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Herbal Teas and their Health Benefits: A Scoping Review


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Herbal teas are used as therapeutic vehicles in many forms of traditional medicine and are a popular global beverage. The purpose of this scoping review was to examine the evidence relating to the clinical efficacy and safety of herbal teas, and to identify the main research themes and gaps in knowledge to inform further work. A scoping review methodology was followed that set out the research question and described the sourcing, selection and analysis of studies. Overall, a total of 145 research publications were retrieved from global bibliographic databases, and after applying exclusion criteria, 21 remained. These studies looked at herbal tea use in female health, diabetes, heart disease and weight loss, with plant species including lavender, chamomile, fenugreek, stinging nettle, spearmint, hibiscus, yerba maté, echinacea and combinations of herbs. Observational studies explored associations between herbal tea consumption and cancer risk, liver health, and the risks linked to the consumption of environmental contaminants in the plant material. Despite plant materials being the basis for drug discovery, and the popularity of herbal teas, the number of articles exploring clinical efficacy and safety is small. In this review we discuss how herbal teas may be beneficial in some areas of clinical and preventative health, and what further research is required to understand whether regular consumption can contribute to healthy living more generally.
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Herbal Teas and their Health Benefits: A Scoping Review
Fatima S. Poswal
&Grace Russell
&Marion Mackonochie
&Euan MacLennan
&Emmanuel C. Adukwu
Vivien Rolfe
#Springer Science+Business Media, LLC, part of Springer Nature 2019
Herbal teas are used as therapeutic vehicles in many forms of traditional medicine and are a popular global beverage. The purpose
of this scoping review was to examine the evidence relating to the clinical efficacy and safety of herbal teas, and to identify the
main research themes and gaps in knowledge to inform further work. A scoping review methodology was followed that set out
the research question and described the sourcing, selection and analysis of studies. Overall, a total of 145 research publications
were retrieved from global bibliographic databases, and after applying exclusion criteria, 21 remained. These studies looked at
herbal tea use in female health, diabetes, heart disease and weight loss, with plant species including lavender, chamomile,
fenugreek,stinging nettle, spearmint, hibiscus, yerba maté, echinacea and combinations of herbs. Observational studies explored
associations between herbal tea consumption and cancer risk, liver health, and the risks linked to the consumption of environ-
mental contaminants in the plant material. Despite plant materials being the basis for drug discovery, and the popularity ofherbal
teas, the number of articles exploring clinical efficacy and safety is small. In this review we discuss how herbal teas may be
beneficial in some areas of clinical and preventative health, and what further research is required to understand whether regular
consumption can contribute to healthy living more generally.
Keywords Infusions .Plant medicine .Phytochemicals .Plant biodiversity .Herbal tea
In recent years, global mortality arising from non-
communicable diseases has overtaken infectious diseases,
with ischemic heart disease the most prevalent, and dementia
and diabetes now placed within the top 10 causes [1]. As
global life expectancy increases, research suggests that diet
and lifestyle changes at any time in life can improve vascular,
metabolic and cognitive health, therefore reducing the burden
of non-communicable disease [2]. Further clinical evidence
indicates that individuals need to prioritise plant materials like
fruit, vegetables, grain, nuts and oils, alongside lowering the
intake of red and processed meat and sugary drinks to achieve
a healthy diet [3]. However, these ambitions are compounded
by factors including the increased consumption of processed
foods and the dwindling availability of plant species, along-
side major global, socioeconomic and political challenges that
reduce access to a nourishing diet for many [4].
One possible solution to address these major challenges is
perhaps the consumption of valuable plant materials from other
dietary sources. The Government of the Netherlands, in their
national dietary guidelines, recommend people drink three cups
of green or black tea per day based on a body of evidence linking
tea consumption to the reduced risk of stroke and high blood
pressure [5]. The habitual consumption of black and green tea
derived from the plant Camellia sinensis dates back several thou-
sand years, and the medical benefits of the main polyphenolic
catechins and teaflavin compounds are well defined [6,7].
Alongside the ever-popular green and black varieties, tea can
be made with water infusions of the roots, leaves, flowers and
other component parts of a hugely diverse range of plant species.
These herbal teascontain a wealth of compounds and could
play a significant role in delivering nutrients and chemicals to
compensate for low quality diets.
Herbal teas have long-since been used as therapeutic vehi-
cles in Chinese, Indian and other indigenous medical systems
*Vivien Rolfe
Department of Applied Sciences, University of the West of England,
Frenchay Campus, Bristol BS16 1QY, UK
Pukka Herbs, The Chocolate Factory, Bristol BS31 2GN, UK
Centre for Research in Biosciences, University of the West of
England, Frenchay Campus, Bristol BS16 1QY, UK
Plant Foods for Human Nutrition
[810]. Chamomile and peppermint are the basis of some of
the most popular herbal teas, with the anti-inflammatory and
anti-mutagenic responses to chamomile, and relaxation effects
of peppermint oil on the gastrointestinal tract being
characterised [11,12]. Due to the low costs associated with
in vitro research, there is a wealth of preclinical information
about phytoconstituents and their pharmacology. However,
there is a need for more human research into observable ben-
efits in the short and long-term from herbal tea consumption,
including the efficacy of manufacturing techniques like fer-
mentation of the tea that creates a unique flavour and may
increase the biological activity.
The World Health Organisation seeks to capitalize on the use
of traditional medicines including herbal medicines in its 2014
2023 strategy, with the aim of keeping populations healthy
through providing access to effective and affordable alternatives
to medicine, and to provide healthcare choices coherent with
peoples cultural practices [13]. As these strategies become more
integrated into global and national healthcare policies, so has
grown the need to examine the important issues of efficacy,
safety and quality assurance through establishing evidence-
based approaches [14]. For example, there are safety concerns
regarding the levels of fluoride following black, green and herbal
teas consumption highlighting the need for robust quality assur-
ance and standards [15]. Also an area of concern is growing
availability of adulterated herbs and spices with dyes and bulking
agents, with individuals motivated by the economic advantages
of participating in a billion dollar industry [16].
What do we know of the health benefits of herbal tea, and
to what extent has research explored their clinical effective-
ness and safety? The main aim was to carry out a scoping
review to follow a precise methodology to examine the ex-
tent, range and nature of research activity around a particular
topic[17]. The implications for further research are discussed
along with the dominant research themes and gaps therein.
This scoping review utilised a six-step process (setting the
research question; sourcing studies; selecting studies; record-
ing data; summarising results; consulting on the findings) [17,
18]. The search strategy was informed by the PRISMA check-
list for reporting systematic reviews [19], and further en-
hanced by the recommendations of Narahari et al. [20]; these
approaches include the utilisation of relevant regional data-
bases and broadening the range of study types to gain a com-
prehensive and inclusive view of available research.
Article Eligibility Criteria
Articles were selected on the efficacy and safety of hu-
man herbal tea consumption, and excluded animal and
in vitro studies. Articles were included regardless of par-
ticipant age or health status. As defined by the World
Health Organisation (WHO), health included complete
physical, mental and social well-being and not merely
the absence of disease or infirmity[21], so studies were
included if they were interventions for clinical disease or
as part of preventative measures, including both physical
and mental health.
Herbal tea was defined as an aqueous infusion in hot or
cold water for an unspecified amount of time to extract the
phytochemical constituents of the plant materials. Studies
where herbs were administered as supplements, injected, or
delivered in other ways were excluded. Herbs that were either
administered individually or part of a blend in the tea were
included. Hot and cold teas were included.
