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Statistical analysis and prospective application of the GM-scale, a semi-harmonic EMF scale proposed to discriminate between 'coherent' and 'decoherent' EM frequencies on life conditions

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The Generalized Music (GM)-scale is an acoustic (octave-like) algorithm of 12 tones that describes the electromagnetic (EM) frequency band pattern discovered from a meta-analysis of in total 468 biomedical research papers. These studies reported either beneficial or detrimental effects of electromagnetic frequencies (EMF) on biological tissues/cells in vitro or whole organisms in vivo. The apparent quantized pattern of EM frequency bands was postulated to represent a potential 'quantum algorithm of life'. In the present paper a statistical analysis is made of the overall data underlying this patterned EM frequency distribution. Data were sorted according to their features to be either beneficial, 'coherent' frequencies or detrimental, 'decoherent' frequencies and grouped around the theoretical 12 GM-scale values. A Wilcoxon rank sum test was used to discriminate between these data populations and this test showed that the difference between the 'coherent' and 'decoherent' data sets is indeed statistically significant (p<0.0025) for all of the 12 GM-scale groups. The mean values of the groups correspond very well with the postulated GM-scale values (difference <0,9%). To analyze the fit of the biomedical EM-frequency data to the GM-scale algorithm values, 24 alternating and "decoherent' frequency bands were defined and the life data were plotted in these bands. This test showed that 89.4% of 'coherent' data and 83.4% of 'decoherent' data corresponded to their respective frequency bands. The particular band widths, and consequently the related error margins, are very small (2.6%-3.3%). A prospective method is demonstrated to apply the GM-scale algorithm to identify (label) experimental or already published EM frequency data as potential "coherent' or "decoherent'. These and future analyses of experimental data with respect to the fit of their EM frequencies to the GM-scale will help to further validate this algorithm as a new biophysical principle.
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Quantum Biosystems | 2019 | Vol 10 | Issue 2 | Page 33 51 33
Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
www.quantumbiosystems.org
Statistical analysis and prospective
application of the GM-scale,
a semi-harmonic EMF scale proposed to
discriminate between coherent and
decoherent EM frequencies
on life conditions
Trudi Sonderkamp*, Hans (J H) Geesink** and Dirk K F Meijer***
Abstract
The Generalized Music (GM)-scale is an acoustic (octavelike) algorithm of 12 tones
that describes the electromagnetic (EM) frequency band pattern discovered from a
meta-analysis of in total 468 biomedical research papers. These studies reported
either beneficial or detrimental effects of electromagnetic frequencies (EMF) on
biological tissues/cells in vitro or whole organisms in vivo. The apparent quantized
pattern of EM frequency bands was postulated to represent a potential quantum
algorithm of life. In the present paper a statistical analysis is made of the overall
data underlying this patterned EM frequency distribution. Data were sorted
according to their features to be either beneficial, coherent frequencies or
detrimental, decoherent frequencies and grouped around the theoretical 12 GM-
scale values. A Wilcoxon rank sum test was used to discriminate between these d ata
populations and this test showed that the difference between the coherent and
decoherent data sets is indeed statistically significant (p<0.0025) for all of the 12
GM-scale groups. The mean values of the groups correspond very well with the
postulated GM-scale values (difference <0,9%). To analyze the fit of the biomedical
EM-frequency data to the GM-scale algorithm values, 24 alternating and
“decoherent’ frequency bands were defined and the life data were plotted in these
bands. This test showed that 89.4% of coherent data and 83.4% of decoherent
data corresponded to their respective frequency bands. The particular band widths,
and consequently the related error margins, are very small (2.6%-3.3%). A
prospective method is demonstrated to apply the GM-scale algorithm to identify
(label) experimental or already published EM frequency data as potential “coherent
or “decoherent’. These and future analyses of experimental data with respect to the
fit of their EM frequencies to the GM-scale will help to further validate this algorithm
as a new biophysical principle.
Key Words: Generalized Music-scale, GM-scale, electromagnetic radiation, EMF, statistics,
statistical analysis, EM frequency distribution patterns, coherence/decoherence balance,
electromagnetic frequencies
Quantum Biosystems 2019; 10 (2): 32-51
* Ir. Biochemist, Sonderkamp Research, Eindhoven, email:
t.sonderkamp@kpnmail.nl ** Previous: Ir, Project leader
mineral Nanotechnology, DSM-Research, the Netherlands ***
Em. Professor of Pharmacokinetics and Drug
Targeting,University of Groningen, the Netherlands
Address: Groningen, Parklaan 17, 9724 AN, The Netherlands
e-mail: meij6076@planet.nl
Introduction
Over the years evidence has been
accumulating that electromagnetic
radiation plays a role in intercellular and
intracellular communication and probably
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Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
www.quantumbiosystems.org
also in communication between
organisms. For a review see Fields of the
Cell, edited by D. Fels, M. Cifra and F.
Scholkmann (2015).
In search for an underlying
mechanism for such effects of
electromagnetic frequencies (EMF),
(Geesink and Meijer, 2015) found a
striking, band-like, distribution pattern of
frequencies of electromagnetic radiation
that either affect life systems in a life
sustaining way or a life-endangering
manner (Geesink & Meijer, 2016).
[1]
En : Energy distribution,
ωref : Reference frequency = 1 Hz,
: Reduced Planck’s constant,
n : Series of integers: 0, 0.5, 2, 4, 5, 7, 8, -1, -3, -4,-6,
-7,
m : series of integers: 0, 1, 2, 3, 4, 5, -1, -2, -3, -4, -5,
p : Series of integers: <-4, -4, -3, -2, -1, 0, 1, 2, 3, 4,
5, 6, > +52
A mathematical algorithm for the
beneficial (so-called coherent) frequencies
pattern was revealed and shown to be
analogous to a tempered Pythagorean
acoustic scale that therefore was called the
GM-scale. A literature survey of initially
175 independent biological studies showed
that 97 electromagnetic frequencies (EMF)
that were reported to exhibit beneficial
effects fitted on this logarithmic GM-scale,
whereas 5 frequencies with detrimental
effects did not (Geesink & Meijer, 2016).
