Substances abuse are substances taken illegally and are listed under the 1952 Poisons Act such as kratom and are listed under the Dangerous Drugs Act 1952 such as heroin, opium, ketamine, methamphetamine, cannabis, and other substances that causes addiction or dependency physically or psychologically. This survey was carried out to study the awareness of Universiti Utara Malaysia (UUM) students on substance abuse. This study is a survey and is a quantitative study. A group of 159 students were randomly selected from the Creative Industry Management and Performing Arts programme (SCIMPA) in UUM. A study instrument in the form of a questionnaire from previous study was used. The collected data are then analyses using descriptive tests through the Statistical Package for Social Science (SPSS) version 22. The result showed that a majority of students had awareness on substance abuse and its effects on the users. Most of them also reported having awareness on the usage of kratom and cough medication. However, results also showed that the students had less awareness on the usage of prohibited substances such as opium, morphine, depressants and other hallucinogens because they seldom hear of these substances. Besides that, students are also aware of the negative effects of using prohibited substances. Hence, some suggestions are also discussed by the researcher regarding how to handle the issue of prohibited substances use in UUM campus so as to ensure the welfare of UUM students. © 2019, Indian Journal of Public Health Research and Development. All rights reserved.