Article

Effect of Aqueous and Ethanolic Extracts of Tribulus terrestris, Phoenix dactylifera and Nasturtium officinale Mixture on Some Reproductive Parameters in Male Mice

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Abstract

The present investigation was conducted to evaluate the effect of the crude extracts mixture of three plants (Tribulus terrestris, Phoenix dactylifera and Nasturtium officinale) on semen quality,sex hormones and reproductive performance of mature male mice. A group of 25 male mice given 150mg/kg/day of the powder of the plants mixture with the food for four weeks and another three groups of 25 animals each given intraperitoneal injection from each of the aqueous and ethanolic extracts with a doses 75, 150, and 300mg/kg/day for two weeks. A remarkable increase in sperm concentration and motility with a decreased abnormal morphology was obtained in the experimental groups. A significant increase in hormones level were recognized in most groups. The results of mating untreated females with treated males of the four experimental groups revealed a decreased gestation period and an increased litter size. The results showed a dose dependent pattern of activity and the effect of the extracts were enhanced with increasing the dose level. The ethanolic extract being the more effective extract in all parameters.

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... FSH will bind to the Sertoli cells to facilitate spermatogenesis in seminiferous tubules. Increasing sperm count at N. officinale with 100 mg/kg dose might be due to the significant increase in (Mattar & Adaay, 2012). The results of this study indicate that OM has been shown to increase the high levels of testosterone secretion (1.68 μIU/ml) compared with the control group (healthy,0.6 μIU/ml) as the extract of this plant has been modifying the level of the hormone. ...
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