Conference Paper

Nanoformulations of encapsulating Essential Oil in polymeric nanocarriers with antioxidant and antibacterial properties

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Abstract

Chitosan (CS) nano-carrier was used as an encapsulating agent for Peppermint Essential Oil (PO) by using two-steps method starting with emulsification and followed by ionic cross-linking method. The PO loaded chitosan colloidal nanoparticles were characterized by different techniques; Dynamic light scattering (DLS), Fourier transform infrared (FT-IR) spectroscopy, Thermogravimetric analysis (TGA), and powder X-ray diffraction (XRD). The morphology and size of CS/PO NPs were detected by Transmission electron microscopy (TEM) that showed spherical shape of the nanoparticles with an average size range below 100 nm. The EE % and LC % of CS/PO NPs reached 82% and 22%, respectively. Moreover, the PO nano-encapsulation improved the PO antioxidant activity by about 2 folds and showed superior antibacterial activity of CS/PO NPs against Staphylococcus aureus and Escherichia coli by about 99.9% and 97.5%, respectively. The results obtained will enhance the usage of nano-encapsulated PO in the Food and Pharmaceutical sectors.

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  • C Hu
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A. Esmaeili and A. Asgari, "In vitro release and biological activities of Carum copticum essential oil (CEO) loaded chitosan nanoparticles," Int. J. Biol. Macromol., vol. 81, pp. 283-290, Nov. 2015. Proceedings of the Nanotech France 2018 International Conference (Nanotech France 2018) Paris, France, June 27 -29, 2018 DOI: https://doi.org/10.26799/cp-nanotechfrance2018 ______________________________________________________________________________________________