BasedonNaraharietals[20] recommendations to
include a broad catchment of articles, both experimental
and observational studies were included: controlled trials
(randomised, non-randomised), controlled before and af-
ter studies, and observation studies (cohort or case con-
trol) with a comparison across two or more population
groups. Studies were included if they had measurable
health or clinical outcomes or used qualitative techniques
or self-reporting through questionnaires or interviews.
Case studies and review articles were excluded. Studies
were not excluded on the basis of language or if a full
text article was not available.
Search Strategy
A number of global electronic databases were searched with
no date restrictions: PubMed, Science Direct, MEDLINE
via EBSCO, AYUSH Research Portal and DHARA
Online. The search terms included (Humans) and (herbal
infusionor herbal teaor tisane)aswellas(healthor
clinicalor heath benefitsor health risksor well-be-
ing). The search was limited to the title and abstract, and
more simple search strategies were applied to some data-
bases. Further articles were retrieved through hand
searching reference lists, using Google Scholar and consult-
ing with experts in this field of work. The search terms and
process were developed iteratively.
Study Selection
The full references of articles retrieved or added from grey
literature were downloaded from the individual databases or
added manually into Microsoft Excel. An initial screening of
article titles and abstracts for inclusion or exclusion was car-
ried out in the database and results entered into Excel. Articles
were screened a further time by reading the full-text. Two
reviewers screened articles for inclusion with discrepancies
resolved with a third reviewer.
Plant Foods Hum Nutr
Data Collection
The details ofthe inclusion and exclusions were recorded. For
included articles that passed the two rounds of screening the
following data was gathered: Full reference; URL; Study iden-
tifier (authors and year of publication); methodologies; abbre-
viations and terminology used; participant details; location
details; herbal intervention details (botanical/Ayurvedic/tradi-
tional name; doses; duration of study); outcome measures;
concluding remarks. The datawas extracted by two reviewers.
Results were discussed by consultation between all of the
authors. A separate consultation took place with experts in
the field of herbal science.
The methodological quality or risk of bias of the included
articles was not critiqued as appropriate for a scoping
review [18]. The synthesis of evidence included a fre-
quency analysis of key research themes and depiction of
included and excluded studies. The characteristics of in-
cluded studies were reported in tables and clustered into
research themes within the discussion.
Results and Discussion
A total of 21 human studies examining the health benefits
of herbal tea consumption were identified (Fig. 1).
Sixteen clinical studies of varying methodological design
and quality evaluated the health benefits of drinking tea,
from the immediate effects of drinking lavender or cham-
omile to the benefits of longer-term consumption. Most
studies identified were randomised controlled studies that
utilized a placebo and some degree of blinding. Five stud-
ies were large-scale cohort studies or case controls,
reporting on health outcomes in relation to the frequency
of herbal or non-herbal tea consumption (with consump-
tion usually defined as one or more cups per day).
Details of Included Studies
Sixteen clinical studies (Table 1) and five observational stud-
ies (Table 2) were examined. Of the clinical studies, three were
small-scale clinical studies and the remainder were
randomised controlled trials (Table 1). In two studies of ma-
ternal health, lavender and chamomile herbal tea improved
sleep quality and remedied feelings of low mood in new
mothers [30,31]. Two studies explored whether nettle and
fenugreek teas improved lactation [32,33]. In a further study,
fenugreek tea consumption did not boost the levels of antiox-
idants in milk, which had been hypothesised to account for its
beneficial effects [34]. In a final study of maternal health, the
aroma characteristics of a fennel-based herbal tea were tested,
and there was no transfer of odiferous compounds into the
milk, which was initially a concern [35].
In other areas of womens health, spearmint tea was
perceived to be effective as anti-androgen therapy by fe-
male participants with poly-cystic ovary syndrome
(PCOS) who reported improvements in their symptoms
of hirsutism, although there were no changes to the ob-
jective clinical scores [28]. In a second spearmint study,
anti-androgenic effects were observed in a PCOS patient
group but not those with idiopathic hirsutism, indicating a
possible selective mode of action [29].
In hypertensive patients, and diabetic patients with hyper-
tension, hibiscus tea was shown to reduce blood pressure [24,
25]. In a study exploring the effects of beverage temperature
on physiological responses, a cold yerba maté tea (a South
American drink) altered the sensitivity of the cardiac barore-
flex, fat oxidation and energy expenditure when tested, al-
though there was no change in blood pressure or cardiac out-
put between the hot or cold teas [36].
For herbal tea as an intervention for weight loss and diabe-
tes, in an uncontrolled study, weight reductions were observed
in a group of volunteers drinking a combination of Garcinia
cambogia, Commiphora mukul and Cyperus scariosus [22].
For type 2 diabetes, a tea made with Populus tremuloides was
not effective in reducing markers of the disease, although was
well tolerated during the 10-day trial [26]. In 32 patients drink-
ing chamomile tea for 8 weeks, there were reductions in gly-
cosylated haemoglobin (HbA1c) and other serum markers of
diabetes, and these were accompanied by increases in total
serum antioxidant capacity and oxidative activity [27]. In a
Fig. 1 PRISMA flow diagram of the article selection process
Plant Foods Hum Nutr
Table 1 Characteristics of clinical studies evaluating herbal tea and health outcomes
Design Population Intervention Outcomes Reference
Non-controlled clinical study,
pre- and post- test surveys
35 male and female volunteers, 46kg
A slimming tea with Garcinia cambogia,
Commiphora mukul and Cyperus scariosus.2cups
daily for 2 months.
Tea reduced group weight on average by 1.5-2 kg.
Volunteers reported improvements - less oedema and
less feeling of bloating. No side effects.
RCT, placebo controlled, double
blind, cross-over
51 male and female patients with type 2
Salacia reticulata tea (n= 51) versus placebo (n = 51)
in cross-over design; 3 months.
Tea reduced HbA1C; reduced dose of anti-diabetic
drug glibenclamide but not metformin. Safe and
RCT, placebo controlled, double
65 pre- and mildly hypertensive male
and female adults not yet on
3 cups of brewed hibiscus tea (n= 35) versus placebo
beverage (hibiscus flavoured) (n= 30) for 6 weeks.
Hibiscus tea lowered SP compared to placebo at
6 weeks, and reduced mean arterial blood pressure
(p< 0.06). DP was lower for both at 6 weeks.
RCT, double blind 60 male and female diabetic patients
with mild hypertension not yet on
2 cups of hibiscus tea (n= 30) versus black tea
(n= 30) daily for 1 month.
3 patients in hibiscus group and 4 in black tea group
withdrew from study. Hibiscus reduced SP versus
increases in black tea group. No change to DP.
Hibiscus reduced mean pulse pressure.
RCT, placebo controlled, single
40 male and female patients with type 2
Herbal tea (Populus tremuloides and Heracleum
lanatum,n= 20) versus placebo (Chinese green
tea, mint and fennel, n= 20). 2 cups daily for
10 days.
No differences to a responder challenge, or HbA1c
between groups. Reduction in blood glucose for high
HbA1c subgroup. No toxic effects or adverse events
RCT, placebo controlled,
single-blind study
64 patients with type 2 diabetes (male
and female)
Chamomile tea (n= 32) versus control (water,
n= 32); 3 x day after meals for 8 weeks.
