interior-boundary conditions (IBC's) allow for the direct description of the domain and the action of Hamiltonians for a certain class of ultraviolet-divergent models in Quantum Field Theory. The method was recently applied to models where nonrelativistic scalar particles are linearly coupled to a quantised field, the best known of which is the Nelson model. Since this approach avoids the use of ultraviolet-cutoffs, there is no need for a renormalisation procedure. Here, we extend the IBC method to pseudorelativistic scalar particles that interact with a real bosonic field. We construct the Hamiltonians for such models via abstract boundary conditions, describing their action explicitly. In addition, we obtain a detailed characterisation of their domain and make the connection to renormalisation techniques. As an example, we apply the method to two relativistic variants of Nelson's model, which have been renormalised for the first time by J. P. Eckmann and A. D. Sloan in 1970 and 1974, respectively.