect-focus task. Most interestingly, our results evidenced that trait meanness scores were associated with blunted elaborative processing of affective material (both appetitive and aversive) when this information was task-relevant (affect-focus task), but not when it was task-irrelevant (alternative-focus task). These findings indicate that high mean individuals are characterized by blunted elaborative processing of affective stimuli when their motivational relevance is determined in a top-down manner (i.e., when it is task-relevant). Our results highlight the need for further studying of the bottom-up and top-down dynamics of emotional attention in psychopathy.
... Participants were asked to self-report crimes they had been convicted of in their lifetime. Consistent with the literature, violent crimes were categorized as crimes in which the nature of the crime required violence against a victim (Gillespie et al., 2019;Trauffer & Widom, 2017). These crimes included carjacking, simple assault or battery, robbery, aggravated assault or battery, forcible rape, murder, homicide, or non-negligent manslaughter. ...
... There is now a considerable body of evidence that psychopathy is associated with profound disturbances in socio-affective functioning, including emotion regulation (Garofalo, Neumann, Kosson, et al., 2020;Garofalo & Neumann, 2018), recognizing emotional facial expressions (Dawel et al., 2012), understanding others thoughts, intentions and beliefs (Song et al., 2023), automatically taking the perspective of another (Drayton et al., 2018), and differences in neurophysiology in response to others' J o u r n a l P r e -p r o o f affective states (Gillespie et al., 2019;Jones et al., 2009;Lozier et al., 2014). It has been suggested that these problems in socio-affective functioning may, in part, help to explain why individuals with high levels of psychopathic traits show chronic and severe tendencies to harm others (Blair, 2013;Lozier et al., 2014). ...
... Studies investigating the relationship between psychopathy and autonomic arousal in response to prototypical facial emotion expressions have focused on pupil dilation and yielded mixed findings. Two studies found a negative relationship between interpersonal/affective psychopathic traits and pupil response [18,19], and two studies found no relationship between psychopathic traits and pupil response [20,21]. Youth with psychopathic traits have shown reduced SCR to prototypical fear faces but not prototypical anger faces [22]. ...
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Certain aspects of social deviance in psychopathy can be explained by deficits in recognizing facial expressions of emotion. Still, important questions remain unanswered regarding this relationship especially because literature still lacks: (a) a dimensional approach to psychopathy integrating the dominant models in the field; (b) multi-level data from behavioral ratings to physiological indicators; and (c) tasks providing high ecological validity by resorting into virtual reality (VR). This study aims to address these issues. The sample included 83 community-dwelling adult volunteers. Psychopathic dimensions of personality were measured with the Triarchic Measure of Psychopathy and Self-Report Psychopathy. Participants completed a VR task, which required them to identify avatars’ emotional facial expressions (happiness, sadness, fear, and neutral) under different eye-gaze conditions (eye contact 20% or 80% of the time). Behavioral ratings and eye-tracking data were collected. We hypothesized that fearlessness psychopathy traits would be related to increased deficits in fear recognition and less attention toward the eyes. No evidence was found however for emotion recognition deficits in psychopathy – although sadness was rated as a more positive-valenced emotion in individuals scoring higher in affective-psychopathic traits. Less attention toward the eyes was found uniquely in disinhibition traits. We discuss these results in light of their implications for how social information is processed and encoded in psychopathy.
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Impairments in processing fearful faces have been documented in both children and adults with psychopathic traits, suggesting a potential mechanism by which psychopathic individuals develop callous and manipulative interpersonal and affective traits. Recently, research has demonstrated that psychopathic traits are associated with reduced fixations to the eye regions of faces in samples of children and community-dwelling adults, however this relationship has not yet been established in an offender sample with high levels of psychopathy. In the current study, we employed eye-tracking with paradigms involving the identification and passive viewing of facial expressions of emotion, respectively, in a sample of adult male criminal offenders (n = 108) to elucidate the relationship between visual processing of fearful facial expressions and interpersonal and affective psychopathic traits. We found that the interpersonal-affective traits of psychopathy were significantly related to fewer fixations to the eyes of fear faces during the emotion recognition task. This association was driven particularly by the interpersonal psychopathic traits (e.g., egocentricity, deceitfulness), whereas fear recognition accuracy was inversely related to the affective psychopathic traits (e.g., callousness, lack of empathy). These findings highlight potential mechanisms for the subset of the interpersonal-affective traits exhibited by psychopathic individuals.