Chamomile significantly reduced HbA1c, HOMA-IR,
serum insulin and serum blood glucose levels
(adjusted for baseline variables); total AOX,
superoxide dismutase, glutathione peroxidase, and
catalase activity significantly increased.
RCT, placebo controlled, 2 centres 42 female volunteers with hirsutism in
Spearmint tea (n= 21) 2 x per day versus placebo
(n=21) for30 days.
At 30 days, 1 patient from spearmint group withdrew
(due to taste of tea). Spearmint significantly changed
hormone levels (reduced testosterone, elevated FSH,
LH), self-reported improvements in hirsutism but
not clinically rated scores.
Clinical study, 1 centre 12 female hirsute patients (with PCOS)
versus 9 with ideopathic hirsutism
Spearmint tea 2 x day for 5 days. Spearmint decreased free testosterone and increased
LH, FSH and oestradiol in PCOS.
RCT, pre- and post-test surveys 80 Taiwanese postnatal women with
poor sleep quality
1 x lavender tea daily (spending time to appreciate
and smell the aroma) (n= 40) for 2 weeks plus post
atal care versus control postnatal care only (n= 40).
Lavender tea reduced fatigue, reduced depressive
feelings and improved infant bonding at 2 weeks but
not at 4 weeks.
RCT, pre- and post-test surveys 80 Taiwanese postnatal women with
poor sleep quality
1x chamomile tea daily plus postnatal care (n= 40)
versus controls with postnatal care only (n= 40).
Reduced sleep deficiency and feelings of depression at
time of drinking but not after.
RCT, placebo controlled 95 mothers with infants born before
37 weeks gestation and < 2 kg birth
Stinging nettle tea (n= 32) versus fruit tea (n= 21)
versus placebo (n= 32); all had postnatal care.
Herbal increased milk production but induced no
change in serum prolactin levels. No changes in
infant weight gain between groups. No adverse
effects. Volunteers withdrew - 4 in nettle group; 4 in
fruit group and 2 in placebo group.
RCT, placebo controlled, double
66 mothers in early postnatal period Fenugreek (n= 22) versus placebo (apple, n=22)
versus placebo (no tea, n= 22). All had same care.
Fenugreek increased mean breast milk volume;
increased weight gain and babies regained their birth
weight faster than placebo and controls.
RCT, placebo controlled 80 healthy mothers in early postnatal
3 cups fenugreek tea daily (n= 40) versus water
placebo (n= 40) for 10 days.
No change in AOX levels in human milk from
fenugreek. OSI of breast milk samples taken in the
Plant Foods Hum Nutr
Tab l e 1 (continued)
Design Population Intervention Outcomes Reference
1st day and 710 d increased for both groups during
Non-controlled clinical study 5 volunteer new mothers Fennel-anise-caraway tea versus control tea in block
design 1 day sampling.
No influence of fennel tea on milk odour profiles. [35]
RCT, cross-over design 23 healthy male and female subjects Yerba maté tea hot (55o, n= 23) versus cold (3d,
n= 23) ingested over a 5 min period.
At 90 mins cold tea decreased heart rate, baroreflex
sensitivity, fat oxidation and energy expenditure. No
change in cardiac output or BP.
RCT, placebo controlled, double
blind, post test survey
95 people with early cold or flu
symptoms (males plus
predominantly females)
5 cups of echinacea tea daily (starting with 1 per day
and increasing; n= 48) for 2 weeks versus placebo
herbal tea (n= 47).
Echinacea relieved cold and flu symptoms and
shortened duration after 2 weeks via self-scoring
AOX, total antioxidant status or capacity, or oxidative stress index; BP, blood pressure; DS, diastolic pressure; FSH, follicle stimulating hormone; HbA1c, glycated haemoglobin; HOMA, homeostatic
model assessment for insulin resistance quantification; LH, lutenising hormone; OSI, oxidative stress index; PCOS, poly-cystic ovary syndrome; RCT, randomised controlled trial; SP, systolic pressure
Table 2 Characteristics of characteristics and outcomes of observational studies on herbal tea
Design Population Investigation / exposure Outcomes Reference
Cohort study 222 male and female Chinese student
volunteers Questionnaires on attitudes toward herbal tea
consumption, reporting of somatization and
alexithymia. Explored association with herbal tea
Attitudes toward herbal tea consumption significantly
correlated with somatosensory amplification (somatic
presentations of distress).
Case-control study 113 Greek patients with thyroid cancer;
286 benign thyroid disease, 138 healthy
controls. Males and females
Lifestyle interviews and questionnaires. Explored
association between chamomile tea consumption
and thyroid disease risk.
Chamomile tea (26 times per week) consumption
associated with reduced risk of thyroid cancer (i.e.,
drinking for 30 years reduced risk of thyroid cancer and
disease by 80%).
MIREC Study, Canada 1954 1st trimester, singleton, pregnant
females with available biological data Clinical, biological and questionnaire data.
Measures included heavy metals at 1st and 3rd
trimester, maternal and cord blood. Associations
for herbal tea versus non-tea drinkers.
Levels of arsenic, cadmium, mercury, manganese were
within normal ranges for consumption of herbal and all
teas. Lead levels at 3rd trimester were within normal
ranges but higher for herbal tea than non-herbal tea
MIREC Study, Canada 1898 1st trimester, singleton, pregnant
females with available biological data Clinical, biological and questionnaire data. Tests for
OC and OP at 1st and 3rd trimester in maternal
urine. Associations between pesticides and
drinking herbal tea.
Levels of OC and OP within normal ranges for herbal and
non-herbal tea drinkers. No adverse birth outcomes in
either group.
Rotterdam population study,
prospective cohort
2424 male and females over 45 years of
age with diagnosed liver stiffness
(fibrosis or sterosis)
Clinical, biological and questionnaire data as part of
larger Rotterdam study. Associations between
liver stiffness and herbal tea consumption (plus
other beverages).
Lower liver stiffness in herbal tea group compared to
non-herbal, whereas black and green tea conferred no
benefit. This was independent of a number of lifestyle
MIREC, Maternal-Infant Research on Environmental Chemicals; OG, organochlorine; OP, organophosphate
Plant Foods Hum Nutr
clinical study of three month duration, a tea made from
Salacia reticulata, a flowering plant from Sri Lanka, reduced
HbA1c and reduced the levels of one anti-diabetic drug re-
quired by patients to treat their disorder, but had no effect on
the dose of a second drug [23].
Only one study considered tea for infectious disease,
reporting benefits from echinacea tea for cold and flu
symptoms [37].
The effects of herbal tea consumption on health has been
the subject of a number of observational studies that looked at
associations with risk during pregnancy, risk of chronic dis-
ease and also mental health (Table 2). In a Canadian study,
herbal tea consumption was not associated with raising levels
of heavy metals and pesticides, and although levels of lead in
maternal blood were slightly elevated in herbal tea drinkers
compared to non-drinkers, these were low and well within
acceptable national standards [40,41].
In Chinese students vulnerable to stress, there was an asso-
ciation with somatosensory amplification and herbal tea con-
sumption, with the students reported benefits to drinking tea if
they were particularly emotionally withdrawn in times of
stress [38]. In a Greek population study, people who regularly
drank chamomile tea had a lower associated risk of thyroid
cancer and thyroid diseases, and there was a positive relation-
ship between the duration of drinking tea and reduction in
disease risk [39]. In Netherlands cohort study, herbal tea con-
sumption was associated with a lower risk of liver stiffness
compared to green or black teas, a clinical measure of fibrosis
or fatty liver disease determined by ultrasound [42].