In later work this survey was extended
to 468 biomedical papers including work
on cancer-related effects of
electromagnetic radiation and spanning a
range of Hz to PHz (Geesink & Meijer,
2018c) and the GM-scale pattern was
further defined and generalized.
After normalization to the same
octave (by dividing or multiplying by
powers of 2; (2p) in equation [1]),
experimental EMF with beneficial effects
generally fitted the theoretical GM-scale
very well, whereas frequencies with
detrimental effects generally fell in
between GM-scale coherent scale values,
see Figure 1 (Geesink & Meijer, 2018c).
Figure 1: Measured frequency data of living cells systems that are life-sustaining (coherent data: green points)
and detrimental for life (decoherent data: red squares) versus calculated normalized frequencies. Biological effects
measured following exposures or endogenous effects of living cells in vitro and in vivo at frequencies in the bands of
Hz, kHz, MHz, GHz, THz, PHz. Green triangles plotted on a logarithmic x-axis represent calculated life-sustaining
frequencies; red triangles represent calculated life-destabilizing frequencies. Each point indicated in the graph is taken
from published biological data and are a typical frequency for a biological experiment(s). For clarity, points are
randomly distributed along the Y-axis.
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Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
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The particular GM-scale interference
pattern has been postulated to be
interpreted as a quantized pilot wave
steering pattern, which could represent the
supposed potential wave frequencies of the
‘hidden variable’ quantum theory of Bohm
(1952), and thus be related to quantum
coherence and entanglement. (Geesink &
Meijer, 2018c, 2018a, 2018b).
The pattern was shown to have
similarity with the typical geometric forms
that are induced by sound on particle
covered vibrating plates in the
experiments of Chladni (Chladni, 1787;
Geesink & Meijer, 2016, 2017b), as later on
mathematically and numerically expressed
by Ritz (1909). The pattern turned out to
be valid for a variety of other inanimate
systems, including EMF promoting
entanglement in EPR-experiments
(Geesink & Meijer, 2018d) and in
superconductivity (Geesink & Meijer,
2019). It was therefore hypothesized as a
potential ‘quantum algorithm of life’ and
generalized as a novel biophysical
principle, having a predictive value in life
systems and beyond. (Geesink & Meijer,
2017b, 2017a, Meijer & Geesink, 2016,
2018).
In the present work the
discriminating power of the GM-scale is
tested through a statistical analysis of
the original experimental data, with
regard to their distribution and fit to
the GM-scale. The Wilcoxon rank sum
test was used to discriminate between
populations (Gibbons & Chakraborti,
2011; Hollander & Wolfe, 1999;
Wilcoxon, 1945). Based on the
observations in the current study
recommendations for prospective
application of the GM-scale are made.
Table 1. Generalized GM-scale of ‘coherent’ frequencies (See equation 1 above)
2. Methods
Data were obtained from reference
(Geesink & Meijer, 2018c), from which a
few incidental data were corrected to
arrive at the definite list of frequencies
(see Appendix 1) .
Calculations were performed using
Microsoft Excel 2016 and MATLAB
Statistics Toolbox R2017b, The
MathWorks, Inc., Natick, Massachusetts,
United States.
All data were transposed to frequency
data between 1 and 2 Hz, by dividing by
2m, according to the generalized GM-scale
of coherent frequencies, shown in Table
1.
From these formulae the 12 values of
the ‘coherent’ GM-scale between 1 and 2
Hz can be derived as well as 12 values of
the decoherent scale, that are positioned
in the middle between 2 coherent steps
on a logarithmical scale. This pattern is
shown in Table 2.
Tests were performed to answer
following questions:
1. What is the significance of the
difference between “coherent’ and
“decoherent’ data sets?
2. What is the congruency of
“coherent’ and “decoherent’ data
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Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
www.quantumbiosystems.org
with the GM-scale values, based on
frequency intervals?
3. What is the congruency of
“coherent’ and “decoherent’ data
with GM-scale values based on
population equality tests?
4. How to apply the GM-scale to
evaluate experimental data in a
prospective manner?
Table 2. ‘Coherent’ and ‘Decoherent’ frequency values of the GM-scale algorithm of 12 tones between 1 and 2
Hz. Coherent’ values are depicted in green (Hz) and ‘decoherent’ values in orange (Hz)
Ad 1.
Coherent data were grouped in intervals
around the steps of the coherent scale
with edges in the middle between 2 steps
on a logarithmic scale (edges=decoherent
values), resulting in 12 coherent
datasets, C1 to C12, see Table 2.
Decoherent data were grouped around
the steps of the decoherent scale with
edges in the middle between 2 steps on a
logarithmic scale (edges=coherent
values), resulting in 12 “decoherent’
datasets, D1 to D12, Table 2. Per dataset
mean, median, standard deviation and
probability distribution was calculated. A
Wilcoxon rank sum test between these
groups was performed in Matlab with
alpha=0.01. The Wilcoxon rank sum test
(Gibbons & Chakraborti, 2011; Hollander
& Wolfe, 1999; Wilcoxon, 1945) is a
nonparametric test for two populations
when samples are independent. This test
is equivalent to a Mann-Whitney U-test
(Mann & Whitney, 1947) and can be
applied to samples of different size. This
test was chosen because the analyzed
data are obtained from a literature survey
of articles that are not related to each
other and therefore independent.
Furthermore data populations are
relatively small (N≤31) and of unequal
size.
Ad 2.
Frequency intervals between coherent
and decoherent steps are positioned in
the middle between each step on a
logarithmic scale (edges in between
coherent and decoherent scale values,
Table 5), resulting in 24 alternating
coherent and decoherent intervals. The
percentage of points falling in the correct
intervals were subsequently calculated.
Ad 3.
