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Cognitive Behavioural Therapy through PowerPoint: Efficacy in an Adolescent Clinical Population with Depression and Anxiety

Wiley
International Journal of Pediatrics
Authors:

Abstract

Background: Limited help-seeking behaviours, among adolescents with mental health concerns and many barriers to accessing mental health services, make innovative approaches to administering mental health therapies crucial. Therefore, this study evaluated the efficacy of e-CBT given via PowerPoint slides to treat adolescents with anxiety and/or depression. Method: 15 adolescents referred to an outpatient adolescent psychiatry clinic to treat a primary DSM-IV diagnosis of anxiety and/or depression chose between 8 weeks of e-CBT (n=7) or 7 weeks of live CBT (n=8). The e-CBT modules were presented using PowerPoint delivered weekly through email by either a senior psychiatry resident or an attending physician. Within each session, participants in both groups had personalized feedback on their mandatory weekly homework assignment from the previous week's module. BYIs were completed before treatment and and after final treatment within both groups to assess changes in depression, anxiety, anger, disruption, and self-concept. Findings: Before treatment, BYI scores did not sig. differ between groups. After treatment, e-CBT participants reported sig. improved depression, anger, anxiety, and self-concept BYI scores while live CBT participants did not report any sig. changes. Only the Beck Anxiety Inventory sig. differed between groups after CBT. Conclusion: Despite the low sample size within this study, using email to deliver e-CBT PowerPoint slides and individualized homework feedback shows promise as an alternate method of CBT delivery that reduces barriers to receiving mental health treatment that occur internationally.
Research Article
Cognitive Behavioural Therapy through PowerPoint: Efficacy in
an Adolescent Clinical Population with Depression and Anxiety
Nazanin Alavi ,1,2 Matthew Stefanoff ,2Alyssa Hirji,3and Sarosh Khalid-Khan1
1Department of Psychiatry, Queens University, Providence Care Hospital, 752 King Street West, Postal Bag 603,
Kingston, Ontario, K7L 7X3, Canada
2Department of Psychiatry, University of Toronto, Centre for Addiction and Mental Health, 100 Stokes Street, Toronto,
Ontario, M6J 1H4, Canada
3Department of Psychology, Queens University, Humphrey Hall, Room 232, Queen’s University, Kingston, Ontario, K7L 2N6, Canada
Correspondence should be addressed to Nazanin Alavi; nazanin.alavi@camh.ca
Received 8 July 2018; Accepted 24 October 2018; Published 8 November 2018
Academic Editor: Namik Y. Ozbek
Copyright ©  Nazanin Alavi et al. is is an open access article distributed under the Creative Commons Attribution License,
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background. Limited help-seeking behaviours, among adolescents with mental health concerns and many barriers to accessing
mental health services, make innovative approachesto administering mental health therapies crucial. erefore, this study evaluated
the ecacy of e-CBT given via PowerPoint slides to treat adolescents withanxiety and/or depression. Method.  adolescents referred
to an outpatient adolescent psychiatry clinic to treat a primary DSM-IV diagnosis of anxiety and/or depression chose between
 weeks of e-CBT (n=) or  weeks of live CBT (n=). e e-CBT modules were presented using PowerPoint delivered weekly
through email by either a senior psychiatry resident or an attending physician. Within each session, participants in both groups had
personalized feedback on their mandatory weekly homework assignment from the previous week’s module. BYIs were completed
before treatment and and aer nal treatment within both groups to assess changes in depression, anxiety, anger, disruption, and
self-concept. Findings. Before treatment, BYI scores did not sig. dier between groups. Aer treatment, e-CBTparticipants reported
sig. improved depression, anger, anxiety, and self-concept BYI scores while live CBT participants did not report any sig. changes.
Only the Beck Anxiety Inventory sig. diered between groups aer CBT. Conclusion. Despite the low sample size within this study,
using email to deliver e-CBT PowerPoint slides and individualized homework feedback shows promise as an alternate method of
CBT delivery that reduces barriers to receiving mental health treatment that occur internationally.
1. Introduction
Mental illness is the leading cause of disability among
adolescents worldwide [ ]. In an American study, it was found
that % of adolescents met the diagnostic criteria for at least
one DSM-IV disorder and % of the sample experienced
a severe impairment []. About / of the adolescents met
the diagnostic criteria for an anxiety disorder and %
met the criteria for a mood disorder []. If le untreated,
anxiety and depression can place a signicant burden on the
economy, impair individuals’ daily functioning, and reduce
quality of life [, ]. CBT has eectively improved both
anxiety and depression and so minimizes the strain of these
disorders on economic and personal levels. As every  in -
adolescents has a chronic psychiatric disorder [], CBT may
be particularly important for this young population, as early
therapy is associated with a better long-term prognosis [].
Despite the ecacy of CBT and the benets of early inter-
vention, only % and % of adolescents with depressive
symptoms receive treatment in developed and developing
countries, respectively [, ]. Living in a rural area, a lack
of mental health resources and/or accessibility, and doubt
over the condentiality of treatment perpetuated by negative
stigmas have all been said to negatively impact the availability
and pursuit of treatment [, ]. To combat these barriers,
there has been a surge in the examination of innova-
tive treatments, many involving technology and the inter-
net.
With over . billion people worldwide using the internet
[], the research, development, and use of computer-based
Hindawi
International Journal of Pediatrics
Volume 2018, Article ID 1396216, 5 pages
https://doi.org/10.1155/2018/1396216
International Journal of Pediatrics
CBT (e-CBT) has been booming due to its potential to reduce
many barriers of traditional face-to-face therapies []. E-
CBT is very cost-eective and increases treatment acces-
sibility and adherence to individuals where mental health
resources are lacking [, ]. Many patients have reported
e-CBT as preferable due to its convenience, condentiality,
and reduction of perceived stigma []. Finally, e-CBT has
many practical advantages, such as the individualization of
programs and therefore treatments, along with self-pacing,
the ability to review material, and the ease of record keeping
and data collection []. As most adolescents are familiar and
comfortable with computers and the internet, e-CBT may be
particularly eective for treating mental health concerns of
this age.
