1. Haines PS, Guilkey DK, Popkin BM. Trends in
breakfast consumption of US adults between 1965
and 1991. J Am Diet Assoc 1996;96:464–70.
2. Deshmukh-Taskar P, Nicklas TA, Radcliffe JD,
O’Neil CE, Liu Y. The relationship of breakfast
skipping and type of breakfast consumed with
overweight/obesity, abdominal obesity, other
cardiometabolic risk factors and the metabolic
syndrome in young adults. The National Health
and Nutrition Examination Survey (NHANES):
1999-2006. Public Health Nutr 2013;16:2073–82.
3. Kant AK, Graubard BI. 40-year trends in meal
and snack eating behaviors of American adults.
J Acad Nutr Diet 2015;115:50–63.
4. van der Heijden AA, Hu FB, Rimm EB, van
Dam RM. A prospective study of breakfast con-
sumption and weight gain among U.S. men.
Obesity (Silver Spring) 2007;15:2463–9.
5. Farshchi HR, Taylor MA, Macdonald IA. Delete-
rious effects of omitting breakfast on insulin
sensitivity and fasting lipid proﬁles in healthy lean
women. Am J Clin Nutr 2005;81:388–96.
6. Smith KJ, Gall SL, McNaughton SA, Blizzard L,
Dwyer T, Venn AJ. Skipping breakfast: longitudinal
associations with cardiometabolic risk factors in
the Childhood Determinants of Adult Health
Study. Am J Clin Nutr 2010;92:1316–25.
7. Witbracht M, Keim NL, Forester S, Widaman A,
Laugero K. Female breakfast skippers display a
disrupted cortisol rhythm and elevated blood
pressure. Physiol Behav 2015;140:215–21.
8. Lee TS, Kim JS, Hwang YJ, Park YC. Habit of
eating breakfast is associated with a lower risk of
hypertension. J Lifestyle Med 2016;6:64–7.
9. Ballon A, Neuenschwander M, Schlesinger S.
Breakfast skipping is associated with increased risk
of type 2 diabetes among adults: a systematic
review and meta-analysis of prospective cohort
studies. J Nutr 2019;149:106–13.
10. Bi H, Gan Y, Yang C, Chen Y, Tong X, Lu Z.
Breakfast skipping and the risk of type 2 diabetes:
a meta-analysis of observational studies. Public
Health Nutr 2015;18:3013–9.
11. Odegaard AO, Jacobs DR Jr., Steffen LM, Van
Horn L, Ludwig DS, Pereira MA. Breakfast fre-
quency and development of metabolic risk. Dia-
betes Care 2013;36:3100–6.
12. Cahill LE, Chiuve SE, Mekary RA, et al. Pro-
spective study of breakfast eating and incident
coronary heart disease in a cohort of male US
health professionals. Circulation 2013;128:337–43.
13. Kubota Y, Iso H, Sawada N, Tsugane S,
Group JS. Association of breakfast intake with
incident stroke and coronary heart disease: the
Japan Public Health Center-Based Study. Stroke
14. National Center for Health Statistics. Plan and
Operation of the Third National Health and
Nutrition Examination Survey (NHANES III, 1988-
94): Reference Manuals and Reports: Weighting
and Estimation Methodology Report. Hyattsville,
MD: Centers for Disease Control and Prevention,
15. National Center for Health Statistics. National
Health and Nutrition Examination Survey: NHANES
Questionnaires, Datasets, and Related Documen-
tation. Available at: https://wwwn.cdc.gov/nchs/
nhanes/Default.aspx. Accessed January 28, 2012.
16. Ahluwalia N, Dwyer J, Terry A, Moshfegh A,
Johnson C. Update on NHANES dietary data: focus
on collection, release, analytical considerations,
and uses to inform public policy. Adv Nutr 2016;7:
17. National Center for Health Statistics, U.S.
Department of Health and Human Services.
NHANES III Reference Manuals and Reports (CD-
ROM). Hyattsville, MD: Centers for Disease Con-
trol and Prevention, 1996.
18. Plan and operation of the Third National
Health and Nutrition Examination Survey, 1988-
94. Series 1: programs and collection procedures.
Vital Health Stat 1 1994:1–407.
19. National Center for Health Statistics. NCHS
2011 Linked Mortality Files Matching Methodol-
ogy. Hyattsville, MD: Ofﬁce of Analysis and
20. World Health Organization. International Sta-
tistical Classiﬁcation of Diseases and Related
Health Problems: Tenth Revision. 2nd edition.