Theoretical GM-scale populations, that
precisely fit GM-scale values, were
generated in Matlab, using the functions
‘makedist’ and ‘random’. The theoretical
populations exist of 12 x 100 points
normally distributed around each GM-
scale value (X1 to X12), with standard
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Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
www.quantumbiosystems.org
deviation (SD) based on GM-scale band
widths. Band widths calculated in test 1 are
taken as a measure for the SD of each
population. The SD is calculated assuming
each interval to be a 90% probability area
and consequently each interval=2 x 1.64 x
SD, SD=interval width/(2x1.64).
A Wilcoxon rank sum test with
alpha=0.05 between the coherent
datasets C1 to C12 and the GM-datasets X1
to X12 was performed using Matlab. In a
similar way random sets were produced
around the decoherent scale values with
SD as specified in Table 8. A Wilcoxon
rank sum test with alpha=0.05 between
the decoherent datasets D1 to D12 and the
GM-datasets (X’1 to X’12) was performed
using Matlab.
Ad 4.
Based on the results of tests 2 and 3
the method of test 2 is selected to
demonstrate the prospective application of
the GM-scale. Frequency data published
by Cosic et al. (2016) were used as an
example to show how the GM-scale can be
applied to evaluate such data in order to
label experimental or published EMF
frequencies as potential coherent or
decoherent .
3. Results
1. What is the significance of the
difference between coherent and
decoherent data sets?
The distribution of the frequency
data, transposed to the GM-scale of 1-2
Hz is presented in Table 3 and Figure
2.
The results of the Wilcoxon rank
sum test are presented in Table 4 and
in a boxplot representation in Figure
3.
All “coherent’ groups were shown
to be significantly different from the
“decoherent’ groups with a significance
of p<0.0025.
2. What is the congruency of
‘coherent’ and ‘decoherent’ data with
the GM-scale values, based on
frequency intervals?
The ‘coherent’ and ‘decoherent’
intervals are presumed to be equally
wide on a logarithmic scale, resulting in
the boundaries around the GM-values
presented in Table 5.
Comparison of the 2 datasets with
respect to these intervals is shown in
Figure 4 and 5 and Table 6 and 7.
It can be seen that almost 90% of
the data presumed to be ‘coherent’
actually fall in the ‘coherent’ intervals of
the GM-scale and 83.4% of the
‘decoherent’ data are located in the
‘decoherent’ intervals.
3. What is the congruency of
‘coherent’ and ‘decoherent’ data with
GM-scale values based on population
equality tests?
Theoretical GM-scale groups of 100
points each were created having a
normal distribution around each GM-
scale value for both the ‘coherent’ GM-
scale (X1-X12) and the ‘decoherent’
GM-scale (X’1-X’12). The SD for each
data group is calculated based on the
assumption of 90% probability in each
interval as shown in Table 8.
The ‘coherent’ data groups, C1 to
C12 (Table 3) were compared with the
‘coherent’ theoretical GM-scale groups
(X1-X12) and the ‘decoherent’ data
groups (D1-D12, Table 3) with the
‘decoherent’ theoretical GM-scale groups
(X’1-X’12). Results of the Wilcoxon
rank sum test (p<0.05) are presented in
Table 9.
4. How to apply the GM-scale to
evaluate experimental data in a
prospective manner?
Test 2 was selected to demonstrate
how the GM-scale can be applied to
evaluate the frequency data published
by Cosic et al. (2016).
In this publication Cosic presents
Characteristic Resonant Recognition
Model (RRM) frequencies for different
biological functions of protein- and
DNA-macromolecules, that she
converted to the corresponding EM-
radiation wavelengths.
Quantum Biosystems | 2019 | Vol 10 | Issue 2 | Page 33 51 38
Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
www.quantumbiosystems.org
Table 3. ‘Coherent’ and ‘Decoherent’ datapoints from reference (Geesink & Meijer, 2018c) grouped to the
GM-scale values.
Each group (‘coherent’C1-C12, ‘decoherent’ D1-D12) consists of N datapoints around the ‘coherent’ (green) or
‘decoherent’ (orange) GM-scale values, using the middle between 2 values on a logarithmic scale as borders to
determine to which group a data point belongs. For each group the mean, median, standard deviation is calculated
as well as the difference between mean and GM-scale value, represented in absolute value and as percentage of
the GM-scale value
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Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
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Figure 2. Distribution of data compared to GM-scale value boundaries. Each dot is a frequency obtained from
literature transposed to a value between 1 and 2 Hz. “Coherent frequencies are represented as green dots
decoherent frequencies as red dots. The y-axis is a vertically spreading axis to visualize the particular points.
Table 4. Results Wilcoxon rank sum test, “coherent’ vs “decoherent’ and vv.
Columns 1 and 3 show groups compared (Table 3). Columns 2 and 4 the results of the Wilcoxon rank sum test. A
value of p<0.01 is taken as statistically different. For the last comparison, the left sided comparison of C12 with
D1, all values of D1 were multiplied with 2.
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Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
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Figure 3 a b. Boxplots of coherent and decoherent dataset 1-6, vs GM-scale value (green*). On each box, the
central mark (red) indicates the median, and the bottom and top edges of the box indicate the 25th and 75th
percentiles, respectively. The whiskers extend to the most extreme data points not considered outliers, and the
outliers are plotted individually using the '+' symbol. If the notches in the box plot do not overlap, you can
conclude, with 95% confidence, that the true medians do differ.
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Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
www.quantumbiosystems.org
Figure 3 c d. Boxplots of coherent and decoherent dataset 6-12, vs GM-scale value (green*). On each box, the
central mark (red) indicates the median, and the bottom and top edges of the box indicate the 25th and 75th
percentiles, respectively. The whiskers extend to the most extreme data points not considered outliers, and the
outliers are plotted individually using the '+' symbol. If the notches in the box plot do not overlap, you can
conclude, with 95% confidence, that the true medians do differ.
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Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
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Table 5. Frequency intervals and boundaries of the GM-scale between 1 and 2 Hz.