While various programs for the online treatment of de-
pression and anxiety exist, many do not have an ecacy
comparable to live treatment. For example, MoodGYM is
a current e-CBT based on cognitive restructuring, pleasant
events scheduling, and interpersonal problem solving [].
It allows the participant to work through material at their
own pace and consists of  sessions to be completed over 
weeks. In a study of the ecacy of MoodGYM, adolescent
st year undergraduates with anxiety or depression were ran-
domised to either live CBT, MoodGYM, both combined, or
no treatment groups. All treatment groups had a reduction
in both depression and anxiety compared to the control
group, but the live CBT group had a greater decline in
depression than those using MoodGYM. Also, the combined
group had signicantly lower anxiety and depression aer
the intervention than the MoodGYM only group []. e
authors suggest that these ndings may be due to MoodGYM
being unsuitable for this age group because of the complexity
of the therapy components or the slow pace of the program
[].
Another program, BRAVE for Teenagers-Online, used for
adolescents with anxiety disorders consists of  one-hour
long sessions which replicate the clinic-based version of the
program while incorporating standard CBT anxiety manage-
ment strategies []. Participants were assigned homework at
the end of each session and had a BRAVE trainer who moni-
tored their work, gave support, and feedback. All participants
were randomised to live CBT, e-CBT, or a wait-list control.
Signicantly more participants in the treatment groups no
longer met the criteria for an anxiety diagnosis aer treatment
than in the control group, with no dierences between the live
and e-CBT groups on ecacy or participant satisfaction [].
e % of adolescents with an anxiety disorder continued to
fall in both groups at the  and  month follow-ups, with
no sig. dierences between the treatment groups []. Taken
together, the MoodGYM and BRAVE ndings suggest that
e-CBT may be as eective as live CBT, but not all e-CBT
programs are equivalent.
is study examines the ecacy of e-CBT delivered
through PowerPoint slides combined with weekly computer-
based psychiatrist-given feedback to adolescents with anxiety
or depression; this study is the rst to examine ecacy using
this treatment modality. We hypothesized that e-CBT would
be as ecacious as live CBT in improving depression and
anxiety.
T : CBT topics by week of administration.
Week Topics Covered
Introduction,Goals
FivePartyModel
oughts
Connection between oughts, feelings,
Behaviour, Physical Reactions and Environment
‘Evidence’ and ‘Alternativeand Balanced
inking’
Experiments and Action Plans
Strategies to overcome the distress
8Summary and Feedback
Module only given to e-CBT participants.
2. Materials & Methods
2.1. Participants. Adolescent males (n= ) and females
(n=)aged-(M=., SD=.) who met DSM-IV
criteria for major depressive disorder and generalized anxiety
disorder were invited to participate in the study. Participants
were recruited from the outpatient Child and Youth Mental
Health Program at the Hotel Dieu Hospital site of the
Kingston Health Sciences Centre in Kingston, Ontario. Each
participant was recommended to participate in CBT for the
treatment of their primary diagnosis.
2.2. Measures. Participants were assessed using the Beck
Youth Inventories (BYI), a self-report instrument used to
assess youth aged -. e measure consists of  composite
scores: the Beck Depression Inventory for Youth (BDI-Y),
the Beck Anxiety Inventory for Youth (BAI-Y), the Beck
Anger Inventory for Youth (BANI-Y), the Beck Disruptive
Inventory for Youth (BDBI-Y), and the Beck Self-Concept
Inventory for Youth (BSCI-Y). Each inventory consists of
items rated on a -point scale from  (never) to  (always).
Total raw scores can range from  to , with higher scores
representing more of the construct.
2.3. Procedure. To maintain a naturalistic study design, each
participant chose between live and e-CBT. e e-CBT ses-
sions were designed to directly mirror the live CBT sessions,
but live CBT consisted of  sessions, whereas the e-CBT
consisted of . e th e-CBT session only collected feedback
without giving any new content, so the live and e-CBT
sessions were considered to be equivalent.
For each online session, participants were sent about -
 PowerPoint slides every Wednesday, consisting of general
information on a weekly topic, an overview of helpful skills
that relate to the weekly topic, and mandatory homework
sheets (Table ). e homework assignments were due every
Sunday. ey were received by either a senior psychiatry
resident or attending physician, who sent each e-CBT partic-
ipant individualized feedback, the next sessions slides, and
corresponding homework via email on the next Wednesday.
Homework completion and submission was mandatory to
progress to the next week’s session. If homework was not
International Journal of Pediatrics
T : Group dierence in BYI scales before receiving any CBT.
e-CBT (n=) Live (n=)
BYI Scale M SD M SD tdfp
BDI-Y . . . . .  .
BAI-Y . . . . -.  .
BANI-Y . . . . -.  .
BDBI-Y . . . . .  .
BSCI-Y . . . , -.  .
returned by the deadline, a reminder email was sent. e
control group had weekly one-hour live CBT sessions, with
matching homework assignments.
e BYI was completed by all participants both before
treatment and aer completing their nal CBT session. All
BYIs were completed within appointments in the clinic for
both live CBT and e-CBT groups.
Descriptive statistics and independent sample t-tests were
used to examine demographic dierences between groups,
while repeated measures analysis of variance (ANOVA)
testing was used to determine the eect of time and treatment
modality on each BYI inventory. Pairwise comparisons were
conducted using a Bonferroni adjustment and all analyses
were done using SPSS.
isstudywasreviewedforethicalcompliancebythe
Research and Ethics Board of Queen’s University, Canada.
3. Results
Of the  study participants,  chose e-CBT and  chose
live CBT. Age was not signicantly dierent between groups
(t()=-., p=.) with the mean age of e-CBT and
live CBT groups being . (SD=.) and . (SD=.),
respectively. Each group had  male participant,  females had
e-CBT, and  had live CBT. Before treatment, the  groups did
not dier signicantly on any BYI scores (Table ).