Details of Excluded Studies
Figure 2illustrates the characteristics of studies that were
excluded after analysis of the full text. This provides an
indicator of the range of publications in this field of re-
search. A number were excluded for being the incorrect
article type i.e., wereacasestudyorareviewofherbal
tea, articles that were clinical studies of herbs delivered in
capsule or injected forms, or research into the phytochem-
ical profiles or herbs and their biological activity deter-
mined by in vitro testing or animal research. Some of
these articles are highlighted in the discussion.
Given the popularity of herbal teas and the desire to capi-
talize on traditional medicines like herbal products to keep
populations healthy [13], this review sought to provide a cri-
tique on the available literature relating to the health benefits
of herbal tea. Evidence suggests that diverse plant material
forms a vital component of the diet and could help combat
the significant burden of non-communicable disease [2], and
the use of herbals is postulated to have evolved alongside
advances in farming and food production as the nutritional
characteristics of our native diets became depleted of plant
phytochemicals [43]. Despite the level of global interest in
herbal teas and the recognised growing importance of plant-
rich diets, this review identified only 21 clinical and observa-
tional studies that looked at herbal tea and human health.
Herbs are rich in phytochemicals that are important constit-
uent secondary metabolities required for plant growth, natural
defence and communication, and are similar in structure to
many human biochemical compounds. Phenols are the most
abundant and widely explored for their antioxidant properties
[44], and the chemical properties of other compounds like the
steroidal components of saponins and sugar attachments of
glycosides form the basis of their biological activity [45].
Plants contain an abundance of phytochemical compounds
and these vary with the growing conditions of the plant, and
the farming and processing methods that form the value
chainthrough to the manufacture of products [46].
Hot, liquid-based herbal infusions provides the ideal
medium for water-soluble phytochemicals such as phenols
and flavonoids to be released and be potentially more
effective than just consuming the dried leaves of some
herbs [47]. Hot water facilitates the releaseofvolatileoils
from the herbs that enter the blood stream via the nasal or
respiratory mucosa, as demonstrated for rosemary and the
appearance of 1,8-cineole in the blood after a brief expo-
sure [48]. Tea is commonly used and simple to prepare,
and in the identified studies, teas were used for a number
of reasons. One paper explored a herbal remedy for dia-
betes based on healing practices of endogenous popula-
tions in North America that used herbal infusions [26]. In
other studies, the wide availability of herbs such as cham-
omile or lavender, which are popular herbal teas, offered a
simple therapy choice for breastfeeding women, given as
a post-natal regimen where alternatives to synthetic phar-
macological treatments were more desirable [3033].
This review excluded many articles that analysed the phe-
nolic composition and antioxidant capacity of herbs [49,50],
or that had characterised the anti-cancer, anti-inflammatory
and anti-microbial effects of herbs in vitro [51].Despite this
wealth of literature describing anti-cancer and antioxidant ac-
tivity, there were no clinical studies looking at herbal teas in
these areas. Probably, the lower potency and complexity of
herbal preparations render them a less appropriate delivery
vehicle compared to phytochemical extracts of active ingredi-
ents given in a controlled dosage [52,53]. Further variability
can arise from the phytochemicals and volatile compounds
behaving differently within an aqueous infusion, as demon-
strated for chamomile, so producing an infusion of a standard
biological benefit would be a challenge [54]. However, think-
ing about the longer-term and preventative benefits of regular
consumption is an alternative paradigm; one study on the re-
lationship between herbal tea and cancer, showed that the
regular consumption of chamomile tea (Matricaria
chamomilla L.) over a number of years was associated with
a reduced risk of thyroid cancer amongst healthy populations
Plant Foods Hum Nutr
in Greece [39]. One theory is that chamomile phytochemicals
interact with hydrogen peroxide, a reactive oxygen species
involved in thyroid hormone biosynthesis and implicated in
thyroid cancer pathophysiology [12]. Over 120 chemical con-
stituents for chamomile have been identified, such as terpe-
noids, flavonoids, and essential oils, and further studies would
confirm any pharmacological use in relation to cancer [55]. In
a second cohort study that queried participants on their
herbal tea, black or green tea, or coffee consumption over
the previous month, the consumption of herbal tea and
also three or more cups of coffee was linked to lower liver
stiffness as measured by clinical tests, which the authors
contributed to the antioxidant-activity of the beverages
Another surprising finding was that considering traditional
herbal medicines are widely used for their antimicrobial po-
tential, and have been well researched in vitro [56,57], only
one clinical study had looked at herbal tea for the treatment of
infection. In this small-scale RCT Lindenmuth et al. [-
37]observed that echinacea tea taken for two weeks reduced
symptoms of cold and flu compared to a placebo [37].
Echinacea is used clinically for the prevention of common
cold symptoms [58] and is effective in reducing the risk of
recurrent upper respiratory tract infections in susceptible indi-
viduals [59]. It could be that echinacea delivered as a herbal
infusion may provide a more convenient remedy for the com-
mon cold and further clinical studies could compare its effica-
cy with extracts delivered in other formats.
Herbal teas were used for the benefit of female health.
Healthcare workers recommended chamomile and lavender
teas to new mothers, encouraging them to savour the taste
and aroma for a 2-week period. Both teas reduced sleep defi-
ciency and lifted feelings of depression [30,31]. The mecha-
nisms of these herbs are reasonably well delineated; the flavo-
noid and monoterpene compounds in chamomile, and linolool
in lavender oil are used clinically in aromatherapy for pain
relief and relaxation [60,61], and they are used in neurological
and psychological conditions through affecting the limbic sys-
tem, GABAergic and cholinergic neuronal transmission [62].
These teas offer a convenient and safer alternative to pharma-
ceuticals for new mothers.
In other areas of female health, the galactagogue effects
of nettle and fenugreek teas were explored in nursing
mothers. Both herbs enhanced maternal milk production,
with fenugreek showing additional positive improvements
in infant weight gain, although the actions of fenugreek
were not linked to enhanced prolactin production [33,
34]. Stinging nettles contain phytosterols and are benefi-
cial in benign prostatic hyperplasia, and its biological ac-
tivity involves sex hormone binding globulin (SHBG), a
key regulatory molecule for testosterone and oestrogens
[63]. As SHBG also plays a role in pregnancy, birth and
lactation, it is plausible that it may be part of the mecha-
nism underlying the galactagogue effects observed, al-
though further research would confirm this. Fenugreek also
contains a number of active compounds in its seeds and
Fig. 2 Frequency and categorisation of excluded articles includingthose other than efficacy or observational studies; articles with a non-herbalor non-tea
intervention; articles relating to biological actions, herb toxicity and manufacturing methods
Plant Foods Hum Nutr
leaves, and the leaves in particular are rich in phytosterols
[64]. Since it is a widely used lactation aid, both from
traditional use and via recommendations from healthcare
professionals, there is guidance to standardise its use in
order to provide an alternative to synthetic pharmaceutical
drugs [65].
