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A Meta-Analysis of the Association Between Patients’ Early Treatment
Outcome Expectation and Their Posttreatment Outcomes
Michael J. Constantino
University of Massachusetts Amherst
Andreea Vîsla
˘
University of Zurich
Alice E. Coyne
University of Massachusetts Amherst
James F. Boswell
University at Albany, State University of New York
Patients’ outcome expectation (OE) represents their belief about the mental health consequences of
participating in psychotherapy. A previous meta-analysis of 46 independent samples receiving the
treatment of at least 3 sessions revealed a significant association between more optimistic baseline, or
early treatment, OE and more adaptive posttreatment outcomes (weighted r⫽.12 or d⫽.24;
Constantino, Glass, Arnkoff, Ametrano, & Smith, 2011). The present study represents an update to that
meta-analysis. To be included, articles published through June 2017 had to (a) include a clinical sample,
(b) include a therapist-delivered treatment of at least 3 sessions, (c) include a measure of patients’ own
OE, (d) include at least 1 posttreatment mental health outcome not explicitly referenced as a follow-up
occasion, and (e) report a statistical test of the OE⫺outcome association. The updated meta-analysis was
conducted on 81 independent samples (extracted from 72 references) with 12,722 patients. The overall
weighted effect size was r⫽.18, p⬍.001, or d⫽.36, with high heterogeneity (I
2
⫽76%) and no
evidence of publication bias. Several variables (patient age, measure type, and treatment manual used)
moderated the OE⫺outcome association. These robust, replicated meta-analytic findings are discussed in
light of methodological limitations and with regard to their practice implications.
Clinical Impact Statement
Question: This article examined the association between patients’ presenting, or early treatment,
expectation for a given treatment’s helpfulness and their outcomes after treatment ends. Findings:
Patient outcome expectation (OE) is an empirically supported correlate of treatment outcome that
therapists need to assess throughout treatment, attempt to heighten at treatment’s outset, and respond
to sensitively if/when it wanes. Meaning: The OE⫺improvement correlation increases the scientific
credibility of formerly ill-named “nonspecific” factors like expectancies; thus, there is sufficient
information to incorporate systematically OE-fostering and OE-restoring strategies into clinical
practice and training. Next Steps: Future research needs to (a) test strategies that causally enhance
patients’ OE to improve treatment efficacy and (b) illuminate both patient and therapist contributions
to patient OE to help tailor clinical practice and training.
Keywords: psychotherapy, patient outcome expectation, psychotherapy relationship, psychotherapy
outcome, meta-analysis
Supplemental materials: http://dx.doi.org/10.1037/pst0000169.supp
Patients’ expectations have long been considered a key ingre-
dient and common factor of successful psychotherapy (Frank,
1961;Goldfried, 1980;Goldstein, 1960a;Rosenzweig, 1936). In
his classic, Persuasion and Healing,Frank (1961) argued that
patients enter therapy because they are demoralized, and that for
any therapy to be effective, there must be within the patient a
mobilization of belief in the ability to improve. To Frank, this
positive outcome expectation (OE) precipitates a sense of remor-
Michael J. Constantino, Department of Psychological and Brain Sciences,
University of Massachusetts Amherst; Andreea Vîsla
˘, Department of Psychology,
University of Zurich; Alice E. Coyne, Department of Psychological and Brain
Sciences, University of Massachusetts Amherst; James F. Boswell, Department of
Psychology, University at Albany, State University of New York.
This article is adapted, by special permission of Oxford University Press,
by the same authors in J. C. Norcross & M. J. Lambert (Eds.) (2018),
Psychotherapy relationships that work (3rd ed.). New York, NY: Oxford
University Press. The Interdivisional APA Task Force on Evidence-Based
Psychotherapy Relationships and Responsiveness was cosponsored by the
APA Division of Psychotherapy/Society for the Advancement of Psycho-
therapy.
Correspondence concerning this article should be addressed to Michael
J. Constantino, Department of Psychological and Brain Sciences, Univer-
sity of Massachusetts Amherst, 135 Hicks Way, Amherst, MA 01003-
9271. E-mail: mconstantino@psych.umass.edu
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Psychotherapy © 2018 American Psychological Association
2018, Vol. 55, No. 4, 473–485 0033-3204/18/$12.00 http://dx.doi.org/10.1037/pst0000169
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