3.1. BDI-Y. e  groups did not dier signicantly
(F(,)=., p=.) in BDI-Y scores aer treatment: the
e-CBT group had a mean score of . (SD=.) and the
live CBT group a mean score of . (SD=.). Pre- and
posttreatment BDI-Y scores did not dier signicantly within
the live CBT group (F(,)=., p=.), but within the
e-CBT group they fell signicantly over time (F(,)=.,
p=.).
3.2. BAI-Y. BAI-Y scores aer treatment were signicantly
lower (F(, )=., p=.) in the e-CBT group (M=.,
SD=.) than the live CBT group (M=., SD=.).
Additionally, pre- and posttreatment BAI-Y scores within the
live CBT group did not change signicantly (F(,)=.,
p=.), whereas the e-CBT group BAI-Y scores fell signif-
icantly over time (F(,)=., p=.).
3.3. BANI-Y. e e-CBT (M=., SD=.) and live CBT
(M=., SD=.) groups did not signicantly dier
(F(,)=., p=.) on posttreatment BANI-Y scores. e
pre- and posttreatment BANI-Y scores did not dier signif-
icantly within the live CBT group (F(,)=., p=.), but
BANI-Y scores within the e-CBT group fell signicantly over
time (F(,)=., p=.).
3.4. BDBI-Y. e  groups did not dier signicantly (F(,)
=. p=.) in BDBI-Y scores aer treatment, with e-
CBT having a mean score of . (SD=.) and live CBT a
mean of . (SD=.). e pre- and post-treatment BDBI-
Y scores did not dier signicantly over time within the live
CBTgroup (F(,)=., p=.) or within the e-CBT group
(F(,)=., p=.).
3.5. BSCI-Y. e e-CBT (M=., SD=.) and live CBT
(M=., SD=.) groups did not dier signicantly (F(,
) =., p=.) on posttreatment BSCI-Y scores. e pre-
and posttreatment BSCI-Y scores did not dier signicantly
within the live CBT group (F(,)=., p=.), but the e-
CBT BSCI-Y scores rose signicantly over time (F(,)=.,
p=.).
4. Discussion
Results of this study suggest that e-CBT delivered via Pow-
erPoint is eective for improving depression and anxiety in
adolescents. Contrary to expectations, e-CBT via PowerPoint
with clinician-provided feedback may be more eective than
live CBT in reducing symptoms. e e-CBT group improved
signicantly in anxiety, depression, anger, and self-concept
aer treatment, whereas the live CBT group did not improve
signicantly over time in any of the BYI inventories. Despite
the signicant changes in the e-CBT group within  of the
 BYI inventories, the two groups only diered signicantly
posttreatment in anxiety, with e-CBT having signicantly
more reduction in BAI scores than live CBT. e signicance
of e-CBT on BAI scores is important as anxiety disorders
aect / of adolescents [], and unmanaged anxiety disorders
in adolescents correlate with an increased risk of illicit drug
dependence, depression, and academic underachievement
[].
e study’s ndings are unique in that the e-CBT ses-
sions related to signicant improvements in two inventories
not directly related to the adolescents’ primary diagnoses:
anger and self-concept. is suggests that the topics covered
within the e-CBT modules improve not only self-reported
depression and anxiety but also other problems with which
youth presenting to an outpatient psychiatric clinic may have
International Journal of Pediatrics
diculties. Surprisingly, however, this eect was only seen
when the modules were given via PowerPoint e-CBT.
ese ndings are inconsistent with previous ndings of
live CBT being more eective than e-CBT for depression and/
or anxiety in adolescents [, ]. is may be due to the use of
standardized e-CBT programs in previous studies, whereas
the current study used weekly PowerPoint slides with corre-
sponding individualized psychiatrist-provided feedback. is
personalized feedback allows for increased communication
between therapist and client via email and so more closely
resembles traditional face-to-face therapy. is personaliza-
tion of treatment may help explain why this intervention was
more eective than other online CBT programs.
While older research emphasized the negative aspects of
adolescents using the internet, more recently, it was found
to be benecial []. Since many adolescents are wary of
seeking treatment for mental health concerns, the existence
of a more accessible virtual treatment modality may increase
adolescents’ willingness to both seek out and participate in
treatment []. Within this study, a decreased reluctance
to participate in therapy could have led to an increased
engagement with treatment in the e-CBT group, further
contributing to the increased ecacy of e-CBT compared to
live CBT.
isstudywaslimitedbythesmallsamplesizeand
lack of treatment modality randomization. e absence of
randomization may introduce additional confounding vari-
ables. However, by giving patients the option to choose their
CBT delivery method, this study is a naturalistic approach to
examining ecacy by mirroring the decisions made in clini-
cal settings. Also, participants’ comfor t with using computers,
emails, and PowerPoint may have inuenced the ecacy of
e-CBT []. Since no measures were employed to evaluate
comfort with these technologies and programs, this is a
possible confounder and so it is likely that those comfortable
with computers chose the e-CBT option, potentially inating
the results of that group.
Future research should determine the eec ts of familiarity
with computers as a confounding variable on the ecacy of
e-CBT, in addition to randomizing the treatment modality
between patients to determine if the results of this study
were inuenced by patients’ ability to choose their method
of receiving CBT. Further studies of the ecacy of e-CBT via
PowerPoint in adolescents would also benet from a longer
follow-up period to determine the duration of the treatment
eects. However, previous studies examining e-CBT via
PowerPoint for depression given to adults were immediately
eective and the results were evident at the -month follow-
up [].
5. Conclusion
While further studies are warranted due to the small sample
size of the current study, they are the rst to show that
computer-based CBT via PowerPoint slides may be an eec-
tive way to improve depression and anxiety in adolescents.
is simple, innovative and user-friendly way to deliver CBT
to adolescents might reduce barriers to treatment such as
lack of resources, missing class for appointments, and the
high costs of soware development. It may be particularly
benecial for adolescents comfortable with technology who
may be concerned with stigma associated with attending live
CBT, by allowing treatment to be completed at home. Also,
this method of e-CBT may be more eective than other
standardized e-CBT programs previously examined because
it can be quickly and easily tailored to meet the needs of
each individual patient. Not only can the therapist address
individual concerns or elaborate on material when needed,
but e-CBT also can be easily adapted for other languages or
cultures that have specic needs. us, e-CBT via PowerPoint
is an innovative therapy that has promise as a new way to
deliver CBT to improve adolescent depression and anxiety
and can remove barriers that prevent youth from receiving
mental health treatment.