The anti-androgenic effects of plant phytochemicals was
demonstrated in two further studies, with observations that
spearmint tea (Mentha spicata) reduced blood levels of free
testosterone in females [29];the tea also improved patient self-
scoring of symptoms of hirsutism, although an absence of
change to objective clinical scores suggests that a longer du-
ration trial might be required to confirm efficacy [28]. A large
number of medical conditions utilise anti-androgen therapy
from hirsutism to cancer, and given that plant materials pro-
vide a pharmaceutical alternative and the option of fewer ad-
verse events, more clinical studies are needed to further un-
derstand these findings, and in particular, the longer-term ef-
fects associated with regulating hormonal activity [66].
In the WHOs Traditional Medicine Strategy [13], the use
of herbal medicines is argued for the treatment of chronic
diseases, and to provide more culturally accepted and trusted
therapeutic choices. The present review found articles relating
to teas commonly used in Indian medicine to treat diabetes
and obesity. Tea made from Garcinia cambogia, Commiphora
mukul and Cyperus scariosus was consumed for two months,
and Salacia reticulata (Kothala himbutu) tea was consumed
for three months [22,23]. In the first study which was un-
controlled, there were weight reductions and self-reported im-
provements relating to weight; in the second study, Salacia
reticulata tea reduced markers of type II diabetes and also
lowered the dose required for one diabetic medication. Little
is known of the phytochemical profiles and possible mecha-
nisms of the herbs in the first study, whereas Salacia reticulata
is rich in polyphenols including mangiferin, kitalanol and
salacinol, and these are thought to contribute to the
hypoglycaemic effect [67]. A further study explored a formu-
lation indigenous to North America containing the plants
Populus tremuloides - trembling aspen, and Heracleum
lanatum - cow parsnip. There were no changes in postprandial
blood glucose in a diabetic patient group, but in a subgroup of
those with more severe diabetes, positive effects were seen
following tea consumption [26]. The mechanisms by which
herbs and their constituents may exert anti-diabetic effects
may relate to the antioxidant effects of the phenolic compo-
nents as shown for herbs such as green tea and peppermint,
and the synergistic effects of differing combinations suggest
the potential importance of the whole herb over extracts of
singular phytochemical components [68]. Further good qual-
ity research on larger groups of patients with more severe
diabetes and poorer glycaemic control is warranted. With
global diabetes increasing in prevalence and the complexity
of drug regimens and side effects of medication hampering
treatment, alternative approaches that offer better patient com-
pliance are important.
In clinical studies of herbal tea and cardiovascular disease,
studies of tea made from Hibiscus sabdariffa, which is a pop-
ular tea in the United States, resulted in an anti-hypertensive
response [24,25]. Hibiscus contains high levels of phenols
and anthocyanins, and a meta-analysis of 128 randomised
controlled trials identified a range of cardiometabolomic
events influenced by anthocyanins including reductions in
systolic and diastolic blood pressure [69]. The underlying
mechanisms are likely to be complex involving the protection
against reactive oxygen species and targeting phosopholipase
pathways to reduce pro-inflammatory prostaglandins and leu-
kotrienes; also relevant to vascular endothelial function is the
inhibition of NF-kB signalling which has been shown to be
anti-atherosclerotic [70].
Alongside evaluating the clinical benefits of herbal tea con-
sumption, the safety aspects were also considered. Only seven
of the clinical studies retrieved reported any adverse events,
with the remaining ones failing to disclose this important in-
formation. Overall, the consumption of tea was not accompa-
nied by serious adverse symptoms and were well tolerated
(Table 1). Other concerns are that tea drinking may contribute
to the exposure from environmental pollutants. In a cohort of
pregnant mothers, no association was found between herbal
tea consumption and levels of heavy metals during pregnancy
with the exception that lead was higher but well within normal
and acceptable ranges, and there were no changes in pesticide
residues in maternal urine [40,41]. Such risks will arise from
poor sourcing standards that fail to measure the quality of the
original plant material. Booker et al. [46] make strong recom-
mendations to the sector to ensure products that are a medic-
inal standard, not just ensuring good levels of phytochemicals
in the materials, but to assure quality and provide consumers
with the reassurance that they are not contaminated.
This scoping review highlights a number of clinical
scenarios where herbal teas may be beneficial, but there
are many gaps where herbs are used medicinally but have
not been explored in a tea format. Turmeric is well
recognised for its anti-inflammatory potential, and in a
meta-analysis of eight randomised controlled trials, tur-
meric extract was effective in the treatment of arthritis
as determined by pain scores and an arthritis diagnostic
index [71]. Herbs also contain cognition-enhancing prop-
erties, for example the effects of waterhyssop or Bacopa
monnieri (L.) were assessed in a meta-analysis of 9 clin-
ical studies of largely healthy volunteers, and showed im-
proved cognition and speed of attention [72]. In other
areas, given the popularity of berry teas, and considering
the rich levels of phenolic compounds and proven biolog-
ical effects of these fruits [73], the present research iden-
tified no human studies looking at fruit or berry teas and
health. In one final area, herbal tea blends that include
Plant Foods Hum Nutr
ginger have been shown to provide an enriched sensory
experience and increased beverage consumption, and this
may have important application in specific areas of
healthcare for example social enrichment and better nutri-
tional care for the elderly [74], and again there were no
studies retrieved in relation to this.
Another gap in the literature retrieved was in relation to
some evidence from traditional Chinese medicine that fer-
mentation of herbs may increase their activity and therefore,
lead to more health benefits. Camellia sinensis leaves are
fermented to produced black tea with different health and
taste properties to green tea and there is emerging evidence
that this process can enhance the biological activity of some
herbs. For example, Artemesia capillaris is from the
Asteraceae family and is traditionally used as a hepatopro-
tective herb. Solid-state fermentation of Artemesia
capillaris using Ganoderma lucidum mycelium enhanced
anti-inflammatory activity compared to unfermented herb,
possibly through the biotransformation of polyphenolic
compounds into novel materials [75]. Fermentation of
Astragalus membranicus root with Aspergillus spp. in-
creased phenolic contents and antioxidant activity, includ-
ing the generation of novel phenolic compounds [76].
The present research had some limitations. In order to
compile a comprehensive and broad scoping review, arti-
cles were not excluded based upon their methodological
quality. As a result a number of small-scale, uncontrolled
studies were included whose results should be interpreted
cautiously. Whilst every attempt was taken to develop a
search strategy that utilised a number of global databases,
extra time could have been taken to improve upon this
with more iterative steps. However, following consulta-
tion with a specialist in the field, only one additional
clinical paper was identified suggesting that the searches
were reasonably sensitive. A data file is openly available
to highlight the transparency of the research process [77].
In conclusion, is a cup of herbal tea good for you? A small
number of clinical and observational studies have explored a
wide range of herbal teas that have demonstrated potential
clinical benefits in areas of female and maternal health, and
chronic conditions including diabetes, high blood pressure
and weight loss. Observational studies suggest there may be
associations between herbal tea consumption and a reduced
risk of liver and thyroid disease, indicating further research is
warranted to understand both the clinical treatment and pre-
ventative health potential of herbal teas.
In these studies identified, herbal teas provide a cost-
effective and enjoyable therapeutic option, being an alter-
native to pharmacological treatments which might be de-
sirable for example during pregnancy, or offering a cul-
turally fitting healthcare choice.
There are many options for future research, from
optimising the brewing conditions and understanding
synergistic effects, through to much needed good quality hu-
man studies to explore a wider range of herbal teas and their
nutrient and phytochemical constituents. Could herbal teas
play a role in improving plant diversity in our diet, and offset-
ting some of the deficiencies and growing number of chronic
disorders associated with depleted diets? In all of these areas,
more high-quality clinical studies are needed to evaluate the
efficacy and safety of herbal teas. An area not to be
overlooked in future research is the development of quality
assurance processes to ensure the herbs are sourced and
manufactured to a high standard.