Geneva, Switzerland: World Health Organization,
21. Liangpunsakul S. Relationship between alcohol
intake and dietary pattern: ﬁndings from NHANES
III. World J Gastroenterol 2010;16:4055–60.
22. U.S. Department of Agriculture and U.S.
Department of Health and Human Services. 2015–
2020 Dietary Guidelines for Americans. 8 edition.
Washington, DC: U.S. Government Printing Ofﬁce,
23. Pate RR, Pratt M, Blair SN, et al. Physical ac-
tivity and public health. A recommendation from
the Centers for Disease Control and Prevention
and the American College of Sports Medicine.
24. Retnakaran R, Qi Y, Connelly PW, Sermer M,
Hanley AJ, Zinman B. Low adiponectin concen-
tration during pregnancy predicts postpartum in-
sulin resistance, beta cell dysfunction and fasting
glycaemia. Diabetologia 2010;53:268–76.
25. Whelton PK, Carey RM, Aronow WS, et al. 2017
NMA/PCNA guidelinefor the prevention, detection,
evaluation,and management of high bloodpressure
in adults: executive summary: a report of the
American College of Cardiology/American Heart
Association Task Force on Clinical Practice Guide-
lines. J Am Coll Cardiol 2018;71:2199–269.
26. Menke A, Casagrande S, Geiss L, Cowie CC.
Prevalence of and trends in diabetes among adults
in the United States, 1988-2012. JAMA 2015;314:
27. National Cholesterol Education Program
(NCEP). Expert Panel on Detection Evaluation, and
Treatment of High Blood Cholesterol in Adults
(Adult Treatment Panel III). Third Report of the
National Cholesterol Education Program (NCEP)
Expert Panel on Detection, Evaluation, and
Treatment of High Blood Cholesterol in Adults
(Adult Treatment Panel III) ﬁnal report. Circulation
28. Uzhova I, Fuster V, Fernandez-Ortiz A, et al.
The importance of breakfast in atherosclerosis
disease: insights from the PESA study. J Am Coll
29. Sharma K, Shah K, Brahmbhatt P, Kandre Y.
Skipping breakfast and the risk of coronary artery
disease. QJM 2018;111:715–9.
30. Most J, Tosti V, Redman LM, Fontana L. Cal-
orie restriction in humans: an update. Ageing Res
31. Ahmet I, Tae HJ, de Cabo R, Lakatta EG,
Talan MI. Effects of calorie restriction on car-
dioprotection and cardiovascular health. J Mol Cell
32. Alwattar AY, Thyf ault JP, Leidy HJ. T he effect
of breakfast typ e and frequency o f consumption
on glycemic response in overweight/obese l ate
adolescent girl s. Eur J Clin Nutr 2 015;69:
33. Astbury NM, Taylor MA, Macdonald IA.
Breakfast consumption affects appetite, energy
intake, and the metabolic and endocrine re-
sponses to foods consumed later in the day in
male habitual breakfast eaters. J Nutr 2011;141:
34. Reutrakul S, Hood MM, Crowley SJ,
Morgan MK, Teodori M, Knutson KL. The rela-
tionship between breakfast skipping, chronotype,
and glycemic control in type 2 diabetes. Chrono-
biol Int 2014;31:64–71.
35. Jovanovic A, Gerrard J, Taylor R. The second-
meal phenomenon in type 2 diabetes. Diabetes
36. Gwin JA, Leidy HJ. A review of the evidence
surrounding the effects of breakfast consumption
on mechanisms of weight management. Adv Nutr
37. Ahuja KD, Robertson IK, Ball MJ. Acute effects
of food on postprandial blood pressure and mea-
sures of arterial stiffness in healthy humans. Am J
Clin Nutr 2009;90:298–303.
38. Peitzman SJ, Berger SR. Postprandial blood
pressure decrease in well elderly persons. Arch
Intern Med 1989;149:286–8.
39. Park S, Rim SJ, Lee JH. Associations between
dietary behaviours and perceived physical and
mental health status among Korean adolescents.
Nutr Diet 2018;75:488–93.
KEY WORDS all-cause mortality,
cardiovascular mortality, skipping breakfast
Rong et al.JACC VOL. 73, NO. 16, 2019
Skipping Breakfast and Mortality APRIL 30, 2019:2025–32