Data Availability
e data used to support the ndings of this study are
available in excel format in the following link: https://
docs.google.com/spreadsheets/d/yLsvPOLXcERXd rAu-
oTNbnkwohAhAQxYzIFPKA/edit?usp=sharing. e
data can also be obtained by the corresponding author upon
request.
Conflicts of Interest
e authors declare that they have no conicts of interest.
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... Self-help, guided, and asynchronous deliveries have all shown effectiveness in symptom management, with results showing comparable improvements in in-person CBT, medications, and control groups [13][14][15][16][17]. e-CBT has also been shown to improve resilience and quality of life, in addition to depressive symptom management [17]. The predesigned therapy content of e-CBT enables clinicians to disseminate core and standardized elements of the therapy at a considerably faster rate [18][19][20][21][22]. This distinguishing feature of e-CBT can contribute to a broader audience reach and shorten wait times [21]. ...
... This pilot study had a pre-post single-arm design. Since the efficacy of the e-CBT intervention in mitigating GAD and MDD symptoms has already been established in previous trials [18][19][20][21][22], this study focused on the pre-post effects of participating in the e-CBT program during the COVID-19 pandemic. Moreover, since the trial was conducted at the beginning of the pandemic, it was important to observe the pre-post effects in a pilot study and subsequently use that data to inform a randomized controlled trial (RCT). ...
... The therapy's engaging modules were also customized to reflect common challenges faced by individuals with MDD and GAD during the COVID-19 pandemic. These modules were adapted from previous clinical trials, which used a similar approach to treating depression and anxiety [18][19][20][21][22]. ...
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Background: Lockdowns and social distancing resulting from the COVID-19 pandemic have worsened the population's mental health and made it more difficult for individuals to receive care. Electronic cognitive behavioural therapy (e-CBT) is a cost-effective and evidence-based treatment for anxiety and depression that can be accessed remotely. Objective: The objective of the study was to investigate the efficacy of online psychotherapy tailored to depression and anxiety symptoms during the pandemic. Methods: The pilot study used a pre-post design to evaluate the efficacy of a 9-week e-CBT program designed for individuals with depression and anxiety affected by the pandemic. Participants were adults (n = 59) diagnosed with major depressive disorder and/or generalized anxiety disorder, whose mental health symptoms initiated or worsened during the COVID-19 pandemic. The online psychotherapy program focused on teaching coping, mindfulness, and problem-solving skills. Symptoms of anxiety and depression, resilience, and quality of life were assessed. Results: Participants demonstrated significant improvements in symptoms of anxiety (p = 0.023) and depression (p = 0.029) after the intervention. Similar trends were observed in the intent-to-treat analysis. No significant differences were observed in resilience and quality of life measures. The sample comprised mostly females, making it challenging to discern the benefits of the intervention in males. Although a pre-post design is less rigorous than a controlled trial, this design was selected to observe changes in scores during a critical period. Conclusions: e-CBT for COVID-19 is an effective and accessible treatment option. Improvements in clinical symptoms of anxiety and depression can be observed in individuals whose mental health is affected by COVID-19. Clinicaltrial: ClinicalTrials.gov NCT04476667. International registered report: RR2-10.2196/24913.
... The structured nature of CBT has allowed it to be effectively adapted into a web-based format (electronically delivered CBT; e-CBT) where patients can access standard concepts remotely and in their own time. While e-CBT has already proven productive and scalable for treating anxiety disorders [10,[16][17][18][19], developing less-intensive interventions that still benefit patients could allow for even more scalability. Not all patients may require the full structure of e-CBT and could still benefit from a less-intensive option, such as structured mental health conversations with a care provider. ...
... During this training, therapists complete feedback on practice homework, which is reviewed to ensure adequate quality of work. All care providers are supervised by a licensed therapist [10][11][12]16,[24][25][26] who will review feedback before submission. Table 1. ...
... CBT is currently one of the first-line treatments for GAD, but it tends to be inaccessible to patients and requires a high level of time commitment from mental health care professionals. Using the internet to deliver mental health treatments has become a promising solution in recent years, with e-CBT being scalable, accessible, and effective in treating GAD [16][17][18][32][33][34]. Now that e-CBT is an effective treatment option for patients with GAD, understanding ways to tailor the care to each patient, with varying intensity levels, is crucial for the future of scalability [11,12,16,[24][25][26]. ...
Article
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Background: Generalized anxiety disorder (GAD) is a prevalent anxiety disorder with cognitive behavioural therapy (CBT) being the gold-standard treatment. However, it is inaccessible and costly to many as the mental health industry is overwhelmed by the demand for treatment. This means effective, accessible, and time-saving strategies must be developed to combat these problems. Online interventions for mental health disorders are an innovative and promising way to address these barriers. While the electronic delivery of CBT (e-CBT) has already proved productive and scalable for treating anxiety, other less resource-intensive interventions can be innovated. Checking up on one's mental health face to face has been shown to provide similar benefits to patients with anxiety disorders previously, but more research is needed to evaluate the efficacy of online delivery of this intervention. Objective: This study will compare the efficacy of e-CBT and a virtual mental health check-in program to treat GAD. These programs will both be delivered through a secure, online, care delivery platform. Methods: Participants (n = 100) over 18 years with a confirmed diagnosis of GAD will be randomly allocated to either an e-CBT program or a mental health check-in program over 12 weeks to address their anxiety symptoms. Participants in the e-CBT arm will complete pre-designed modules and homework assignments while receiving personalized feedback and asynchronous interaction with a therapist through the platform. Participants in the mental health check-in arm will be contacted weekly through the online platform's written chat feature (messaging system). Therapists will ask the participants a series of pre-designed questions that revolve around a different theme each week to prompt conversation. Using clinically validated questionnaires, the efficacy of the e-CBT arm will be compared to the mental health check-in arm. These questionnaires will be completed at baseline, week 6, and week 12. Results: The study received ethics approval in April 2021 and participant recruitment began in May 2021. Participant recruitment has been conducted through targeted advertisements and physician referrals. Complete data collection and analysis are expected to conclude by August 20223. Linear and binomial regression (continuous and categorical outcomes respectively) will be conducted. Conclusions: To the research team's knowledge, this will be the first study, to date, comparing the efficacy of e-CBT with an online mental health check-in program to treat GAD. The findings from this study can help progress the development of more scalable, accessible, and efficacious mental health treatments. Clinicaltrial: clinicaltrials.gov (NCT04754438).