‘Coherent’ GM-scale values are represented in green, ‘Decoherent’ GM-scale values in orange, interval boundary values
are represented in white. The first ‘decoherent’ interval is thus from 0.9617 to 0.9871 Hz; the first ‘coherent’ interval is
from 0.9871 to 1.0131 Hz; the second ‘decoherent’ interval is from 1.0131 to 1.0399 Hz; the second ‘coherent’ interval is
from 1.0399 to 1.0709 Hz; and so on. To transpose to other frequency ranges the values in the Table can be multiplied by
2m (see Table 1) or alternatively, experimental data can be transposed to a value between 1 and 2 Hz by dividing by 2m.
Bandwidth is the difference between interval boundaries (white)/GM-scale value (green or orange), e.g. for GM-scale (1)
(1.0131-0.9871)/1.0000=2.6%.
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Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
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Figure 4. Distribution of coherent data, including coherent frequencies that are able to inhibit and retard cancer, over
the GM-scale intervals of Table 5. Values are presented as percentage of total, absolute values can be found in Table 6.
Table 6. Distribution of the ‘coherent’ data over the intervals of Table 5.
For each GM-scale step or tone, the number of data points falling in the ‘Coherent’ (Coh int) or ‘Decoherent’ (Decoh int)
interval are represented. This is done for the original ‘coherent’ data set of reference (Geesink & Meijer, 2018c) (Coh
dataset), as well as the frequency data from literature that are able to inhibit and retard cancer (Cancer Coh) (Geesink &
Meijer, 2018c). Sum Coh is the sum of both Coh dataset and Cancer Coh per step and interval.
Quantum Biosystems | 2019 | Vol 10 | Issue 2 | Page 33 51 44
Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
www.quantumbiosystems.org
Figure 5. Distribution of decoherent data, including decoherent frequencies that can initiate and promote cancer, over
the GM-scale intervals of Table 5. Values are presented as percentage of total, absolute values can be found in Table 7.
Table 7. Distribution of ‘decoherent’ data over the intervals of Table 5.
For each GM-scale step or tone, the number of data points falling in the ‘Coherent’ (Coh int) or ‘Decoherent’ (Decoh int)
interval are represented. This is done for the original ‘decoherent’ data set of reference (Geesink & Meijer, 2018c)
(Decoh dataset), as well as the frequency data from literature that can initiate and promote cancer (Cancer Decoh)
(Geesink & Meijer, 2018c). Sum Decoh is the sum of both Decoh dataset and Cancer Decoh per step and interval.
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Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
www.quantumbiosystems.org
Table 8. Values used to generate theoretical GM-scale populations
‘Decoherent’ values are depicted in orange, ‘Coherent’ values in green. A ‘coherent’ population on the first ‘coherent’
GM-scale value (1.000) is generated assuming that values are normally distributed and 90% of the values are positioned
between 0.974 and 1.026 equaling an SD of SD(1)=(1.026-0.974)/(2*1.64)=0.0159 . A ‘decoherent’ population on the
first ‘decoherent’ GM-scale value (0.974) is generated assuming that values are normally distributed and 90% of the
values are positioned between 0.9492 (Table 5) and 1.000 equaling an SD of SD(1’)=(1.000-0.949)/(2*1.64) =0.0155.
Other SD’s are calculated in the same way.
A. “Coherent’ B. “Decoherent’
Table 9. Result of Wilcoxon rank sum experimental data comparison with theoretical GM-scale populations.
A. Comparison of theoretical generated populations X1-X12 with data groups C1-C12 (Table 3) per GM-scale step, p-
value, and hypothesis based on p<0,05 for non-equality. Hypothesis 0 is equal, 1 is non-equal
B. Comparison of theoretical generated populations X’1-X’12 with data groups D1-D12 per GM-scale step (Table 3), p-
value, and hypothesis based on p<0,05 for non-equality. Hypothesis 0 is equal, 1 is non-equal
Quantum Biosystems | 2019 | Vol 10 | Issue 2 | Page 33 51 46
Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
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Figure 6. Distribution of Cosic data compared to GM-scale value boundaries x-axis (Table 5). Each dot is a
frequency obtained from (Cosic et al., 2016), see Table 10. These values were transposed to a value between 1 and
2 Hz. The y-axis is an arbitrary value to visually discriminate between points. Color coding is taken from Cosic’s
distribution of functional groups over super families (Cosic et al., 2016).
Using the velocity of light
(c=299792458 m/s) these wavelengths (λ)
can easily be converted to frequencies
(f=c/λ). Frequencies are then transposed
to a value between 1 and 2 Hz, by dividing
by 2m. Frequency data and their converted
GM-scale values are presented in Table
10.
The transposed frequency values can be
plotted in a GM-scale diagram as shown in
Figure 6 and frequency values in
coherent and decoherent intervals can
be determined. As shown in Figure 6 and
7 and Table 10 the published frequency
data of Cosic seem to be about equally
distributed over coherent and
decoherent intervals.
4 . Discussion
Division of data between ‘coherent’
and ‘decoherent’ and grouping according
to the GM-scale values, resulted in 2 x 12
groups of data, C1-C12 and D1-D12.
Statistical analysis shows that all of the so-
called ‘coherent’ data groups are
statistically different from the ‘decoherent’
groups (p<0,0025). This strongly
supports the hypothesis of the assumed
division between ‘coherent’ and
‘decoherent’ frequencies, as proposed by
Geesink and Meijer.
Considering the fact that the data is
obtained from such a wide variety of
biological studies and spans ranges of Hz
to THz, this truly is a remarkable
discovery.
With respect to the fit to the
theoretical algorithm it can be seen that
mean values of the data groups are almost
equal to the GM-scale values
(difference<0,9%, Table 3, Figure 3).
As can be seen in Figure 1 and 2,
there is some overlap between ‘coherent’
and ‘decoherent’ datapoints.
This is quantified by introducing
alternating ‘coherent’ and ‘decoherent’
intervals, assuming boundaries in the
middle between each interval. 11% of
‘coherent’ data were found in ‘decoherent’
intervals and 17% of ‘decoherent’ data
were found in ‘coherent’ intervals, hinting
at a prediction accuracy of almost 90%,
based on current data.
