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The recent developments of advanced models of unified physics have brought a deeper understanding of the fundamental nature of space, time, energy and matter. It is becoming apparent that information and geometry are primary to explaining these fundamental agents. In previous work, we demonstrated that the subatomic nucleon structure of the proton and recently the electron can be derived directly from a spacetime holographic structure of Planck-scale quantum vacuum oscillators fluctuating as spacetime pixels, demonstrating that spacetime at the very fine level of the Planck-scale is discrete with information quanta. We have found that when considering the granular spacetime information-energy structure from which we demonstrate matter and mass arises, the phenomena of self-organizing systems that leads to self-awareness and consciousness is integral to—and a naturalemergent property of the feedback-dynamics of spacetime information itself. In this work, we describe how the integral function of the information feedback dynamics of spacetime, which engender mass-energy, is the missing element in understanding the evolution and development of self-organizing physical systems in general, and the emergence of the biological organism in particular. We evaluate non-classical quantum mechanical phenomena of physical and biological systems in light of the Maldacena-Susskind holographic correspondence theorem from which an equivalence of wormhole spacetime geometry and quantum entanglement is derived. We suggest that the Planck-scale micro-wormhole entanglement structure of multiple spacetime coordinates engender the macromolecular assemblies of living cells, and that this wormhole-entanglement may function in the memory andlearning capacity of the biological entity. Furthermore, the recursive information encoding feedback processes of the quantum spacetime micro-wormhole network, which we refer to as spacememory, enables memory and learning in physical systems across all scales, resulting in universal evolutionary tendencies towards higher levels of ordering and complexity – foundational to evolution, sentience, and awareness.

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We find an exact quantized expression of the Schwarzschild solution to Einstein's field equations utilizing spherical Planck units in a generalized holographic approach. We consider vacuum fluctuations within volumes as well as on horizon surfaces, generating a discrete spacetime quantization and a novel quantized approach to gravitation. When applied at the quantum scale, utilizing the charge radius of the proton, we find values for the rest mass of the proton within of the CODATA value and when the 2010 muonic proton charge radius measurement is utilized we find a deviation of from the proton rest mass. We identify a fundamental mass ratio between the vacuum oscillations on the surface horizon and the oscillations within the volume of a proton and find a solution for the gravitational coupling constant to the strong interaction. We derive the energy, angular frequency, and period for such a system and determine its gravitational potential considering mass dilation. We find the force range to be closely correlated with the Yukawa potential typically utilized to illustrate the exponential drop-off of the confining force. Zero free parameters or hidden variables are utilized.

Yves Couder, Emmanuel Fort, and coworkers recently discovered that a millimetric droplet sustained on the surface of a vibrating fluid bath may self-propel through a resonant interaction with its own wave field. This article reviews experimental evidence indicating that the walking droplets exhibit certain features previously thought to be exclusive to the microscopic, quantum realm. It then reviews theoretical descriptions of this hydrodynamic pilot-wave system that yield insight into the origins of its quantumlike behavior. Quantization arises from the dynamic constraint imposed on the droplet by its pilot-wave field, and multimodal statistics appear to be a feature of chaotic pilot-wave dynamics. I attempt to assess the potential and limitations of this hydrodynamic system as a quantum analog. This fluid system is compared to quantum pilot-wave theories, shown to be markedly different from Bohmian mechanics and more closely related to de Broglie’s original conception of quantum dynamics, his double-solution theory, and its relatively recent extensions through researchers in stochastic electrodynamics.

A bouncing droplet, self-propelled by its interaction with the waves it
generates, forms a classical wave-particle association called a "walker."
Previous works have demonstrated that the dynamics of a single walker is driven
by its global surface wave field that retains information on its past
trajectory. Here, we investigate the energy stored in this wave field for two
coupled walkers and how it conveys an interaction between them. For this
purpose, we characterize experimentally the "promenade modes" where two walkers
are bound, and propagate together. Their possible binding distances take
discrete values, and the velocity of the pair depends on their mutual binding.
The mean parallel motion can be either rectilinear or oscillating. The
experimental results are recovered analytically with a simple theoretical
framework. A relation between the kinetic energy of the droplets and the total
energy of the standing waves is established.

This paper gives the 2006 self-consistent set of values of the basic constants and conversion factors of physics and chemistry recommended by the Committee on Data for Science and Technology (CODATA) for international use. Further, it describes in detail the adjustment of the values of the constants, including the selection of the final set of input data based on the results of least-squares analyses. The 2006 adjustment takes into account the data considered in the 2002 adjustment as well as the data that became available between 31 December 2002, the closing date of that adjustment, and 31 December 2006, the closing date of the new adjustment. The new data have led to a significant reduction in the uncertainties of many recommended values. The 2006 set replaces the previously recommended 2002 CODATA set and may also be found on the World Wide Web at physics.nist.gov/constants.

DNA Polymerases slide on DNA during replication and the interface must be mobile for various conformation changes. The role of lubricant interfacial water has not been understood. In this report, we systematically characterized the water dynamics at the interface and in the active site of a tight-binding polymerase (pol ) in its binary complex and ternary state using tryptophan as a local optical probe. Using femtosecond spectroscopy, we observed that upon DNA recognition the surface hydration water is significantly confined and becomes bound water at the interface, but the dynamics are still ultrafast and occur on the picoseconds time scales. These interfacial water molecules are not trapped but are mobile at the heterogeneous binding nanospace. Combining with our previous observation of ultrafast water motions at the interface of a loose-binding polymerase (Dpo4), we conclude that the binding interface is dynamic and the water molecules in various binding clefts, channels and caves are mobile and even fluid with different levels of mobility for loose or tight binding polymerases. Such a dynamic interface should be general to all DNA polymerase complexes to ensure the biological function of DNA synthesis.