... For instance, one RCT study observed significantly lower depressive symptom scale scores at posttest compared to those in the enhanced usual care (EUC) group; however, the remission rates for depression did not differ significantly between groups [20]. Other studies indicated significantly higher remission rates of depression in iCBT group compared with the online psychoeducation group [21], and lower but nonsignificant depressive symptom scores in the iCBT group when compared with an offline CBT group [22]. Previous systematic reviews have indicated that among adolescents, iCBT can effectively reduce depressive symptom severity and improve remission rate of depression when compared with controls such as treatment-as-usual (TAU), wait-list, and notreatment [23][24][25]. ...
Article
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Objective This study aimed to evaluate the acceptability and effects of internet‐based cognitive behavioral therapy (iCBT) or CBT‐oriented interventions compared with control groups on depressive symptoms, remission of depression, and quality of life (QOL) in adolescents. Methods We searched English and Chinese databases for randomized controlled trials up to October 10, 2024 that investigated the effects of iCBT compared with controls in adolescents exhibiting elevated depressive symptoms or diagnosed with depression. Standardized mean differences (SMDs), relative risks (RRs), and 95% confidence intervals were applied to evaluate the pooled effects of outcomes. Results A total of 19 RCTs involving 3574 cases were included in this study. We found small effects on depressive symptoms severity at different time points (posttest: SMD = –0.49 [–0.66, –0.33]; 3‐month follow‐up [FU3]: SMD = –0.21 [–0.30, –0.11]; FU6: SMD = –0.18 [–0.35, –0.02]; FU12: SMD = –0.38 [–0.56, –0.20]). We also found a significant effect in depression remission rate at the posttest (RR = 1.74 [1.36, 2.21]) and a significant effect in QOL at the posttest (SMD = 0.30 [0.07, 0.54]). However, the result regarding acceptability was nonsignificant (RR = 1.22 [0.76, 1.97]). No significant publication bias was found in these results. Conclusion iCBT or internet‐based CBT‐oriented interventions can effectively reduce depressive symptom severity and improve depression remission rate and QOL in depressed adolescents. These results are preliminary and require further validation through future systematic reviews.
... The e-CBT sessions used in this study include content based on cognitive restructuring and behavioural activation techniques (45). The purpose of the sessions is to help participants become aware of inaccurate or negative thinking patterns so that they can view challenging situations more clearly and respond to them effectively. ...
Article
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Introduction Depression is a leading cause of disability worldwide, affecting up to 300 million people globally. Despite its high prevalence and debilitating effects, only one-third of patients newly diagnosed with depression initiate treatment. Electronic cognitive behavioural therapy (e-CBT) is an effective treatment for depression and is a feasible solution to make mental health care more accessible. Due to its online format, e-CBT can be combined with variable therapist engagement to address different care needs. Typically, a multi-professional care team determines which combination therapy most benefits the patient. However, this process can add to the costs of these programs. Artificial intelligence (AI) has been proposed to offset these costs. Methods This study is a double-blinded randomized controlled trial recruiting individuals experiencing depression. The degree of care intensity a participant will receive will be randomly decided by either: (1) a machine learning algorithm, or (2) an assessment made by a group of healthcare professionals. Subsequently, participants will receive depression-specific e-CBT treatment through the secure online platform. There will be three available intensities of therapist interaction: (1) e-CBT; (2) e-CBT with a 15–20-min phone/video call; and (3) e-CBT with pharmacotherapy. This approach aims to accurately allocate care tailored to each patient’s needs, allowing for more efficient use of resources. Discussion Artificial intelligence and providing patients with varying intensities of care can increase the efficiency of mental health care services. This study aims to determine a cost-effective method to decrease depressive symptoms and increase treatment adherence to online psychotherapy by allocating the correct intensity of therapist care for individuals diagnosed with depression. This will be done by comparing a decision-making machine learning algorithm to a multi-professional care team. This approach aims to accurately allocate care tailored to each patient’s needs, allowing for more efficient use of resources with the convergence of technologies and healthcare. Ethics The study received ethics approval and began participant recruitment in December 2022. Participant recruitment has been conducted through targeted advertisements and physician referrals. Complete data collection and analysis are expected to conclude by August 2024. Clinical trial registration ClinicalTrials.Gov, identifier NCT04747873.
... Many studies show e-CBT to be effective in treating anxiety symptoms, with differing levels of effectiveness across delivery modalities, with digital self-help interventions being extremely popular (29)(30)(31)(32)(33). While self-help programs do offer benefits, the incorporation of therapist engagement can further increase effectiveness (33)(34)(35). One form of e-CBT delivery is live psychotherapy (synchronous delivery through video calls with the patient). ...