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Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
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Table 10. Resonant Frequency Data of Cosic (Cosic et al., 2016) vs GM-scale (Continued on next page)
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Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
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Table 10. Resonant Frequency Data of Cosic (Cosic et al., 2016) vs GM-scale (Continued)
The data are obtained from reference (Cosic et al., 2016) “Table 1. Characteristic Resonant Recognition Model
(RRM) frequencies for different biological functions of protein and DNA macromolecules.” Column 1 represents
name of functional group of proteins and DNA. Column 2 represents the numerical RRM frequency. Column 3
represents the corresponding electromagnetic radiation in nm. Column 4 is the corresponding frequency of the
electromagnetic radiation of Column 2 in Hz. Column 5 is the transposed frequency between 1 and 2 Hz of the
frequency of Column 4. Column 6 is the assignment of the frequency based on their position in the intervals of
Table 5, 1= ‘coherent’ (green), 0=decoherent (white). E.g. Hemoglobin has RRM-frequency 0.0234 corresponding
to 20,000 nm or 1.5*1013Hz, transposed by division /243=1.7041, which is in the ‘coherent’ interval 10 (1.660-
1.710), and thus assigned ‘coherent’=1 (green).
Figure 7. Distribution of Cosic’s data over the GM-scale intervals of Table 5.
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It should be noted, when using these
scale intervals (Table 5) , that the band
widths of the particular GM-scale band
values are very small (2,6%-3,3% of scale
values). This has implications for the
accuracy of frequency values to be
evaluated since relatively small error
margins could already lead to a false
assignments. A considerable amount of
points are found on, or near, interval
boundaries, which suggests that
optimization of interval boundaries or
small alterations in GM-scale value
definitions could improve results.
An alternative way to test how well
the coherent data groups C1-C12 fitted
the GM-scale, was designed by creating
theoretical GM-scale groups around each
GM-scale value and evaluating
congruency of experimental data with
these theoretical data groups. In creating
these theoretical groups a normal
distribution was assumed and SD was
calculated based on 90% probability
around the coherent GM-value, using
decoherent values as boundaries.
Despite the close fit of data group mean
values with GM-scale values, difference
was apparently still such that only 9
coherent groups were found equal to
their respective theoretical GM-scale
groups. This indicates that differences
are very subtle and emphasizes
importance of accuracy of data.
Prospective use of the frequency
band spectrum to label EM
frequencies as being in the range of
coherency or decoherency
The GM-scale algorithm can be
applied to evaluate EMF data, or
prospectively choose EM frequencies, on
their beneficial (coherent) or
detrimental (decoherent) effects.
Based on current test results,
frequencies can best be evaluated using
the alternating coherent/decoherent
scale intervals (bands). How to apply the
GM-scale in this analysis is demonstrated
on the frequency data published by Cosic
et al.(2016) In this work she states that
her Resonant Recognition Model (RRM)
proposes to identify characteristic EM
frequencies involved in tumor regulation
(Murugan, Rouleau, Karbowski, &
Persinger, 2017), cell growth control
(Cosic, Drummond, Underwood, &
Hearn, 1994), vaccine development
(Krsmanovic et al., 1998), and
interference with infections such as
malaria (Cosic, Caceres, & Cosic, 2015)
and Ebola (Murugan, Karbowski, &
Persinger, 2015).
Unfortunately, no distinction was
made by Cosic between potential harmful
and beneficial effects of the frequency
values obtained. Based on the GM-scale
analysis 50% of frequencies are predicted
‘coherent’, having beneficial effects and
50% are predicted ‘decoherent’ having
harmful effects. A possible explanation
could be that Cosic’s goal is to identify
frequencies that effect certain proteins,
regardless of whether the effect on life
conditions is positive or negative.
For example, proteins that promote
inflammation, immune reactions or
programmed cell death can both be
interpreted as life sustaining and
detrimental for life.
An alternative explanation for this
ambivalent result could lie in the
required accuracy for a prediction. In the
conversion of theoretical RRM-
frequencies to real wavelengths
[2]
an experimentally derived factor (K=201)
is used which has a standard deviation of
15% (Cosic, 1994), far greater than the
interval band widths used in the GM-
scale.
In this article, apart from the
statistical analysis, a prospective method
is presented to further substantiate the
pattern of ‘coherent’ and ‘decoherent’
frequencies and the GM-scale algorithm.
Using this method, predictions with
respect to harmful or beneficial effects of
EMF can be made and evaluated.
Outliers can be identified and further
examined in detail to find explanations
for the discrepancy, which can lead to
new insights in biophysical mechanisms.
Quantum Biosystems | 2019 | Vol 10 | Issue 2 | Page 33 51 50
Trudi Sonderkamp, Hans J H Geesink and Dirk K F Meijer
ISSN 1970-223X
www.quantumbiosystems.org
In general, we realize that further
analysis of more experimental data with
respect to the fit to GM-scale values will
help to further validate this potentially
new biophysical principle. The ultimate
test will be a dedicated experimental
study set up that systematically evaluates
the effects of carefully selected individual
or combined series of GM-scale
frequencies on well standardized in-vivo
and in-vitro test systems.
5. Conclusions
The GM-scale presented in this
study is an attractive EMF distribution
pattern with the potential to distinguish
between beneficial (coherent) and
detrimental (decoherent) EM-
frequencies for life conditions.
A Wilcoxon rank sum population
analysis confirms that coherent and
decoherent data groups obtained from
literature are statistically different for all
12 GM-scale groups (p<0,0025).
The mean of the data groups almost
perfectly fit to the GM-scale values
(difference<0,9%). Based on 24
alternating coherent-decoherent GM-
scale frequency intervals 90% of
coherent data and 87% of decoherent
data are correctly predicted. The
difference between coherent and
decoherent frequencies is quite subtle;
band widths and therewith respective
error margins, are very small (2,6%-
3,3%).
