The development of entrepreneurship is increasingly considered an effective method to increase access to safe drinking water and sanitation. In this study, 80 Micro-entrepreneurs (78 female) selling water filters in East Java, Indonesia were surveyed in 2016 to determine the motives for self-employment, perceived success factors, and challenges encountered. Results reveal that the primary reasons for selling the water filters were income generation, helping others, use past training and experience, and learning. Results show that the water filter entrepreneurs were driven by monetary motives as well as intrinsic and altruistic factors. Business virtues such as honesty and friendliness were ranked highest amongst the business success variables. Serious problems faced by the micro-entrepreneurs were the weak economy, difficulty convincing clients and low margins. Results on success factors and perceived problems and obstacles are consistent with results from previous studies using similar instruments in Turkey, Vietnam and Canada. Previous studies did not include altruistic motives, which were valued as very important by respondents in this survey. Compared to female entrepreneurs in Canada, the Indonesian entrepreneurs are more motivated by money and less by intrinsic reasons, similar to their peers in Turkey and Serbia. Entrepreneurs that score themselves high on presentation skills and those who are motivated by creating income have on average higher sales. On the other hand, entrepreneurs that are motivated by helping the staff of the principal and those who think that adequate education is important sell less. The findings can be used for a better selection of potential water and sanitation entrepreneurs. In addition, programs supporting entrepreneurship should make sure that:1) the money generating potential is high enough; 2) downline creation is encouraged and 3) training is provided to increase presentation skills.