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Background Generalized anxiety disorder (GAD) is a debilitating mental health disorder with first-line treatments include cognitive behavioral therapy (CBT) and pharmacotherapy. CBT is costly, time-consuming, and inaccessible. Electronic delivery (e-CBT) is a promising solution to address these barriers. However, due to the novelty of this intervention, more research testing the e-CBT efficacy independently and in conjunction with other treatments is needed. Objective This study investigated the efficacy of e-CBT compared to and in conjunction with pharmacotherapy for GAD. Methods This study employed a quasi-experimental design where patients selected their preferred treatment modality. Patients with GAD were enrolled in either e-CBT, medication, or combination arms. The 12-week e-CBT program was delivered through a digital platform. The medications followed clinical guidelines. The efficacy of each arm was evaluated using questionnaires measuring depression, anxiety, and stress severity, as well as quality of life. Results There were no significant differences between arms (N e-CBT = 41; N Medication = 41; N Combination = 33) in the number of weeks completed or baseline scores. All arms showed improvements in anxiety scores after treatment. The medication and combination arms improved depression scores. The e-CBT and Combination arms improved quality of life, and the combination arm improved stress scores. There were no differences between the groups in depression, anxiety, or stress scores post-treatment. However, the combination arm had a significantly larger improvement in quality of life. Gender and treatment arm were not predictors of dropout, whereas younger age was. Conclusion Incorporating e-CBT on its own or in combination with pharmaceutical interventions is a viable option for treating GAD. Treating GAD with e-CBT or medication appears to offer significant improvements in symptoms, with no meaningful difference between the two. Combining the treatments also offer significant improvements, while not necessarily superior to either independently. The findings suggest that all options are viable. Taking the patient’s preferred treatment route based on their lifestyle, personality, and beliefs into account when deciding on treatment should be a priority for care providers.
... All therapists were psychotherapy-trained research assistants with backgrounds and training in psychotherapy. The therapists were hired by the principal investigator (PI), a clinician-scientist with expertise in CBT and electronically delivered psychotherapy (23,28,35,(40)(41)(42)(43). Therapists were also instructed to complete CBT courses and workshops as part of their training. ...
Article
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Objective The increased prevalence of major depressive disorder (MDD) amid the COVID-19 pandemic has resulted in substantial growth in online mental health care delivery. Compared to its in-person counterpart, online cognitive behavioral therapy (e-CBT) is a time-flexible and cost-effective method of improving MDD symptoms. However, how its efficacy compares to in-person CBT is yet to be explored. Therefore, the current study compared the efficacy of a therapist-supported, electronically delivered e-CBT program to in-person therapy in individuals diagnosed with MDD. Methods Participants (n = 108) diagnosed with MDD selected either a 12 week in-person CBT or an asynchronous therapist-supported e-CBT program. E-CBT participants (n = 55) completed weekly interactive online modules delivered through a secure cloud-based online platform (Online Psychotherapy Tool; OPTT). These modules were followed by homework in which participants received personalized feedback from a trained therapist. Participants in the in-person CBT group (n = 53) discussed sessions and homework with their therapists during one-hour weekly meetings. Program efficacy was evaluated using clinically validated symptomatology and quality of life questionnaires. Results Both treatments yielded significant improvements in depressive symptoms and quality of life from baseline to post-treatment. Participants who opted for in-person therapy presented significantly higher baseline symptomatology scores than the e-CBT group. However, both treatments demonstrated comparable significant improvements in depressive symptoms and quality of life from baseline to post-treatment. e-CBT seems to afford higher participant compliance as dropouts in the e-CBT group completed more sessions on average than those in the in-person CBT group. Conclusion The findings support e-CBT with therapist guidance as a suitable option to treat MDD. Future studies should investigate how treatment accessibility is related to program completion rates in the e-CBT vs. in-person group. Clinical Trial Registration ClinicalTrials.Gov Protocol Registration and Results System (NCT04478058); clinicaltrials.gov/ct2/show/NCT04478058.
... Using the pilot data collected along with understanding the feasibility of the described protocol, this can be used as a stepping stone for a larger-scaled randomized-controlled trial (RCT) in the future. The electronic delivery method for the psychotherapy program (OPTT) has been proven feasible in previous work (28,41,51) and was again found to be easy to implement and use as an online psychotherapy delivery platform. Regarding functional neuroimaging, the block design with the previously described imaging parameters was effective at capturing high-quality imaging with sensitivity to changes in neural activity. ...
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Background Obsessive–compulsive disorder (OCD) is a debilitating mental health disorder with current psychotherapeutic treatments, while somewhat effective, yielding low accessibility and scalability. A lack of knowledge regarding the neural pathology of OCD may be hindering the development of innovative treatments. Previous research has observed baseline brain activation patterns in OCD patients, elucidating some understanding of the implications. However, by using neuroimaging to observe the effects of treatment on brain activation, a more complete picture of OCD can be drawn. Currently, the gold standard treatment is cognitive behavioral therapy (CBT). However, CBT is often inaccessible, time-consuming, and costly. Fortunately, it can be effectively delivered electronically (e-CBT). Objectives This pilot study implemented an e-CBT program for OCD and observed its effects on cortical activation levels during a symptom provocation task. It was hypothesized that abnormal activations could be attenuated following treatment. Methods OCD patients completed a 16-week e-CBT program administered through an online platform, mirroring in-person content. Treatment efficacy was evaluated using behavioral questionnaires and neuroimaging. Activation levels were assessed at the resting state and during the symptom provocation task. Results In this pilot, seven participants completed the program, with significant improvements (p < 0.05) observed between baseline and post-treatment for symptom severity and levels of functioning. No statistically significant (p = 0.07) improvement was observed in the quality of life. Participants had mostly positive qualitative feedback, citing accessibility benefits, comprehensive formatting, and relatable content. No significant changes in cortical activation were observed between baseline and post-treatment. Conclusion This project sheds light on the application of e-CBT as a tool to evaluate the effects of treatment on cortical activation, setting the stage for a larger-scale study. The program showed great promise in feasibility and effectiveness. While there were no significant findings regarding changes in cortical activation, the trends were in agreeance with previous literature, suggesting future work could provide insight into whether e-CBT offers comparable cortical effects to in-person psychotherapy. Applying a greater knowledge of the neural mechanisms of action in OCD can help develop novel treatment plans in the future.