A method is presented for
prospective application of the GM-scale
using these alternating frequency
intervals. These, and future, analyses of
experimental data with respect to the fit
of their EM frequencies to the GM-scale
will help to further validate this
algorithm as a new biophysical principle.
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I. Appendix 1. Literature data
from ref (Geesink & Meijer, 2018c)
Appendix Tabel 1 : The complete list
of EMF frequency data analyzed in the
present publication can be
directly provided by the first author
(please mail:
t.sonderkamp@kpnmail.nl).
... The discrete eigenfrequency values can be related to solitons or called polaron quasi particles; bio-solitons are conceived as self-reinforcing solitary waves that are constituting local fields, being involved in intracellular geometric ordering and patterning, as well as in intra-and inter-cellular signalling. The metanalysis of the spectra could be substantiated by a statistical analysis (Sonderkamp, 2019). ...
... Green lines: coherent frequencies; red lines: decoherent frequencies; yellow lines: transition frequencies. Nimustine added to DNA shows an increase from coherent to more decoherent frequency patterns (Geesink, 2019). (reference Bentley et al. 2007). ...
... (Kong, 2007). Remark: Coherent frequencies depicted as green, decoherent frequencies as red, and transition frequencies as yellow (Geesink, 2019). ...
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... All this, resulted in over 30 publications in largely varying research areas, all showing the distinct distribution of EMF bands as shown in the present study. We are confident therefore that our meta-analyses data are a reliable and faithful representation of the literature involved (Sonderkamp et al., 2019). ...
... A very interesting and complementary study on the physical structure of musical harmony was recently put forward by Berezovsky, 2019, in particular addressing the relation between Coherence and Decoherence in the creation of musical patterns. We have earlier speculated on the impact of decoherent states on quantum physical wave propagation in quantum biology and superconduction (Geesink and Meijer, 2019). The paper of Bereskovsky elegantly highlights this item and the following section is a short compilation of this work, summarizing this groundbreaking article as presented in the present compiled text from parts of this paper: ...
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... The entire fractal pattern can be easily calculated by expanding to lower and higher frequency ranges by multiplication or division by a factor 2. This provides an octave hierarchy of self-similar extensions of the scale. Multiplying this value with the octave hierarchy of 2, up to the THz-range (10^12 Hz), a range can be found where the biophysics of ordering of water molecules, relevant for life conditions, is at stake (Geesink and Meijer, 2019). It is of interest that the boundaries of the GM frequency spectrum, apart from IR and visible part of the spectrum, also lie in the far-infrared EM region, that occupies a middle ground between microwaves and infrared light waves, known as the "terahertz gap". ...
... In relation to its scale-invariant global character, extensive support was found for a universal (cosmic) information matrix (Meijer, 2019). The presence of such a field-receptive resonant workspace may therefore provide an interpretation framework for widely reported, but poorly understood transpersonal conscious states ( The human brain may receive quantum wave information directly derived from the Planck space-time level (left above) through quantum gravity mediated wave reduction, as well as through resonance with the ZPE field (right above). ...
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Meta-analysis of current biomedical and biophysical literature revealed the presence of a fractal pattern of discrete EMF frequency bands, in a wide range of animate and non-animate systems, framed as the Generalized Music (GM)-scale biophysical principle and also applied by us to study cognitive brain function as well as quantum mechanical aspects of first life. In this respect, it is proposed that nature is guided by a resonating set of quantum vacuum fluctuations of an all-pervading zero-point energy (ZPE)-field. It was shown that the toroidal GM-code can accommodate 4 spatial dimensions, in line with the Kaluza Klein concept as a feature of the Sub-Quatum SFQS, conceived as a homogenous 5-D space-time manifold. The related photon/phonon and soliton fluxes can be modelled by toroidal geometry as also obtained from Perelmann-Ricci-Flow mappings, processes that enable crucial wave damping and tone separation. The GM-scale exhibits a self-similar fractal) wave pattern that gives rise to a series of more than 500 EMF frequencies from the Hz to the GHz ranges, thereby exhibiting a field-like character. In this paper we report on a series of 46 experimentally determined ZPE-frequencies, from 15 separate studies, that fit the GM-scale eigenvalues closely. The central message of these quantum wave studies implies a cosmic connectivity operating in a primordial context, possibly related to known bounce models of our universe, that is likely also mirrored in life processes, including the human brain. It is postulated that the generation of life in the cosmos resulted from a symmetry breaking from the homogenous 5-D manifold that contains condensed boson type of quantum wave information and is instrumental in past/future transactional information processing and/or pilot-wave type of wave guiding. In this sense, the ZPE-field is seen as a transition zone from the 5D Sub-Quantum domain to our quantum world. We hold that the ZPE-field presents an all-pervading quantum field, that provides long-distance solitons (electron-phonon quasi-particles) that can guide the 3D folding of brain macromolecules embedded in coherently structured water domains, in which hydronium ions and Ca2+ ions are particularly instrumental. In this manner cell proteins and DNA may function as wave-antennas to receive active life-information for the functional architecture of cell, and the generation of cell memory and conscious states. For the permanent transmission of external information a holographic 5D memory workspace of the brain is required that is associated with, but not reducible to the brain. This field-sensitive holographic workspace is involved in predictive coding and quality control of individual awareness. Recent studies by Wong et al., show that the creation of life can be conceived as being guided through a symmetry breaking of condensed (charge neutral, massless) bosons from the 5D informational manifold. The particuar "Diagonal Long Range Ordered" bosons represent the monopoles from the Maxwell magnetic monopole potential, a solitonic eigenstate of the homogenous 5-D manifold, that through Perelmann mapping generates toroidals, instrumental in the formation bio-rings including the nitrogenous bases of RNA and DNA. The retained EMF from these monopole bosons within the RNA and DNA can interact with the molecular entities of life, such as H2O, carbon and nitrogen, by inducing mobile positive valence band hole charges in the molecules. This provides an off-diagonal-long-range ordered superconducting phase that enables cell grow and survival in its thermal environment. It is finally concluded that all matter, from galaxies through life creation therein, is derived from scale invariant information transfer, expressed at the holographic event horizons of each individual cosmic entity, a process that was intended to be verified and observed by the intelligent subjects of its own creation.
