The number of refugees and displaced persons around the world has reached historic levels. Education in Emergencies responses have traditionally focused on primary education with higher education opportunities often having been perceived as a luxury. Current statistics on refugee access to education confirms this ongoing trend: 50% of refugee children access primary education, 22% secondary education, and only 1% higher education. Children and youth are particularly vulnerable to losing their right to education, a basic human right that is enshrined in the 1989 Convention on the Rights of the Child and the 1951 Refugee Convention, and is essential to the exercise of many other human rights. In 2015, the United Nations adopted the Sustainable Development Goals, thereby broadening the education mandate to include lifelong learning. Refugee youth have extremely limited options in conflict and crisis zones. However, rapid advances in technology and online learning have laid the foundations for making higher education opportunities accessible for refugee youth. Education fosters innovation and entrepreneurial skills that are important for employability, economic activity, and job creation—elements that are critical for stability during times of reconstruction and for longer term sustainable development. If refugees and internally displaced persons receive a quality education while in exile, they are more likely to develop the necessary skills to make use of the existing economic, social, and political systems in their host communities as well as upon returning home. This paper analyzes the contribution of Open Educational Resources (OERs) to building twenty-first-century skills and explores the value of tutoring and mentoring models, learner retention, learning technologies, and provision of language and subject matter support that best mediate higher level learning in fragile contexts. Variables such as sustainability, operability, equal access, cultural and linguistic ownership, livelihoods, and context relevance were used to analyze available evidence in an effort to inform optimal design and scalability of such learning spaces, as well as their potential use in migrant refugee contexts. The importance of refugee ownership and empowerment are emphasized as vectors for ensuring the sustainability of HE spaces in fragile contexts and for fostering creativity and innovation, thereby feeding into the larger framework of Education for All and Sustainable Development Goal 4.