Acknowledgements This research was co-funded between the
University of the West of England Internship Scheme and Pukka Herbs.
Compliance with Ethical Standards
Conflict of Interest Pukka Herbs is a manufacturer of herbal teas and
supplements. The data relating to this research is shared openly for
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Plant Foods Hum Nutr
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Malaria continues to be a major global health problem and a leading cause of death worldwide. Momordica charantia is a medicinal plant traditionally used in many parts of the tropics. The plant extracts have been shown to exhibit anti-bacterial, anti-viral, anti-parasitic effects as well as anti-diabetes. The aim of this study is to evaluate a commercial extract of M. charantia fruit for anti-malarial properties using an in vivo model of malarial infection (Plasmodium berghei NK65). Intra-peritoneal administration different doses of extract into ICR mice infected with P. berghei for four consecutive days resulted in chemo-suppressive and dose dependent manner also prolonged median survival of infected mice. The result mentions that the commercial extract displayed anti-malarial activity in vivo against P. berghei NK65.
... Herbal teas can be termed as a combination of dried leaves, seeds, grasses, nuts, barks, fruits, flowers, etc that gives them their taste and provide the benefits of herbal mixtures and are most appropriately called tisanes [60] . These herbal teas are used as therapeutic vehicles prepared as infusions in either cold or hot water to extract its active principles and taken when necessary [61] . Vicidomini et al., [29] reported that the intake of teas was a common way to treat respiratory diseases such as cough and cold, and [62] reported that aromatic herbal teas could ward off viral infections, especially the SARS CoV-2 virus. ...
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Four-fifth of people rely on phyto medicines to meet their healthcare needs. This study was undertaken to investigate the use of phyto medicines in preventing COVID-19. A total of 453 respondents participated in the survey via a well-structured questionnaire. Participants were mostly in the age group of 15-29 (38%) and 30-44 years (32%). Most (52%) residing in North-Central Nigeria, with 54% married, 43% singles, 55% have tertiary education and 38% are postgraduates. Thirty-five percent of them used herbs to prevent COVID-19, including ginger (38%), garlic (13%), and lemon (14%). Most respondents (73%) combined different plant parts, taken in form of teas (54%), liquid mixtures (19%), spices (5%), steam inhalation (7%), syrups (3%), and unprocessed (7%), while 38% engaged in self-medication, and 87% endorsed the development of herbal medicines to prevent COVID-19. This gives an insight into the formulation development of phytomedicine-based therapy for future consideration in the fight against the virus.
... However, the current literature has very little information on their storage stability in the form of freshly prepared infusions. 3,4 • Although many healthy effects of Punica granutum L. (pomegranate) have been revealed, knowledge of the bioactive substances and their biological characteristics of pomegranate leaf infusion (PLI) remains scarce. The richest compounds were ellagitannins (ETs) followed by flavonoid glycosides and phenolic acids. ...
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In recent decades, an intensive search for natural and novel types of antioxidant polyphenolics has been carried out on numerous plant materials. However, the current literature has very little information on their storage stability in the form of freshly prepared infusions. This study aims to characterize the polyphenolic composition and the antioxidant capacity of pomegranate (Punica granatum L.) leaf infusions over one-day storage (analyzed at 0, 2, 4, 6, 8, and 24 h). In addition we also intend to evaluate the effects of pomegranate leaf infusion administration on physiological parameters of FVB/n male mice during four consecutively weeks (ORBEA institutional approval). Spectrophotometric evaluation demonstrated that the infusion presented no significant changes in the content of total phenols (131.40–133.47 mg gallic acid g−1) and ortho-diphenols (239.91–244.25 mg gallic acid g−1). The infusion also maintained high stability (over 98% and 82%, respectively) for flavonoids (53.30–55.84 mg rutin g−1) and condensed tannins (102.15–124.20 mg epicatechin g−1), with stable (> 90%) potent antioxidant capacity (1.5–2.2 mmol Trolox g−1) throughout 0–24 h storage. The main decrease was observed during 0–2 h storage of flavonoids, 8–24 h storage of tannins, and 0–4 h storage of antioxidant capacity. Chromatographic analysis further revealed that 7 decreased and 11 increased compounds were found within 0–24 h storage. The good stability of the total polyphenolics and antioxidant properties might be related to the complex conversion and activity compensation among these compounds. The oral administration of pomegranate leaf infusion did not induce changes in mice’ mean body weight, mean food consumption and well-being. The findings suggest that pomegranate leaf infusion could be of great interest in the valorization of high added-value by-products and in the application of green and functional alternatives in the food-pharma and nutraceutical industries.
... ey are also delicious and simple to drink, making them a popular choice. A single herbal component or a combination of herbal ingredients in a herbal tea might be used to achieve a particular goal, including relaxation, rejuvenation, or the alleviation of a certain ailment [51,52]. erefore, from the present investigation, we have decided to formulate a polyherbal tea bag containing Ichnocarpus frutescens, Ficus dalhousiae, Crateva magna, Alpinia galangal, and Swertia chirata extracts. ...
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For the treatment and maintenance of postprandial blood glucose increases (i.e., diabetes mellitus), alpha (α)-amylase is a well-known therapeutic target. In this paper, we report an initial exploration of the work, i.e., in vitro alpha-amylase activity of the hydroalcoholic polyherbal extract of the selected plants. After drying, the plant material is ground individually, and at least 100 gm of the crude powder is prepared from each plant. 100 gm of each plant was combined, and a total of 500 gm of the crude powder (Ichnocarpus frutescens (100 gm) + Ficus dalhousie (100 gm) + Crateva magna (100 gm) + Alpinia galangal (100 gm) + Swertia chirata (100 gm)) was prepared to carry out the extraction. is obtained extract was subjected to preliminary phytochemical screening and in vitro alpha-amylase activity. At 16 mg/mL, acarbose displayed 78.40 ± 0.36% inhibition, whereas the extract exhibited 72.96 ± 0.70% inhibition, which is signi cantly comparable. e IC 50 value of acarbose was 12.9 ± 1.12, whereas the extract exhibited 13.31 ± 1.12 mg/mL. e extract possesses numerous classes of chemicals such as alkaloids, glycosides, tannins, polyphenols, and terpenoids, which can contribute to the antidiabetic activity through alpha-amylase inhibition. is was an initial exploration of the work as a proof of concept for the development of polyherbal tea bag formulation for the treatment of diabetes. In the future, we are aiming to investigate the e ectiveness of polyherbal tea bags in the treatment of diabetes using more in vitro and in vivo models. From the present investigation, we have concluded that this extract can be used for the treatment of diabetes.