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In this chapter, we postulate an integral concept of information processing in the universe, on the basis of a new biophysical principle, coined the generalized music (GM)-scale of EMF frequencies. Meta-analyses of current biomedical literature revealed the presence of a distinct pattern of discrete EMF frequency bands in a wide range of animate and non-animate systems. The underlying algorithm of harmonic solitonic waves provided a novel conceptual interface between living and non-living systems being of relevance for the areas of brain research as well as biological evolution. We hold that nature is guided by resonating quantum entities related to quantum vacuum fluctuations of an imminent zero-point energy (ZPE) field, also regarded as a superfluid quantum space (SQS). Since the whole human organism, including the brain is embedded in this dynamic energy field, a pilot wave guided supervenience of brain function is conceived. Conversely, the brain may write discrete informational states into the ZPE- field as individual memory traces. Both information fluxes may be related to a holofractal memory workspace, associated with, but not reducible to the brain, that operates as a scale-invariant mental attribute of reality. Our concept, therefore, addresses the earlier postulated “hard problem” in consciousness studies. The proposed field-receptive workspace, integrates past and (anticipated) future events and may explain overall ultra-rapid brain responses as well as the origin of qualia. Information processing in the brain is shown to be largely facilitated by propagation of hydronium (proton/water) ions in aqueous compartments. The hydronium ions move freely within a hexagonally organized H2O lattice, providing a superconductive integral brain antenna for receiving solitonic wave information, according to the Schrödinger wave equation. The latter quantum process enables an ultra-rapid soliton/biophoton flux that may orchestrate overall brain binding and the creation of coherent conscious states. In a cosmological context, we envision a scale-invariant information processing, operating through a toroidal/wormhole operator at the interface of our 3D world and a 4D acoustic phase space. We submit that the resulting meta-language is instrumental in a partially guided evolution and the creation of first life. This implies that sentience exists on infinite scales, on the basis of an electromagnetic signature of the universe providing an intrinsic cosmic connectivity that is mirrored in the human brain and that we may experience as a vivid dream of a concealed reality. Humans, in this respect, are not only observers but also active participants in this cosmic endeavor: the evolution of conscious entities has been woven into the cosmic mastercode from the beginning. The main thesis of this chapter is that in science and philosophy the dominant paradigm of materialism should be considered as incomplete for explaining the whole of reality.
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This paper addresses the question whether superconductive phenomena in superconductive materials and in life systems have common physical grounds. An extensive literature survey was performed with regard to intrinsic energy gap frequencies reported on a range of superconductor materials as measured by different spectroscopic technologies. The registered frequencies were plotted on an acoustic scale and compared with earlier detected EM frequency patterns revealed in various life systems. A meta-analysis showed that the particular wave frequency patterns in superconducting materials have discrete coherent frequency bands and are very much in line with those found in biological systems. We hypothesize that the revealed individual frequencies either alone or in combination provide a means to select or identify materials that exhibit superconductive properties at elevated critical temperature ranges. We propose that the spectral energy gaps of superconducting materials can be positioned at the pointer states of a pattern of coherent frequencies, and can be described by an acoustic algorithm, coined by us the GM-biophysical principle. High Temperature Superconductors (HTSC's) show patterns of frequencies, in which frequency ratios of 2:3 (third harmonic) are incorporated in ratios of 1:2 (fundamental frequency). We propose to apply semi-conductive smectites (phyllosilicates), studied in detail by us earlier, that radiate GM-like EMF frequencies, in combination with HTC superconductor materials, to further improve superconductive properties as a modality of intrinsic quantum lasing. Our observations highlight a potential quantum bridge between superconducting properties in physics and biology.
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In 1905 Einstein proposed the idea that electromagnetic radiation is quantized and appears only in defined energy packets. The energy of a photon for a given type of radiation can be computed using the frequency relation published in 1900 by Planck. It is proposed in the present paper that the energy distribution of these packets is according to a Pythagorean distribution of frequencies. Evidence for this hypothesis has been found by a meta-analyses of 500 biomedical papers related to electromagnetic frequencies of living cells and bio-molecules, in addition to an analyses of 60 papers in physics that deal with the influence of electromagnetic frequencies on the promotion of entangled states in Einstein, Podolsky and Rosen-experiments, as well as a study on measurements of the masses of 37 different elementary particles. It turns out that Einstein was right, and that electromagnetic radiation is quantized according to a precise distribution of defined energy packets.
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The underlying rules for a natural system describing cellular automata are simple, but produce highly complex behavior. A mathematical basis for the spectra of discrete coherent and non-coherent electromagnetic (EM) frequencies was derived, in which the algorithm exhibits an information distribution according to ratios of 2:3 in 1:2 at a semi-harmonic manner. This generalized music (GM) model shows that energy both in elementary particles and animate systems is semi-harmonic, quantized and discrete. A support for an ontological basis of the Standard Model was found, and indicates that the GM-model underlies the quantum field theory of subatomic particles. The present theory combines quantum mechanics and classical periodic systems, obeys to locality and solves the “hidden variable theory of Bohm”. The discovered pattern of electromagnetic field eigenvalues, within a broad range of discrete frequencies, points at a de Broglie/Bohm type of causal interpretation of quantum mechanics, implying an integral resonant pilot-wave/particle modality. The model has been substantiated by a meta-analysis of measured discrete energies of: 37 different Elementary Particles, 45 different EPR-measurements, zero-point energies of elements and about 450 electromagnetic wave frequencies of cells with a mean accuracy of 0.58%. It has been shown that the GM-scale is frequency-locked with zero-point oscillations, and thereby evidently implies involvement of entanglement.
