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A Novel Treatment for Constipation by Sesame Seeds

Authors:

Abstract

The constipation is a condition that known as unable of patient to discharge the stool from the body. Moreover, there are many reasons for this is condition such as modern life style witch increase the pressure on individual to obtained wide range of needs which incased day by day. Moreover, low physical activates for prolonged time this is condition affecting many patients worldwide and led to reduced bowel movements, moreover, taking fast meals (sandwiches) most of it contains harden food. Consequently, all previous mentioned factors and other can resulting in more clasp of feces, failed or lengthy attempts go to the bathroom and a sense of incomplete emptying (evacuation). The objective: To determine the effect positive effects of sesame seeds constipation patients. The results: Our study revealed that taking Sesame seeds (mixed with some sugar) two times per day for three weeks lead to unbelievable results in evacuation without any problem and this might promising treatment for all patients suffering from chronic constipation. I believed that low water intake play a key role in constipation because most metabolism and enzymes needs enough water if there is no enough water most metabolism don't work properly lead to reduced food hydrolysis by right way and not absorb correctly and stack in bowel lead to many problems.
International Journal for Research in Applied Science & Engineering Technology (IJRASET)
ISSN: 2321-9653; IC Value: 45.98; SJ Impact Factor: 6.887
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©IJRASET: All Rights are Reserved 400
A Novel Treatment for Constipation by Sesame
Seeds
Dr: Hisham Mohamed Osman Ibrahim1
1Biochemistry, College of Medical laboratory Sciences, Jouf University
Abstract: The constipation is a condition that known as unable of patient to discharge the stool from the body. Moreover, there
are many reasons for this is condition such as modern life style witch increase the pressure on individual to obtained wide
range of needs which incased day by day. Moreover, low physical activates for prolonged time this is condition affecting many
patients worldwide and led to reduced bowel movements, moreover, taking fast meals (sandwiches) most of it contains harden
food. Consequently, all previous mentioned factors and other can resulting in more clasp of feces, failed or lengthy attempts go
to the bathroom and a sense of incomplete emptying (evacuation). The objective: To determine the effect positive effects of
sesame seeds constipation patients. The results: Our study revealed that taking Sesame seeds (mixed with some sugar) two times
per day for three weeks lead to unbelievable results in evacuation without any problem and this might promising treatment for
all patients suffering from chronic constipation. I believed that low water intake play a key role in constipation because most
metabolism and enzymes needs enough water if there is no enough water most metabolism don’t work properly lead to reduced
food hydrolysis by right way and not absorb correctly and stack in bowel lead to many problems.
Keywords: treatment, chronic constipation and sesame seeds.
I. INTRODUCTION
Constipation is affecting millions of peoples in worldwide which is define as gastrointestinal tract problem, which can result in the
low stools, difficult stool passage with pain and stiffness. Moreover, this is disease in some cases can led to closure of the intestine,
which may even require surgery [1].
There are many factory for constipation such as low fluid intake, aging, low physical activities, taking medication and high stress
life and genetic factors.
The feces, is considered as a solid bodily waste discharged from the large intestine during defecation it is composed of highly
percentage of water and the remnant composed of dead cells, bacteria cells, mucus, indigestible food matter, proteins & cholesterols.
In the meantime, it is normally removed from the body one or two times each day [2].
Sesames (Sesamum indicum, L., Family: Pedaliaceae) was used in nutrition from long past time, many studies confirmed that
Sesames is congaing a high nutritional values, in a study done by Martinchik (2011) confirmed that Sesame seeds contain up to 55%
oil and 20% protein, moreover, this is study mentioned sesames is considered rich with vitamins and fatty acids [3].Also Sesame is
known as highly antioxidant which has grate effects in fatty acids oxidation, synthesis and fatty acids metabolism [4].
Moreover, many studies confirmed the positive effects of sesame in hypotension treatment [5], [6]. In the meantime, sesame oil was
shown appositive effects in lowering the cardiac problem and improve the health of cardiac patents [7], [8], [9]. On the other hand,
in one study done by Liu et al. (2015) found the significant effects in chronic kidney disease of rats when treated with sesame oil
which lead to decrease the level of blood urea nitrogen and creatinine [8].
II. MATERIALS AND METHODS
The study done in two groups each of seven constipation patients, Consequence, those patient were diagnostic with this disease
before at least two years, those patients suffering from difficult stool passage, blood in feces and Pain in stool passage. Then, the
patients are assigned in this this study. One the other hand, the patients are divided into two groups each of seven patients. The first
group is control group and the second group is an experimental group received sesame seeds (500 gram) only as treatment for
constipation two time per day for 21 days. In the meantime, the sesame seeds weight (500 gram) mixed with some sugar as shown in
figure 4. Moreover, the patinas agree to take sesame seeds in this study to evaluate the effects of sesame seeds in constipation for
three weeks.
International Journal for Research in Applied Science & Engineering Technology (IJRASET)
ISSN: 2321-9653; IC Value: 45.98; SJ Impact Factor: 6.887