Article
Background Generalized anxiety disorder (GAD) is a prevalent anxiety disorder characterized by uncontrollable worry, trouble sleeping, muscle tension, and irritability. Cognitive behavioural therapy (CBT) is one of the first-line treatments that has demonstrated high efficacy in reducing symptoms of anxiety. Electronically delivered CBT (e-CBT) has been a promising adaptation of in-person treatment, showing comparable efficacy with increased accessibility and scalability. Finding further scalable interventions that can offer benefits to patients requiring less intensive interventions can allow for better resource allocation. Some studies have indicated that weekly check-ins can also lead to improvements in GAD symptoms. However, there is a lack of research exploring the potential benefits of online check-ins for patients with GAD. Objective This study aims to investigate the effects of weekly online asynchronous check-ins on patients diagnosed with GAD and compare it with a group receiving e-CBT. Methods Participants ( n e-CBT = 45; n check-in = 51) with GAD were randomized into either an e-CBT or a mental health check-in program for 12 weeks. Participants in the e-CBT program completed pre-designed modules and homework assignments through a secure online delivery platform where they received personalized feedback from a trained care provider. Participants in the mental health check-in condition had weekly asynchronous messaging communication with a care provider where they were asked structured questions with a different weekly theme to encourage conversation. Results Both treatments demonstrated statistically significant reductions in GAD—7-item questionnaire (GAD-7) scores over time, but when comparing the groups there was no significant difference between the treatments. The number of participants who dropped out and baseline scores on all questionnaires were comparable for both groups. Conclusions The findings support the effectiveness of e-CBT and mental health check-ins for the treatment of GAD.
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Background: Alcohol use disorder (AUD) is characterized by problematic alcohol use accompanied by clinically significant distress. Patients with AUD frequently experience high relapse rates and only one in five remain abstinent 12 months post-treatment. Traditional face-to-face relapse prevention treatment (RPT) is a form of cognitive behavioural therapy that examines one's situational triggers, maladaptive thought processes, self-efficacy, and motivation. However, access to this treatment is frequently limited due to its high cost, long waitlists, and inaccessibility. An online adaptation of RPT (e-RPT) could address these limitations by providing a more cost-effective and accessible delivery method for mental health care in this population. Objective: This study protocol aims to establish the first academic e-RPT program to address AUD in the general population. The primary objective of this study is to compare the efficacy of e-RPT to face-to-face RPT at decreasing relapse rates. The secondary objective is to assess the effects of e-RPT on quality of life, self-efficacy, resilience, and depressive symptomatology. The tertiary objective is to evaluate cost-effectiveness of e-RPT compared to face-to-face RPT. Methods: Adult participants (n = 60) with a confirmed diagnosis of AUD will be randomly assigned to receive ten sessions of e-RPT or face-to-face RPT. e-RPT will consist of 10 predesigned modules and homework with asynchronous personalized feedback from a therapist. Face-to-face RPT will comprise 10 one-hour face-to-face sessions with a therapist. The predesigned modules and the face-to-face sessions will present the same content and structure. Self-efficacy, resilience, depressive symptomatology, and alcohol consumption will be measured through various questionnaires at baseline, mid-treatment, and end of treatment. Results: Participant recruitment is expected to begin in October 2022 through targeted advertisements and physician referrals. Completed data collection and analysis are expected to conclude by October 2023. Outcome data will be assessed using linear and binomial regression (continuous and categorical outcomes respectively). Qualitative data will be analyzed using thematic analysis methods. Conclusions: The current study will be the first to examine the effectiveness of e-RPT compared to face-to-face RPT. It is posited that online care can present benefits in terms of accessibility and affordability compared to traditional face-to-face psychotherapy. Clinicaltrial: clinicaltrials.gov (NCT05579210).
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Mental and substance use disorders are common and often persistent, with many emerging in early life. Compared to adult mental and substance use disorders, the global burden attributable to these disorders in children and youth has received relatively little attention. Data from the Global Burden of Disease Study 2010 was used to investigate the burden of mental and substance disorders in children and youth aged 0-24 years. Burden was estimated in terms of disability-adjusted life years (DALYs), derived from the sum of years lived with disability (YLDs) and years of life lost (YLLs). Globally, mental and substance use disorders are the leading cause of disability in children and youth, accounting for a quarter of all YLDs (54.2 million). In terms of DALYs, they ranked 6th with 55.5 million DALYs (5.7%) and rose to 5th when mortality burden of suicide was reattributed. While mental and substance use disorders were the leading cause of DALYs in high-income countries (HICs), they ranked 7th in low- and middle-income countries (LMICs) due to mortality attributable to infectious diseases. Mental and substance use disorders are significant contributors to disease burden in children and youth across the globe. As reproductive health and the management of infectious diseases improves in LMICs, the proportion of disease burden in children and youth attributable to mental and substance use disorders will increase, necessitating a realignment of health services in these countries.
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Background Greater access to evidence-based psychological treatments is needed. This review aimed to evaluate whether internet-delivered psychological treatments for mood and anxiety disorders are efficacious, noninferior to established treatments, safe, and cost-effective for children, adolescents and adults. Methods We searched the literature for studies published until March 2013. Randomized controlled trials (RCTs) were considered for the assessment of short-term efficacy and safety and were pooled in meta-analyses. Other designs were also considered for long-term effect and cost-effectiveness. Comparisons against established treatments were evaluated for noninferiority. Two reviewers independently assessed the relevant studies for risk of bias. The quality of the evidence was graded using an international grading system. Results A total of 52 relevant RCTs were identified whereof 12 were excluded due to high risk of bias. Five cost-effectiveness studies were identified and three were excluded due to high risk of bias. The included trials mainly evaluated internet-delivered cognitive behavioral therapy (I-CBT) against a waiting list in adult volunteers and 88% were conducted in Sweden or Australia. One trial involved children. For adults, the quality of evidence was graded as moderate for the short-term efficacy of I-CBT vs. waiting list for mild/moderate depression (d = 0.83; 95% CI 0.59, 1.07) and social phobia (d = 0.85; 95% CI 0.66, 1.05), and moderate for no efficacy of internet-delivered attention bias modification vs. sham treatment for social phobia (d = −0.04; 95% CI −0.24, 0.35). The quality of evidence was graded as low/very low for other disorders, interventions, children/adolescents, noninferiority, adverse events, and cost-effectiveness. Conclusions I-CBT is a viable treatment option for adults with depression and some anxiety disorders who request this treatment modality. Important questions remain before broad implementation can be supported. Future research would benefit from prioritizing adapting treatments to children/adolescents and using noninferiority designs with established forms of treatment.