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Abstract Carcinogenesis fits in a frequency pattern of electromagnetic field (EMF) waves, in which a gradual loss of cellular organization occurs. Such generation of cancer features can be inhibited by adequate exposure to coherent electromagnetic frequencies. However, cancer can also be initiated and promoted at other distinct frequencies of electromagnetic waves. Both observations were revealed by analyzing 100 different EMF frequency data reported in meta-analyses of 123 different, earlier published, biomedical studies. The studied EM frequencies showed a fractal pattern of 12 beneficial (anti-cancer) frequencies, and 12 detrimental (cancer promoting) frequencies, that form the central pattern of a much wider self-similar EMF spectrum of cancer inhibiting or promoting activities. Inhibiting of the cancer process, and even curing of the disease, can thus be considered through exposure to the coherent type of EM fields. Stabilization of the disease can be understood by constructive resonance of macromolecules in the cancer cell with the externally appied coherent EMF field frequencies, called solitons/polarons. The latter, for instance, have been shown earlier to induce repair in DNA/RNA conformation and/or epigenetic changes. The field of EMF treatment of cancer disorders is rapidly expanding and our studies may invite further experimental and clinical studies in which systematically various potential EMF treatment protocols could be applied, with combined and modulated frequencies, to obtain even more efficient EMF anti-cancer therapies.
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Solitons or polarons, as self-reinforcing solitary waves, interact with complex biological phenomena such as cellular self-organization. Such soliton models are able to describe a spectrum of electromagnetism (EM) modalities, that can be applied to understand the physical principles of biological effects in living cells, as caused by endogenous and exogenous electromagnetic fields, on the basis of quantum coherence. A bio-soliton model was earlier developed by us, that enables to predict which eigen-frequencies of non-thermal EM waves, are life-sustaining and which are, in contrast, detrimental for living cells. The particular effects of the proposed coherent wave pattern are exerted by a range of EM-wave eigen-frequencies of one-tenth of a Hertz till Peta Hertz, representing a pattern of twelve bands, that can be positioned on an acoustic frequency scale. The discrete pattern was revealed by a meta-analysis of 219 published papers of biological EM-radiation experiments, in which a spectrum of non-thermal EM fields were exposed to living cells and intact organisms. In follow-up studies, we analyzed 120 articles on cancer-promoting and inhibiting EM fields, of which the frequency patterns fully confirmed the inferred model. Finally we analyzed experimental data out of 27 recent publications on laser mediated radiation therapy, for a spectrum of disorders such as traumatic brain injury, depressive disorders and neurological defects, confirming the general predictive force of our life algorithm. It is postulated that long-distance control of cellular morphology and fine tuning of cellular networks by soliton-waves, is instrumental in providing a morphogenetic field that maintains cellular health. The latter also may have played a role in the initiation of first life in biological evolution. The particular parametric resonance may provide positional information and cues to regulate organism-wide system properties like anatomy, control of reproduction as well as gene expression and repair. In addition, potential damaging effects of non-ionizing electromagnetic fields on life systems can be counteracted by dedicated phyllosilicate (clay) nano-materials, that were shown by us to exhibit semi-conducting EM field properties. A related protective technology was designed on the principle of toroidal trapping, since torus geometry adequately generates a coherent field of frequencies and thereby induces coherent oscillations of macromolecules. Our papers, collectively, picture the rapidly growing and dynamic field of molecular electromagnetics, that currently shows promising clinical effects in the treatment of various sincere, and often, chronic diseases. The discovered frequency patterns might be interpreted as hidden variables in Bohm's causal interpretation of quantum mechanics theory. The life algorithm detected and called by us the GM-scale, may highlight a presently unknown bio-physical (de)stabilizing principle that underlies (de)coherence of quantum wave oscillations in animate and also some non-animate systems.
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Recently, a novel biological principle, revealing specific electromagnetic (EM) radiation frequencies that sustain life, was presented by us on the basis of an evaluation of 175 biological articles concerning beneficial effects of electromagnetic waves on the state of living cells. This concept was also based on a very similar range of frequencies emitted by a clay-mineral catalyst of RNA synthesis that may have been instrumental in the evolutionary initiation of first life, and therefore was tentatively designated as “Algorithm of Life”. The particular spectrum of frequency bands indicate that nature seems to employ discrete eigenfrequencies or standing waves that match precisely with an acoustic scale, with frequency ratios of 1:2, and closely approximated by 2:3, 3:4, 3:5, 4:5 and higher partials, allowing the discrete frequencies to be expressed in scalars. Our further studies clearly indicate now that this “life algorithm” pattern matches very well with the mathematical calculations of W. Ritz (1909) to compute eigenfrequencies of the sound induced geometric patterns. These have been earlier demonstrated through membrane vibration experiments of E. Chladni (1787), as well as several follow up studies from 1970-2013. Our findings, therefore, touch upon the science of acoustics, also since we show that the discrete frequencies could be modeled by music torus geometry. We postulate that the spectrum of EM frequencies detected, exhibit a quantum ordering effect on life cells on the basis of induction of geometric wave patterns. These constitute phonon/photon and electron wave energies, and quantum oscillations at far-infrared frequencies, that are communicated through toroidal constructive interference into scalar wave information. This idea is supported through our identification of potential intrinsic toroidal eigenfrequencies and minimal energy levels. The particular torus topology for information processing may also provide quantum error correction and protection against decoherence. Finally, we propose a phonon guided organization of cells and integral brain function by three elementary processes: 1) A phonon mediated geometric organization of coherent arrangement of water molecules in cellular plasma, leading to instructive functional organization of cellular structures and metabolic processes and enabling the origination and sustainment of life processes. 2) Toroidal phonon/photon/electron coupling, protecting standing wave coherency of resonant cell components such as proteins and DNA. 3) A toroidal integration of electromagnetic and phononic fluxes of information into scalar standing waves, promoting quantum flux of informational excitons such as Ca2+- ions and electrons (polaron and polariton formation). Our brain, therefore, can be placed in a 4+1 geometry, supported by internal and external quantum states and makes use of geometrical defined information fluxes, that are converted to standing waves. The integration of these interrelated processes is considered to be instrumental in the creation of conscious perception and is proposed to be organized in a fractal, nested, 4-D toroidal geometry