In this paper, an analysis is made for heat transfer unsteady flow of nanofluid over semi-infinite vertical plate with leading edge accretion/ablation. The impact of viscous dissipation in energy equation with Newtonian heating condition is also considered. Tiwari-Das model is used to incorporates the effects of nanoparticles volumetric fraction. Sodium carboxymethyl cellulose (SCMC) is considered as based fluid containing titania (TiO 2 ) nanoparticles. Similarity transformations are employed to transform the unsteady partial differential equations into a system of ordinary differential equations. The transformed equations along with relevant boundary conditions are solved numerically by Runge Kutta Fehlberg fourth-fifth order (RKF45) method in MAPLE software. The analysis shows that velocity and temperature field in the respective boundary layers depend on different physical parameters, namely Prandtl number, Eckert number, Casson parameter, Newtonian heating parameter, accretion/ablation parameter and nanoparticle volume fraction. Temerature shows higher value for Blasius flat plate, while for Rayleigh-Stokes is the lowest.