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Background: This experimental study determined the in vitro, in vivo, and toxicity effects of Cinnamomum zeylanicum methanolic extract (CZME) against Toxoplasma gondii infection. Methods: The in vitro activity of CZME T. gondii tachyzoites was studied by the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. Infected mice were treated with CZME for two weeks at doses of 20, 40, and 60 mg/kg/day. Then, the therapeutic effects of CZME were evaluated by assessing the mean number and mean size of T. gondii tissue cysts, oxidant-antioxidant enzymes, pro-inflammatory cytokines, and mRNA expression levels of bradyzoite surface antigen 1 (BAG1) by real-time PCR. Results: CZME significantly (p <0.001) increased the mortality rate of parasites in a dose- and time-dependent response. The mean number of intracellular tachyzoites was significantly reduced after CZME therapy. The treatment of infected mice with CZME resulted in a significant (p <0.001) downregulation of BAG1 and the level of lipid peroxidation (LPO) and nitric oxide (NO) as oxidative stress markers. However, a considerable rise (p <0.05) was found in the levels of antioxidant markers such as glutathione peroxidase (GPx), catalase enzyme (CAT), and superoxide dismutase enzyme activity (SOD). In a dose-dependent response, after treatment of infected mice with CZME, the level of pro-inflammatory cytokines of IFN-γ, IL-1β, and IL-12 was considerably elevated. CZME had no significant cytotoxicity on Vero cells, with a 50% cytotoxic concentration of 169.5 ± 5.66 μg/ml. Conclusion: The findings confirmed the promising therapeutic effects of CZME on chronic toxoplasmosis in mice. Nevertheless, further investigations must confirm these results, elucidate its precise mechanisms, and examine its effectiveness in human volunteers.
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This study aimed to evaluate the different fermentation and drying methods in valorising Artemisia argyi H.Lév. & Vanio as herbal tea by comparing its bioactive compounds, in vitro anti-inflammatory, antioxidant and sensory quality with commercial Camellia sinensis (L.) Kuntze tea. The total phenolic, anti-inflammatory, and antioxidant activities of C. sinensis were higher (p<0.05) than A. argyi. Microwave drying and freeze drying increased the total phenolic, tannin, flavonoid, and antioxidant activity in fermented A. argyi. However, fermentation process decreased (p<0.05) the anti-lipoxigenase activity in A. argyi. The browning index of leaf samples was significantly correlated (r = 0.888, p<0.001) with the fermentation index. Principle component analysis showed that 65% of the accumulated variances in total phenolic, anti-inflammatory, antioxidant and sensory data of A. argyi were attributed to the different fermentation processes (35%) and thermal drying methods (30%). Although the consumer acceptance scores for C. sinensis tea was higher than A. argyi tea, freeze drying and microwave drying were identified as the preferred post-harvest processing methods for fermented A. argyi tea with optimal anti-inflammatory and antioxidant effect.
Over recent years, consumer interest in natural products, such as botanicals has increased considerably. One of the factors affecting their quality is the presence of mycotoxins. This review focuses on exploring the mycotoxin occurrence in botanicals (raw material and ready-to-eat forms such as infusions or tablets) and the risk assessment due to their ingestion. Aflatoxins, Ochratoxin A, and Fumonisins are the most commonly studied mycotoxins and data in the literature report levels ranging from traces to 1000 μg/kg in raw materials. In general, the highest contents observed in raw materials decreased to unconcerning levels after the preparation of the infusions, reaching values that generally do not exceed 100 μg/L. Regarding botanical dietary supplements, the levels observed were lower than those reported for other matrices, although higher levels (of up to 1000 μg/kg) have been reported in some cases. Risk assessment studies in botanicals revealed a higher risk when they are consumed as tablets compared to infusions. Analytical methodologies implied in mycotoxin determination have also been contemplated. In this sense, liquid chromatography coupled to fluorescence detection has been the most frequently employed analytical technique, although in recent years tandem mass spectrometry has been widely used.
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In the current study, we assessed health risk posed to Iranian consumers through exposure to metals via oral consumption of coffee, tea, and herbal tea of various trademarks collected from Iran market. Level of As, Cd, Cr, Cu, Fe, Hg, Ni, and Pb in 243 samples was quantified by inductively coupled plasma-optical emission spectrometry (ICP-OES). The metal levels in coffee samples from different trademarks of a specific country had statistically similar levels of metals; however, metal levels differed significantly among brand names form different countries. Metal levels in tea samples differed significantly between domestic and imported products, while different trademarks of similar countries did not show significant variations in this respect. Metal level in herbal tea samples did not show significant variations among different trademarks. Nevertheless, it should be highlighted that mean concentrations of metals statistically differed among different herbal tea samples. Deterministic hazard quotients (HQs) were <1.0 for all non-carcinogenic metals and total hazard index (HI) values indicated no risk; however, probabilistic assessment calculated HI values >1. In both deterministic and probabilistic scenarios, carcinogenic metals As and Ni had an estimated incremental lifetime cancer risk (ILCR) of medium level while that of Pb indicated no cancer risk. Sensitivity analysis showed that the concentration of metals had the most significant effect on non-carcinogenic and carcinogenic risks.
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Matthias B Schulze and colleagues discuss current knowledge on the associations between dietary patterns and cancer, coronary heart disease, stroke, and type 2 diabetes, focusing on areas of uncertainty and future research directions © Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to.
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Background Breastfeeding women with hypogalactia are commonly recommended to use fenugreek as a galactogogue. This study aimed to achieve formal consensus among breastfeeding women and healthcare providers on which potential harms and benefits of using fenugreek need to be communicated and discussed during clinical consultations. Methods A two-iterative round Delphi technique was used in two separate panels of breastfeeding women (n = 65) and healthcare providers (n = 56) to achieve formal consensus on a list of 24 and 16 items related to potential harms and benefits of fenugreek. Results About 70% of the healthcare providers recommended quite often herbal remedies for breastfeeding women and about 68% of the women had been recommended to use herbal remedies many times by their healthcare providers. Consensus was achieved on 21 potential harms and 14 potential benefits of using fenugreek to enhance human milk supply that need to be discussed with breastfeeding women during consultations. Conclusion Probably, potential harms and benefits of recommending fenugreek as herbal galactogogue for breastfeeding women seeking recommendations to increase their human milk supply need to be discussed during clinical consultations. Further observational studies are needed to assess what is being discussed in daily consultations when herbal remedies are recommended.
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Aim: Tea is usually consumed at two temperatures (as hot tea or as iced tea). However, the importance of drink temperature on the cardiovascular system and on metabolism has not been thoroughly investigated. The purpose of this study was to compare the cardiovascular, metabolic and cutaneous responses to the ingestion of caffeinated herbal tea (Yerba Mate) at cold or hot temperature in healthy young subjects. We hypothesized that ingestion of cold tea induces a higher increase in energy expenditure than hot tea without eliciting any negative effects on the cardiovascular system. Methods: Cardiovascular, metabolic and cutaneous responses were analyzed in 23 healthy subjects (12 men and 11 women) sitting comfortably during a 30-min baseline and 90 min following the ingestion of 500 mL of an unsweetened Yerba Mate tea ingested over 5 min either at cold (~3°C) or hot (~55°C) temperature, according to a randomized cross-over design. Results: Averaged over the 90 min post-drink ingestion and compared to hot tea, cold tea induced (1) a decrease in heart rate (cold tea: −5 ± 1 beats.min⁻¹; hot tea: −1 ± 1 beats.min⁻¹, p < 0.05), double product, skin blood flow and hand temperature and (2) an increase in baroreflex sensitivity, fat oxidation and energy expenditure (cold tea: +8.3%; hot tea: +3.7%, p < 0.05). Averaged over the 90 min post-drink ingestion, we observed no differences of tea temperature on cardiac output work and mean blood pressure responses. Conclusion: Ingestion of an unsweetened caffeinated herbal tea at cold temperature induced a greater stimulation of thermogenesis and fat oxidation than hot tea while decreasing cardiac load as suggested by the decrease in the double product. Further experiments are needed to evaluate the clinical impact of unsweetened caffeinated herbal tea at a cold temperature for weight control.