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Despite the efficacy of cognitive-behavioral therapy (CBT) in treating adolescent anxiety, few sufferers seek treatment. Barriers to accessing psychologists include a shortage of skilled therapists, long waiting lists, and affordability. The Internet is a medium possibly able to address issues of accessibility and affordability. This study aimed to assess the efficacy of online therapy in the treatment and prevention of adolescent anxiety and depression. Participants (N = 38) were randomly allocated to one of four conditions: online CBT, face-to-face CBT, combined face-to-face/online CBT, and control. Combined face-to-face/online CBT is more effective in treating symptoms of depression and anxiety compared to stand-alone online or face-to-face therapy. The present study suggests that for those who are unable to access face-to-face therapy, computerized therapy may be a viable option. This is an important finding, especially in light of current capacity to treat and accessibility problems faced in the treatment of adolescent depression and anxiety.
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The study examined the relative efficacy of online (NET) versus clinic (CLIN) delivery of cognitive behavior therapy (CBT) in the treatment of anxiety disorders in adolescents. Participants included 115 clinically anxious adolescents aged 12 to 18 years and their parent(s). Adolescents were randomly assigned to NET, CLIN, or wait list control (WLC) conditions. The treatment groups received equivalent CBT content. Clinical diagnostic interviews and questionnaire assessments were completed 12 weeks after baseline and at 6- and 12-month follow-ups. Assessment at 12 weeks post-baseline showed significantly greater reductions in anxiety diagnoses and anxiety symptoms for both NET and CLIN conditions compared with the WLC. These improvements were maintained or further enhanced for both conditions, with minimal differences between them, at 6- and 12-month follow-ups. Seventy-eight percent of adolescents in the NET group (completer sample) no longer met criteria for the principal anxiety diagnosis at 12-month follow-up compared with 80.6% in the CLIN group. Ratings of treatment credibility from both parents and adolescents were high for NET and equivalent to CLIN. Satisfaction ratings by adolescents were equivalent for NET and CLIN conditions, whereas parents indicated slightly higher satisfaction ratings for the CLIN format. Online delivery of CBT, with minimal therapist support, is equally efficacious as clinic-based, face-to-face therapy in the treatment of anxiety disorders among adolescents. This approach offers a credible alternative to clinic-based therapy, with benefits of reduced therapist time and greater accessibility for families who have difficulty accessing clinic-based CBT.
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Some studies of computerized cognitive behaviour therapy (CCBT) have found evidence of its effectiveness, yet a number have reported low uptake and/or completion rates. This study investigated attitudes towards CCBT for depression amongst 122 university students. The credibility of CCBT, expectancy-for-improvement and perceived likelihood of using it were all poor, although a minority (9.8%) stated a preference for CCBT over other interventions. When 20 of the original sample received a demonstration of a CCBT programme for depression, significant increases in credibility, expectancy-for-improvement and in perceived likelihood of using CCBT were found. Numbers stating a preference for CCBT increased to 30%. At both stages, most students stated a preference for CCBT to be accompanied by counselling. Qualitative analysis provided information about factors that might influence these attitudes. Implications for service delivery are discussed.
Article
Objective: The goal of this study was to evaluate the efficacy of weekly email in delivering online cognitive behavioral therapy (CBT) to treat mild to moderately depressed individuals. The effectiveness of the online CBT was measured following treatment and then again at a 6-month follow-up and was compared with outcomes in a waitlist control group. Methods: Participants were recruited through announcements on psychology Web sites, Iranian organization Web sites, and weblogs and flyers. Ninety-three individuals who met inclusion criteria, including a score >18 on the Beck Depression Inventory (BDI), participated in the study, with 47 randomly assigned to the CBT group and 46 to the control group. The CBT group received 10 to 12 sessions of online CBT conducted by a psychiatrist and a psychiatry resident. Following completion of the CBT, a second BDI was sent to participants. Another BDI was then sent to participants 6 months after the completion of treatment. Results: Email-based CBT significantly reduced BDI scores compared with results in a waitlist control group following 10 to 12 weeks of treatment and at 6-month follow-up. Conclusions: Email is a viable method for delivering CBT to individuals when face-to-face interaction is not possible. Limitations and future directions are discussed.
Article
Adolescents are currently the defining users of the Internet. They spend more time online than adults do, and they use the Internet for social interaction more often than adults do. This article discusses the state of the literature on the consequences of online communication technologies (e.g., instant messaging) for adolescents' social connectedness and well-being. Whereas several studies in the 1990s suggested that Internet use is detrimental, recent studies tend to report opposite effects. We first explain why the results of more recent studies diverge from those of earlier studies. Then, we discuss a viable hypothesis to explain the recent findings: the Internet-enhanced self-disclosure hypothesis. Finally, we discuss some contingent factors that may deserve special attention in future research.
Article
Some studies of computerized cognitive behaviour therapy (CCBT) have found evidence of its effectiveness, yet a number have reported low uptake and/or completion rates. This study investigated attitudes towards CCBT for depression amongst 122 university students. The credibility of CCBT, expectancy-for-improvement and perceived likelihood of using it were all poor, although a minority (9.8%) stated a preference for CCBT over other interventions. When 20 of the original sample received a demonstration of a CCBT programme for depression, significant increases in credibility, expectancy-for-improvement and in perceived likelihood of using CCBT were found. Numbers stating a preference for CCBT increased to 30%. At both stages, most students stated a preference for CCBT to be accompanied by counselling. Qualitative analysis provided information about factors that might influence these attitudes. Implications for service delivery are discussed.
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Short-term Effects of Early InterventionA Developmental Framework for Early InterventionThe Early Intervention SystemLong-term Effectiveness of Early InterventionSummary and Conclusions