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Psychopathy consists of a constellation of affective-interpersonal features including lack of empathy, callousness, manipulativeness and interpersonal charm, impulsiveness and irresponsibility. Despite its theoretical and predictive value in forensic contexts, the relationships between the psychometric dimensions of psychopathy, including its antisocial features, and the construct’s neuropsychological characteristics remain uncertain. In this study, 685 personality-disordered prisoners with histories of serious violent or sexual offenses were assessed for psychopathy before completing a computerized and well-validated assessment of the ability to recognize emotional expressions in the face. Prisoners with more of the affective features of psychopathy, and prisoners with more of its antisocial manifestations, showed relatively poor recognition accuracy of fearfulness and disgust. These relationships were independent and modest but were still evident following correction for demographic features (e.g., ethnicity and socioeconomic status), mental illness (e.g., substance and alcohol misuse), personality disorders (other than antisocial personality disorder) and treatment status. By contrast, the associations between these dimensions of psychopathy and emotion recognition were diminished by controlling for cognitive ability. These findings demonstrate that variability in the ability of high-risk personality-disordered prisoners to recognize emotional expressions in the face—in particular, fear and disgust—reflects both the affective and antisocial aspects of psychopathy, and is moderated by cognitive ability.
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Research with developmental and adult samples has shown a relationship of psychopathic traits with reduced eye gaze. However, these relationships remained to be investigated among forensic samples. Here we examined the eye movements of male violent offenders during an emotion recognition task. Violent offenders performed similar to non-offending controls, and their eye movements varied with the emotion and intensity of the facial expression. In the violent offender group Boldness psychopathic traits, but not Meanness or Disinhibition, were associated with reduced dwell time and fixation counts, and slower first fixation latencies, on the eyes compared with the mouth. These results are the first to show a relationship of psychopathic traits with reduced attention to the eyes in a forensic sample, and suggest that Boldness is associated with difficulties in orienting attention toward emotionally salient aspects of the face.
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Psychopathic individuals show a range of affective processing deficits, typically associated with the interpersonal/affective component of psychopathy. However, previous research has been inconsistent as to whether psychopathy, within both offender and community populations, is associated with deficient autonomic responses to the simple presentation of affective stimuli. Changes in pupil diameter occur in response to emotionally arousing stimuli and can be used as an objective indicator of physiological reactivity to emotion. This study used pupillometry to explore whether psychopathic traits within a community sample were associated with hypo-responsivity to the affective content of stimuli. Pupil activity was recorded for 102 adult (52 female) community participants in response to affective (both negative and positive affect) and affectively neutral stimuli, that included images of scenes, static facial expressions, dynamic facial expressions and sound-clips. Psychopathic traits were measured using the Triarchic Psychopathy Measure. Pupil diameter was larger in response to negative stimuli, but comparable pupil size was demonstrated across pleasant and neutral stimuli. A linear relationship between subjective arousal and pupil diameter was found in response to sound-clips, but was not evident in response to scenes. Contrary to predictions, psychopathy was unrelated to emotional modulation of pupil diameter across all stimuli. The findings were the same when participant gender was considered. This suggests that psychopathy within a community sample is not associated with autonomic hypo-responsivity to affective stimuli, and this effect is discussed in relation to later defensive/appetitive mobilisation deficits.