Volume 7 Issue I, Jan 2019- Available at www.ijraset.com
©IJRASET: All Rights are Reserved 401
A. Statistical Analysis
Mean values of blood parameters and body weights were analyzed by student t- test using computer package program (PASW
statistics 20).
B. The Results
The parameters of duration of emptying bowel, bleeding with feces, difficulty of defecation or discharge and uncomfortable felling
in control and experimental groups taking sesame seeds for 21 days were shown in Table 1 and Figure 1, 2 and 3.
Table 1. Mean values of duration of emptying bowel, bleeding with feces, difficulty of defecation or discharge and uncomfortable
felling in control and experimental groups taking sesame seeds for 21 days (mean ± SD)
Parameters Control
Mean ± SD Experimental
Mean ± SD
Duration of emptying bowel/week 1.29±0.488 5.14±1.67**
Bleeding with feces
1.14±0.378
1.8±0.38**
Difficulty of defecation or discharge
1.4±0.4
1.86±0.37**
Uncomfortable felling after
evacuation
100% Yes
100% No**
*= significant (0.05), ** = highly significant (0.001)
Figure 1: Bleeding in stool in Control group (2) and experimental group (1)
International Journal for Research in Applied Science & Engineering Technology (IJRASET)
ISSN: 2321-9653; IC Value: 45.98; SJ Impact Factor: 6.887
Volume 7 Issue I, Jan 2019- Available at www.ijraset.com
©IJRASET: All Rights are Reserved 402
Figure 2: Difficult in evacuation in Control group (2) and experimental group (1)
Figure 3: unfordable feeling after evacuation in Control group (2) and experimental group (1)
Figure 4: The Sesame seeds
International Journal for Research in Applied Science & Engineering Technology (IJRASET)
ISSN: 2321-9653; IC Value: 45.98; SJ Impact Factor: 6.887
Volume 7 Issue I, Jan 2019- Available at www.ijraset.com
©IJRASET: All Rights are Reserved 403
A. Discussion
Chronic constipation characterized by difficulty in the evacuation, decreased the number of stool per week, with uncomfortable
feeling during the evacuation, excessive squeeze, with unable to complete evacuation.
However, this is study found the positive effects of sesame seeds in treat the symptoms of constipation, such as improving the evacuation
time per week, relive the difficulty during evacuation, reduced the pain during evacuation, all these parameters are observed during the
follow-up period. On the other hand, the sesame seeds don't report before for the treatment of the constipation. Therefore, these positive
effect of sesame seeds might consider a novel effective treatment for constipation. Moreover, this is might due to the central role of
sesame seeds in attracting the water to the intestinal tract. In the meantime, the water is playing a key role in discharge of stool
because it works as lubrication (lubricator factor) during discharge. In the meantime, previous study confirmed the function of water
intake for constipation patients who consumed two liters of water show improvement in the evacuation frequency and a decrease in the
use of laxatives [10]. Also, sesame seeds might include a considerable amount of fibers [11], and the fiber might be facilitating the
discharge process. In this context, the high contains of fibers in diet is recommend by most physicians round the world because
fibers are considered as healthy practice, in this is context, there are many studies recommended to take fiber to treatment
constipation [11], [12].
III. CONCLUSION
In general, the study revealed that sesame seeds help in relieving symptoms of constipation such as hard pass of the stool and
abdominal pain. However, this is need further studies.
IV. RECOMMENDATION
The study recommends the patients of constipation to take sesame seed as an effective treatment without any side effects because it
is naturally hundred percent.
V. ACKNOWLEDGEMENT
The author would thank any person participated in this study especially the patients.
REFERENCES
[1] M. Forootan, N. Bagheri and M. Darvishi. Chronic constipation: A review of literature. “Medicine Journal”. 2018, 97 (20):10631.
[2] C. Rose, A. Parker, B. Jefferson, E. Cartmell. The Characterization of Feces and Urine: A Review of the Literature to Inform Advanced Treatment Technology.
“Crit Rev Environ Sci Technol”. 2015, 2;45(17):1827-1879.
[3] A. Martinchik. Nutritional value of sesame seeds. “Vopr Pitan”, 2011, 80(3):41
[4] Namiki M. Nutraceutical functions of sesame: a review. “Crit Rev Food Sci Nutr.” 2007, 47(7):651-73.
[5] S. Devarajan, R. Singh, B. Chatterjee, B. Zhang, A, Ali. A blend of sesame oil and rice bran oil lowers blood pressure and improves the lipid profile in mild-to-
moderate hypertensive patients. “J Clin Lipidol”. 2016,10(2):339-49.
[6] D. Sankar, M. Rao, G. Sambandam, K. Pugalendi. A pilot study of open label sesame oil in hypertensive diabetics. “J Med Food”. 2006,9(3):408-12.
[7] C. Liu and M. Liu. Daily sesame oil supplementation attenuates local renin-angiotensin system via inhibiting MAPK activation and oxidative stress in cardiac
hypertrophy. “J Nutr Biochem.” 2017 ,42:108-116.
[8] C. Liu, S. Chien , D. Hsu, S. Periasamy , M. Liu. Curative effect of sesame oil in a rat model of chronic kidney disease. “Nephrology (Carlton).” 2015,
20(12):922-30
[9] C. Liu , S. Periasamy, C. Chang, F. Mo, M. Liu. Sesame oil therapeutically ameliorates cardiac hypertrophy by regulating hypokalemia in hypertensive rats.
“JPEN J Parenter Enteral Nutr.” 2014,38(6):750-7.
[10] N. Sabine, T Soraia, C. Francine. Water and fluid intake in the prevention and treatment of functional constipation in children and adolescents: is there evidence.
“J Pediatr”. 2017, 93(4):320-327.
[11] M. Elleuch, D. Bedigian, B. Maazoun, S. Besbes, C. Blecker, H. Attia. Improving halva quality with dietary fibers of sesame seed coats and date pulp, enriched
with emulsifier. “Food Chem.” 2014, 15;145:765-71.
[12] P. Piccoli, D. Eifer, E. Daniel. Use of fibers in childhood constipation treatment: systematic review with meta-analysis. “J Pediatr ”.2018 ,94(5):460-470.
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