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Understanding interindividual variability in response to dietary polyphenols remains essential to elucidate their effects on cardiometabolic disease development. A meta-analysis of 128 randomized clinical trials was conducted to investigate the effects of berries and red grapes/wine as sources of anthocyanins and of nuts and pomegranate as sources of ellagitannins on a range of cardiometabolic risk biomarkers. The potential influence of various demographic and lifestyle factors on the variability in the response to these products were explored. Both anthocyanin- and ellagitannin-containing products reduced total-cholesterol with nuts and berries yielding more significant effects than pomegranate and grapes. Blood pressure was significantly reduced by the two main sources of anthocyanins, berries and red grapes/wine, whereas waist circumference, LDL-cholesterol, triglycerides, and glucose were most significantly lowered by the ellagitannin-products, particularly nuts. Additionally, we found an indication of a small increase in HDL-cholesterol most significant with nuts and, in flow-mediated dilation by nuts and berries. Most of these effects were detected in obese/overweight people but we found limited or non-evidence in normoweight individuals or of the influence of sex or smoking status. The effects of other factors, i.e., habitual diet, health status or country where the study was conducted, were inconsistent and require further investigation.
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Background and objectives: Poor breast milk production is the most frequent cause of breastfeeding failure in preterm babies. The aim of our study is to evaluate the effect of herbal tea mixture containing stinging nettle (Natal, Hipp) on breast milk production and serum prolactin levels of mothers, and weight gain of preterm babies. Materials and methods: We enrolled mothers and their babies who were less than 37 gestational week and less than 2000 g, fed with orogastric tube without any contraindication of enteral feeding in neonatal intensive care unit between November 2010 and June 2011. The mothers of treatment group (n = 32) were consuming commercially available herbal mixture tea for 1 week. The mothers control group (n = 21) received only the same advice on supportive measures as group I. Mothers in the placebo group (n = 32) were given fruit tea for 1 week. The daily breast milk production of mothers and weight gain of preterm babies were recorded. Also, serum prolactin levels of the mothers were measured. Results: Increase of the milk production from the first to the seventh day was more prominent in mothers using herbal tea mixture. Increased rate in the amount of milk was 80% in the treatment, 34.3% in the placebo and 30% in the control group (P = 0.000). There was no statistically significant difference in weight gain of babies between the two groups, due to formula feeding in case of insufficient breast milk. Serum prolactin levels of the mothers at the beginning and on the seventh day showed no significant difference. Conclusions: In mothers with premature babies and who are treated in neonatal intensive care unit, consumption of galactogogue herbal tea will increase lactation and prevent lack of human milk without any adverse effect.
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Tea-ginger drink was selected for evaluation due to its nutraceutical potential. Panelists rated preference for drinks prepared from tea, ginger, and tea+ginger powder for colour, taste, and aroma. The obtained data were evaluated using analysis of variance, principal component analysis, and agglomerative hierarchical clustering. Also the colour preference scores were evaluated against instrumental colour measurements. The ginger drink had lower rating for colour preference and the tea drink had lower ratings for aroma and taste preference. However, the tea-ginger drink led to enhanced colour, aroma, and taste ratings. The colour preference was found to have highest correlation coefficient with the hue and chroma of the drinks [r(58)=−0.583, P<0.05 and r(58)=0.566, P<0.05]. This study suggests that a sensory quality deficiency in a particular plant based drink could be compensated for by blending the drink with another plant based drink. This approach could help improve the uptake of plant based nutraceutical drinks.
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Biodiversity is key for human and environmental health. Available dietary and ecological indicators are not designed to assess the intricate relationship between food biodiversity and diet quality. We applied biodiversity indicators to dietary intake data from and assessed associations with diet quality of women and young children. Data from 24-hour diet recalls (55% in the wet season) of n = 6,226 participants (34% women) in rural areas from seven low- and middle-income countries were analyzed. Mean adequacies of vitamin A, vitamin C, folate, calcium, iron, and zinc and diet diversity score (DDS) were used to assess diet quality. Associations of biodiversity indicators with nutrient adequacy were quantified using multilevel models, receiver operating characteristic curves, and test sensitivity and specificity. A total of 234 different species were consumed, of which <30% were consumed in more than one country. Nine species were consumed in all countries and provided, on average, 61% of total energy intake and a significant contribution of micronutrients in the wet season. Compared with Simpson's index of diversity and functional diversity, species richness (SR) showed stronger associations and better diagnostic properties with micronutrient adequacy. For every additional species consumed, dietary nutrient adequacy increased by 0.03 (P < 0.001). Diets with higher nutrient adequacy were mostly obtained when both SR and DDS were maximal. Adding SR to the minimum cutoff for minimum diet diversity improved the ability to detect diets with higher micronutrient adequacy in women but not in children. Dietary SR is recommended as the most appropriate measure of food biodiversity in diets.
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Traditional tea (Camellia sinensis) and herbal tea are being consumed across the world. However, long term consumption of tea can increase the chances of fluorosis owing to the presence of fluoride (F) in teas. Therefore, it is imperative to assess the health risk associated with tea consumption. The main objectives of this study were to: 1) estimate total F in 47 popular teas, including traditional and herbal teas and F concentrations in 1% (w/v) infusion of 5 min, and 2) assess the exposure risks of F from tea consumption in children and adults. The data showed that total F was the least in herbal teas (33 e102 mg/kg) and their infusions (0.06e0.69 mg/L) compared to traditional teas (296e1112 mg/kg) and their infusions (1.47e6.9 mg/L). During tea infusion, 6e96% and 18e99% of the F was released into the water from herbal and traditional teas, respectively. Ten samples of traditional teas, including five green teas had chronic daily intake (CDI) values of F > 0.05 mg/d/kg bw, the stipulated permissible limits of F intake from all sources. Although the F from teas posed no immediate health hazards with hazard quotient <1, some tea samples could potentially contribute >4 mg F/d, thereby adding to the overall F burden. Therefore, together with F from food and water sources, daily F consumptions from teas might increase its health risks to humans. So, caution should be excised when drinking teas containing high F. Published by Elsevier Ltd.
Background Although lifespan is increasing, there is no evidence to suggest that older people are experiencing better health in their later years than previous generations. Nutrition, at all stages of life, plays an important role in determining health and wellbeing. Methods A roundtable meeting of UK experts on nutrition and ageing considered key aspects of the diet–ageing relationship and developed a consensus position on the main priorities for research and public health actions that are required to help people live healthier lives as they age. Results The group consensus highlighted the requirement for a life course approach, recognising the multifactorial nature of the impact of ageing. Environmental and lifestyle influences at any life stage are modified by genetic factors and early development. The response to the environment at each stage of life can determine the impact of lifestyle later on. There are no key factors that act in isolation to determine patterns of ageing and it is a combination of environmental and social factors that drives healthy or unhealthy ageing. Too little is known about how contemporary dietary patterns and sedentary lifestyles will impact upon healthy ageing in future generations and this is a priority for future research. Conclusions There is good evidence to support change to lifestyle (i.e. diet, nutrition and physical) activity in relation to maintaining or improving body composition, cognitive health and emotional intelligence, immune function and vascular health. Lifestyle change at any stage of life may extend healthy lifespan, although the impact of early changes appears to be greatest.