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An identical sensory stimulus may or may not be incorporated into perceptual experience, depending on the behavioral and cognitive state of the organism. What determines whether a sensory stimulus will be perceived? While different behavioral and cognitive states may share a similar profile of electrophysiology, metabolism, and early sensory responses, neuromodulation is often different and therefore may constitute a key mechanism enabling perceptual awareness. Specifically, noradrenaline improves sensory responses, correlates with orienting toward behaviorally relevant stimuli, and is markedly reduced during sleep, while experience is largely "disconnected" from external events. Despite correlative evidence hinting at a relationship between noradrenaline and perception, causal evidence remains absent. Here, we pharmacologically down- and upregulated noradrenaline signaling in healthy volunteers using clonidine and reboxetine in double-blind placebo-controlled experiments, testing the effects on perceptual abilities and visually evoked electroencephalography (EEG) and fMRI responses. We found that detection sensitivity, discrimination accuracy, and subjective visibility change in accordance with noradrenaline (NE) levels, whereas decision bias (criterion) is not affected. Similarly, noradrenaline increases the consistency of EEG visually evoked potentials, while lower noradrenaline levels delay response components around 200 ms. Furthermore, blood-oxygen-level-dependent (BOLD) fMRI activations in high-order visual cortex selectively vary along with noradrenaline signaling. Taken together, these results point to noradrenaline as a key factor causally linking visual awareness to external world events. VIDEO ABSTRACT.
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Background Previous work has shown that amygdala responsiveness to fearful expressions is inversely related to level of callous-unemotional (CU) traits (i.e. reduced guilt and empathy) in youth with conduct problems. However, some research has suggested that the relationship between pathophysiology and CU traits may be different in those youth with significant prior trauma exposure. Methods In experiment 1, 72 youth with varying levels of disruptive behavior and trauma exposure performed a gender discrimination task while viewing morphed fear expressions (0, 50, 100, 150 fear) and Blood Oxygenation Level Dependent responses were recorded. In experiment 2, 66 of these youth performed the Social Goals Task, which measures self-reports of the importance of specific social goals to the participant in provoking social situations. Results In experiment 1, a significant CU traits-by-trauma exposure interaction was observed within right amygdala; fear intensity-modulated amygdala responses negatively predicted CU traits for those youth with low levels of trauma but positively predicted CU traits for those with high levels of trauma. In experiment 2, a bootstrapped model revealed that the indirect effect of fear intensity amygdala response on social goal importance through CU traits is moderated by prior trauma exposure. Conclusions This study, while exploratory, indicates that the pathophysiology associated with CU traits differs in youth as a function of prior trauma exposure. These data suggest that prior trauma exposure should be considered when evaluating potential interventions for youth with high CU traits.
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A lthough the am ygdala is widely believed to have a role in the recognition of em otion, a central issue concerns whether it is involved in the recognition of all em otions or whether it is m ore im portant to som e em otions than to others. W e describe studies of two people, D R and SE, with im paired recognition of facial expressio ns in the context of bilateral amygdala dam age. W hen tested with photographs showing facial expressions of em otion from the Ekm an and Friesen (1976) series, both D R and SE showed de® cits in the recognition of fear. Problems in recognising fear were also found using photographic quality im ages interpolated (``morphed' ') between prototypes of the six em otions in the Ekman and Friesen (1976) series to create a hexagonal continuum (running from happiness to surprise to fear to sadness to disgust to anger to happiness). Control subjects identi® ed these m orphed im ages as belonging to distinct er@ m rc-a pu .cam .ac.uk), or to A nd y Yo ung at the sam e address (T el: 01223 355294 x 710; F ax: 01223 359062; E-m ail: andy.young@ m rc-a pu.ca m .ac.u k). This research w as suppo rted by ES RC grant R 000234003. W e are deep ly indebte d to D R and to S E for their tim e and patience in co operatin g in ou r investigation. W e are grateful to Profes sor P. Ekm an for giving us perm issio n to u se and reprod uce im ages derived from th e Ek m an and Friesen (1976) Pictu res of F acial A ffect series, and to th e Press Associatio n for p erm ission to use press ph otographs.